Details for: PDE1B

Gene ID: 5153

Symbol: PDE1B

Ensembl ID: ENSG00000123360

Description: phosphodiesterase 1B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 50.4676
    Cell Significance Index: -7.8500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 29.5296
    Cell Significance Index: -7.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 6.3830
    Cell Significance Index: -7.8700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 4.5236
    Cell Significance Index: 99.0500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.7375
    Cell Significance Index: 165.3200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.4914
    Cell Significance Index: 132.2100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.9995
    Cell Significance Index: -7.8900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.5901
    Cell Significance Index: -3.4800
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.3072
    Cell Significance Index: 10.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0045
    Cell Significance Index: 201.5100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.9494
    Cell Significance Index: 58.2100
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 0.9064
    Cell Significance Index: 7.8400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5523
    Cell Significance Index: 198.1100
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 0.5184
    Cell Significance Index: 5.9700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.4745
    Cell Significance Index: 6.3300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4680
    Cell Significance Index: 10.1400
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.4311
    Cell Significance Index: 6.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3929
    Cell Significance Index: 26.4200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3572
    Cell Significance Index: 16.1900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2743
    Cell Significance Index: 52.2100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1868
    Cell Significance Index: 9.8100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1667
    Cell Significance Index: 16.4900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1524
    Cell Significance Index: 137.6200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1385
    Cell Significance Index: 16.1400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1305
    Cell Significance Index: 8.0200
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.0998
    Cell Significance Index: 0.9500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0981
    Cell Significance Index: 0.8000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0938
    Cell Significance Index: 2.2500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0875
    Cell Significance Index: 2.3400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0820
    Cell Significance Index: 13.3400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0615
    Cell Significance Index: 1.9700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0509
    Cell Significance Index: 5.5400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0382
    Cell Significance Index: 16.8700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0198
    Cell Significance Index: 0.2500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0156
    Cell Significance Index: 0.4000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0095
    Cell Significance Index: 0.6600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0020
    Cell Significance Index: 0.0700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0026
    Cell Significance Index: -4.9300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0037
    Cell Significance Index: -6.8300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0044
    Cell Significance Index: -0.1100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0044
    Cell Significance Index: -6.7600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0051
    Cell Significance Index: -6.9000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0080
    Cell Significance Index: -5.8700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0090
    Cell Significance Index: -5.7400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0091
    Cell Significance Index: -1.8100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0095
    Cell Significance Index: -7.0500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0101
    Cell Significance Index: -7.6800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0111
    Cell Significance Index: -0.2400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0118
    Cell Significance Index: -6.6500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0119
    Cell Significance Index: -5.4200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0130
    Cell Significance Index: -7.1000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0135
    Cell Significance Index: -0.8100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0193
    Cell Significance Index: -0.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0201
    Cell Significance Index: -5.7900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0257
    Cell Significance Index: -4.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0261
    Cell Significance Index: -3.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0302
    Cell Significance Index: -3.0900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0306
    Cell Significance Index: -4.2000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0314
    Cell Significance Index: -2.2200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0325
    Cell Significance Index: -4.7200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0335
    Cell Significance Index: -0.4800
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.0345
    Cell Significance Index: -0.1500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0349
    Cell Significance Index: -0.7000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0353
    Cell Significance Index: -2.2800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0386
    Cell Significance Index: -8.1400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0455
    Cell Significance Index: -5.8300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0458
    Cell Significance Index: -1.4600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0460
    Cell Significance Index: -5.6600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0460
    Cell Significance Index: -7.8500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0461
    Cell Significance Index: -1.5100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0499
    Cell Significance Index: -6.4500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0525
    Cell Significance Index: -0.9700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0643
    Cell Significance Index: -0.7000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0648
    Cell Significance Index: -1.3800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0683
    Cell Significance Index: -1.3500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0687
    Cell Significance Index: -7.8700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0744
    Cell Significance Index: -7.7500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0787
    Cell Significance Index: -6.2400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0837
    Cell Significance Index: -2.4000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0839
    Cell Significance Index: -6.4400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0880
    Cell Significance Index: -6.5600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0886
    Cell Significance Index: -2.3300
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0900
    Cell Significance Index: -1.2000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0921
    Cell Significance Index: -4.3300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0921
    Cell Significance Index: -5.1700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0925
    Cell Significance Index: -5.8300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0968
    Cell Significance Index: -2.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0997
    Cell Significance Index: -5.1800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.1058
    Cell Significance Index: -1.4900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1142
    Cell Significance Index: -2.3700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1170
    Cell Significance Index: -3.2700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1171
    Cell Significance Index: -3.4400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1198
    Cell Significance Index: -2.0100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1233
    Cell Significance Index: -2.6400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1253
    Cell Significance Index: -4.3900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1307
    Cell Significance Index: -2.2400
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.1319
    Cell Significance Index: -1.7100
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.1319
    Cell Significance Index: -1.4600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1342
    Cell Significance Index: -2.6200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PDE1B is a dual specificity phosphodiesterase, capable of hydrolyzing both cAMP and cGMP. This unique property allows PDE1B to modulate multiple signaling pathways, including those mediated by calmodulin, a calcium-binding protein. The enzyme is highly specific for its substrates, with a high affinity for cGMP and a lower affinity for cAMP. PDE1B is also sensitive to calcium-dependent events, which regulate its activity and interact with calmodulin. **Pathways and Functions:** PDE1B plays a crucial role in various signaling pathways, including: 1. **Calmodulin-activated pathways:** PDE1B is activated by calmodulin, leading to the hydrolysis of cGMP and modulating calcium-dependent events, such as muscle contraction and neurotransmitter release. 2. **G-protein coupled receptor (GPCR) signaling:** PDE1B regulates the activity of GPCRs, influencing responses to hormones, neurotransmitters, and other extracellular ligands. 3. **Intracellular signaling by second messengers:** PDE1B modulates the levels of cAMP and cGMP, influencing cellular responses to various stimuli, including growth factors, cytokines, and neurotransmitters. 4. **Neuronal function:** PDE1B is expressed in the brain, where it regulates neurotransmitter release, synaptic plasticity, and neuronal excitability. **Clinical Significance:** PDE1B has been implicated in various diseases and disorders, including: 1. **Immune system disorders:** PDE1B is involved in the regulation of immune responses, including the activation of immune cells, such as T cells and macrophages. 2. **Neurological disorders:** PDE1B has been linked to neurodegenerative diseases, such as Alzheimer's and Parkinson's, where it regulates neurotransmitter release and synaptic plasticity. 3. **Cancer:** PDE1B has been implicated in cancer progression, where it modulates cell growth, survival, and metastasis. 4. **Hemostasis and cardiovascular disease:** PDE1B regulates platelet function, influencing blood clotting and cardiovascular disease. **Significantly Expressed Cells:** PDE1B is expressed in various cell types, including: 1. **Immune cells:** PDE1B is expressed in T cells, macrophages, and other immune cells, where it regulates immune responses. 2. **Neuronal cells:** PDE1B is expressed in neurons, where it regulates neurotransmitter release and synaptic plasticity. 3. **Epithelial cells:** PDE1B is expressed in epithelial cells, where it regulates cell growth and differentiation. In conclusion, PDE1B is a multifunctional enzyme that plays a crucial role in various cellular processes, including immune responses, neuronal function, and disease. Further research is needed to fully elucidate the mechanisms of PDE1B and its clinical significance, but this review provides a comprehensive overview of its key characteristics, pathways, and functions.

Genular Protein ID: 3174091081

Symbol: PDE1B_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q01064 Q92825 Q96KP3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 19 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 7 DrugCentral 1 EC 1 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 3 RefSeq 6 Rhea 6 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8855339

Title: Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells.

PubMed ID: 8855339

DOI: 10.1073/pnas.93.20.11236

PubMed ID: 9419816

Title: Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1.

PubMed ID: 9419816

DOI: 10.1016/s0898-6568(97)00046-6

PubMed ID: 11747989

Title: Isolation and differential tissue distribution of two human cDNAs encoding PDE1 splice variants.

PubMed ID: 11747989

DOI: 10.1016/s0898-6568(01)00207-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1326532

Title: A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase.

PubMed ID: 1326532

DOI: 10.1016/s0021-9258(19)37015-2

PubMed ID: 15260978

Title: A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases.

PubMed ID: 15260978

DOI: 10.1016/j.molcel.2004.07.005

Sequence Information:

  • Length: 536
  • Mass: 61380
  • Checksum: D15211AC32C756A4
  • Sequence:
    • MELSPRSPPE MLEESDCPSP LELKSAPSKK MWIKLRSLLR YMVKQLENGE INIEELKKNL 
EYTASLLEAV YIDETRQILD TEDELQELRS DAVPSEVRDW LASTFTQQAR AKGRRAEEKP 
KFRSIVHAVQ AGIFVERMFR RTYTSVGPTY STAVLNCLKN LDLWCFDVFS LNQAADDHAL 
RTIVFELLTR HNLISRFKIP TVFLMSFLDA LETGYGKYKN PYHNQIHAAD VTQTVHCFLL 
RTGMVHCLSE IELLAIIFAA AIHDYEHTGT TNSFHIQTKS ECAIVYNDRS VLENHHISSV 
FRLMQDDEMN IFINLTKDEF VELRALVIEM VLATDMSCHF QQVKTMKTAL QQLERIDKPK 
ALSLLLHAAD ISHPTKQWLV HSRWTKALME EFFRQGDKEA ELGLPFSPLC DRTSTLVAQS 
QIGFIDFIVE PTFSVLTDVA EKSVQPLADE DSKSKNQPSF QWRQPSLDVE VGDPNPDVVS 
FRSTWVKRIQ ENKQKWKERA ASGITNQMSI DELSPCEEEA PPSPAEDEHN QNGNLD

Genular Protein ID: 2465564753

Symbol: Q7Z364_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z364

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 DNASU 1 DisGeNET 1 EMBL 4 GO 5 Gene3D 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 5 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 399
  • Mass: 45551
  • Checksum: AB998833C5B04B12
  • Sequence:
    • MFRRTYTSVG PTYSTAVLNC LKNLDLWCFD VFSLNQAADD HALRTIVFEL LTRHNLISRF 
KIPTVFLMSF LDALETGYGK YKNPYHNQIH AADVTQTVHC FLLRTGMVHC LSEIELLAII 
FAAAIHDYEH TGTTNSFHIQ TKSECAIVYN DRSVLENHHI SSVFRLMQDD EMNIFINLTK 
DEFVELRALV IEMVLATDMS CHFQQVKTMK TALQQLERID KPKALSLLLH AADISHPTKQ 
WLVHSRWTKA LMEEFFRQGD KEAELGLPFS PLCDRTSTLV AQSQIGFIDF IVEPTFSVLT 
DVAEKSVQPL ADEDSKSKNQ PSFQWRQPSL DVEVGDPNPD VVSFRSTWVK RIQENKQKWK 
ERAASGITNQ MSIDELSPCE EEAPPSPAED EHNQNGNLD

Genular Protein ID: 2121415124

Symbol: B3KX78_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KX78

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 332
  • Mass: 37774
  • Checksum: CE99DF518D506D5C
  • Sequence:
    • MSFLDALETG YGKYKNPYHN QIHAADVTQT VHCFLLRTGM VHCLSEIELL AIIFAAAIHD 
YEHTGTTNSF HIQTKSECAI VYNDRSVLEN HHISSVFRLM QDDEMNIFIN LTKDEFVELR 
ALVIEMVLAT DMSCHFQQVK TMKTALQQLE RIDKPKALSL LLHAADISHP TKQWLVHSRW 
TKALMEEFFR QGDKEAELGL PFSPLCDRTS TLVAQSQIGF IDFIVEPTFS VLTDVAEKSV 
QPLADEDSKS KNQPSFQWRQ PSLDVEVGDP NPDVVSFRST WVKRIQENKQ KWKERAASGI 
TNQMSIDELS PCEEEAPPSP AEDEHNQNGN LD

Genular Protein ID: 2178713015

Symbol: B4DK72_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DK72

Database IDs:

ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 24 DNASU 1 DisGeNET 1 EC 1 EMBL 4 Ensembl 2 GO 4 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 6 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 2 Rhea 6 RuleBase 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

Sequence Information:

  • Length: 495
  • Mass: 56623
  • Checksum: EEF080C3D3CAF196
  • Sequence:
    • MVKQLENGEI NIEELKKNLE YTASLLEAVY IDETRQILDT EDELQELRSD AVPSEVRDWL 
ASTFTQQARA KGRRAEEKPK FRSIVHAVQA GIFVERMFRR TYTSVGPTYS TAVLNCLKNL 
DLWCFDVFSL NQAADDHALR TIVFELLTRH NLISRFKIPT VFLMSFLDAL ETGYGKYKNP 
YHNQIHAADV TQTVHCFLLR TGMVHCLSEI ELLAIIFAAA IHDYEHTGTT NSFHIQTKSE 
CAIVYNDRSV LENHHISSVF RLMQDDEMNI FINLTKDEFV ELRALVIEMV LATDMSCHFQ 
QVKTMKTALQ QLERIDKPKA LSLLLHAADI SHPTKQWLVH SRWTKALMEE FFRQGDKEAE 
LGLPFSPLCD RTSTLVAQSQ IGFIDFIVEP TFSVLTDVAE KSVQPLADED SKSKNQPSFQ 
WRQPSLDVEV GDPNPDVVSF RSTWVKRIQE NKQKWKERAA SGITNQMSID ELSPCEEEAP 
PSPAEDEHNQ NGNLD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.