Details for: PRPSAP1
Gene ID: 5635
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: PRPSAP1
Ensembl ID: ENSG00000161542
Description: phosphoribosyl pyrophosphate synthetase associated protein 1
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 12.07rCSI 18.45%PRS 40.8
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CSI 10.64rCSI 12.77%PRS 34.88
-
CSI 10.51rCSI 26.59%PRS 43.87
-
CSI 10.44rCSI 8.48%PRS 37.34
-
CSI 6.06rCSI 12.88%PRS 43.17
-
CSI 5.65rCSI 8.01%PRS 34.13
-
CSI 5.57rCSI 12.33%PRS 33.85
-
CSI 5.32rCSI 5.12%PRS 37.17
-
CSI 5.11rCSI 8.58%PRS 23.41
-
CSI 4.56rCSI 7.25%PRS 30.9
-
CSI 4.4rCSI 3.65%PRS 37.19
-
CSI 4.34rCSI 3.22%PRS 48.93
-
CSI 4.14rCSI 6.54%PRS 37.21
-
CSI 3.91rCSI 3.13%PRS 57.32
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CSI 3.83rCSI 23.89%PRS 30.16
-
CSI 3.71rCSI 2.81%PRS 47.68
-
CSI 3.55rCSI 2.36%PRS 40.7
-
CSI 3.48rCSI 10.26%PRS 35.33
-
CSI 3.37rCSI 2.84%PRS 53.06
-
CSI 3.3rCSI 4.83%PRS 37.29
-
CSI 3.21rCSI 18.88%PRS 24.57
-
CSI 3.02rCSI 3.84%PRS 41.13
-
CSI 3rCSI 2.49%PRS 34.93
-
CSI 2.96rCSI 2.25%PRS 46.37
-
CSI 2.93rCSI 4.21%PRS 29.26
-
CSI 2.9rCSI 6.64%PRS 35.94
-
CSI 2.86rCSI 4.21%PRS 33.6
-
CSI 2.85rCSI 3.81%PRS 44.08
-
CSI 2.84rCSI 3.04%PRS 34.25
-
CSI 2.8rCSI 2.17%PRS 36.28
-
CSI 2.72rCSI 2.68%PRS 38.65
-
CSI 2.7rCSI 6.17%PRS 31.43
-
CSI 2.62rCSI 2.74%PRS 38.54
-
CSI 2.58rCSI 3.93%PRS 33.79
-
CSI 2.55rCSI 5.71%PRS 23.92
-
CSI 2.51rCSI 12.6%PRS 46.3
-
CSI 2.46rCSI 1.82%PRS 31.34
-
CSI 2.44rCSI 2.39%PRS 51.06
-
CSI 2.43rCSI 1.83%PRS 39.09
-
CSI 2.43rCSI 1.69%PRS 48.41
-
CSI 2.41rCSI 2.51%PRS 37.07
-
CSI 2.4rCSI 4.31%PRS 30.92
-
CSI 2.39rCSI 7.04%PRS 40.86
-
CSI 2.37rCSI 4.1%PRS 28.6
-
CSI 2.33rCSI 3.47%PRS 39.75
-
CSI 2.32rCSI 2.66%PRS 59.53
-
CSI 2.31rCSI 2.67%PRS 27.99
-
CSI 2.3rCSI 2.02%PRS 41.17
-
CSI 2.28rCSI 4.07%PRS 34.82
-
CSI 2.23rCSI 1.8%PRS 36.85
-
CSI 2.23rCSI 4.45%PRS 53.98
-
CSI 2.21rCSI 4.21%PRS 52.85
-
CSI 2.16rCSI 3.45%PRS 39.54
-
CSI 2.15rCSI 7.2%PRS 27.2
-
CSI 2.11rCSI 3.7%PRS 29.73
-
CSI 2.07rCSI 3.76%PRS 31.72
-
CSI 2.04rCSI 1.81%PRS 35.97
-
CSI 2.03rCSI 2.77%PRS 40.63
-
CSI 2.02rCSI 1.6%PRS 26.02
-
CSI 2.01rCSI 3.99%PRS 36.55
-
CSI 1.99rCSI 4%PRS 27.87
-
CSI 1.99rCSI 1.79%PRS 33.5
-
CSI 1.98rCSI 2.29%PRS 31.89
-
CSI 1.97rCSI 2.22%PRS 52.08
-
CSI 1.96rCSI 1.82%PRS 56.54
-
CSI 1.96rCSI 2.05%PRS 34.12
-
CSI 1.95rCSI 1.84%PRS 37.68
-
CSI 1.89rCSI 9.06%PRS 34.65
-
CSI 1.89rCSI 2.7%PRS 39.12
-
CSI 1.89rCSI 2.53%PRS 38.22
-
CSI 1.88rCSI 3.05%PRS 35.61
-
CSI 1.88rCSI 2.58%PRS 57.04
-
CSI 1.87rCSI 1.31%PRS 38.2
-
CSI 1.87rCSI 3.3%PRS 22.55
-
CSI 1.84rCSI 4.79%PRS 35.62
-
CSI 1.83rCSI 1.82%PRS 31.44
-
CSI 1.82rCSI 4.2%PRS 30.13
-
CSI 1.81rCSI 5.79%PRS 33.46
-
CSI 1.8rCSI 2.5%PRS 36.45
-
CSI 1.79rCSI 5.13%PRS 54.36
-
CSI 1.74rCSI 1.53%PRS 27.3
-
CSI 1.74rCSI 1.82%PRS 36.59
-
CSI 1.73rCSI 3.09%PRS 52.57
-
CSI 1.72rCSI 1.66%PRS 28.32
-
CSI 1.7rCSI 2.14%PRS 45.32
-
CSI 1.7rCSI 2.18%PRS 40.93
-
CSI 1.7rCSI 2.11%PRS 22.1
-
CSI 1.68rCSI 2.68%PRS 45.87
-
CSI 1.65rCSI 1.31%PRS 57.56
-
CSI 1.64rCSI 6.16%PRS 31.05
-
CSI 1.63rCSI 3.39%PRS 35.26
-
CSI 1.62rCSI 2.38%PRS 38.93
-
CSI 1.6rCSI 1.91%PRS 23.36
-
CSI 1.58rCSI 36.76%PRS 59.59
-
CSI 1.57rCSI 2.58%PRS 28.68
-
CSI 1.56rCSI 6.3%PRS 35.28
-
CSI 1.55rCSI 6.02%PRS 46.05
-
CSI 1.54rCSI 2.11%PRS 47.37
-
CSI 1.53rCSI 1.97%PRS 34.76
-
CSI 1.52rCSI 3.34%PRS 40.34
-
CSI 0.2rCSI 1.1%PRS 47.4%
-
CSI 0.2rCSI 5.3%PRS 23.7%
-
CSI 0.2rCSI 5.5%PRS 22.8%
-
CSI 0.3rCSI 5.3%PRS 30.7%
-
CSI 0.3rCSI 5.6%PRS 31.9%
-
CSI 0.3rCSI 2.1%PRS 26.1%
-
CSI 0.4rCSI 6.1%PRS 30.4%
-
CSI 0.5rCSI 1.4%PRS 24.4%
-
CSI 0.5rCSI 0.9%PRS 52.2%
-
CSI 0.5rCSI 1.2%PRS 33.9%
-
CSI 0.5rCSI 3.3%PRS 56.5%
-
CSI 0.6rCSI 2.8%PRS 47.0%
-
CSI 0.6rCSI 3.2%PRS 24.9%
-
CSI 0.6rCSI 2.6%PRS 35.1%
-
CSI 0.6rCSI 2.1%PRS 22.4%
-
CSI 0.6rCSI 1.8%PRS 39.3%
-
CSI 0.6rCSI 1.5%PRS 22.7%
-
CSI 0.6rCSI 1.6%PRS 28.7%
-
CSI 0.8rCSI 2.2%PRS 51.6%
-
CSI 0.8rCSI 1.7%PRS 26.9%
-
CSI 0.8rCSI 1.3%PRS 34.6%
-
CSI 0.9rCSI 2.1%PRS 68.5%
-
CSI 0.9rCSI 1.7%PRS 37.9%
-
CSI 0.9rCSI 17.3%PRS 65.3%
-
CSI 0.9rCSI 3.4%PRS 32.2%
-
CSI 0.9rCSI 3.2%PRS 30.5%
-
CSI 0.9rCSI 0.7%PRS 34.8%
-
CSI 0.9rCSI 3.0%PRS 44.9%
-
CSI 1.0rCSI 1.2%PRS 32.8%
-
CSI 1.0rCSI 2.2%PRS 35.7%
-
CSI 1.0rCSI 1.9%PRS 60.2%
-
CSI 1.1rCSI 3.7%PRS 52.6%
-
CSI 1.1rCSI 1.5%PRS 49.2%
-
CSI 1.1rCSI 1.4%PRS 24.2%
-
CSI 1.1rCSI 4.2%PRS 24.3%
-
CSI 1.2rCSI 3.3%PRS 31.0%
-
CSI 1.3rCSI 3.5%PRS 34.2%
-
CSI 1.3rCSI 1.5%PRS 40.2%
-
CSI 1.3rCSI 3.0%PRS 56.2%
-
CSI 1.3rCSI 2.1%PRS 28.7%
-
CSI 1.3rCSI 3.2%PRS 42.4%
-
CSI 1.4rCSI 2.1%PRS 36.8%
-
CSI 1.4rCSI 2.0%PRS 46.6%
-
CSI 1.4rCSI 4.4%PRS 26.4%
-
CSI 1.4rCSI 2.6%PRS 27.9%
-
CSI 1.4rCSI 4.1%PRS 37.3%
-
CSI 1.4rCSI 2.3%PRS 25.3%
-
CSI 1.4rCSI 2.0%PRS 31.4%
-
CSI 1.5rCSI 6.5%PRS 31.5%
-
CSI 1.5rCSI 2.4%PRS 31.4%
-
CSI 1.5rCSI 2.3%PRS 37.7%
-
CSI 1.5rCSI 3.3%PRS 40.3%
-
CSI 1.5rCSI 2.0%PRS 34.8%
-
CSI 1.5rCSI 2.1%PRS 47.4%
-
CSI 1.6rCSI 6.0%PRS 46.1%
-
CSI 1.6rCSI 6.3%PRS 35.3%
-
CSI 1.6rCSI 2.6%PRS 28.7%
-
CSI 1.6rCSI 36.8%PRS 59.6%
-
CSI 1.6rCSI 1.9%PRS 23.4%
-
CSI 1.6rCSI 2.4%PRS 38.9%
-
CSI 1.6rCSI 3.4%PRS 35.3%
-
CSI 1.6rCSI 6.2%PRS 31.1%
-
CSI 1.7rCSI 1.3%PRS 57.6%
-
CSI 1.7rCSI 2.7%PRS 45.9%
-
CSI 1.7rCSI 2.1%PRS 22.1%
-
CSI 1.7rCSI 2.2%PRS 40.9%
-
CSI 1.7rCSI 2.1%PRS 45.3%
-
CSI 1.7rCSI 1.7%PRS 28.3%
-
CSI 1.7rCSI 3.1%PRS 52.6%
-
CSI 1.7rCSI 1.8%PRS 36.6%
-
CSI 1.7rCSI 1.5%PRS 27.3%
-
CSI 1.8rCSI 5.1%PRS 54.4%
-
CSI 1.8rCSI 2.5%PRS 36.5%
-
CSI 1.8rCSI 5.8%PRS 33.5%
-
CSI 1.8rCSI 4.2%PRS 30.1%
-
CSI 1.8rCSI 1.8%PRS 31.4%
-
CSI 1.8rCSI 4.8%PRS 35.6%
-
CSI 1.9rCSI 3.3%PRS 22.6%
-
CSI 1.9rCSI 1.3%PRS 38.2%
-
CSI 1.9rCSI 2.6%PRS 57.0%
-
CSI 1.9rCSI 3.1%PRS 35.6%
-
CSI 1.9rCSI 2.5%PRS 38.2%
-
CSI 1.9rCSI 2.7%PRS 39.1%
-
CSI 1.9rCSI 9.1%PRS 34.7%
-
CSI 2.0rCSI 1.8%PRS 37.7%
-
CSI 2.0rCSI 2.1%PRS 34.1%
-
CSI 2.0rCSI 1.8%PRS 56.5%
-
CSI 2.0rCSI 2.2%PRS 52.1%
-
CSI 2.0rCSI 2.3%PRS 31.9%
-
CSI 2.0rCSI 1.8%PRS 33.5%
-
CSI 2.0rCSI 4.0%PRS 27.9%
-
CSI 2.0rCSI 4.0%PRS 36.6%
-
CSI 2.0rCSI 1.6%PRS 26.0%
-
CSI 2.0rCSI 2.8%PRS 40.6%
-
CSI 2.0rCSI 1.8%PRS 36.0%
-
CSI 2.1rCSI 3.8%PRS 31.7%
-
CSI 2.1rCSI 3.7%PRS 29.7%
-
CSI 2.2rCSI 7.2%PRS 27.2%
-
CSI 2.2rCSI 3.5%PRS 39.5%
-
CSI 2.2rCSI 4.2%PRS 52.9%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 3662273680
Symbol: KPRA_HUMAN
Name: Phosphoribosyl pyrophosphate synthase-associated protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8611620
Title: Cloning and sequencing of human complementary DNA for the phosphoribosylpyrophosphate synthetase-associated protein 39.
PubMed ID: 8611620
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 356
- Mass: 39394
- Checksum: 38CC87AB2C555717
- Sequence:
MNAARTGYRV FSANSTAACT ELAKRITERL GAELGKSVVY QETNGETRVE IKESVRGQDI FIIQTIPRDV NTAVMELLIM AYALKTACAR NIIGVIPYFP YSKQSKMRKR GSIVCKLLAS MLAKAGLTHI ITMDLHQKEI QGFFSFPVDN LRASPFLLQY IQEEIPNYRN AVIVAKSPDA AKRAQSYAER LRLGLAVIHG EAQCTELDMD DGRHSPPMVK NATVHPGLEL PLMMAKEKPP ITVVGDVGGR IAIIVDDIID DVESFVAAAE ILKERGAYKI YVMATHGILS AEAPRLIEES SVDEVVVTNT VPHEVQKLQC PKIKTVDISL ILSEAIRRIH NGESMAYLFR NITVDD
Genular Protein ID: 674819129
Symbol: B4DP31_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 282
- Mass: 31266
- Checksum: 51832844BF1BF011
- Sequence:
MELLIMAYAL KTACARNIIG VIPYFPYSKQ SKMRKRGSIV CKLLASMLAK AGLTHIITMD LHQKEIQGFF SFPVDNLRAS PFLLQYIQEE IPNYRNAVIV AKSPDAAKRA QSYAERLRLG LAVIHGEAQC TELDMDDGRH SPPMVKNATV HPGLELPLMM AKEKPPITVV GDVGGRIAII VDDIIDDVES FVAAAEILKE RGAYKIYVMA THGILSAEAP RLIEESSVDE VVVTNTVPHE VQKLQCPKIK TVDISLILSE AIRRIHNGES MAYLFRNITV DD