Details for: PPL

Gene ID: 5493

Symbol: PPL

Ensembl ID: ENSG00000118898

Description: periplakin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 145.8097
    Cell Significance Index: -22.6800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 90.0083
    Cell Significance Index: -22.8300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 18.5914
    Cell Significance Index: -17.7500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.5246
    Cell Significance Index: -22.8400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.7388
    Cell Significance Index: -23.4100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.8261
    Cell Significance Index: -22.9900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.4218
    Cell Significance Index: 67.6800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.1767
    Cell Significance Index: 20.0500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.1373
    Cell Significance Index: 16.1900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1188
    Cell Significance Index: 58.1200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.9463
    Cell Significance Index: 47.8200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.8920
    Cell Significance Index: 17.4100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6736
    Cell Significance Index: 82.8300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6501
    Cell Significance Index: 64.3100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6354
    Cell Significance Index: 573.7300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5971
    Cell Significance Index: 118.4900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5883
    Cell Significance Index: 16.9500
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.5708
    Cell Significance Index: 6.6400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5218
    Cell Significance Index: 104.6800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5088
    Cell Significance Index: 91.7200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5070
    Cell Significance Index: 276.8900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4908
    Cell Significance Index: 53.3900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4876
    Cell Significance Index: 215.5600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.4782
    Cell Significance Index: 13.0200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4145
    Cell Significance Index: 8.9800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3885
    Cell Significance Index: 63.1900
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.3882
    Cell Significance Index: 2.6300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.3266
    Cell Significance Index: 15.3500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3126
    Cell Significance Index: 40.3900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2732
    Cell Significance Index: 18.8900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2549
    Cell Significance Index: 48.5000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2423
    Cell Significance Index: 18.6000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1315
    Cell Significance Index: 5.9600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0950
    Cell Significance Index: 129.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0939
    Cell Significance Index: 173.2400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0917
    Cell Significance Index: 63.4200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0859
    Cell Significance Index: 3.0200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0789
    Cell Significance Index: 5.8800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0638
    Cell Significance Index: 98.2300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0576
    Cell Significance Index: 36.6000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0558
    Cell Significance Index: 3.7600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0540
    Cell Significance Index: 2.5200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0130
    Cell Significance Index: 24.5000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0001
    Cell Significance Index: 0.1000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0092
    Cell Significance Index: -3.3000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0097
    Cell Significance Index: -6.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0098
    Cell Significance Index: -7.4300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0190
    Cell Significance Index: -13.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0244
    Cell Significance Index: -13.7600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0283
    Cell Significance Index: -5.9600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0385
    Cell Significance Index: -6.5800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0396
    Cell Significance Index: -0.5400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0431
    Cell Significance Index: -19.5400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0458
    Cell Significance Index: -6.6600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0463
    Cell Significance Index: -3.2800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0553
    Cell Significance Index: -6.4500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0559
    Cell Significance Index: -16.0800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0560
    Cell Significance Index: -6.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0717
    Cell Significance Index: -8.2100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0772
    Cell Significance Index: -1.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0943
    Cell Significance Index: -12.9500
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.0973
    Cell Significance Index: -0.6000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0979
    Cell Significance Index: -2.0300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1097
    Cell Significance Index: -14.0600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1164
    Cell Significance Index: -1.9600
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.1250
    Cell Significance Index: -1.1100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1283
    Cell Significance Index: -13.1100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1525
    Cell Significance Index: -2.4200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1990
    Cell Significance Index: -23.4700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2111
    Cell Significance Index: -12.9400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2137
    Cell Significance Index: -11.2200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2141
    Cell Significance Index: -22.2900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2300
    Cell Significance Index: -7.3700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2559
    Cell Significance Index: -20.2700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2756
    Cell Significance Index: -17.3700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2821
    Cell Significance Index: -4.8400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3298
    Cell Significance Index: -20.2700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3314
    Cell Significance Index: -17.2600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3347
    Cell Significance Index: -18.7800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3366
    Cell Significance Index: -21.7200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.3449
    Cell Significance Index: -5.0900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3510
    Cell Significance Index: -11.1000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3634
    Cell Significance Index: -13.3400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3803
    Cell Significance Index: -16.8200
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.4139
    Cell Significance Index: -4.2700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4223
    Cell Significance Index: -12.4400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4312
    Cell Significance Index: -6.1800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4322
    Cell Significance Index: -12.3900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4489
    Cell Significance Index: -11.5400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4561
    Cell Significance Index: -17.2700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4571
    Cell Significance Index: -10.5600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4740
    Cell Significance Index: -5.6500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4820
    Cell Significance Index: -4.9900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5004
    Cell Significance Index: -17.5300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5071
    Cell Significance Index: -16.1500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5168
    Cell Significance Index: -17.9600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5544
    Cell Significance Index: -12.1400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5728
    Cell Significance Index: -18.7600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.5908
    Cell Significance Index: -14.7600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.6032
    Cell Significance Index: -8.9100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** Periplakin is a member of the plakin family of proteins, which are known for their ability to bind to intermediate filaments, actin filaments, and other proteins. This protein is characterized by its ability to cross-link intermediate filaments, thereby providing mechanical stability to cells. PPL is also involved in the formation of desmosomes, which are intercellular junctions that maintain tissue integrity. Furthermore, PPL has been shown to interact with various proteins, including butyrophilin and cadherins, which are essential for maintaining cell-cell adhesion and signaling. **Pathways and Functions:** PPL is involved in several critical cellular processes, including: 1. **Cytoskeleton organization:** PPL plays a crucial role in maintaining the structural integrity of the cytoskeleton by cross-linking intermediate filaments. 2. **Cell-cell adhesion:** PPL interacts with cadherins and other proteins to maintain cell-cell adhesion, which is essential for tissue integrity. 3. **Immune response:** PPL has been shown to interact with butyrophilin, which is involved in the adaptive immune response. 4. **Keratinization:** PPL is involved in the process of keratinization, which is essential for the development of stratified epithelial cells. 5. **Wound healing:** PPL has been shown to play a role in wound healing by promoting the formation of desmosomes. **Clinical Significance:** Dysregulation of PPL has been implicated in various diseases, including: 1. **Skin disorders:** Mutations in the PPL gene have been associated with skin disorders such as epidermolysis bullosa simplex (EBS) and epidermolysis bullosa acquisita (EBA). 2. **Cancer:** PPL has been shown to play a role in cancer progression by promoting cell migration and invasion. 3. **Autoimmune diseases:** PPL has been implicated in autoimmune diseases such as pemphigus and pemphigoid. In conclusion, periplakin is a multifunctional protein that plays a critical role in maintaining epithelial cell integrity, immune response, and wound healing. Further research is needed to fully elucidate the functions and significance of PPL in various diseases. **References:** * [Insert references here] Note: The references section should include a list of relevant studies and publications on the topic of periplakin.

Genular Protein ID: 4024215268

Symbol: PEPL_HUMAN

Name: Periplakin

UniProtKB Accession Codes:

O60437 O60314 O60454 Q14C98

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRIDE 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9412476

Title: Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin.

PubMed ID: 9412476

DOI: 10.1083/jcb.139.7.1835

PubMed ID: 9521878

Title: cDNA cloning, mRNA expression, and chromosomal mapping of human and mouse periplakin genes.

PubMed ID: 9521878

DOI: 10.1006/geno.1997.5188

PubMed ID: 10051401

Title: Human periplakin: genomic organization in a clonally unstable region of chromosome 16p with an abundance of repetitive sequence elements.

PubMed ID: 10051401

DOI: 10.1006/geno.1998.5704

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9628581

Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9628581

DOI: 10.1093/dnares/5.1.31

PubMed ID: 12244133

Title: Binding of protein kinase B to the plakin family member periplakin.

PubMed ID: 12244133

DOI: 10.1242/jcs.00069

PubMed ID: 12853457

Title: Characterization of periphilin, a widespread, highly insoluble nuclear protein and potential constituent of the keratinocyte cornified envelope.

PubMed ID: 12853457

DOI: 10.1074/jbc.m303896200

PubMed ID: 15229321

Title: Direct interaction between FcgammaRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacity.

PubMed ID: 15229321

DOI: 10.1073/pnas.0401217101

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1756
  • Mass: 204747
  • Checksum: EA7EAF3E756D78B4
  • Sequence:
    • MNSLFRKRNK GKYSPTVQTR SISNKELSEL IEQLQKNADQ VEKNIVDTEA KMQSDLARLQ 
EGRQPEHRDV TLQKVLDSEK LLYVLEADAA IAKHMKHPQG DMIAEDIRQL KERVTNLRGK 
HKQIYRLAVK EVDPQVNWAA LVEEKLDKLN NQSFGTDLPL VDHQVEEHNI FHNEVKAIGP 
HLAKDGDKEQ NSELRAKYQK LLAASQARQQ HLSSLQDYMQ RCTNELYWLD QQAKGRMQYD 
WSDRNLDYPS RRRQYENFIN RNLEAKEERI NKLHSEGDQL LAAEHPGRNS IEAHMEAVHA 
DWKEYLNLLI CEESHLKYME DYHQFHEDVK DAQELLRKVD SDLNQKYGPD FKDRYQIELL 
LRELDDQEKV LDKYEDVVQG LQKRGQQVVP LKYRRETPLK PIPVEALCDF EGEQGLISRG 
YSYTLQKNNG ESWELMDSAG NKLIAPAVCF VIPPTDPEAL ALADSLGSQY RSVRQKAAGS 
KRTLQQRYEV LKTENPGDAS DLQGRQLLAG LDKVASDLDR QEKAITGILR PPLEQGRAVQ 
DSAERAKDLK NITNELLRIE PEKTRSTAEG EAFIQALPGS GTTPLLRTRV EDTNRKYEHL 
LQLLDLAQEK VDVANRLEKS LQQSWELLAT HENHLNQDDT VPESSRVLDS KGQELAAMAC 
ELQAQKSLLG EVEQNLQAAK QCSSTLASRF QEHCPDLERQ EAEVHKLGQR FNNLRQQVER 
RAQSLQSAKA AYEHFHRGHD HVLQFLVSIP SYEPQETDSL SQMETKLKNQ KNLLDEIASR 
EQEVQKICAN SQQYQQAVKD YELEAEKLRS LLDLENGRRS HVSKRARLQS PATKVKEEEA 
ALAAKFTEVY AINRQRLQNL EFALNLLRQQ PEVEVTHETL QRNRPDSGVE EAWKIRKELD 
EETERRRQLE NEVKSTQEEI WTLRNQGPQE SVVRKEVLKK VPDPVLEESF QQLQRTLAEE 
QHKNQLLQEE LEALQLQLRA LEQETRDGGQ EYVVKEVLRI EPDRAQADEV LQLREELEAL 
RRQKGAREAE VLLLQQRVAA LAEEKSRAQE KVTEKEVVKL QNDPQLEAEY QQLQEDHQRQ 
DQLREKQEEE LSFLQDKLKR LEKERAMAEG KITVKEVLKV EKDAATEREV SDLTRQYEDE 
AAKARASQRE KTELLRKIWA LEEENAKVVV QEKVREIVRP DPKAESEVAN LRLELVEQER 
KYRGAEEQLR SYQSELEALR RRGPQVEVKE VTKEVIKYKT DPEMEKELQR LREEIVDKTR 
LIERCDLEIY QLKKEIQALK DTKPQVQTKE VVQEILQFQE DPQTKEEVAS LRAKLSEEQK 
KQVDLERERA SQEEQIARKE EELSRVKERV VQQEVVRYEE EPGLRAEASA FAESIDVELR 
QIDKLRAELR RLQRRRTELE RQLEELERER QARREAEREV QRLQQRLAAL EQEEAEAREK 
VTHTQKVVLQ QDPQQAREHA LLRLQLEEEQ HRRQLLEGEL ETLRRKLAAL EKAEVKEKVV 
LSESVQVEKG DTEQEIQRLK SSLEEESRSK RELDVEVSRL EARLSELEFH NSKSSKELDF 
LREENHKLQL ERQNLQLETR RLQSEINMAA TETRDLRNMT VADSGTNHDS RLWSLERELD 
DLKRLSKDKD LEIDELQKRL GSVAVKREQR ENHLRRSIVV IHPDTGRELS PEEAHRAGLI 
DWNMFVKLRS QECDWEEISV KGPNGESSVI HDRKSGKKFS IEEALQSGRL TPAQYDRYVN 
KDMSIQELAV LVSGQK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.