Details for: PKNOX1

Gene ID: 5316

Symbol: PKNOX1

Ensembl ID: ENSG00000160199

Description: PBX/knotted 1 homeobox 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 186.8267
    Cell Significance Index: -29.0600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 116.1079
    Cell Significance Index: -29.4500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 78.4080
    Cell Significance Index: -32.3000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 66.5505
    Cell Significance Index: -31.4200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 64.6881
    Cell Significance Index: -26.2800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 58.0499
    Cell Significance Index: -29.8600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.5833
    Cell Significance Index: -26.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 25.0861
    Cell Significance Index: -30.9300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.8554
    Cell Significance Index: -29.0800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.5269
    Cell Significance Index: -26.1900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.8864
    Cell Significance Index: -31.1200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5621
    Cell Significance Index: 313.3500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.3839
    Cell Significance Index: 37.6700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.3186
    Cell Significance Index: 17.9900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.1948
    Cell Significance Index: 826.3600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1443
    Cell Significance Index: 227.0900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0239
    Cell Significance Index: 101.2900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9883
    Cell Significance Index: 354.4800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.8825
    Cell Significance Index: 49.5200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7167
    Cell Significance Index: 31.7000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6935
    Cell Significance Index: 26.2600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5791
    Cell Significance Index: 94.1800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5456
    Cell Significance Index: 59.3400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5276
    Cell Significance Index: 11.4300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4640
    Cell Significance Index: 63.7200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4535
    Cell Significance Index: 20.5600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4356
    Cell Significance Index: 26.1500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4222
    Cell Significance Index: 12.1700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3954
    Cell Significance Index: 215.9600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2999
    Cell Significance Index: 54.0600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2964
    Cell Significance Index: 22.7500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2874
    Cell Significance Index: 35.3400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2748
    Cell Significance Index: 7.6800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.2204
    Cell Significance Index: 6.2900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2183
    Cell Significance Index: 15.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1882
    Cell Significance Index: 11.5700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1826
    Cell Significance Index: 12.2800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1700
    Cell Significance Index: 153.4700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1552
    Cell Significance Index: 29.5400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1068
    Cell Significance Index: 3.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0970
    Cell Significance Index: 6.2600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0889
    Cell Significance Index: 39.3100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0759
    Cell Significance Index: 1.3000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0755
    Cell Significance Index: 142.2100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0709
    Cell Significance Index: 8.3600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0633
    Cell Significance Index: 2.2300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0509
    Cell Significance Index: 2.3900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0501
    Cell Significance Index: 77.0900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0500
    Cell Significance Index: 1.2500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0453
    Cell Significance Index: 28.7500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0270
    Cell Significance Index: 1.4000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0263
    Cell Significance Index: 48.5500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0056
    Cell Significance Index: 0.1500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0019
    Cell Significance Index: 0.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0018
    Cell Significance Index: 2.4900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0002
    Cell Significance Index: 0.0100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0053
    Cell Significance Index: -0.6800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0127
    Cell Significance Index: -1.6500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0263
    Cell Significance Index: -19.3000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0324
    Cell Significance Index: -24.4900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0349
    Cell Significance Index: -0.7500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0377
    Cell Significance Index: -27.9300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0532
    Cell Significance Index: -1.4300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0535
    Cell Significance Index: -30.1900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0586
    Cell Significance Index: -36.6000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0916
    Cell Significance Index: -26.3700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0925
    Cell Significance Index: -9.4500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1061
    Cell Significance Index: -7.9100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1122
    Cell Significance Index: -13.0800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1156
    Cell Significance Index: -16.8100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1212
    Cell Significance Index: -20.7000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1443
    Cell Significance Index: -2.4200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1545
    Cell Significance Index: -3.2900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1693
    Cell Significance Index: -35.6700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1732
    Cell Significance Index: -4.9700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1781
    Cell Significance Index: -20.4100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1968
    Cell Significance Index: -4.7200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2113
    Cell Significance Index: -13.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2221
    Cell Significance Index: -11.6600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2323
    Cell Significance Index: -24.1900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.2485
    Cell Significance Index: -3.3200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2507
    Cell Significance Index: -17.7300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2631
    Cell Significance Index: -5.7600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2820
    Cell Significance Index: -7.2500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3181
    Cell Significance Index: -16.5700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3285
    Cell Significance Index: -20.1400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3423
    Cell Significance Index: -27.1100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3887
    Cell Significance Index: -8.2500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4078
    Cell Significance Index: -13.0600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4503
    Cell Significance Index: -14.3400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4658
    Cell Significance Index: -15.2500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5005
    Cell Significance Index: -13.1600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.5513
    Cell Significance Index: -7.9000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5747
    Cell Significance Index: -12.0300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5750
    Cell Significance Index: -11.3700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5843
    Cell Significance Index: -11.7300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6239
    Cell Significance Index: -21.8600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6317
    Cell Significance Index: -18.6100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.6498
    Cell Significance Index: -16.2100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.6868
    Cell Significance Index: -13.4100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PKNOX1 belongs to the PBX/knotted homeobox family, which is a group of transcription factors known for their role in developmental biology and cell differentiation. This gene exhibits a high degree of specificity in its expression, with notable presence in near-projecting glutamatergic cortical neurons, L2/3-6 intratelencephalic projecting glutamatergic neurons, vip GABAergic cortical interneurons, and other cell types. The gene's expression is also observed in germ cells, dopaminergic neurons, and astrocytes of the cerebral cortex, underscoring its role in neural development and tissue formation. **Pathways and Functions** PKNOX1 is involved in several key pathways, including: 1. **Anterior Hox Gene Activation**: PKNOX1 regulates the expression of anterior Hox genes during hindbrain development during early embryogenesis, which is crucial for the proper formation of the brain and nervous system. 2. **Angiogenesis**: PKNOX1 is involved in angiogenesis, the process of new blood vessel formation, which is essential for tissue development and growth. 3. **Camera-type Eye Development**: PKNOX1 plays a role in the development of camera-type eyes, a type of eye found in cephalopods and other animals. 4. **Transcriptional Regulation**: As a transcription factor, PKNOX1 regulates the expression of target genes by binding to specific DNA sequences and interacting with RNA polymerase II. **Clinical Significance** While PKNOX1 is not a well-studied gene, its involvement in neural development and tissue formation suggests potential implications for neurological disorders. For example: 1. **Neurodevelopmental Disorders**: Mutations in PKNOX1 may contribute to neurodevelopmental disorders such as autism spectrum disorder, schizophrenia, or other cognitive impairments. 2. **Cancer**: PKNOX1's role in cellular differentiation and proliferation may also be relevant to cancer research, particularly in the context of neural tumors. 3. **Regenerative Medicine**: Understanding PKNOX1's functions may provide insights into the development of therapeutic strategies for tissue repair and regeneration. In conclusion, PKNOX1 is a transcription factor that plays a critical role in various developmental processes and cellular functions. Its expression in specific cell types and involvement in key pathways highlight its importance in neural development and tissue formation. Further research is needed to elucidate the clinical significance of PKNOX1 and its potential applications in neurological disorders and cancer.

Genular Protein ID: 1203806922

Symbol: PKNX1_HUMAN

Name: Homeobox protein PKNOX1

UniProtKB Accession Codes:

P55347 O00528 Q8IWT7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9143494

Title: Cloning of a novel homeobox-containing gene, PKNOX1, and mapping to human chromosome 21q22.3.

PubMed ID: 9143494

DOI: 10.1006/geno.1997.4632

PubMed ID: 9479508

Title: PKNOX1, a gene encoding PREP1, a new regulator of Pbx activity, maps on human chromosome 21q22.3 and murine chromosome 17B/C.

PubMed ID: 9479508

DOI: 10.1006/geno.1997.5086

PubMed ID: 15468914

Title: Molecular cloning for an alternatively splicing cDNA of human PKNOX1 gene and it's expression analysis.

PubMed ID: 15468914

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 31839203

Title: Gain-of-function MN1 truncation variants cause a recognizable syndrome with craniofacial and brain abnormalities.

PubMed ID: 31839203

DOI: 10.1016/j.ajhg.2019.11.011

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 436
  • Mass: 47607
  • Checksum: 381E901F435AC5F2
  • Sequence:
    • MMATQTLSID SYQDGQQMQV VTELKTEQDP NCSEPDAEGV SPPPVESQTP MDVDKQAIYR 
HPLFPLLALL FEKCEQSTQG SEGTTSASFD VDIENFVRKQ EKEGKPFFCE DPETDNLMVK 
AIQVLRIHLL ELEKVNELCK DFCSRYIACL KTKMNSETLL SGEPGSPYSP VQSQQIQSAI 
TGTISPQGIV VPASALQQGN VAMATVAGGT VYQPVTVVTP QGQVVTQTLS PGTIRIQNSQ 
LQLQLNQDLS ILHQDDGSSK NKRGVLPKHA TNVMRSWLFQ HIGHPYPTED EKKQIAAQTN 
LTLLQVNNWF INARRRILQP MLDSSCSETP KTKKKTAQNR PVQRFWPDSI ASGVAQPPPS 
ELTMSEGAVV TITTPVNMNV DSLQSLSSDG ATLAVQQVMM AGQSEDESVD STEEDAGALA 
PAHISGLVLE NSDSLQ

Genular Protein ID: 3255815686

Symbol: E7EPN6_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EPN6

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 319
  • Mass: 34519
  • Checksum: D0D47039D1B45670
  • Sequence:
    • MVKAIQVLRI HLLELEKVNE LCKDFCSRYI ACLKTKMNSE TLLSGEPGSP YSPVQSQQIQ 
SAITGTISPQ GIVVPASALQ QGNVAMATVA GGTVYQPVTV VTPQGQVVTQ TLSPGTIRIQ 
NSQLQLQLNQ DLSILHQDDG SSKNKRGVLP KHATNVMRSW LFQHIGHPYP TEDEKKQIAA 
QTNLTLLQVN NWFINARRRI LQPMLDSSCS ETPKTKKKTA QNRPVQRFWP DSIASGVAQP 
PPSELTMSEG AVVTITTPVN MNVDSLQSLS SDGATLAVQQ VMMAGQSEDE SVDSTEEDAG 
ALAPAHISGL VLENSDSLQ

Genular Protein ID: 1512031010

Symbol: B4DGV5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DGV5

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 319
  • Mass: 34547
  • Checksum: 54463854676F3B36
  • Sequence:
    • MVKAIQVLRI HLLELEKVNE LCKDFCSRYI ACLKTKMNSE TLLSGEPGSP YSPVQSQQIQ 
SAITGTISPQ GIVVPASALQ RGNVAMATVA GGTVYQPVTV VTPQGQVVTQ TLSPGTIRIQ 
NSQLQLQLNQ DLSILHQDDG SSKNKRGVLP KHATNVMRSW LFQHIGHPYP TEDEKKQIAA 
QTNLTLLQVN NWFINARRRI LQPMLDSSCS ETPKTKKKTA QNRPVQRFWP DSIASGVAQP 
PPSELTMSEG AVVTITTPVN MNVDSLQSLS SDGATLAVQQ VMMAGQSEDE SVDSTEEDAG 
ALAPAHISGL VLENSDSLQ

Genular Protein ID: 2663857688

Symbol: Q6PKH2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PKH2

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 336
  • Mass: 37296
  • Checksum: 7CDB474D4C3A455B
  • Sequence:
    • MMATQTLSID SYQDGQQMQV VTELKTEQDP NCSEPDAEGV SPPPVESQTP MDVDKQAIYR 
HPLFPLLALL FEKCEQSTQG SEGTTSASFD VDIENFVRKQ EKEGKPFFCE DPETDNLMVK 
AIQVLRIHLL ELEKVNELCK DFCSRYIACL KTKMNSETLL SGEPGSPYSP VQSQQIQSAI 
TGTISPQGIV VPASALQQGN VAMATVAGGT VYQPVTVVTP QGQVVTQTLS PGTIRIQNSQ 
LQLQLNQDLS ILHQDDGSSK NKRGVLPKHA TNVMRSWLFQ HIGHPYPTED EKKQIAAQTN 
LTLLQVNNWF INARRRILQP MLDSSCSETP KKKKKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.