Details for: POLRMT
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 84.7985
Cell Significance Index: -13.1900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 52.4358
Cell Significance Index: -13.3000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 11.4846
Cell Significance Index: -14.1600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 4.6064
Cell Significance Index: -12.3400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.6568
Cell Significance Index: -14.4300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 3.3714
Cell Significance Index: -10.3600 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 2.8928
Cell Significance Index: 47.6700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.3348
Cell Significance Index: -5.1100 - Cell Name: germ cell (CL0000586)
Fold Change: 1.5184
Cell Significance Index: 11.4700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.9351
Cell Significance Index: 56.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.8559
Cell Significance Index: 162.8900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8469
Cell Significance Index: 137.7400 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.7997
Cell Significance Index: 12.8300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.6480
Cell Significance Index: 18.6700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5408
Cell Significance Index: 488.3400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5071
Cell Significance Index: 50.1600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4933
Cell Significance Index: 22.3600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4630
Cell Significance Index: 10.0300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4236
Cell Significance Index: 22.0100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3813
Cell Significance Index: 26.3700 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.3140
Cell Significance Index: 4.5000 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.2615
Cell Significance Index: 3.6700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.2454
Cell Significance Index: 6.6800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2331
Cell Significance Index: 6.2500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2027
Cell Significance Index: 36.5400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1855
Cell Significance Index: 11.9700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1806
Cell Significance Index: 24.8100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1780
Cell Significance Index: 35.7000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1742
Cell Significance Index: 34.5800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1682
Cell Significance Index: 10.6000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1652
Cell Significance Index: 90.2000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1539
Cell Significance Index: 4.3000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1385
Cell Significance Index: 61.2500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1381
Cell Significance Index: 16.9900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1319
Cell Significance Index: 6.2000 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.1258
Cell Significance Index: 1.8900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1227
Cell Significance Index: 5.7200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1096
Cell Significance Index: 75.8200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1083
Cell Significance Index: 38.8300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1028
Cell Significance Index: 2.1900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0773
Cell Significance Index: 5.4700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0637
Cell Significance Index: 2.2400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.0521
Cell Significance Index: 1.0800 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0413
Cell Significance Index: 5.2900 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0385
Cell Significance Index: 4.9700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0368
Cell Significance Index: 0.9200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0215
Cell Significance Index: 2.5400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0174
Cell Significance Index: 0.9200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0099
Cell Significance Index: 0.2600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0093
Cell Significance Index: 0.6900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0006
Cell Significance Index: 1.0700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0024
Cell Significance Index: -4.4800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0040
Cell Significance Index: -6.1400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0065
Cell Significance Index: -1.1100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0065
Cell Significance Index: -8.8700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0078
Cell Significance Index: -5.7500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0090
Cell Significance Index: -0.6900 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.0095
Cell Significance Index: -0.1500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0118
Cell Significance Index: -8.9400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0130
Cell Significance Index: -8.2600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0141
Cell Significance Index: -6.4000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0180
Cell Significance Index: -1.8400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0183
Cell Significance Index: -13.5400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0239
Cell Significance Index: -13.4800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0272
Cell Significance Index: -17.0100 - Cell Name: epidermal cell (CL0000362)
Fold Change: -0.0310
Cell Significance Index: -0.0700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0348
Cell Significance Index: -0.9300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0438
Cell Significance Index: -12.6000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0475
Cell Significance Index: -6.9100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0475
Cell Significance Index: -5.5400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0710
Cell Significance Index: -8.1300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0762
Cell Significance Index: -1.2800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0798
Cell Significance Index: -16.8100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0965
Cell Significance Index: -3.0900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0973
Cell Significance Index: -3.3800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1041
Cell Significance Index: -2.1800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1207
Cell Significance Index: -3.4600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1289
Cell Significance Index: -7.9000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1327
Cell Significance Index: -13.8200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1529
Cell Significance Index: -9.4000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1605
Cell Significance Index: -12.7100 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1605
Cell Significance Index: -4.1000 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1700
Cell Significance Index: -8.5900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1739
Cell Significance Index: -11.6900 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1789
Cell Significance Index: -5.2700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1894
Cell Significance Index: -10.6300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2012
Cell Significance Index: -2.7500 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2117
Cell Significance Index: -3.1900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.2156
Cell Significance Index: -2.5700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2303
Cell Significance Index: -5.9200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2331
Cell Significance Index: -10.3100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.2355
Cell Significance Index: -2.5600 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2542
Cell Significance Index: -3.6400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2597
Cell Significance Index: -4.4500 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.2703
Cell Significance Index: -11.0800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2704
Cell Significance Index: -10.2400 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.2705
Cell Significance Index: -2.8000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.2764
Cell Significance Index: -2.5500 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.2818
Cell Significance Index: -3.9500 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.2923
Cell Significance Index: -4.1000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3327240983
Symbol: RPOM_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9097968
Title: Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database.
PubMed ID: 9097968
DOI: 10.1093/hmg/6.4.615
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 12068295
Title: Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.
PubMed ID: 12068295
DOI: 10.1038/ng909
PubMed ID: 18685103
Title: Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro.
PubMed ID: 18685103
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21278163
Title: TEFM (c17orf42) is necessary for transcription of human mtDNA.
PubMed ID: 21278163
DOI: 10.1093/nar/gkq1224
PubMed ID: 23283301
Title: A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.
PubMed ID: 23283301
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 29445193
Title: Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy.
PubMed ID: 29445193
PubMed ID: 31226201
Title: Quantitative proteomics revealed C6orf203/MTRES1 as a factor preventing stress-induced transcription deficiency in human mitochondria.
PubMed ID: 31226201
DOI: 10.1093/nar/gkz542
PubMed ID: 29149603
Title: Structural Basis of Mitochondrial Transcription Initiation.
PubMed ID: 29149603
PubMed ID: 33602924
Title: POLRMT mutations impair mitochondrial transcription causing neurological disease.
PubMed ID: 33602924
Sequence Information:
- Length: 1230
- Mass: 138620
- Checksum: 47AFBF2E0884AEFA
- Sequence:
MSALCWGRGA AGLKRALRPC GRPGLPGKEG TAGGVCGPRR SSSASPQEQD QDRRKDWGHV ELLEVLQARV RQLQAESVSE VVVNRVDVAR LPECGSGDGS LQPPRKVQMG AKDATPVPCG RWAKILEKDK RTQQMRMQRL KAKLQMPFQS GEFKALTRRL QVEPRLLSKQ MAGCLEDCTR QAPESPWEEQ LARLLQEAPG KLSLDVEQAP SGQHSQAQLS GQQQRLLAFF KCCLLTDQLP LAHHLLVVHH GQRQKRKLLT LDMYNAVMLG WARQGAFKEL VYVLFMVKDA GLTPDLLSYA AALQCMGRQD QDAGTIERCL EQMSQEGLKL QALFTAVLLS EEDRATVLKA VHKVKPTFSL PPQLPPPVNT SKLLRDVYAK DGRVSYPKLH LPLKTLQCLF EKQLHMELAS RVCVVSVEKP TLPSKEVKHA RKTLKTLRDQ WEKALCRALR ETKNRLEREV YEGRFSLYPF LCLLDEREVV RMLLQVLQAL PAQGESFTTL ARELSARTFS RHVVQRQRVS GQVQALQNHY RKYLCLLASD AEVPEPCLPR QYWEELGAPE ALREQPWPLP VQMELGKLLA EMLVQATQMP CSLDKPHRSS RLVPVLYHVY SFRNVQQIGI LKPHPAYVQL LEKAAEPTLT FEAVDVPMLC PPLPWTSPHS GAFLLSPTKL MRTVEGATQH QELLETCPPT ALHGALDALT QLGNCAWRVN GRVLDLVLQL FQAKGCPQLG VPAPPSEAPQ PPEAHLPHSA APARKAELRR ELAHCQKVAR EMHSLRAEAL YRLSLAQHLR DRVFWLPHNM DFRGRTYPCP PHFNHLGSDV ARALLEFAQG RPLGPHGLDW LKIHLVNLTG LKKREPLRKR LAFAEEVMDD ILDSADQPLT GRKWWMGAEE PWQTLACCME VANAVRASDP AAYVSHLPVH QDGSCNGLQH YAALGRDSVG AASVNLEPSD VPQDVYSGVA AQVEVFRRQD AQRGMRVAQV LEGFITRKVV KQTVMTVVYG VTRYGGRLQI EKRLRELSDF PQEFVWEASH YLVRQVFKSL QEMFSGTRAI QHWLTESARL ISHMGSVVEW VTPLGVPVIQ PYRLDSKVKQ IGGGIQSITY THNGDISRKP NTRKQKNGFP PNFIHSLDSS HMMLTALHCY RKGLTFVSVH DCYWTHAADV SVMNQVCREQ FVRLHSEPIL QDLSRFLVKR FCSEPQKILE ASQLKETLQA VPKPGAFDLE QVKRSTYFFS
Genular Protein ID: 255403461
Symbol: Q4G0F4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 1230
- Mass: 138515
- Checksum: 3FB3E068968115F6
- Sequence:
MSALCWGRGA AGLKRALRPC GRPGLPGKEG TAGGVCGPRR SSSASPQEQD QDRRKDWGHV ELLEVLQARV RQLQAESVSE VVVNRVDVAR LPECGSGDGS LQPPRKVQMG AKDATPVPCG RWAKILEKDK RTQQMRMQRL KAKLQMPFQS GEFKALTRRL QVEPRLLSKQ MAGCLEDCTR QAPESPWEEQ LAQLLQEAPG KLSLDVEQAP SGQHSQAQLS GQQQRLLAFF KCCLLTDQLP LAHHLLVVHH GQRQKRKLLT LDMYNAVMLG WARQGAFKEL VYVLFMVKDA GLTPDLLSYA AALQCMGRQD QDAGTIERCL EQMSQEGLKL QALFTAVLLS EEDRATVLKA VHKVKPTFSL PPQLPPPVNT SKLLRDVYAK DGRVSYPKLH LPLKTLQCLF EKQLHMELAS RVCVVSVEKP TLPSKEVKHA RKTLKTLRDQ WEKALCRALR ETKNRLEREV YEGRFSLYPF LCLLDEREVV RMLLQVLQAL PAQGESFTTL ARELSARTFS RHVVQRQRVS GQVQALQNHY RKYLCLLASD AEVPEPCLPR QYWEALGAPE ALREQPWPLP VQMELGKLLA EMLVQATQMP CSLDKPHHSS RLVPVLYHVY SFRNVQQIGI LKPHPAYVQL LEKAAEPTLT FEAVDVPMLC PPLPWTSPHS GAFLLSPTKL MRTVEGATQH QELLETCPPT ALHGALDALT QLGNCAWRVN GRVLDLVLQL FQAKGCPQLG VPAPPSEAPQ PPEAHLPHSA APARKAELRR ELAHCQKVAR EMHSLRAEAL YRLSLAQHLR DRVFWLPHNM DFRGRTYPCP PHFNHLGSDV ARALLEFAQG RPLGPHGLDW LKIHLVNLTG LKKREPLRKR LAFAEEVMDD ILDSADQPLT GRKWWMGAEE PWQTLACCME VANAVRASDP AAYVSHLPVH QDGSCNGLQH YAALGRDSVG AASVNLEPSD VPQDVYSGVA AQVEVFRRQD AQRGMRVAQV LEGFITRKVV KQTVMTVVYG VTRYGGRLQI EKRLRELSDF PQEFVWEASH YLVRQVFKSL QEMFSGTRAI QHWLTESARL ISHMGSVVEW VTPLGVPVIQ PYRLDSKVKQ IGGGIQSITY THNGDISRKP NTRKQKNGFP PNFIHSLDSS HMMLTALHCY RKGLTFVSVH DCYWTHAADV SVMNQVCREQ FVRLHSEPIL QDLSRFLVKR FCSEPQKILE ASQLKETLQA VPKPGAFDLE QVKRSTYFFS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.