Details for: PVR

Gene ID: 5817

Symbol: PVR

Ensembl ID: ENSG00000073008

Description: PVR cell adhesion molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 92.5776
    Cell Significance Index: -14.4000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 56.2995
    Cell Significance Index: -14.2800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 29.9810
    Cell Significance Index: -12.1800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 12.7783
    Cell Significance Index: -12.2000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 11.8009
    Cell Significance Index: -14.5500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.6974
    Cell Significance Index: -14.5900
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 1.6410
    Cell Significance Index: 18.9000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.2383
    Cell Significance Index: 33.1800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1421
    Cell Significance Index: 112.9800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1155
    Cell Significance Index: 181.4200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.0861
    Cell Significance Index: 23.5300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0563
    Cell Significance Index: 953.7500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.0265
    Cell Significance Index: 295.3600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.9737
    Cell Significance Index: 14.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8202
    Cell Significance Index: 22.3300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7657
    Cell Significance Index: 83.2900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7287
    Cell Significance Index: 21.0000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.7268
    Cell Significance Index: 11.6600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6849
    Cell Significance Index: 52.5600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6775
    Cell Significance Index: 30.7100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6600
    Cell Significance Index: 132.4000
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.6405
    Cell Significance Index: 4.6000
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.6116
    Cell Significance Index: 6.1700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4862
    Cell Significance Index: 96.4800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4441
    Cell Significance Index: 30.7200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4399
    Cell Significance Index: 157.7900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.3730
    Cell Significance Index: 232.9100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.3491
    Cell Significance Index: 5.8800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.2579
    Cell Significance Index: 2.6700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2015
    Cell Significance Index: 38.3500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1772
    Cell Significance Index: 6.2300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1656
    Cell Significance Index: 20.3700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.1449
    Cell Significance Index: 2.5600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1343
    Cell Significance Index: 22.9400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.1321
    Cell Significance Index: 1.9000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1288
    Cell Significance Index: 16.6400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1103
    Cell Significance Index: 2.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1058
    Cell Significance Index: 57.8000
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0926
    Cell Significance Index: 1.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0815
    Cell Significance Index: 3.8000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0636
    Cell Significance Index: 8.7300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0346
    Cell Significance Index: 23.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0306
    Cell Significance Index: 5.5300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0301
    Cell Significance Index: 1.4200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0300
    Cell Significance Index: 1.5600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0217
    Cell Significance Index: 2.4800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0195
    Cell Significance Index: 8.6200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0100
    Cell Significance Index: 0.6200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0084
    Cell Significance Index: 12.9400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0073
    Cell Significance Index: 13.5500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0028
    Cell Significance Index: 5.1800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0019
    Cell Significance Index: 2.5900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0012
    Cell Significance Index: 0.5600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0002
    Cell Significance Index: 0.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0002
    Cell Significance Index: 0.1300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0020
    Cell Significance Index: -1.5100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0032
    Cell Significance Index: -0.4600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0082
    Cell Significance Index: -5.2300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0098
    Cell Significance Index: -5.5500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0115
    Cell Significance Index: -1.4800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0125
    Cell Significance Index: -0.1700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0133
    Cell Significance Index: -0.2200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0134
    Cell Significance Index: -9.8300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0287
    Cell Significance Index: -6.0400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0309
    Cell Significance Index: -3.5500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0354
    Cell Significance Index: -3.6200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0374
    Cell Significance Index: -2.1000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0396
    Cell Significance Index: -4.6200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0523
    Cell Significance Index: -2.6400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0541
    Cell Significance Index: -0.9100
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0545
    Cell Significance Index: -0.3600
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.0718
    Cell Significance Index: -0.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0732
    Cell Significance Index: -5.1800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0786
    Cell Significance Index: -4.1000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0867
    Cell Significance Index: -1.2800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1253
    Cell Significance Index: -1.8000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1257
    Cell Significance Index: -13.0900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1263
    Cell Significance Index: -14.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1308
    Cell Significance Index: -8.2500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1397
    Cell Significance Index: -3.0600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1398
    Cell Significance Index: -9.4000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1419
    Cell Significance Index: -7.4500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1481
    Cell Significance Index: -4.7500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1558
    Cell Significance Index: -1.7700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1559
    Cell Significance Index: -4.1000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1574
    Cell Significance Index: -4.4000
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.1575
    Cell Significance Index: -1.6300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1689
    Cell Significance Index: -13.3800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1843
    Cell Significance Index: -3.7000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1845
    Cell Significance Index: -5.2900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1902
    Cell Significance Index: -11.6600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1902
    Cell Significance Index: -6.6100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2107
    Cell Significance Index: -4.4100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2157
    Cell Significance Index: -9.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2225
    Cell Significance Index: -14.3600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2239
    Cell Significance Index: -7.1300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2243
    Cell Significance Index: -4.7600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2260
    Cell Significance Index: -5.4200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2319
    Cell Significance Index: -5.0100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2443
    Cell Significance Index: -8.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cell Surface Expression:** PVR is a transmembrane protein expressed on the surface of cells, where it interacts with other cell adhesion molecules to form heterophilic complexes. 2. **Adherens Junction Formation:** PVR plays a critical role in the formation of adherens junctions, which are essential for maintaining tissue structure and facilitating cell-cell communication. 3. **Nectin/Necl Trans-Heterodimerization:** PVR interacts with other nectin family members, such as Necl1, to form heterodimers that regulate cell-cell adhesion and signaling. 4. **Immune Regulation:** PVR is involved in the regulation of immune responses, including the modulation of natural killer cell and T cell-mediated cytotoxicity. 5. **Tissue-Specific Expression:** PVR is expressed in various tissues, including the immune system, the nervous system, and the epithelial lining of the gut. **Pathways and Functions:** 1. **Adaptive Immune System:** PVR is involved in the regulation of immune responses, including the modulation of natural killer cell and T cell-mediated cytotoxicity. 2. **Cell-Cell Communication:** PVR facilitates cell-cell communication by forming adherens junctions and heterophilic interactions with other cell adhesion molecules. 3. **Cytoskeleton Organization:** PVR regulates the organization of the cytoskeleton, which is essential for maintaining tissue structure and facilitating cell movement. 4. **Signaling Pathways:** PVR activates signaling pathways that regulate cell growth, differentiation, and survival. 5. **Susceptibility to Natural Killer Cell-Mediated Cytotoxicity:** PVR is involved in the regulation of susceptibility to natural killer cell-mediated cytotoxicity. **Clinical Significance:** 1. **Cancer Therapy:** PVR has been identified as a potential target for cancer therapy, as it is involved in the regulation of immune responses and the evasion of immune surveillance by tumor cells. 2. **Autoimmune Diseases:** PVR may play a role in the pathogenesis of autoimmune diseases, such as multiple sclerosis, where it is involved in the regulation of immune responses and the formation of adherens junctions. 3. **Neurological Disorders:** PVR has been implicated in the pathogenesis of neurological disorders, such as Alzheimer's disease, where it is involved in the regulation of cell-cell communication and the organization of the cytoskeleton. 4. **Infectious Diseases:** PVR may play a role in the pathogenesis of infectious diseases, such as poliovirus infection, where it is involved in the entry of the virus into host cells. In conclusion, the PVR cell adhesion molecule is a critical component of the immune system, playing a significant role in cell-cell interactions, immune regulation, and the modulation of immune responses. Further research is needed to fully understand the role of PVR in various diseases and to identify potential therapeutic targets for the treatment of these conditions.

Genular Protein ID: 3478296459

Symbol: PVR_HUMAN

Name: Poliovirus receptor

UniProtKB Accession Codes:

P15151 B4DTS9 P15152 Q15267 Q15268 Q96BJ1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 3 CPTC 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 28 EMDB 3 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PIR 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 2 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2538245

Title: Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily.

PubMed ID: 2538245

DOI: 10.1016/0092-8674(89)90690-9

PubMed ID: 2170108

Title: The poliovirus receptor protein is produced both as membrane-bound and secreted forms.

PubMed ID: 2170108

DOI: 10.1002/j.1460-2075.1990.tb07520.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1851992

Title: Functional domains of the poliovirus receptor.

PubMed ID: 1851992

DOI: 10.1073/pnas.88.10.4104

PubMed ID: 1331527

Title: N glycosylation of the virus binding domain is not essential for function of the human poliovirus receptor.

PubMed ID: 1331527

DOI: 10.1128/jvi.66.12.7368-7373.1992

PubMed ID: 9616127

Title: Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor.

PubMed ID: 9616127

DOI: 10.1126/science.280.5369.1618

PubMed ID: 11437656

Title: The poliovirus receptor CD155 mediates cell-to-matrix contacts by specifically binding to vitronectin.

PubMed ID: 11437656

DOI: 10.1006/viro.2001.0943

PubMed ID: 11751937

Title: Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis.

PubMed ID: 11751937

DOI: 10.1074/jbc.m111937200

PubMed ID: 11983699

Title: Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog.

PubMed ID: 11983699

DOI: 10.1074/jbc.m201378200

PubMed ID: 12759359

Title: Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains.

PubMed ID: 12759359

DOI: 10.1074/jbc.m304166200

PubMed ID: 15194502

Title: Ligand stimulation of CD155alpha inhibits cell adhesion and enhances cell migration in fibroblasts.

PubMed ID: 15194502

DOI: 10.1016/j.bbrc.2004.05.111

PubMed ID: 15039383

Title: Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112).

PubMed ID: 15039383

DOI: 10.1093/intimm/dxh059

PubMed ID: 15194795

Title: Receptor (CD155)-dependent endocytosis of poliovirus and retrograde axonal transport of the endosome.

PubMed ID: 15194795

DOI: 10.1128/jvi.78.13.7186-7198.2004

PubMed ID: 15471548

Title: CD155/PVR plays a key role in cell motility during tumor cell invasion and migration.

PubMed ID: 15471548

DOI: 10.1186/1471-2407-4-73

PubMed ID: 16216929

Title: Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3.

PubMed ID: 16216929

DOI: 10.1083/jcb.200501090

PubMed ID: 15034010

Title: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155).

PubMed ID: 15034010

DOI: 10.4049/jimmunol.172.7.3994

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 15607800

Title: PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis.

PubMed ID: 15607800

DOI: 10.1016/j.molimm.2004.07.028

PubMed ID: 15640804

Title: Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141.

PubMed ID: 15640804

DOI: 10.1038/ni1156

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19011627

Title: The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

PubMed ID: 19011627

DOI: 10.1038/ni.1674

PubMed ID: 22171320

Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.

PubMed ID: 22171320

DOI: 10.1074/mcp.m111.013649

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 10618374

Title: Interaction of the poliovirus receptor with poliovirus.

PubMed ID: 10618374

DOI: 10.1073/pnas.97.1.79

PubMed ID: 12663789

Title: Complexes of poliovirus serotypes with their common cellular receptor, CD155.

PubMed ID: 12663789

DOI: 10.1128/jvi.77.8.4827-4835.2003

PubMed ID: 22421438

Title: Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.

PubMed ID: 22421438

DOI: 10.1073/pnas.1120606109

Sequence Information:

  • Length: 417
  • Mass: 45303
  • Checksum: D15C012CE853169B
  • Sequence:
    • MARAMAAAWP LLLVALLVLS WPPPGTGDVV VQAPTQVPGF LGDSVTLPCY LQVPNMEVTH 
VSQLTWARHG ESGSMAVFHQ TQGPSYSESK RLEFVAARLG AELRNASLRM FGLRVEDEGN 
YTCLFVTFPQ GSRSVDIWLR VLAKPQNTAE VQKVQLTGEP VPMARCVSTG GRPPAQITWH 
SDLGGMPNTS QVPGFLSGTV TVTSLWILVP SSQVDGKNVT CKVEHESFEK PQLLTVNLTV 
YYPPEVSISG YDNNWYLGQN EATLTCDARS NPEPTGYNWS TTMGPLPPFA VAQGAQLLIR 
PVDKPINTTL ICNVTNALGA RQAELTVQVK EGPPSEHSGI SRNAIIFLVL GILVFLILLG 
IGIYFYWSKC SREVLWHCHL CPSSTEHASA SANGHVSYSA VSRENSSSQD PQTEGTR

Genular Protein ID: 2403361679

Symbol: A0A0C4DG49_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DG49

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 HGNC 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 2 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 417
  • Mass: 45321
  • Checksum: D636ACECE856078F
  • Sequence:
    • MARAMAAAWP LLLVALLVLS WPPPGTGDVV VQAPTQVPGF LGDSVTLPCY LQVPNMEVTH 
VSQLTWARHG ESGSMAVFHQ TQGPSYSESK RLEFVAARLG AELRNASLRM FGLRVEDEGN 
YTCLFVTFPQ GSRSVDIWLR VLAKPQNTAE VQKVQLTGEP VPMARCVSTG GRPPAQITWH 
SDLGGMPNTS QVPGFLSGTV TVTSLWILVP SSQVDGKNVT CKVEHESFEK PQLLTVNLTV 
YYPPEVSISG YDNNWYLGQN EATLTCDARS NPEPTGYNWS TTMGPLPPFA VAQGAQLLIR 
PVDKPINTTL ICNVTNALGA RQAELTVQVK EGPPSEHSGM SRNAIIFLVL GILVFLILLG 
IGIYFYWSKC SREVLWHCHL CPSSTEHASA SANGHVSYSA VSRENSSSQD PQTEGTR

Genular Protein ID: 1609619443

Symbol: A0A0A0MSA9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MSA9

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 392
  • Mass: 42882
  • Checksum: E68DFC93B0271269
  • Sequence:
    • MARAMAAAWP LLLVALLVLS WPPPGTGDVV VQAPTQVPGF LGDSVTLPCY LQVPNMEVTH 
VSQLTWARHG ESGSMAVFHQ TQGPSYSESK RLEFVAARLG AELRNASLRM FGLRVEDEGN 
YTCLFVTFPQ GSRSVDIWLR VLAKPQNTAE VQKVQLTGEP VPMARCVSTG GRPPAQITWH 
SDLGGMPNTS QVPGFLSGTV TVTSLWILVP SSQVDGKNVT CKVEHESFEK PQLLTVNLTV 
YYPPEVSISG YDNNWYLGQN EATLTCDARS NPEPTGYNWS TTMGPLPPFA VAQGAQLLIR 
PVDKPINTTL ICNVTNALGA RQAELTVQVK EGPPSEHSGM SRNAIIFLVL GILVFLILLG 
IGIYFYWSKC SREVLWHCHL CPSSEHHQSC RN

Genular Protein ID: 561783280

Symbol: A8K4I1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K4I1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 417
  • Mass: 45379
  • Checksum: A4A77CEC2757188F
  • Sequence:
    • MARAMAAAWP LLLVALLVLS WPPPGTGDVV VQAPTQVPGF LDDSVTLPCY LQVPNMEVTH 
VSQLTWARHG ESGSMAVFHQ TQGPSYSESK RLEFVAARLG AELRNASLRM FGLRVEDEGN 
YTCLFVTFPQ GSRSVDIWLR VLAKPQNTAE VQKVQLTGEP VPMARCVSTG GRPPAQITWH 
SDLGGMPNTS QVPGFLSGTV TVTSLWILVP SSQVDGKNVT CKVEHESFEK PQLLTVNLTV 
YYPPEVSISG YDNNWYLGQN EATLTCDARS NPEPTGYNWS TTMGPLPPFA VAQGAQLLIR 
PVDKPINTTL ICNVTNALGA RQAELTVQVK EGPPSEHSGM SRNAIIFLVL GILVFLILLG 
IGIYFYWSKC SREVLWHCHL CPSSTEHASA SANGHVSYSA VSRENSSSQD PQTEGTR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.