Details for: PLS3

Gene ID: 5358

Symbol: PLS3

Ensembl ID: ENSG00000102024

Description: plastin 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 332.5399
    Cell Significance Index: -51.7300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 201.5428
    Cell Significance Index: -51.1200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 138.9254
    Cell Significance Index: -57.2300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 111.0305
    Cell Significance Index: -52.4200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 108.0843
    Cell Significance Index: -43.9100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 45.9548
    Cell Significance Index: -43.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 42.0615
    Cell Significance Index: -51.8600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.6167
    Cell Significance Index: -31.9900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.1042
    Cell Significance Index: -51.7100
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 5.4862
    Cell Significance Index: 58.2900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 4.1384
    Cell Significance Index: 66.4000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.9494
    Cell Significance Index: 80.2800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.5751
    Cell Significance Index: 923.6300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 2.1300
    Cell Significance Index: 130.9200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.7367
    Cell Significance Index: 213.5400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.4700
    Cell Significance Index: 76.5700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3531
    Cell Significance Index: 268.5200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.2912
    Cell Significance Index: 232.7700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.2267
    Cell Significance Index: 29.4200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.1698
    Cell Significance Index: 89.7700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1227
    Cell Significance Index: 111.0600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.0501
    Cell Significance Index: 9.6700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.0056
    Cell Significance Index: 16.9400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.9292
    Cell Significance Index: 64.2600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.9025
    Cell Significance Index: 12.9800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8806
    Cell Significance Index: 795.1200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7720
    Cell Significance Index: 341.3100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6650
    Cell Significance Index: 91.3200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.6478
    Cell Significance Index: 83.0500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5545
    Cell Significance Index: 90.1900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5387
    Cell Significance Index: 58.6000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3585
    Cell Significance Index: 71.9100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3532
    Cell Significance Index: 9.0800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3455
    Cell Significance Index: 20.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3028
    Cell Significance Index: 15.7300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2123
    Cell Significance Index: 115.9600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2073
    Cell Significance Index: 14.6600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1880
    Cell Significance Index: 3.6700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.1702
    Cell Significance Index: 2.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1436
    Cell Significance Index: 270.3100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1205
    Cell Significance Index: 83.3700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1158
    Cell Significance Index: 52.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0375
    Cell Significance Index: 1.0800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0228
    Cell Significance Index: 4.3300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0182
    Cell Significance Index: 13.8100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0062
    Cell Significance Index: 4.5800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0018
    Cell Significance Index: 0.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0056
    Cell Significance Index: -7.6300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0141
    Cell Significance Index: -8.9500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0182
    Cell Significance Index: -33.5300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0247
    Cell Significance Index: -37.9900
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0250
    Cell Significance Index: -0.2100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0258
    Cell Significance Index: -0.7200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0286
    Cell Significance Index: -21.2000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0413
    Cell Significance Index: -7.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0427
    Cell Significance Index: -26.6500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0457
    Cell Significance Index: -0.6500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0702
    Cell Significance Index: -39.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1275
    Cell Significance Index: -26.8700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1667
    Cell Significance Index: -10.2200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1876
    Cell Significance Index: -53.9700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2003
    Cell Significance Index: -22.9500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2086
    Cell Significance Index: -30.3200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2169
    Cell Significance Index: -9.8300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2305
    Cell Significance Index: -8.1000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2676
    Cell Significance Index: -27.3400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2820
    Cell Significance Index: -32.8600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2926
    Cell Significance Index: -33.4000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2972
    Cell Significance Index: -38.4000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3138
    Cell Significance Index: -32.6800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.3240
    Cell Significance Index: -5.7300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3247
    Cell Significance Index: -4.4300
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3762
    Cell Significance Index: -5.8200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.4387
    Cell Significance Index: -9.1000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4512
    Cell Significance Index: -53.2100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4634
    Cell Significance Index: -6.8400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4871
    Cell Significance Index: -38.5800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4964
    Cell Significance Index: -10.3900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4973
    Cell Significance Index: -12.4300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4998
    Cell Significance Index: -3.0200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5613
    Cell Significance Index: -11.9600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5614
    Cell Significance Index: -17.9800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.6069
    Cell Significance Index: -8.9600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.6183
    Cell Significance Index: -46.0800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.6249
    Cell Significance Index: -29.3700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.6386
    Cell Significance Index: -16.7900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6727
    Cell Significance Index: -45.2300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.7212
    Cell Significance Index: -12.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.7433
    Cell Significance Index: -41.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.8110
    Cell Significance Index: -52.3200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.9180
    Cell Significance Index: -57.8600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.9276
    Cell Significance Index: -26.5900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.9947
    Cell Significance Index: -19.9700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -1.0339
    Cell Significance Index: -15.5800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0414
    Cell Significance Index: -54.6800
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -1.1081
    Cell Significance Index: -18.2600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.1105
    Cell Significance Index: -38.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.1304
    Cell Significance Index: -50.0000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -1.1561
    Cell Significance Index: -30.8700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.1665
    Cell Significance Index: -42.8200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PLS3 shares high sequence homology with other plastins, particularly PLST1 and PLST2. The plastin family is characterized by the presence of a Dbl-homology domain, which is essential for their guanine nucleotide exchange activity and actin polymerization-promoting capabilities. PLS3 is also known to interact with actin filaments and form actin bundles, which are crucial for maintaining cellular structure and facilitating cell movement. Furthermore, PLS3 has been shown to bind to calcium ions, which may regulate its activity and interaction with other proteins. **Pathways and Functions** PLS3 is involved in several cellular pathways, including: 1. **Actin filament dynamics**: PLS3 regulates actin filament assembly, bundling, and network formation, which is essential for maintaining cellular structure and facilitating cell movement. 2. **Bone development**: PLS3 is highly expressed in bone-derived cells, suggesting its potential role in osteogenesis and bone remodeling. 3. **Calcium signaling**: PLS3 binds to calcium ions, which may regulate its activity and interaction with other proteins, including calmodulin. 4. **Cell migration and endocytosis**: PLS3 has been implicated in the regulation of cell migration and endocytosis, which are essential for various cellular processes, including development, differentiation, and tissue repair. **Clinical Significance** PLS3 has been identified as a potential biomarker for several diseases, including: 1. **Cardiac diseases**: Elevated PLS3 expression has been observed in cardiac muscle cells, suggesting its potential role in cardiac function and disease. 2. **Neurological disorders**: PLS3 has been implicated in the regulation of neural crest cell development, which is essential for the formation of the central nervous system. 3. **Kidney disease**: PLS3 is highly expressed in renal interstitial pericytes, suggesting its potential role in kidney function and disease. 4. **Cancer**: PLS3 has been shown to promote cell migration and invasion in various cancer types, suggesting its potential role as an oncogene. In conclusion, PLS3 is a multifunctional protein that plays a crucial role in regulating actin cytoskeleton dynamics, calcium signaling, and cell migration. Its expression in a wide range of cell types and its involvement in several cellular pathways suggest its potential as a biomarker for various diseases, including cardiac, neurological, and kidney disorders. Further studies are necessary to fully elucidate the functional significance of PLS3 and its potential therapeutic applications.

Genular Protein ID: 66705823

Symbol: PLST_HUMAN

Name: Plastin-3

UniProtKB Accession Codes:

P13797 A8K579 B1AQ09 B4DGB4 B7Z6M1 Q86YI6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 5 CTD 1 ChEBI 9 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 13 EMDB 5 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 6 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIR 1 PRIDE 1 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 6 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3211125

Title: Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts.

PubMed ID: 3211125

DOI: 10.1128/mcb.8.11.4659-4668.1988

PubMed ID: 2378651

Title: Correction of the N-terminal sequences of the human plastin isoforms by using anchored polymerase chain reaction: identification of a potential calcium-binding domain.

PubMed ID: 2378651

DOI: 10.1128/mcb.10.4.1818-1821.1990

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8428952

Title: Human plastin genes. Comparative gene structure, chromosome location, and differential expression in normal and neoplastic cells.

PubMed ID: 8428952

DOI: 10.1016/s0021-9258(18)53842-4

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24088043

Title: PLS3 mutations in X-linked osteoporosis with fractures.

PubMed ID: 24088043

DOI: 10.1056/nejmoa1308223

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 9302997

Title: The structure of an actin-crosslinking domain from human fimbrin.

PubMed ID: 9302997

DOI: 10.1038/nsb0997-708

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 24616189

Title: Osteoporosis caused by mutations in PLS3: clinical and bone tissue characteristics.

PubMed ID: 24616189

DOI: 10.1002/jbmr.2208

PubMed ID: 28748388

Title: PLS3 sequencing in childhood-onset primary osteoporosis identifies two novel disease-causing variants.

PubMed ID: 28748388

DOI: 10.1007/s00198-017-4150-9

PubMed ID: 33166085

Title: A novel mutation in PLS3 causes extremely rare X-linked osteogenesis imperfecta.

PubMed ID: 33166085

DOI: 10.1002/mgg3.1525

PubMed ID: 34946798

Title: X-Linked Osteogenesis Imperfecta Possibly Caused by a Novel Variant in PLS3.

PubMed ID: 34946798

DOI: 10.3390/genes12121851

PubMed ID: 37751738

Title: PLS3 missense variants affecting the actin-binding domains cause X-linked congenital diaphragmatic hernia and body-wall defects.

PubMed ID: 37751738

DOI: 10.1016/j.ajhg.2023.09.002

Sequence Information:

  • Length: 630
  • Mass: 70811
  • Checksum: 631E6F803DC56A56
  • Sequence:
    • MDEMATTQIS KDELDELKEA FAKVDLNSNG FICDYELHEL FKEANMPLPG YKVREIIQKL 
MLDGDRNKDG KISFDEFVYI FQEVKSSDIA KTFRKAINRK EGICALGGTS ELSSEGTQHS 
YSEEEKYAFV NWINKALEND PDCRHVIPMN PNTDDLFKAV GDGIVLCKMI NLSVPDTIDE 
RAINKKKLTP FIIQENLNLA LNSASAIGCH VVNIGAEDLR AGKPHLVLGL LWQIIKIGLF 
ADIELSRNEA LAALLRDGET LEELMKLSPE ELLLRWANFH LENSGWQKIN NFSADIKDSK 
AYFHLLNQIA PKGQKEGEPR IDINMSGFNE TDDLKRAESM LQQADKLGCR QFVTPADVVS 
GNPKLNLAFV ANLFNKYPAL TKPENQDIDW TLLEGETREE RTFRNWMNSL GVNPHVNHLY 
ADLQDALVIL QLYERIKVPV DWSKVNKPPY PKLGANMKKL ENCNYAVELG KHPAKFSLVG 
IGGQDLNDGN QTLTLALVWQ LMRRYTLNVL EDLGDGQKAN DDIIVNWVNR TLSEAGKSTS 
IQSFKDKTIS SSLAVVDLID AIQPGCINYD LVKSGNLTED DKHNNAKYAV SMARRIGARV 
YALPEDLVEV KPKMVMTVFA CLMGRGMKRV

Genular Protein ID: 1566042992

Symbol: B4DPW9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DPW9

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SMART 2 SMR 1 SUPFAM 2

Sequence Information:

  • Length: 603
  • Mass: 67599
  • Checksum: 54F52BD9A3F58C41
  • Sequence:
    • MDEMATTQIS KDELDELKEA FAKVDLNSNG FICDYELHEL FKEANMPLPG YKIFQEVKSS 
DIAKTFRKAI NRKEGICALG GTSELSSEGT QHSYSEEEKY AFVNWINKAL ENDPDCRHVI 
PMNPNTDDLF KAVGDGIVLC KMINLSVPDT IDERAINKKK LTPFIIQENL NLALNSASAI 
GCHVVNIGAE DLRAGKPHLV LGLLWQIIKI GLFADIELSR NEALAALLRD GETLEELMKL 
SPEELLLRWA NFHLENSGWQ KINNFSADIK DSKAYFHLLN QIAPKGQKEG EPRIDINMSG 
FNETDDLKRA ESMLQQADKL GCRQFVTPAD VVSGNPKLNL AFVANLFNKY PALTKPENQD 
IDWTLLEGET REERTFRNWM NSLGVNPHVN HLYADLQDAL VILQLYERIK VPVDWSKVNK 
PPYPKLGANM KKLENCNYAV ELGKHPAKFS LVGIGGQDLN DGNQTLTLAL VWQLMRRYTL 
NVLEDLGDGQ KANDDIIVNW VNRTLSEAGK STSIQSFKDK TISSSLAVVD LIDAIQPGCI 
NYDLVKSGNL TEDDKHNNAK YAVSMARRIG ARVYALPEDL VEVKPKMVMT VFACLMGRGM 
KRV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.