Details for: RAD51D
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 79.4624
Cell Significance Index: -12.3600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 44.3536
Cell Significance Index: -11.2500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 10.7871
Cell Significance Index: -13.3000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 4.9424
Cell Significance Index: -13.2400 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.5386
Cell Significance Index: -13.9400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.4237
Cell Significance Index: -13.5100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.9955
Cell Significance Index: 189.4600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.9695
Cell Significance Index: 194.4900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8383
Cell Significance Index: 82.9300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.6068
Cell Significance Index: 36.4300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4920
Cell Significance Index: 53.5100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4864
Cell Significance Index: 174.4800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4163
Cell Significance Index: 67.7000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4085
Cell Significance Index: 18.0700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.3964
Cell Significance Index: 15.0100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3893
Cell Significance Index: 269.2500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3878
Cell Significance Index: 350.1500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.1919
Cell Significance Index: 9.7000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1881
Cell Significance Index: 13.0100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1775
Cell Significance Index: 11.4500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1690
Cell Significance Index: 23.2100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1613
Cell Significance Index: 9.0500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1461
Cell Significance Index: 4.2100 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.1361
Cell Significance Index: 2.9100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.1199
Cell Significance Index: 34.4900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1106
Cell Significance Index: 8.4900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1096
Cell Significance Index: 4.9700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1029
Cell Significance Index: 2.2300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0904
Cell Significance Index: 16.2900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0766
Cell Significance Index: 33.8700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0611
Cell Significance Index: 7.1200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.0501
Cell Significance Index: 1.3400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0491
Cell Significance Index: 26.8400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0389
Cell Significance Index: 2.3900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0280
Cell Significance Index: 3.4400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0239
Cell Significance Index: 2.8200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0001
Cell Significance Index: 0.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0072
Cell Significance Index: -13.5100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0095
Cell Significance Index: -6.9800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0129
Cell Significance Index: -9.7700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0139
Cell Significance Index: -10.3100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0183
Cell Significance Index: -10.3400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0194
Cell Significance Index: -12.2900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0230
Cell Significance Index: -0.4900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0271
Cell Significance Index: -1.4100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0315
Cell Significance Index: -14.3000 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0330
Cell Significance Index: -4.2300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0390
Cell Significance Index: -6.6600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0443
Cell Significance Index: -5.7200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0471
Cell Significance Index: -4.8100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0480
Cell Significance Index: -1.6900 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0540
Cell Significance Index: -1.3800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0634
Cell Significance Index: -2.0300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0667
Cell Significance Index: -4.7200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0740
Cell Significance Index: -1.6200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0740
Cell Significance Index: -8.4800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0743
Cell Significance Index: -3.4900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0778
Cell Significance Index: -16.3900 - Cell Name: medium spiny neuron (CL1001474)
Fold Change: -0.0778
Cell Significance Index: -1.0500 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.0792
Cell Significance Index: -1.3700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0848
Cell Significance Index: -12.3200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0906
Cell Significance Index: -6.7500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0924
Cell Significance Index: -4.8500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1111
Cell Significance Index: -7.0000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1297
Cell Significance Index: -2.1700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1324
Cell Significance Index: -8.1200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1440
Cell Significance Index: -3.9200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1460
Cell Significance Index: -11.5600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1494
Cell Significance Index: -5.1900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1719
Cell Significance Index: -4.5900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2312
Cell Significance Index: -6.7900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2314
Cell Significance Index: -6.2000 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.2322
Cell Significance Index: -3.3400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2449
Cell Significance Index: -6.4400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2668
Cell Significance Index: -4.0200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.2788
Cell Significance Index: -6.9700 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.2850
Cell Significance Index: -3.5400 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.2862
Cell Significance Index: -5.2900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2865
Cell Significance Index: -9.3800 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.3007
Cell Significance Index: -4.0600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.3036
Cell Significance Index: -7.2800 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.3150
Cell Significance Index: -3.9800 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: -0.3168
Cell Significance Index: -1.9600 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.3210
Cell Significance Index: -6.7000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3231
Cell Significance Index: -10.2900 - Cell Name: peg cell (CL4033014)
Fold Change: -0.3287
Cell Significance Index: -7.6000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3326
Cell Significance Index: -12.2100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3384
Cell Significance Index: -9.7000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3407
Cell Significance Index: -10.0400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3505
Cell Significance Index: -12.2800 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.3509
Cell Significance Index: -3.6300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3511
Cell Significance Index: -4.7900 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.3569
Cell Significance Index: -4.4500 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.3597
Cell Significance Index: -5.3900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.3697
Cell Significance Index: -7.6700 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.3712
Cell Significance Index: -4.7600 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.3781
Cell Significance Index: -7.5900 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3823
Cell Significance Index: -8.2600 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.3835
Cell Significance Index: -4.8400 - Cell Name: ependymal cell (CL0000065)
Fold Change: -0.3946
Cell Significance Index: -4.6500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4245154636
Symbol: RA51D_HUMAN
Name: DNA repair protein RAD51 homolog 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9512535
Title: Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family.
PubMed ID: 9512535
PubMed ID: 9570954
Title: Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene.
PubMed ID: 9570954
PubMed ID: 10092526
Title: Multiple alternative transcripts of the human homologue of the mouse TRAD/R51H3/RAD51D gene, a member of the recA/RAD51 gene family.
PubMed ID: 10092526
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 10871607
Title: The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2.
PubMed ID: 10871607
PubMed ID: 11751635
Title: Identification and purification of two distinct complexes containing the five RAD51 paralogs.
PubMed ID: 11751635
DOI: 10.1101/gad.947001
PubMed ID: 11834724
Title: Homologous pairing and ring and filament structure formation activities of the human Xrcc2*Rad51D complex.
PubMed ID: 11834724
PubMed ID: 11842113
Title: Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells.
PubMed ID: 11842113
PubMed ID: 11744692
Title: RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51.
PubMed ID: 11744692
PubMed ID: 11842112
Title: Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells.
PubMed ID: 11842112
PubMed ID: 12975363
Title: Functional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D).
PubMed ID: 12975363
PubMed ID: 15109494
Title: Telomere maintenance requires the RAD51D recombination/repair protein.
PubMed ID: 15109494
PubMed ID: 14759258
PubMed ID: 16710300
Title: Sws1 is a conserved regulator of homologous recombination in eukaryotic cells.
PubMed ID: 16710300
PubMed ID: 21276791
Title: Homologous recombination proteins are associated with centrosomes and are required for mitotic stability.
PubMed ID: 21276791
PubMed ID: 21965664
Title: hSWS1.SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair.
PubMed ID: 21965664
PubMed ID: 21822267
Title: Germline mutations in RAD51D confer susceptibility to ovarian cancer.
PubMed ID: 21822267
DOI: 10.1038/ng.893
PubMed ID: 23149936
Title: Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway.
PubMed ID: 23149936
DOI: 10.1128/mcb.00465-12
PubMed ID: 21111057
Title: Structural and functional characterization of the N-terminal domain of human Rad51D.
PubMed ID: 21111057
PubMed ID: 27932480
Title: MAGI2 mutations cause congenital nephrotic syndrome.
PubMed ID: 27932480
Sequence Information:
- Length: 328
- Mass: 35049
- Checksum: 6038DA9356DF354A
- Sequence:
MGVLRVGLCP GLTEEMIQLL RSHRIKTVVD LVSADLEEVA QKCGLSYKAL VALRRVLLAQ FSAFPVNGAD LYEELKTSTA ILSTGIGSLD KLLDAGLYTG EVTEIVGGPG SGKTQVCLCM AANVAHGLQQ NVLYVDSNGG LTASRLLQLL QAKTQDEEEQ AEALRRIQVV HAFDIFQMLD VLQELRGTVA QQVTGSSGTV KVVVVDSVTA VVSPLLGGQQ REGLALMMQL ARELKTLARD LGMAVVVTNH ITRDRDSGRL KPALGRSWSF VPSTRILLDT IEGAGASGGR RMACLAKSSR QPTGFQEMVD IGTWGTSEQS ATLQGDQT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.