Details for: PDE1C

Gene ID: 5137

Symbol: PDE1C

Ensembl ID: ENSG00000154678

Description: phosphodiesterase 1C

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 183.1706
    Cell Significance Index: -46.4600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.3821
    Cell Significance Index: -33.6700
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 12.7438
    Cell Significance Index: 110.2300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.7637
    Cell Significance Index: -46.4200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 10.3597
    Cell Significance Index: 226.8400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 6.9814
    Cell Significance Index: 535.7400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.2931
    Cell Significance Index: 1456.3300
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.5309
    Cell Significance Index: 11.8000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.5050
    Cell Significance Index: 84.4500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.4795
    Cell Significance Index: 2728.5900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.4560
    Cell Significance Index: 277.0800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.3735
    Cell Significance Index: 275.5200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.0287
    Cell Significance Index: 107.1100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9475
    Cell Significance Index: 855.5100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9126
    Cell Significance Index: 90.2800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.8890
    Cell Significance Index: 21.3200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8722
    Cell Significance Index: 603.2200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.8620
    Cell Significance Index: 32.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.8250
    Cell Significance Index: 36.4900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6557
    Cell Significance Index: 40.3000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5855
    Cell Significance Index: 210.0000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.5106
    Cell Significance Index: 785.9800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.4654
    Cell Significance Index: 13.2800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3475
    Cell Significance Index: 56.5100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2964
    Cell Significance Index: 558.1400
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.2189
    Cell Significance Index: 3.0800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1190
    Cell Significance Index: 2.0400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1116
    Cell Significance Index: 12.1400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0525
    Cell Significance Index: 71.3700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0508
    Cell Significance Index: 0.7300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0192
    Cell Significance Index: 0.4800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0023
    Cell Significance Index: 0.0800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0014
    Cell Significance Index: 0.0400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0193
    Cell Significance Index: -2.8000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0414
    Cell Significance Index: -18.7900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0450
    Cell Significance Index: -33.3600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0516
    Cell Significance Index: -22.8100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0558
    Cell Significance Index: -40.8800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0583
    Cell Significance Index: -31.8400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0659
    Cell Significance Index: -49.9100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0704
    Cell Significance Index: -1.0400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0770
    Cell Significance Index: -48.1100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0772
    Cell Significance Index: -43.5700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0774
    Cell Significance Index: -3.5100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0842
    Cell Significance Index: -5.8300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0910
    Cell Significance Index: -0.5500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.1300
    Cell Significance Index: -23.4400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1345
    Cell Significance Index: -38.6900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.1420
    Cell Significance Index: -2.3400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1755
    Cell Significance Index: -34.8200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1791
    Cell Significance Index: -3.8800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2030
    Cell Significance Index: -42.7600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2289
    Cell Significance Index: -39.0900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2335
    Cell Significance Index: -7.4800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2521
    Cell Significance Index: -3.6100
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.2583
    Cell Significance Index: -3.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.2698
    Cell Significance Index: -37.0600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2732
    Cell Significance Index: -27.9100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2812
    Cell Significance Index: -5.5600
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.2835
    Cell Significance Index: -3.0400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3021
    Cell Significance Index: -34.6100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3060
    Cell Significance Index: -39.2300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3066
    Cell Significance Index: -18.8000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3124
    Cell Significance Index: -38.4100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3224
    Cell Significance Index: -41.6500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3253
    Cell Significance Index: -6.5300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3266
    Cell Significance Index: -38.0600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3397
    Cell Significance Index: -15.9700
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.3410
    Cell Significance Index: -5.4100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4099
    Cell Significance Index: -13.0600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.4205
    Cell Significance Index: -5.2200
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.4453
    Cell Significance Index: -5.7100
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -0.4755
    Cell Significance Index: -5.9100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4904
    Cell Significance Index: -29.4400
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.5408
    Cell Significance Index: -6.5600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5419
    Cell Significance Index: -28.4500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5465
    Cell Significance Index: -36.7500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5959
    Cell Significance Index: -11.6300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.6118
    Cell Significance Index: -45.6000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6152
    Cell Significance Index: -21.5500
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.6283
    Cell Significance Index: -7.3300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.6911
    Cell Significance Index: -35.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7391
    Cell Significance Index: -46.5800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.7749
    Cell Significance Index: -49.9900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.7879
    Cell Significance Index: -41.0400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.8143
    Cell Significance Index: -26.6600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.8796
    Cell Significance Index: -41.0100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.9313
    Cell Significance Index: -20.1200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9786
    Cell Significance Index: -20.7700
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.9927
    Cell Significance Index: -9.4100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.0335
    Cell Significance Index: -22.0100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -1.0525
    Cell Significance Index: -15.8600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -1.0776
    Cell Significance Index: -11.7400
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -1.0836
    Cell Significance Index: -21.3300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.1016
    Cell Significance Index: -27.4800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -1.1145
    Cell Significance Index: -27.0000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.1257
    Cell Significance Index: -31.4600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -1.1485
    Cell Significance Index: -23.9700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.1659
    Cell Significance Index: -42.8000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.1874
    Cell Significance Index: -41.2600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PDE1C is a dual-specificity phosphodiesterase, meaning it can degrade both cAMP and cGMP. This characteristic allows it to modulate multiple signaling pathways, including those mediated by G-proteins and calmodulin. PDE1C is also known to be activated by calmodulin, a calcium-binding protein, which suggests a link between calcium signaling and PDE1C activity. Additionally, PDE1C has been shown to interact with other proteins, such as PLCβ, which further underscores its role in regulating cellular signaling. **Pathways and Functions:** PDE1C is involved in several key signaling pathways, including: 1. **Ca-dependent events:** PDE1C is activated by calmodulin, which binds to calcium ions in the cytosol. This binding event triggers the degradation of cGMP, a key second messenger involved in calcium signaling. 2. **Calmodulin-activated 3',5'-cyclic-gmp phosphodiesterase activity:** PDE1C can degrade cGMP, which in turn modulates the activity of various downstream targets, including ion channels and transcription factors. 3. **Ca-dependent signaling:** PDE1C can also regulate the activity of other phosphodiesterases, such as PDE4, which further modulates calcium signaling. 4. **G-protein mediated events:** PDE1C has been shown to interact with G-proteins, which are involved in regulating a wide range of cellular processes, including cell signaling and gene expression. 5. **Intracellular signaling by second messengers:** PDE1C can degrade cAMP and cGMP, which are key second messengers involved in regulating cellular processes, including gene expression and cell signaling. **Clinical Significance:** Dysregulation of PDE1C has been implicated in various diseases, including: 1. **Neurological disorders:** PDE1C has been shown to play a role in regulating neuronal function and development, and dysregulation of PDE1C has been implicated in conditions such as Parkinson's disease and cerebral ischemia. 2. **Cardiac disorders:** PDE1C has been shown to regulate cardiac contractility and relaxation, and dysregulation of PDE1C has been implicated in conditions such as heart failure and cardiac arrhythmias. 3. **Sensory perception:** PDE1C has been shown to play a role in regulating sensory perception, and dysregulation of PDE1C has been implicated in conditions such as migraine and sensory neuropathy. In conclusion, PDE1C is a critical regulator of cellular signaling pathways, and dysregulation of this gene has been implicated in various diseases. Further research is needed to fully elucidate the role of PDE1C in regulating cellular function and to explore its potential as a therapeutic target for disease treatment.

Genular Protein ID: 2011784894

Symbol: PDE1C_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q14123 B3KPC6 E9PE92 Q14124 Q8NB10

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 19 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EC 1 EMBL 10 Ensembl 4 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 11 Rhea 6 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8557689

Title: Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.

PubMed ID: 8557689

DOI: 10.1074/jbc.271.2.796

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 29860631

Title: A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss.

PubMed ID: 29860631

DOI: 10.1007/s00439-018-1895-y

Sequence Information:

  • Length: 709
  • Mass: 80760
  • Checksum: 77133D4DDBE5F7C0
  • Sequence:
    • MESPTKEIEE FESNSLKYLQ PEQIEKIWLR LRGLRKYKKT SQRLRSLVKQ LERGEASVVD 
LKKNLEYAAT VLESVYIDET RRLLDTEDEL SDIQSDAVPS EVRDWLASTF TRQMGMMLRR 
SDEKPRFKSI VHAVQAGIFV ERMYRRTSNM VGLSYPPAVI EALKDVDKWS FDVFSLNEAS 
GDHALKFIFY ELLTRYDLIS RFKIPISALV SFVEALEVGY SKHKNPYHNL MHAADVTQTV 
HYLLYKTGVA NWLTELEIFA IIFSAAIHDY EHTGTTNNFH IQTRSDPAIL YNDRSVLENH 
HLSAAYRLLQ DDEEMNILIN LSKDDWREFR TLVIEMVMAT DMSCHFQQIK AMKTALQQPE 
AIEKPKALSL MLHTADISHP AKAWDLHHRW TMSLLEEFFR QGDREAELGL PFSPLCDRKS 
TMVAQSQVGF IDFIVEPTFT VLTDMTEKIV SPLIDETSQT GGTGQRRSSL NSISSSDAKR 
SGVKTSGSEG SAPINNSVIS VDYKSFKATW TEVVHINRER WRAKVPKEEK AKKEAEEKAR 
LAAEEQQKEM EAKSQAEEGA SGKAEKKTSG ETKNQVNGTR ANKSDNPRGK NSKAEKSSGE 
QQQNGDFKDG KNKTDKKDHS NIGNDSKKTD GTKQRSHGSP APSTSSTCRL TLPVIKPPLR 
HFKRPAYASS SYAPSVSKKT DEHPARYKML DQRIKMKKIQ NISHNWNRK

Genular Protein ID: 3178902420

Symbol: A0A0A0MS69_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MS69

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 22 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 1 PROSITE 3 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 6 RuleBase 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 769
  • Mass: 86925
  • Checksum: D8B757D86377C0D5
  • Sequence:
    • MTDAGNRKEG FKKCRSATFS IDGYSFTIVA NEAGDKNARP LARFSRSKSQ NCLWNSLIDG 
LTGNVKEKPR PTIVHDPRPP EEILADELPQ LDSPEVLVKT SFRLRSLVKQ LERGEASVVD 
LKKNLEYAAT VLESVYIDET RRLLDTEDEL SDIQSDAVPS EVRDWLASTF TRQMGMMLRR 
SDEKPRFKSI VHAVQAGIFV ERMYRRTSNM VGLSYPPAVI EALKDVDKWS FDVFSLNEAS 
GDHALKFIFY ELLTRYDLIS RFKIPISALV SFVEALEVGY SKHKNPYHNL MHAADVTQTV 
HYLLYKTGVA NWLTELEIFA IIFSAAIHDY EHTGTTNNFH IQTRSDPAIL YNDRSVLENH 
HLSAAYRLLQ DDEEMNILIN LSKDDWREFR TLVIEMVMAT DMSCHFQQIK AMKTALQQPE 
AIEKPKALSL MLHTADISHP AKAWDLHHRW TMSLLEEFFR QGDREAELGL PFSPLCDRKS 
TMVAQSQVGF IDFIVEPTFT VLTDMTEKIV SPLIDETSQT GGTGQRRSSL NSISSSDAKR 
SGVKTSGSEG SAPINNSVIS VDYKSFKATW TEVVHINRER WRAKVPKEEK AKKEAEEKAR 
LAAEEQQKEM EAKSQAEEGA SGKAEKKTSG ETKNQVNGTR ANKSDNPRGK NSKAEKSSGE 
QQQNGDFKDG KNKTDKKDHS NIGNDSKKTD GTKQRSHGSP APSTSSTCRL TLPVIKPPLR 
HFKRPAYASS SYAPSVSKKT DEHPARYKML DQRIKMKKIQ NISHNWNRK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.