Details for: MAP4K2

Gene ID: 5871

Symbol: MAP4K2

Ensembl ID: ENSG00000168067

Description: mitogen-activated protein kinase kinase kinase kinase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 74.9943
    Cell Significance Index: -11.6700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 35.0492
    Cell Significance Index: -8.8900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 31.6545
    Cell Significance Index: -13.0400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 29.5133
    Cell Significance Index: -11.9900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 26.0700
    Cell Significance Index: -13.4100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 12.8071
    Cell Significance Index: -12.2300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.4934
    Cell Significance Index: -11.7100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.8267
    Cell Significance Index: -12.9300
  • Cell Name: centroblast (CL0009112)
    Fold Change: 3.5447
    Cell Significance Index: 8.2700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.4707
    Cell Significance Index: -10.6600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.0512
    Cell Significance Index: -12.0400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.8877
    Cell Significance Index: -6.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.0661
    Cell Significance Index: 125.7300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.8245
    Cell Significance Index: 42.9500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6546
    Cell Significance Index: 42.2300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5516
    Cell Significance Index: 54.5600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.4774
    Cell Significance Index: 14.0200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4757
    Cell Significance Index: 10.1300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4186
    Cell Significance Index: 289.5000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4011
    Cell Significance Index: 362.1800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.3673
    Cell Significance Index: 9.8300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2866
    Cell Significance Index: 31.1800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2707
    Cell Significance Index: 44.0200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2547
    Cell Significance Index: 15.2900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2438
    Cell Significance Index: 48.9000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2353
    Cell Significance Index: 6.3100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1869
    Cell Significance Index: 2.5500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1606
    Cell Significance Index: 10.1200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1407
    Cell Significance Index: 16.4000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1122
    Cell Significance Index: 7.7600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0769
    Cell Significance Index: 27.5700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0748
    Cell Significance Index: 14.2400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0616
    Cell Significance Index: 12.2200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0604
    Cell Significance Index: 1.7400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0513
    Cell Significance Index: 7.0400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0478
    Cell Significance Index: 2.2300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0474
    Cell Significance Index: 8.5500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0447
    Cell Significance Index: 0.2700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0417
    Cell Significance Index: 5.1300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0311
    Cell Significance Index: 1.6400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0286
    Cell Significance Index: 3.6600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0267
    Cell Significance Index: 11.8000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0246
    Cell Significance Index: 13.4400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0183
    Cell Significance Index: 0.8300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0171
    Cell Significance Index: 0.3700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0110
    Cell Significance Index: 20.6400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0052
    Cell Significance Index: 3.3100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0049
    Cell Significance Index: 9.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0048
    Cell Significance Index: 0.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0041
    Cell Significance Index: 6.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0050
    Cell Significance Index: -6.7800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0099
    Cell Significance Index: -7.2400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0126
    Cell Significance Index: -5.7300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0134
    Cell Significance Index: -9.9200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0143
    Cell Significance Index: -10.8500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0202
    Cell Significance Index: -11.4200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0217
    Cell Significance Index: -3.1500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0221
    Cell Significance Index: -13.7900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0334
    Cell Significance Index: -2.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0372
    Cell Significance Index: -10.7000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0388
    Cell Significance Index: -6.6300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0445
    Cell Significance Index: -1.2700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0456
    Cell Significance Index: -4.6600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0456
    Cell Significance Index: -2.3700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0491
    Cell Significance Index: -0.4000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0630
    Cell Significance Index: -13.2600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0640
    Cell Significance Index: -1.7100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0656
    Cell Significance Index: -8.4800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0699
    Cell Significance Index: -8.0100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0700
    Cell Significance Index: -4.9500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0825
    Cell Significance Index: -6.1500
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0885
    Cell Significance Index: -1.1800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0891
    Cell Significance Index: -2.4900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1045
    Cell Significance Index: -10.8800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1059
    Cell Significance Index: -4.9800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1068
    Cell Significance Index: -2.6700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1092
    Cell Significance Index: -6.7100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1124
    Cell Significance Index: -6.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1132
    Cell Significance Index: -7.6100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1201
    Cell Significance Index: -2.2200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1213
    Cell Significance Index: -3.1000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1293
    Cell Significance Index: -5.7200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1315
    Cell Significance Index: -3.5800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1326
    Cell Significance Index: -2.7500
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.1516
    Cell Significance Index: -1.5200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1517
    Cell Significance Index: -2.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1542
    Cell Significance Index: -12.2100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1582
    Cell Significance Index: -5.9900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1757
    Cell Significance Index: -9.8600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1808
    Cell Significance Index: -5.7900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2085
    Cell Significance Index: -3.4900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2276
    Cell Significance Index: -7.9100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2364
    Cell Significance Index: -3.4000
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.2366
    Cell Significance Index: -2.9900
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.2367
    Cell Significance Index: -4.0800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2424
    Cell Significance Index: -2.8900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2425
    Cell Significance Index: -5.3100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2458
    Cell Significance Index: -3.5200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2540
    Cell Significance Index: -8.3200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2554
    Cell Significance Index: -6.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Serine/threonine kinase activity**: MAP4K2 possesses serine/threonine kinase activity, allowing it to phosphorylate and regulate the activity of downstream targets. 2. **MAP kinase kinase kinase kinase activity**: MAP4K2 is a member of the MAP kinase kinase kinase kinase family, which is involved in the regulation of multiple signaling pathways. 3. **High expression in immune cells**: MAP4K2 is highly expressed in cells of the immune system, including B cells, T cells, and germinal center B cells. 4. **Expression in neural cells**: MAP4K2 is also expressed in cells of the nervous system, including GABAergic interneurons and radial glial cells. **Pathways and Functions:** 1. **JNK cascade**: MAP4K2 is involved in the regulation of the JNK cascade, a signaling pathway that plays a critical role in cell survival, differentiation, and apoptosis. 2. **Regulation of Jun kinase activity**: MAP4K2 regulates the activity of Jun kinase, a transcription factor that plays a key role in cell proliferation, differentiation, and survival. 3. **Innate immune response**: MAP4K2 is involved in the regulation of the innate immune response, including the activation of immune cells and the production of cytokines. 4. **Vesicle targeting**: MAP4K2 is involved in the regulation of vesicle targeting and trafficking, which is critical for the delivery of proteins and lipids to specific cellular compartments. **Clinical Significance:** 1. **Autoimmune diseases**: MAP4K2 may play a role in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and lupus, by regulating the activity of immune cells and the production of cytokines. 2. **Neurodegenerative disorders**: MAP4K2 may be involved in the pathogenesis of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, by regulating the activity of neural cells and the production of neurotrophic factors. 3. **Cancer**: MAP4K2 may play a role in the development and progression of cancer by regulating the activity of cell signaling pathways and the production of growth factors. 4. **Therapeutic potential**: Targeting MAP4K2 may provide a novel therapeutic strategy for the treatment of autoimmune diseases, neurodegenerative disorders, and cancer. In conclusion, MAP4K2 is a multifaceted gene that plays a critical role in various cellular processes, including immune response, cell signaling, and vesicle targeting. Its clinical significance lies in its potential role in the pathogenesis of autoimmune diseases, neurodegenerative disorders, and cancer. Further research is needed to fully understand the role of MAP4K2 in human disease and to explore its therapeutic potential.

Genular Protein ID: 3615115097

Symbol: M4K2_HUMAN

Name: Mitogen-activated protein kinase kinase kinase kinase 2

UniProtKB Accession Codes:

Q12851 Q86VU3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 4 CTD 1 ChEBI 13 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 2 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 Rhea 6 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7515885

Title: Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center.

PubMed ID: 7515885

DOI: 10.1016/s0021-9258(19)89463-2

PubMed ID: 7477268

Title: Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase.

PubMed ID: 7477268

DOI: 10.1038/377750a0

PubMed ID: 9712898

Title: Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38.

PubMed ID: 9712898

DOI: 10.1074/jbc.273.35.22681

PubMed ID: 11784851

Title: Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

PubMed ID: 11784851

DOI: 10.1128/mcb.22.3.737-749.2002

PubMed ID: 15456887

Title: Germinal center kinase is required for optimal Jun N-terminal kinase activation by Toll-like receptor agonists and is regulated by the ubiquitin proteasome system and agonist-induced, TRAF6-dependent stabilization.

PubMed ID: 15456887

DOI: 10.1128/mcb.24.20.9165-9175.2004

PubMed ID: 17584736

Title: Dissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine release.

PubMed ID: 17584736

DOI: 10.1074/jbc.m703422200

PubMed ID: 10026130

Title: Signaling by the germinal center kinase family of protein kinases.

PubMed ID: 10026130

DOI: 10.1074/jbc.274.9.5259

PubMed ID: 11316611

Title: The Ste20 group kinases as regulators of MAP kinase cascades.

PubMed ID: 11316611

DOI: 10.1016/s0962-8924(01)01980-8

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26437443

Title: MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway.

PubMed ID: 26437443

DOI: 10.1038/ncomms9357

Sequence Information:

  • Length: 820
  • Mass: 91556
  • Checksum: A59C1E99BFFAEF41
  • Sequence:
    • MALLRDVSLQ DPRDRFELLQ RVGAGTYGDV YKARDTVTSE LAAVKIVKLD PGDDISSLQQ 
EITILRECRH PNVVAYIGSY LRNDRLWICM EFCGGGSLQE IYHATGPLEE RQIAYVCREA 
LKGLHHLHSQ GKIHRDIKGA NLLLTLQGDV KLADFGVSGE LTASVAKRRS FIGTPYWMAP 
EVAAVERKGG YNELCDVWAL GITAIELGEL QPPLFHLHPM RALMLMSKSS FQPPKLRDKT 
RWTQNFHHFL KLALTKNPKK RPTAEKLLQH PFTTQQLPRA LLTQLLDKAS DPHLGTPSPE 
DCELETYDMF PDTIHSRGQH GPAERTPSEI QFHQVKFGAP RRKETDPLNE PWEEEWTLLG 
KEELSGSLLQ SVQEALEERS LTIRSASEFQ ELDSPDDTMG TIKRAPFLGP LPTDPPAEEP 
LSSPPGTLPP PPSGPNSSPL LPTAWATMKQ REDPERSSCH GLPPTPKVHM GACFSKVFNG 
CPLRIHAAVT WIHPVTRDQF LVVGAEEGIY TLNLHELHED TLEKLISHRC SWLYCVNNVL 
LSLSGKSTHI WAHDLPGLFE QRRLQQQVPL SIPTNRLTQR IIPRRFALST KIPDTKGCLQ 
CRVVRNPYTG ATFLLAALPT SLLLLQWYEP LQKFLLLKNF SSPLPSPAGM LEPLVLDGKE 
LPQVCVGAEG PEGPGCRVLF HVLPLEAGLT PDILIPPEGI PGSAQQVIQV DRDTILVSFE 
RCVRIVNMQG EPTATLAPEL TFDFPIETVV CLQDSVLAFW SHGMQGRSLD TNEVTQEITD 
ETRIFRVLGA HRDIILESIP TDNPEAHSNL YILTGHQSTY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.