Details for: PLAGL1

Gene ID: 5325

Symbol: PLAGL1

Ensembl ID: ENSG00000118495

Description: PLAG1 like zinc finger 1

Associated with

  • Gene expression (transcription)
    (R-HSA-74160)
  • Generic transcription pathway
    (R-HSA-212436)
  • Rna polymerase ii transcription
    (R-HSA-73857)
  • Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
    (R-HSA-6804115)
  • Tp53 regulates transcription of cell cycle genes
    (R-HSA-6791312)
  • Transcriptional regulation by tp53
    (R-HSA-3700989)
  • Apoptotic process
    (GO:0006915)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Golgi apparatus
    (GO:0005794)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Metal ion binding
    (GO:0046872)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nuclear body
    (GO:0016604)
  • Nucleoplasm
    (GO:0005654)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of cell cycle
    (GO:0051726)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 220.3539
    Cell Significance Index: -34.2800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 107.8680
    Cell Significance Index: -27.3600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 92.9002
    Cell Significance Index: -38.2700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 76.2937
    Cell Significance Index: -36.0200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 72.1957
    Cell Significance Index: -29.3300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 53.7538
    Cell Significance Index: -36.0700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 30.8669
    Cell Significance Index: -29.4700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.1235
    Cell Significance Index: -34.6800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.9533
    Cell Significance Index: -34.7000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.0711
    Cell Significance Index: -24.2300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 10.2751
    Cell Significance Index: 275.3300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.8886
    Cell Significance Index: -35.0800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 5.5569
    Cell Significance Index: 71.1700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 5.1211
    Cell Significance Index: 99.9500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.3880
    Cell Significance Index: 16.1800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.5257
    Cell Significance Index: 21.9100
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: 1.2626
    Cell Significance Index: 6.0400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.2440
    Cell Significance Index: 35.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.2396
    Cell Significance Index: 170.2300
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.2058
    Cell Significance Index: 7.4600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.1612
    Cell Significance Index: 126.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1560
    Cell Significance Index: 231.8900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.0252
    Cell Significance Index: 61.5500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7054
    Cell Significance Index: 114.7200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.6856
    Cell Significance Index: 9.8600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6698
    Cell Significance Index: 34.8900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6192
    Cell Significance Index: 28.0700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4557
    Cell Significance Index: 90.4300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4536
    Cell Significance Index: 409.5900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.4535
    Cell Significance Index: 2.7400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4361
    Cell Significance Index: 301.6000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3450
    Cell Significance Index: 23.2000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.3446
    Cell Significance Index: 17.4200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.3265
    Cell Significance Index: 3.5500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3133
    Cell Significance Index: 8.7600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2976
    Cell Significance Index: 162.5400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2563
    Cell Significance Index: 91.9300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2084
    Cell Significance Index: 6.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1934
    Cell Significance Index: 9.0900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1925
    Cell Significance Index: 85.0900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1525
    Cell Significance Index: 4.0100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1324
    Cell Significance Index: 13.1000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1228
    Cell Significance Index: 23.3700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1220
    Cell Significance Index: 9.3600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1195
    Cell Significance Index: 2.5900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1169
    Cell Significance Index: 74.2800
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.1128
    Cell Significance Index: 1.4200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1092
    Cell Significance Index: 49.5800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1032
    Cell Significance Index: 7.3000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0939
    Cell Significance Index: 1.4900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0610
    Cell Significance Index: 93.9500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0539
    Cell Significance Index: 3.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0495
    Cell Significance Index: 93.2200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0469
    Cell Significance Index: 86.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0423
    Cell Significance Index: 7.2200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0397
    Cell Significance Index: 0.6700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0201
    Cell Significance Index: 3.6300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0183
    Cell Significance Index: 2.2500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0165
    Cell Significance Index: 0.5800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0043
    Cell Significance Index: 0.0900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0058
    Cell Significance Index: -0.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0063
    Cell Significance Index: -8.5700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0144
    Cell Significance Index: -10.6600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0176
    Cell Significance Index: -13.3500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0187
    Cell Significance Index: -11.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0195
    Cell Significance Index: -2.5300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0236
    Cell Significance Index: -17.3300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0282
    Cell Significance Index: -15.9000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0481
    Cell Significance Index: -1.5400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0514
    Cell Significance Index: -0.7700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0516
    Cell Significance Index: -6.6100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0554
    Cell Significance Index: -1.1800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0940
    Cell Significance Index: -5.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0941
    Cell Significance Index: -19.8100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0979
    Cell Significance Index: -2.6700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0990
    Cell Significance Index: -28.4900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1006
    Cell Significance Index: -3.8100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1034
    Cell Significance Index: -12.0500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1450
    Cell Significance Index: -17.1000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1902
    Cell Significance Index: -6.6100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2014
    Cell Significance Index: -8.9100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2022
    Cell Significance Index: -20.6500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2184
    Cell Significance Index: -4.5300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2204
    Cell Significance Index: -25.1600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2243
    Cell Significance Index: -10.4600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2258
    Cell Significance Index: -25.8700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2323
    Cell Significance Index: -4.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2357
    Cell Significance Index: -24.5400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2517
    Cell Significance Index: -6.4300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2644
    Cell Significance Index: -2.7400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3138
    Cell Significance Index: -23.3900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3420
    Cell Significance Index: -9.7600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3648
    Cell Significance Index: -23.5400
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3716
    Cell Significance Index: -3.0300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3898
    Cell Significance Index: -30.8700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4175
    Cell Significance Index: -25.6000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4658
    Cell Significance Index: -24.4600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4771
    Cell Significance Index: -6.5100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4826
    Cell Significance Index: -12.9100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4929
    Cell Significance Index: -13.1600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Zinc Finger Domain**: PLAGL1 contains a characteristic zinc finger domain, which is essential for its DNA-binding capabilities. This domain allows PLAGL1 to interact with specific DNA sequences, thereby regulating gene expression. 2. **Transcriptional Regulation**: PLAGL1 exhibits both activator and repressor activities, influencing the expression of various genes. Its ability to regulate transcriptional processes makes it a crucial regulator of cellular homeostasis. 3. **Cell Type-Specific Expression**: PLAGL1 is expressed in specific cell types, including cortical cells of the adrenal gland, endocrine cells, and interstitial cells of the ovary. This cell-type specificity suggests that PLAGL1 plays distinct roles in various tissues. 4. **Interactions with Other Proteins**: PLAGL1 interacts with other proteins, including TP53, a tumor suppressor protein, and RNA polymerase II, a key enzyme in transcriptional regulation. **Pathways and Functions** 1. **Apoptotic Process**: PLAGL1 has been implicated in the regulation of apoptosis, a process essential for maintaining tissue homeostasis. Its ability to modulate the expression of pro-apoptotic genes makes it a critical regulator of cell death. 2. **Gene Expression (Transcription)**: PLAGL1 regulates gene expression by interacting with specific DNA sequences, thereby influencing the transcriptional activity of RNA polymerase II. 3. **Regulation of Cell Cycle**: PLAGL1 plays a role in regulating the cell cycle, influencing the expression of genes involved in cell proliferation and differentiation. 4. **Transcriptional Regulation by TP53**: PLAGL1 interacts with TP53, a tumor suppressor protein, to regulate the expression of cell cycle genes. This interaction highlights the importance of PLAGL1 in maintaining genomic stability. **Clinical Significance** 1. **Cancer Association**: Alterations in PLAGL1 expression have been observed in various cancers, including breast, ovarian, and prostate cancer. These alterations suggest that PLAGL1 may play a role in tumorigenesis. 2. **Neurological Disorders**: PLAGL1 has been implicated in neurological disorders, including autism spectrum disorder and schizophrenia. Its role in regulating gene expression and cell signaling pathways makes it a potential therapeutic target for these conditions. 3. **Endocrine Disorders**: PLAGL1 is expressed in endocrine cells, and alterations in its expression may contribute to endocrine disorders, such as adrenal insufficiency. In conclusion, PLAGL1 is a multifunctional gene that regulates various cellular processes, including transcription, apoptosis, and cell cycle. Its interactions with other proteins, including TP53 and RNA polymerase II, highlight its importance in maintaining genomic stability and tissue homeostasis. Further research is necessary to fully elucidate the role of PLAGL1 in disease and to explore its potential as a therapeutic target.

Genular Protein ID: 499027647

Symbol: PLAL1_HUMAN

Name: Zinc finger protein PLAGL1

UniProtKB Accession Codes:

Q9UM63 B2RBA4 B2RCM8 E1P595 E1P597 O76019 Q7Z3V8 Q92981 Q96JR9 Q9UIZ0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 17 Ensembl 14 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 27 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9150364

Title: Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors.

PubMed ID: 9150364

DOI: 10.1038/sj.onc.1201034

PubMed ID: 9722527

Title: Transcriptional activation capacity of the novel PLAG family of zinc finger proteins.

PubMed ID: 9722527

DOI: 10.1074/jbc.273.36.23026

PubMed ID: 9671765

Title: hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer.

PubMed ID: 9671765

DOI: 10.1073/pnas.95.15.8835

PubMed ID: 11313869

Title: Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities.

PubMed ID: 11313869

DOI: 10.1038/sj.onc.1204237

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11935319

Title: Relaxation of imprinted expression of ZAC and HYMAI in a patient with transient neonatal diabetes mellitus.

PubMed ID: 11935319

DOI: 10.1007/s00439-001-0671-5

PubMed ID: 18299245

Title: Human Spot 14 protein is a p53-dependent transcriptional coactivator via the recruitment of thyroid receptor and Zac1.

PubMed ID: 18299245

DOI: 10.1016/j.biocel.2008.01.014

PubMed ID: 18622393

Title: Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57.

PubMed ID: 18622393

DOI: 10.1038/ng.187

Sequence Information:

  • Length: 463
  • Mass: 50819
  • Checksum: B10C74DA409BD4F7
  • Sequence:
    • MATFPCQLCG KTFLTLEKFT IHNYSHSRER PYKCVQPDCG KAFVSRYKLM RHMATHSPQK 
SHQCAHCEKT FNRKDHLKNH LQTHDPNKMA FGCEECGKKY NTMLGYKRHL ALHAASSGDL 
TCGVCALELG STEVLLDHLK AHAEEKPPSG TKEKKHQCDH CERCFYTRKD VRRHLVVHTG 
CKDFLCQFCA QRFGRKDHLT RHTKKTHSQE LMKESLQTGD LLSTFHTISP SFQLKAAALP 
PFPLGASAQN GLASSLPAEV HSLTLSPPEQ AAQPMQPLPE SLASLHPSVS PGSPPPPLPN 
HKYNTTSTSY SPLASLPLKA DTKGFCNISL FEDLPLQEPQ SPQKLNPGFD LAKGNAGKVN 
LPKELPADAV NLTIPASLDL SPLLGFWQLP PPATQNTFGN STLALGPGES LPHRLSCLGQ 
QQQEPPLAMG TVSLGQLPLP PIPHVFSAGT GSAILPHFHH AFR

Genular Protein ID: 3969392955

Symbol: A1YLA1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A1YLA1

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Proteomes 2 RefSeq 13 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17341487

Title: Tissue-specific imprinting of the ZAC/PLAGL1 tumour suppressor gene results from variable utilization of monoallelic and biallelic promoters.

PubMed ID: 17341487

DOI: 10.1093/hmg/ddm041

Sequence Information:

  • Length: 64
  • Mass: 7506
  • Checksum: 9B6414824E8204E9
  • Sequence:
    • MATFPCQLCG KTFLTLEKFT IHNYSHSRER PYKCVQPDCG KAFVSRYKLM RHMATHSPQK 
SHQC

Genular Protein ID: 3970152708

Symbol: A1YLA2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A1YLA2

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 28 Ensembl 2 GeneTree 1 HGNC 1 NCBI Taxonomy 1 OrthoDB 1 Proteomes 2 RefSeq 5 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17341487

Title: Tissue-specific imprinting of the ZAC/PLAGL1 tumour suppressor gene results from variable utilization of monoallelic and biallelic promoters.

PubMed ID: 17341487

DOI: 10.1093/hmg/ddm041

PubMed ID: 28957425

Title: A tissue-specific promoter derived from a SINE retrotransposon drives biallelic expression of PLAGL1 in human lymphocytes.

PubMed ID: 28957425

Sequence Information:

  • Length: 12
  • Mass: 1355
  • Checksum: 9A8E85AF8A26C775
  • Sequence:
    • MATHSPQKSH QC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.