Details for: PPP1R10
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 357.9345
Cell Significance Index: -55.6800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 207.9692
Cell Significance Index: -52.7500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 142.4842
Cell Significance Index: -67.2700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 129.6223
Cell Significance Index: -52.6600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 119.9879
Cell Significance Index: -61.7200 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 100.3842
Cell Significance Index: -67.3600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 55.6275
Cell Significance Index: -53.1100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 46.4777
Cell Significance Index: -57.3100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 22.7522
Cell Significance Index: -60.9500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.8275
Cell Significance Index: -58.5100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.8734
Cell Significance Index: -39.5400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 2.9512
Cell Significance Index: 133.7700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.8262
Cell Significance Index: 38.5600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.1226
Cell Significance Index: 136.9400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.9318
Cell Significance Index: 55.6600 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.4969
Cell Significance Index: 191.9000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.3203
Cell Significance Index: 181.3100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.3057
Cell Significance Index: 160.5500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.2469
Cell Significance Index: 250.1200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.2258
Cell Significance Index: 220.9700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9973
Cell Significance Index: 900.4600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.9712
Cell Significance Index: 429.3900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.9434
Cell Significance Index: 44.3400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9080
Cell Significance Index: 180.1900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.9034
Cell Significance Index: 24.5900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8986
Cell Significance Index: 146.1600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.8894
Cell Significance Index: 46.2000 - Cell Name: peg cell (CL4033014)
Fold Change: 0.8886
Cell Significance Index: 20.5300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.8573
Cell Significance Index: 468.1700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.7762
Cell Significance Index: 36.1900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6381
Cell Significance Index: 63.1200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.6335
Cell Significance Index: 35.5500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.6031
Cell Significance Index: 216.3200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.5478
Cell Significance Index: 38.7400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.4765
Cell Significance Index: 13.6600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4538
Cell Significance Index: 313.8700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.3775
Cell Significance Index: 28.9700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.3395
Cell Significance Index: 17.1600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.3254
Cell Significance Index: 16.9500 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1528
Cell Significance Index: 19.7500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0971
Cell Significance Index: 6.1200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0952
Cell Significance Index: 179.3000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0819
Cell Significance Index: 15.5900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0731
Cell Significance Index: 12.4900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0567
Cell Significance Index: 87.2200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0371
Cell Significance Index: 50.3800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0218
Cell Significance Index: 40.1900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0136
Cell Significance Index: 8.6200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0083
Cell Significance Index: 6.0800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0071
Cell Significance Index: -0.1900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0104
Cell Significance Index: -0.7200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0230
Cell Significance Index: -17.0200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0274
Cell Significance Index: -12.4500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0497
Cell Significance Index: -37.6200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0537
Cell Significance Index: -33.5100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0681
Cell Significance Index: -8.0300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0708
Cell Significance Index: -39.9100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0998
Cell Significance Index: -1.1900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1009
Cell Significance Index: -10.3100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1424
Cell Significance Index: -3.9800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1541
Cell Significance Index: -22.4000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1610
Cell Significance Index: -33.9100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1849
Cell Significance Index: -13.7800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2121
Cell Significance Index: -61.0400 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.2433
Cell Significance Index: -5.2000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2509
Cell Significance Index: -28.7500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2524
Cell Significance Index: -29.4100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2616
Cell Significance Index: -29.8600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2658
Cell Significance Index: -6.9900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2808
Cell Significance Index: -14.7500 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.3944
Cell Significance Index: -3.0400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.4275
Cell Significance Index: -7.1600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4558
Cell Significance Index: -20.1600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4694
Cell Significance Index: -48.8800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4912
Cell Significance Index: -17.0700 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: -0.5002
Cell Significance Index: -3.9800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.5188
Cell Significance Index: -10.8600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5616
Cell Significance Index: -9.6300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6095
Cell Significance Index: -23.0800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6181
Cell Significance Index: -48.9500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.6396
Cell Significance Index: -16.4400 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.6453
Cell Significance Index: -5.4200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.6915
Cell Significance Index: -24.3000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.7125
Cell Significance Index: -22.8200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.7201
Cell Significance Index: -15.6000 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.7332
Cell Significance Index: -7.5900 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.8271
Cell Significance Index: -26.1600 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.8819
Cell Significance Index: -13.0200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.8937
Cell Significance Index: -22.8300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.9118
Cell Significance Index: -55.9000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.9742
Cell Significance Index: -26.0600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.9847
Cell Significance Index: -28.9200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.9912
Cell Significance Index: -11.2600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -1.0360
Cell Significance Index: -20.2200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -1.0658
Cell Significance Index: -9.8200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.0660
Cell Significance Index: -34.9000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.0727
Cell Significance Index: -34.1700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.1050
Cell Significance Index: -38.7100 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -1.1338
Cell Significance Index: -16.1400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.1471
Cell Significance Index: -28.6800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1703463680
Symbol: PP1RA_HUMAN
Name: Serine/threonine-protein phosphatase 1 regulatory subunit 10
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9784381
Title: Cloning of a new gene (FB19) within HLA class I region.
PubMed ID: 9784381
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 9450550
Title: Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity.
PubMed ID: 9450550
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 940
- Mass: 99058
- Checksum: 49EE42961D734121
- Sequence:
MGSGPIDPKE LLKGLDSFLN RDGEVKSVDG ISKIFSLMKE ARKMVSRCTY LNILLQTRSP EILVKFIDVG GYKLLNNWLT YSKTTNNIPL LQQILLTLQH LPLTVDHLKQ NNTAKLVKQL SKSSEDEELR KLASVLVSDW MAVIRSQSST QPAEKDKKKR KDEGKSRTTL PERPLTEVKA ETRAEEAPEK KREKPKSLRT TAPSHAKFRS TGLELETPSL VPVKKNASTV VVSDKYNLKP IPLKRQSNVA APGDATPPAE KKYKPLNTTP NATKEIKVKI IPPQPMEGLG FLDALNSAPV PGIKIKKKKK VLSPTAAKPS PFEGKTSTEP STAKPSSPEP APPSEAMDAD RPGTPVPPVE VPELMDTASL EPGALDAKPV ESPGDPNQLT RKGRKRKSVT WPEEGKLREY FYFELDETER VNVNKIKDFG EAAKREILSD RHAFETARRL SHDNMEEKVP WVCPRPLVLP SPLVTPGSNS QERYIQAERE KGILQELFLN KESPHEPDPE PYEPIPPKLI PLDEECSMDE TPYVETLEPG GSGGSPDGAG GSKLPPVLAN LMGSMGAGKG PQGPGGGGIN VQEILTSIMG SPNSHPSEEL LKQPDYSDKI KQMLVPHGLL GPGPIANGFP PGGPGGPKGM QHFPPGPGGP MPGPHGGPGG PVGPRLLGPP PPPRGGDPFW DGPGDPMRGG PMRGGPGPGP GPYHRGRGGR GGNEPPPPPP PFRGARGGRS GGGPPNGRGG PGGGMVGGGG HRPHEGPGGG MGNSSGHRPH EGPGGGMGSG HRPHEGPGGS MGGGGGHRPH EGPGGGISGG SGHRPHEGPG GGMGAGGGHR PHEGPGGSMG GSGGHRPHEG PGHGGPHGHR PHDVPGHRGH DHRGPPPHEH RGHDGPGHGG GGHRGHDGGH SHGGDMSNRP VCRHFMMKGN CRYENNCAFY HPGVNGPPLP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.