Details for: PREP

Gene ID: 5550

Symbol: PREP

Ensembl ID: ENSG00000085377

Description: prolyl endopeptidase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 159.0534
    Cell Significance Index: -24.7400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 97.1640
    Cell Significance Index: -24.6500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 61.9982
    Cell Significance Index: -25.5400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 57.4851
    Cell Significance Index: -27.1400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 56.5898
    Cell Significance Index: -22.9900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 40.4979
    Cell Significance Index: -27.1800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 20.7874
    Cell Significance Index: -25.6300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.0449
    Cell Significance Index: -24.2300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.4427
    Cell Significance Index: -22.8600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.5686
    Cell Significance Index: -25.9200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.0221
    Cell Significance Index: -13.1800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.0364
    Cell Significance Index: 209.9900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.7726
    Cell Significance Index: 47.3300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7223
    Cell Significance Index: 345.4900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.6821
    Cell Significance Index: 1518.8500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.2224
    Cell Significance Index: 198.8200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.1578
    Cell Significance Index: 52.4800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.0469
    Cell Significance Index: 26.1700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0405
    Cell Significance Index: 206.5000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.8856
    Cell Significance Index: 13.2700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7190
    Cell Significance Index: 9.8100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6697
    Cell Significance Index: 19.3000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.6449
    Cell Significance Index: 43.3600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.6407
    Cell Significance Index: 14.0300
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.5968
    Cell Significance Index: 6.0200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5801
    Cell Significance Index: 44.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5463
    Cell Significance Index: 28.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5452
    Cell Significance Index: 195.5600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5207
    Cell Significance Index: 11.2800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4886
    Cell Significance Index: 21.6100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4528
    Cell Significance Index: 17.1500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4396
    Cell Significance Index: 24.6700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4060
    Cell Significance Index: 10.4400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3868
    Cell Significance Index: 23.7800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3678
    Cell Significance Index: 66.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3325
    Cell Significance Index: 229.9600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2887
    Cell Significance Index: 35.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2351
    Cell Significance Index: 6.5700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.2289
    Cell Significance Index: 5.4900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2009
    Cell Significance Index: 38.2400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1700
    Cell Significance Index: 3.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1473
    Cell Significance Index: 80.4400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1400
    Cell Significance Index: 19.2200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1190
    Cell Significance Index: 3.8100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1094
    Cell Significance Index: 2.2700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1009
    Cell Significance Index: 1.9700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0988
    Cell Significance Index: 43.6900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.0590
    Cell Significance Index: 1.4400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0579
    Cell Significance Index: 5.7300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0329
    Cell Significance Index: 44.6800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0258
    Cell Significance Index: 4.4000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0197
    Cell Significance Index: 0.9200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0191
    Cell Significance Index: 35.9400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0091
    Cell Significance Index: 4.1500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0066
    Cell Significance Index: 0.3100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0051
    Cell Significance Index: 7.8700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0041
    Cell Significance Index: 2.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0002
    Cell Significance Index: -0.4100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0035
    Cell Significance Index: -0.1000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0205
    Cell Significance Index: -0.4300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0209
    Cell Significance Index: -1.3200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0212
    Cell Significance Index: -16.0300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0283
    Cell Significance Index: -20.7700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0294
    Cell Significance Index: -21.8000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0312
    Cell Significance Index: -4.0000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0378
    Cell Significance Index: -5.4900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0404
    Cell Significance Index: -4.7700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0434
    Cell Significance Index: -24.4700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0458
    Cell Significance Index: -28.5800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0753
    Cell Significance Index: -9.7300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0782
    Cell Significance Index: -1.3400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0786
    Cell Significance Index: -22.6100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0817
    Cell Significance Index: -9.5200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1032
    Cell Significance Index: -10.5400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1257
    Cell Significance Index: -9.3700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1306
    Cell Significance Index: -27.5100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1416
    Cell Significance Index: -9.1400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1501
    Cell Significance Index: -5.2800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1537
    Cell Significance Index: -5.3400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1586
    Cell Significance Index: -4.2500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1593
    Cell Significance Index: -8.3000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1655
    Cell Significance Index: -11.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1738
    Cell Significance Index: -19.9100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1790
    Cell Significance Index: -9.4000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1868
    Cell Significance Index: -2.6800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1910
    Cell Significance Index: -2.8200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1913
    Cell Significance Index: -4.0600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2240
    Cell Significance Index: -5.8900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2267
    Cell Significance Index: -3.2600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2298
    Cell Significance Index: -23.9300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2413
    Cell Significance Index: -4.0700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2965
    Cell Significance Index: -2.7300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3024
    Cell Significance Index: -5.9800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3073
    Cell Significance Index: -18.8400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3093
    Cell Significance Index: -24.5000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3215
    Cell Significance Index: -10.2400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3239
    Cell Significance Index: -5.4200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3439
    Cell Significance Index: -11.2600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3801
    Cell Significance Index: -4.7400
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.4053
    Cell Significance Index: -5.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PREP is a serine-type endopeptidase enzyme with a molecular weight of approximately 60 kDa. It is primarily expressed in the CNS, particularly in neurons and glial cells. PREP is activated by calcium ions and is inhibited by L-phenylalanine, L-tryptophan, and L-tyrosine. The enzyme is also known to interact with various proteins, including neurotransmitter receptors and growth factor receptors, to modulate their activity. **Pathways and Functions:** PREP is involved in several signaling pathways that regulate neurotransmission, synaptic plasticity, and neuronal survival. These pathways include: 1. **Protein degradation:** PREP cleaves and degrades peptides and proteins, including neurotransmitters, hormones, and growth factors, such as acetylcholine, dopamine, and nerve growth factor (NGF). 2. **Neurotransmitter regulation:** PREP modulates the activity of neurotransmitters, such as GABA, glutamate, and acetylcholine, by cleaving them into inactive fragments. 3. **Synaptic plasticity:** PREP regulates synaptic plasticity by modulating the activity of neurotransmitter receptors and growth factor receptors, leading to changes in neuronal excitability and synaptic strength. 4. **Neuronal survival:** PREP plays a role in neuronal survival by regulating the activity of growth factors, such as NGF, and by modulating the expression of genes involved in neuronal survival and death. **Clinical Significance:** Dysregulation of PREP has been implicated in various neurological disorders, including: 1. **Alzheimer's disease:** Overexpression of PREP has been linked to the accumulation of amyloid-beta peptides, a hallmark of Alzheimer's disease. 2. **Parkinson's disease:** Alterations in PREP activity have been observed in the brains of patients with Parkinson's disease, leading to changes in dopamine levels and motor function. 3. **Neurodegenerative disorders:** PREP has been implicated in the pathogenesis of other neurodegenerative disorders, including Huntington's disease, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). 4. **Neurodevelopmental disorders:** PREP has been linked to neurodevelopmental disorders, such as autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). In conclusion, PREP is a critical enzyme that regulates various physiological processes in the CNS, including neurotransmission, synaptic plasticity, and neuronal survival. Dysregulation of PREP has been implicated in various neurological disorders, highlighting the importance of this enzyme in understanding the pathogenesis of these diseases. Further research is needed to elucidate the mechanisms by which PREP regulates CNS function and to develop therapeutic strategies to modulate its activity in the treatment of neurological disorders.

Genular Protein ID: 55001366

Symbol: PPCE_HUMAN

Name: Prolyl endopeptidase

UniProtKB Accession Codes:

P48147 Q8N6D4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 8 DrugCentral 1 EC 2 EMBL 8 ESTHER 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRIDE 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7959018

Title: Cloning and sequence analysis of the gene encoding human lymphocyte prolyl endopeptidase.

PubMed ID: 7959018

DOI: 10.1016/0378-1119(94)90177-5

PubMed ID: 8089089

Title: Molecular cloning and characterization of prolyl endopeptidase from human T cells.

PubMed ID: 8089089

DOI: 10.1093/oxfordjournals.jbchem.a124402

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7588785

Title: The purification, characterization and analysis of primary and secondary-structure of prolyl oligopeptidase from human lymphocytes. Evidence that the enzyme belongs to the alpha/beta hydrolase fold family.

PubMed ID: 7588785

DOI: 10.1111/j.1432-1033.1995.432_2.x

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 18606544

Title: Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP).

PubMed ID: 18606544

DOI: 10.1016/j.bmcl.2008.06.067

Sequence Information:

  • Length: 710
  • Mass: 80700
  • Checksum: 139072B990820B90
  • Sequence:
    • MLSLQYPDVY RDETAVQDYH GHKICDPYAW LEDPDSEQTK AFVEAQNKIT VPFLEQCPIR 
GLYKERMTEL YDYPKYSCHF KKGKRYFYFY NTGLQNQRVL YVQDSLEGEA RVFLDPNILS 
DDGTVALRGY AFSEDGEYFA YGLSASGSDW VTIKFMKVDG AKELPDVLER VKFSCMAWTH 
DGKGMFYNSY PQQDGKSDGT ETSTNLHQKL YYHVLGTDQS EDILCAEFPD EPKWMGGAEL 
SDDGRYVLLS IREGCDPVNR LWYCDLQQES SGIAGILKWV KLIDNFEGEY DYVTNEGTVF 
TFKTNRQSPN YRVINIDFRD PEESKWKVLV PEHEKDVLEW IACVRSNFLV LCYLHDVKNI 
LQLHDLTTGA LLKTFPLDVG SIVGYSGQKK DTEIFYQFTS FLSPGIIYHC DLTKEELEPR 
VFREVTVKGI DASDYQTVQI FYPSKDGTKI PMFIVHKKGI KLDGSHPAFL YGYGGFNISI 
TPNYSVSRLI FVRHMGGILA VANIRGGGEY GETWHKGGIL ANKQNCFDDF QCAAEYLIKE 
GYTSPKRLTI NGGSNGGLLV AACANQRPDL FGCVIAQVGV MDMLKFHKYT IGHAWTTDYG 
CSDSKQHFEW LVKYSPLHNV KLPEADDIQY PSMLLLTADH DDRVVPLHSL KFIATLQYIV 
GRSRKQSNPL LIHVDTKAGH GAGKPTAKVI EEVSDMFAFI ARCLNVDWIP

Genular Protein ID: 1079657108

Symbol: B2RAH7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RAH7

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 ESTHER 1 GO 2 Gene3D 2 IntAct 1 InterPro 6 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 4 RefSeq 1 RuleBase 1 SUPFAM 2

Sequence Information:

  • Length: 710
  • Mass: 80734
  • Checksum: 948A989C774C6B37
  • Sequence:
    • MLSFQYPDVY RDETAVQDYH GHKICDPYAW LEDPDSEQTK AFVEAQNKIT VPFLEQCPIR 
GLYKERMTEL YDYPKYSCHF KKGKRYFYFY NTGLQNQRVL YVQDSLEGEA RVFLDPNILS 
DDGTVALRGY AFSEDGEYFA YGLSASGSDW VTIKFMKVDG AKELPDVLER VKFSCMAWTH 
DGKGMFYNSY PQQDGKSDGT ETSTNLHQKL YYHVLGTDQS EDILCAEFPD EPKWMGGAEL 
SDDGRYVLLS IREGCDPVNR LWYCDLQQES SGIAGILKWV KLIDNFEGEY DYVTNEGTVF 
TFKTNRQSPN YRVINIDFRD PEESKWKVLV PEHEKDVLEW IACVRSNFLV LCYLHDVKNI 
LQLHDLTTGA LLKTFPLDVG SIVGYSGQKK DTEIFYQFTS FLSPGIIYHC DLTKEELEPR 
VFREVTVKGI DASDYQTVQI FYPSKDGTKI PMFIVHKKGI KLDGSHPAFL YGYGGFNISI 
TPNYSVSRLI FVRHMGGILA VANIRGGGEY GETWHKGGIL ANKQNCFDDF QCAAEYLIKE 
GYTSPKRLTI NGGSNGGLLV AACANQRPDL FGCVIAQVGV MDMLKFHKYT IGHAWTTDYG 
CSDSKQHFEW LVKYSPLHNV KLPEADDIQY PSMLLLTADH DDRVVPLHSL KFIATLQYIV 
GRSRKQSNPL LIHVDTKAGH GAGKPTAKVI EEVSDMFAFI ARCLNVDWIP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.