Details for: TRAPPC4

Gene ID: 51399

Symbol: TRAPPC4

Ensembl ID: ENSG00000196655

Description: trafficking protein particle complex subunit 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 191.9056
    Cell Significance Index: -29.8500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 130.3602
    Cell Significance Index: -33.0700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 90.4214
    Cell Significance Index: -42.6900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 87.4626
    Cell Significance Index: -36.0300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 83.4939
    Cell Significance Index: -33.9200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 75.7409
    Cell Significance Index: -38.9600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 63.8205
    Cell Significance Index: -42.8300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 35.7793
    Cell Significance Index: -34.1600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 29.9119
    Cell Significance Index: -36.8800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.9072
    Cell Significance Index: -26.5400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.7769
    Cell Significance Index: -38.5800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.0748
    Cell Significance Index: -21.7300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.9021
    Cell Significance Index: -8.5400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 2.0893
    Cell Significance Index: 243.4800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.0700
    Cell Significance Index: 54.4300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.9858
    Cell Significance Index: 16.6800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.9306
    Cell Significance Index: 115.9000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1213
    Cell Significance Index: 30.5200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.8613
    Cell Significance Index: 105.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.8358
    Cell Significance Index: 52.6800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8045
    Cell Significance Index: 110.4800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.7975
    Cell Significance Index: 9.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7950
    Cell Significance Index: 41.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7616
    Cell Significance Index: 415.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6806
    Cell Significance Index: 122.6900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6643
    Cell Significance Index: 34.8800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.6144
    Cell Significance Index: 43.4500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5871
    Cell Significance Index: 75.2700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5729
    Cell Significance Index: 253.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5486
    Cell Significance Index: 25.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5406
    Cell Significance Index: 40.2900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.5138
    Cell Significance Index: 24.1500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.5077
    Cell Significance Index: 4.6800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4999
    Cell Significance Index: 34.5700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.4849
    Cell Significance Index: 14.2400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3978
    Cell Significance Index: 13.8300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3843
    Cell Significance Index: 38.0200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3795
    Cell Significance Index: 24.4900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3531
    Cell Significance Index: 41.6500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3065
    Cell Significance Index: 6.6400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2987
    Cell Significance Index: 59.9100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2174
    Cell Significance Index: 41.3700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1557
    Cell Significance Index: 3.2600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1547
    Cell Significance Index: 19.9900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1421
    Cell Significance Index: 50.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1363
    Cell Significance Index: 27.0400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1293
    Cell Significance Index: 89.4400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0691
    Cell Significance Index: 3.4900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0548
    Cell Significance Index: 9.3600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0208
    Cell Significance Index: 39.1400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0145
    Cell Significance Index: 10.6400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0063
    Cell Significance Index: 4.7500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0033
    Cell Significance Index: 0.1500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0026
    Cell Significance Index: 0.0700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0014
    Cell Significance Index: 0.0400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0134
    Cell Significance Index: -9.9200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0140
    Cell Significance Index: -25.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0188
    Cell Significance Index: -29.0200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0254
    Cell Significance Index: -0.4300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0255
    Cell Significance Index: -34.7000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0294
    Cell Significance Index: -3.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0297
    Cell Significance Index: -0.8600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0329
    Cell Significance Index: -20.8900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0360
    Cell Significance Index: -22.4900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0474
    Cell Significance Index: -5.4400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0481
    Cell Significance Index: -27.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0546
    Cell Significance Index: -1.7500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0618
    Cell Significance Index: -28.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0856
    Cell Significance Index: -18.0200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0988
    Cell Significance Index: -2.7600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1309
    Cell Significance Index: -4.6000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1416
    Cell Significance Index: -40.7300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1456
    Cell Significance Index: -3.3700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1559
    Cell Significance Index: -22.6600
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1562
    Cell Significance Index: -2.2200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.1823
    Cell Significance Index: -29.6500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1926
    Cell Significance Index: -7.8900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2071
    Cell Significance Index: -5.2900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2143
    Cell Significance Index: -24.4600
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.2680
    Cell Significance Index: -2.1400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2895
    Cell Significance Index: -15.0800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3119
    Cell Significance Index: -5.3500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3172
    Cell Significance Index: -25.1200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3498
    Cell Significance Index: -36.4200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.3836
    Cell Significance Index: -4.1700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3872
    Cell Significance Index: -29.7200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3928
    Cell Significance Index: -22.0400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4287
    Cell Significance Index: -5.1100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4333
    Cell Significance Index: -4.4900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4471
    Cell Significance Index: -11.9600
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.4640
    Cell Significance Index: -4.9300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4879
    Cell Significance Index: -10.3900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.6307
    Cell Significance Index: -15.7700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.6419
    Cell Significance Index: -14.0600
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.6463
    Cell Significance Index: -9.0700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6487
    Cell Significance Index: -8.8500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6512
    Cell Significance Index: -19.1800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6617
    Cell Significance Index: -17.0100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6749
    Cell Significance Index: -41.3800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.7435
    Cell Significance Index: -11.1400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TRAPPC4 is a conserved gene across species, with high sequence identity between human and other mammals. The protein encoded by TRAPPC4 is a small, multifunctional protein with a molecular weight of approximately 14 kDa. It is a subunit of the TRAPPC complex, which is composed of multiple subunits and is involved in various cellular processes, including protein trafficking and autophagy. TRAPPC4 has been shown to interact with other proteins involved in cell signaling and immune function, such as Rab GTPases and syntaxins. **Pathways and Functions** TRAPPC4 is involved in multiple cellular pathways, including: 1. **Protein Trafficking**: TRAPPC4 is involved in the transport of proteins and lipids within the cell, including the transport of proteins to the Golgi apparatus and the endoplasmic reticulum. 2. **Autophagy**: TRAPPC4 is involved in the regulation of autophagy, a process by which cells recycle damaged or dysfunctional proteins and organelles. 3. **Cell Signaling**: TRAPPC4 interacts with other proteins involved in cell signaling, including Rab GTPases and syntaxins. 4. **Immune Function**: TRAPPC4 is expressed in immune cells, including T cells and mast cells, and is involved in the regulation of immune responses. **Clinical Significance** Dysregulation of TRAPPC4 has been implicated in various diseases, including: 1. **Immunodeficiency Disorders**: Mutations in TRAPPC4 have been associated with immunodeficiency disorders, such as severe combined immunodeficiency (SCID). 2. **Neurological Disorders**: TRAPPC4 has been implicated in the regulation of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer**: TRAPPC4 has been shown to be overexpressed in certain types of cancer, including breast cancer and lung cancer. In conclusion, TRAPPC4 is a multifaceted gene involved in various cellular processes, including protein trafficking, autophagy, and immune function. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the functions and mechanisms of TRAPPC4.

Genular Protein ID: 4189206053

Symbol: TPPC4_HUMAN

Name: Hematopoietic stem/progenitor cell protein 172

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 10810093

Title: Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.

PubMed ID: 10810093

DOI: 10.1101/gr.10.5.703

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11805826

Title: Functional organization of the yeast proteome by systematic analysis of protein complexes.

PubMed ID: 11805826

DOI: 10.1038/415141a

PubMed ID: 19416478

Title: TRAPPC2L is a novel, highly conserved TRAPP-interacting protein.

PubMed ID: 19416478

DOI: 10.1111/j.1600-0854.2009.00906.x

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21525244

Title: C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking.

PubMed ID: 21525244

DOI: 10.1091/mbc.e10-11-0873

PubMed ID: 31794024

Title: Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability.

PubMed ID: 31794024

DOI: 10.1093/brain/awz374

Sequence Information:

  • Length: 219
  • Mass: 24340
  • Checksum: C6ADE525B7CFB731
  • Sequence:
  • MAIFSVYVVN KAGGLIYQLD SYAPRAEAEK TFSYPLDLLL KLHDERVLVA FGQRDGIRVG 
    HAVLAINGMD VNGRYTADGK EVLEYLGNPA NYPVSIRFGR PRLTSNEKLM LASMFHSLFA 
    IGSQLSPEQG SSGIEMLETD TFKLHCYQTL TGIKFVVLAD PRQAGIDSLL RKIYEIYSDF 
    ALKNPFYSLE MPIRCELFDQ NLKLALEVAE KAGTFGPGS

Genular Protein ID: 2846534611

Symbol: E9PQE8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 176
  • Mass: 19483
  • Checksum: 1D40F30334E5182F
  • Sequence:
  • MAIFSVYVVN KAGGLIYQLD SYAPRAEAEK TFSYPLDLLL KLHDERVLVA FGQRDGIRVG 
    HAVLAINGMD VNGRLFAIGS QLSPEQGSSG IEMLETDTFK LHCYQTLTGI KFVVLADPRQ 
    AGIDSLLRKI YEIYSDFALK NPFYSLEMPI RCELFDQNLK LALEVAEKAG TFGPGS

Genular Protein ID: 3107634260

Symbol: E9PKS9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 126
  • Mass: 14150
  • Checksum: E44CC4EA3C0A8B91
  • Sequence:
  • MAIFSVYVVN KAGGLIYQLD SYAPRAEAEK TFSYPLDLLL KLHDERVLVA FGQRDGIRGI 
    KFVVLADPRQ AGIDSLLRKI YEIYSDFALK NPFYSLEMPI RCELFDQNLK LALEVAEKAG 
    TFGPGS

Genular Protein ID: 748024217

Symbol: J3KP27_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 181
  • Mass: 19996
  • Checksum: 911B54A749F791F4
  • Sequence:
  • MAIFSVYVVN KAGGLIYQLD SYAPRAEAEK TFSYPLDLLL KLHDERVLVA FGQRDGIRVG 
    HAVLAINGMD VNGRYTADGK EVLEYLGNPA NYPVSIRFGR PRLTSNEKLM LASMFHSLFA 
    IGSQLSPEQG SSGIEMLETD TFKLHCYQTL TEMPIRCELF DQNLKLALEV AEKAGTFGPG 
    S

Genular Protein ID: 1517681883

Symbol: B4DF86_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 181
  • Mass: 20074
  • Checksum: 80EB54BA980E5D10
  • Sequence:
  • MAIFSVYVVN KAGGLIYQLD SYAPRAEAEK TFSYPLDLLL KLHDERVLVA FGQRYSIRVG 
    HAVLAINGMD VNGRYTADGK EVLEYLGNPA NYPVSIRFGR PRLTSNEKLM LASMFHSLFA 
    IGSQLSPEQG SSGIEMLETD TFKLHCYQTL TEMPIRCELF DQNLKLALEV AEKAGTFGPG 
    S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.