Details for: REV1

Gene ID: 51455

Symbol: REV1

Ensembl ID: ENSG00000135945

Description: REV1 DNA directed polymerase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 311.2278
    Cell Significance Index: -48.4100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 193.2438
    Cell Significance Index: -49.0200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 104.0619
    Cell Significance Index: -49.1300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 96.6629
    Cell Significance Index: -39.2700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 89.0189
    Cell Significance Index: -45.7900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 42.0696
    Cell Significance Index: -51.8700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 41.3200
    Cell Significance Index: -39.4500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.6974
    Cell Significance Index: -44.7300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 16.1031
    Cell Significance Index: -49.4600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.2728
    Cell Significance Index: -52.3800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.7039
    Cell Significance Index: -25.6200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.2604
    Cell Significance Index: 30.8400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.0539
    Cell Significance Index: 57.4000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.9330
    Cell Significance Index: 387.7500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.8900
    Cell Significance Index: 375.0800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.8764
    Cell Significance Index: 27.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6453
    Cell Significance Index: 162.7600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.6061
    Cell Significance Index: 261.2100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.5980
    Cell Significance Index: 19.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.5207
    Cell Significance Index: 116.7000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.3629
    Cell Significance Index: 26.6000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.2801
    Cell Significance Index: 149.1900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2502
    Cell Significance Index: 448.4300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.2116
    Cell Significance Index: 45.8800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.1878
    Cell Significance Index: 52.5400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.1547
    Cell Significance Index: 29.6800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.1517
    Cell Significance Index: 64.6300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.0614
    Cell Significance Index: 28.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.0300
    Cell Significance Index: 69.2600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.9429
    Cell Significance Index: 25.2700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8937
    Cell Significance Index: 806.9600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.8350
    Cell Significance Index: 102.6700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7604
    Cell Significance Index: 82.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6259
    Cell Significance Index: 38.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6027
    Cell Significance Index: 108.6600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.5585
    Cell Significance Index: 13.9600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5144
    Cell Significance Index: 26.7200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4917
    Cell Significance Index: 67.5200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.4749
    Cell Significance Index: 12.6800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3662
    Cell Significance Index: 10.5500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3393
    Cell Significance Index: 150.0200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.3369
    Cell Significance Index: 8.0800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3121
    Cell Significance Index: 21.5900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3005
    Cell Significance Index: 5.1500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2847
    Cell Significance Index: 155.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2601
    Cell Significance Index: 13.6600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2530
    Cell Significance Index: 476.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1946
    Cell Significance Index: 123.5900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1783
    Cell Significance Index: 274.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1722
    Cell Significance Index: 6.0500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1499
    Cell Significance Index: 6.8000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1358
    Cell Significance Index: 250.4100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1269
    Cell Significance Index: 6.6100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1165
    Cell Significance Index: 22.1700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1126
    Cell Significance Index: 5.2500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0854
    Cell Significance Index: 116.1200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0717
    Cell Significance Index: 32.5400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0703
    Cell Significance Index: 9.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0385
    Cell Significance Index: 1.8100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0210
    Cell Significance Index: 0.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0077
    Cell Significance Index: 0.9100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0145
    Cell Significance Index: -2.4800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0150
    Cell Significance Index: -11.1400
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.0169
    Cell Significance Index: -0.1500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0173
    Cell Significance Index: -12.7000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0222
    Cell Significance Index: -3.2300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0266
    Cell Significance Index: -20.1700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0301
    Cell Significance Index: -0.8600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0354
    Cell Significance Index: -22.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0412
    Cell Significance Index: -23.2300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0796
    Cell Significance Index: -5.6300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0907
    Cell Significance Index: -11.7200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0970
    Cell Significance Index: -6.2600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0973
    Cell Significance Index: -1.4000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0982
    Cell Significance Index: -6.1900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1118
    Cell Significance Index: -11.4200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1118
    Cell Significance Index: -1.6500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1216
    Cell Significance Index: -25.6200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1507
    Cell Significance Index: -43.3700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2124
    Cell Significance Index: -3.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2301
    Cell Significance Index: -26.3600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2329
    Cell Significance Index: -17.3600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2678
    Cell Significance Index: -27.8800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3005
    Cell Significance Index: -6.4000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3522
    Cell Significance Index: -12.2400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3597
    Cell Significance Index: -11.5200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3877
    Cell Significance Index: -44.2500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3890
    Cell Significance Index: -11.1500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3908
    Cell Significance Index: -6.5400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.4007
    Cell Significance Index: -6.7500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4617
    Cell Significance Index: -12.1400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4689
    Cell Significance Index: -5.5900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4918
    Cell Significance Index: -38.9500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.5169
    Cell Significance Index: -4.7600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6518
    Cell Significance Index: -39.9600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.7234
    Cell Significance Index: -10.8400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7279
    Cell Significance Index: -17.7600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7959
    Cell Significance Index: -25.3500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.8131
    Cell Significance Index: -6.6300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.8236
    Cell Significance Index: -17.4800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **DNA Polymerase Activity:** REV1 exhibits DNA-directed DNA polymerase activity, allowing it to synthesize new DNA strands while bypassing DNA lesions. 2. **Error-Free Translesion Synthesis:** REV1 is capable of performing error-free translesion synthesis, a process that involves the synthesis of new DNA strands without introducing errors. 3. **DNA Repair:** REV1 is involved in the repair of DNA damage, including interstrand crosslinks, which are lesions that can cause genomic instability. 4. **Y-Family DNA Polymerases:** REV1 belongs to the Y-family of DNA polymerases, which are characterized by their ability to perform error-free translesion synthesis and DNA repair. **Pathways and Functions:** 1. **Damaged DNA Binding:** REV1 binds to damaged DNA, allowing it to bypass lesions and maintain genome stability. 2. **Deoxycytidyl Transferase Activity:** REV1 exhibits deoxycytidyl transferase activity, which is necessary for the synthesis of new DNA strands. 3. **Dna Damage Bypass:** REV1 is involved in the bypass of DNA lesions, including interstrand crosslinks, which can cause genomic instability. 4. **Error-Prone Translesion Synthesis:** REV1 can also perform error-prone translesion synthesis, which can lead to mutations and genomic instability. 5. **Metal Ion Binding:** REV1 binds to metal ions, which are necessary for its enzymatic activity. **Clinical Significance:** 1. **Cancer Prevention:** REV1's ability to perform error-free translesion synthesis and DNA repair may contribute to the prevention of cancer by maintaining genome stability. 2. **Genomic Instability:** REV1's involvement in DNA repair and translesion synthesis may also contribute to the development of genomic instability, which is a hallmark of many cancers. 3. **Immunological Disorders:** REV1's expression in immune cells may also have implications for the prevention of immunological disorders, such as autoimmune diseases and immunodeficiencies. 4. **Radiation Resistance:** REV1's ability to perform error-free translesion synthesis may also contribute to radiation resistance, as it allows cells to bypass DNA lesions caused by radiation. In conclusion, REV1 is a crucial enzyme involved in the repair and replication of DNA. Its ability to perform error-free translesion synthesis and DNA repair has significant implications for the prevention of cancer and other diseases. Further research on REV1 is necessary to fully understand its role in maintaining genome stability and preventing disease.

Genular Protein ID: 3418313135

Symbol: REV1_HUMAN

Name: DNA repair protein REV1

UniProtKB Accession Codes:

Q9UBZ9 O95941 Q53SI7 Q9C0J4 Q9NUP2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 4 CORUM 1 CTD 1 CarbonylDB 1 ChEBI 9 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 8 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 13 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 16 PDBsum 16 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 4 RefSeq 7 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10536157

Title: The human REV1 gene codes for a DNA template-dependent dCMP transferase.

PubMed ID: 10536157

DOI: 10.1093/nar/27.22.4468

PubMed ID: 10760286

Title: The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light.

PubMed ID: 10760286

DOI: 10.1073/pnas.97.8.4186

PubMed ID: 11278384

Title: Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain.

PubMed ID: 11278384

DOI: 10.1074/jbc.m008082200

PubMed ID: 11485998

Title: Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7.

PubMed ID: 11485998

DOI: 10.1074/jbc.m102051200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 10094488

Title: Identification of novel interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains.

PubMed ID: 10094488

DOI: 10.1016/s0014-5793(99)00151-9

PubMed ID: 12529368

Title: Structure and enzymatic properties of a stable complex of the human REV1 and REV7 proteins.

PubMed ID: 12529368

DOI: 10.1074/jbc.m211765200

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20164194

Title: Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1.

PubMed ID: 20164194

DOI: 10.1074/jbc.m109.092403

PubMed ID: 22266823

Title: Regulation of Rev1 by the Fanconi anemia core complex.

PubMed ID: 22266823

DOI: 10.1038/nsmb.2222

Sequence Information:

  • Length: 1251
  • Mass: 138248
  • Checksum: 010E261D537DBA80
  • Sequence:
    • MRRGGWRKRA ENDGWETWGG YMAAKVQKLE EQFRSDAAMQ KDGTSSTIFS GVAIYVNGYT 
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 
GRLLSYIPYQ LYTKQSSVQK GLSFNPVCRP EDPLPGPSNI AKQLNNRVNH IVKKIETENE 
VKVNGMNSWN EEDENNDFSF VDLEQTSPGR KQNGIPHPRG STAIFNGHTP SSNGALKTQD 
CLVPMVNSVA SRLSPAFSQE EDKAEKSSTD FRDCTLQQLQ QSTRNTDALR NPHRTNSFSL 
SPLHSNTKIN GAHHSTVQGP SSTKSTSSVS TFSKAAPSVP SKPSDCNFIS NFYSHSRLHH 
ISMWKCELTE FVNTLQRQSN GIFPGREKLK KMKTGRSALV VTDTGDMSVL NSPRHQSCIM 
HVDMDCFFVS VGIRNRPDLK GKPVAVTSNR GTGRAPLRPG ANPQLEWQYY QNKILKGKAA 
DIPDSSLWEN PDSAQANGID SVLSRAEIAS CSYEARQLGI KNGMFFGHAK QLCPNLQAVP 
YDFHAYKEVA QTLYETLASY THNIEAVSCD EALVDITEIL AETKLTPDEF ANAVRMEIKD 
QTKCAASVGI GSNILLARMA TRKAKPDGQY HLKPEEVDDF IRGQLVTNLP GVGHSMESKL 
ASLGIKTCGD LQYMTMAKLQ KEFGPKTGQM LYRFCRGLDD RPVRTEKERK SVSAEINYGI 
RFTQPKEAEA FLLSLSEEIQ RRLEATGMKG KRLTLKIMVR KPGAPVETAK FGGHGICDNI 
ARTVTLDQAT DNAKIIGKAM LNMFHTMKLN ISDMRGVGIH VNQLVPTNLN PSTCPSRPSV 
QSSHFPSGSY SVRDVFQVQK AKKSTEEEHK EVFRAAVDLE ISSASRTCTF LPPFPAHLPT 
SPDTNKAESS GKWNGLHTPV SVQSRLNLSI EVPSPSQLDQ SVLEALPPDL REQVEQVCAV 
QQAESHGDKK KEPVNGCNTG ILPQPVGTVL LQIPEPQESN SDAGINLIAL PAFSQVDPEV 
FAALPAELQR ELKAAYDQRQ RQGENSTHQQ SASASVPKNP LLHLKAAVKE KKRNKKKKTI 
GSPKRIQSPL NNKLLNSPAK TLPGACGSPQ KLIDGFLKHE GPPAEKPLEE LSASTSGVPG 
LSSLQSDPAG CVRPPAPNLA GAVEFNDVKT LLREWITTIS DPMEEDILQV VKYCTDLIEE 
KDLEKLDLVI KYMKRLMQQS VESVWNMAFD FILDNVQVVL QQTYGSTLKV T

Genular Protein ID: 263124107

Symbol: Q49AI5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q49AI5

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 8 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PROSITE 4 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1 SUPFAM 3

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1114
  • Mass: 122366
  • Checksum: 588B0C5CF002CB47
  • Sequence:
    • MLHGGQYHVY YSRSKTTHII ATNLPNAKIK ELKGEKVIRP EWIVESIKAG RLLSYIPYQL 
YTKQSSVQKG LSFNPVCRPE DPLPGPSNIA KQLNNRVNHI VKKIETENEV KVNGMNSWNE 
EDENNDFSFV DLEQTSPGRK QNGIPHPRGS TAIFSGHTPS SNGALKTQDC LVPMVNSVAS 
RLSPAFSQEE DKAEKSSTDF RDCTLQQLQQ STRNTDALRN PHRTNSFSLS PLHSNTKING 
AHHSTVQGPS STKSTSSVST FSKAAPSVPS KPSDCNFISN FYSHSRLHHI SMWKCELTEF 
VNTLQRQSNG IFPGREKLKK MKTGRSALVV TDTGDMSVLN SPRHQSCIMH VDMDCFFVSV 
GIRNRPDLKG KPVAVTSNRG TGRAPLRPGA NPQLEWQYYQ NKILKGKADI PDSSLWENPD 
SAQANGIDSV LSRAEIASCS YEARQLGIKN GMFFGHAKQL CPNLQAVPYD FHAYKEVAQT 
LYETLASYTH NIEAVSCDEA LVDITEILAE TKLTPDEFAN AVRMEIKDQT KCAASVGIGS 
NILLARMATR KAKPDGQYHL KPEEVDDFIR GQLVTNLPGV GHSMESKLAS LGIKTCGDLQ 
YMTMAKLQKE FGPKTGQMLY RFCRGLDDRP VRTEKERKSV SAEINYGIRF TQPKEAEAFL 
LSLSEEIQRR LEATGMKGKR LTLKIMVRKP GAPVETAKFG GHGICDNIAR TVTLDQATDN 
AKIIGKAMLN MFHTMKLNIS DMRGVGTHVN QLVPTNLNPS TCPSRPSVQS SHFPSGSYSV 
RDVFQVQKAK KSTEEEHKEV FRAAVDLEIS SASRTCTFLP PFPAHLPTSP DTNKAESSGK 
WNGLHTPVSV QSRLNLSIEV PSPSQLDQSV LEALPPDLRE QVEQVCAVQQ AESHGDKKKE 
PVNGCNTGIL PQPVGTVLLQ IPEPQESNSD AGINLIALPA FSQVDPEVFA ALPAELQREL 
KAAYDQRQRQ GENSTHQQSA SASVPKNPLL HLKAAVKEKK RNKKKKTIGS PKRIQSPLNN 
KLLNSPAKTL PGACGSPQKL IDGFLKHEGP PAEKPLEELS ASTSGVPGLS SLQSDPAGCV 
RPPAPNLAGA VEFNDVKTLL REWITTISGW LGLC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.