Details for: RBBP5

Gene ID: 5929

Symbol: RBBP5

Ensembl ID: ENSG00000117222

Description: RB binding protein 5, histone lysine methyltransferase complex subunit

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 147.4812
    Cell Significance Index: -22.9400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 96.0798
    Cell Significance Index: -24.3700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 65.5180
    Cell Significance Index: -26.9900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 55.1340
    Cell Significance Index: -26.0300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 52.6514
    Cell Significance Index: -21.3900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 47.9018
    Cell Significance Index: -24.6400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 22.4354
    Cell Significance Index: -21.4200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 20.1954
    Cell Significance Index: -24.9000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.4350
    Cell Significance Index: -25.2800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.4406
    Cell Significance Index: -25.4200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.1372
    Cell Significance Index: -18.8500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.1579
    Cell Significance Index: -9.1000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1561
    Cell Significance Index: 114.3700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.9656
    Cell Significance Index: 112.5300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9206
    Cell Significance Index: 12.5600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8870
    Cell Significance Index: 177.9400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7552
    Cell Significance Index: 149.8700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7372
    Cell Significance Index: 44.2600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7031
    Cell Significance Index: 76.4800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6056
    Cell Significance Index: 98.4900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3522
    Cell Significance Index: 7.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3432
    Cell Significance Index: 23.7400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3206
    Cell Significance Index: 39.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3145
    Cell Significance Index: 19.8200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3038
    Cell Significance Index: 108.9800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2776
    Cell Significance Index: 50.0500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2676
    Cell Significance Index: 6.6900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2251
    Cell Significance Index: 99.5300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2206
    Cell Significance Index: 6.3600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2147
    Cell Significance Index: 25.3200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2120
    Cell Significance Index: 146.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2112
    Cell Significance Index: 29.0100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1981
    Cell Significance Index: 25.3900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1726
    Cell Significance Index: 32.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1551
    Cell Significance Index: 10.4300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1511
    Cell Significance Index: 82.5000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1210
    Cell Significance Index: 5.6400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1205
    Cell Significance Index: 9.2500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1108
    Cell Significance Index: 5.0200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0878
    Cell Significance Index: 2.3900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0846
    Cell Significance Index: 4.4400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0817
    Cell Significance Index: 9.3300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0803
    Cell Significance Index: 3.7800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0725
    Cell Significance Index: 65.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0713
    Cell Significance Index: 12.1700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0599
    Cell Significance Index: 3.1100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0586
    Cell Significance Index: 2.2200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0427
    Cell Significance Index: 1.5000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0421
    Cell Significance Index: 1.8600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0340
    Cell Significance Index: 0.9500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0259
    Cell Significance Index: 1.8300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0242
    Cell Significance Index: 1.4900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0128
    Cell Significance Index: 0.7200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0076
    Cell Significance Index: 14.3700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0031
    Cell Significance Index: 0.2300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0008
    Cell Significance Index: 0.5100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0019
    Cell Significance Index: -0.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0044
    Cell Significance Index: -8.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0062
    Cell Significance Index: -4.5900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0072
    Cell Significance Index: -4.4900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0087
    Cell Significance Index: -13.3800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0109
    Cell Significance Index: -4.9300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0133
    Cell Significance Index: -18.0500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0152
    Cell Significance Index: -11.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0204
    Cell Significance Index: -11.5000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0216
    Cell Significance Index: -0.3700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0247
    Cell Significance Index: -18.7100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0359
    Cell Significance Index: -4.6400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0360
    Cell Significance Index: -5.2400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0521
    Cell Significance Index: -3.3600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0527
    Cell Significance Index: -5.3800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0553
    Cell Significance Index: -1.9200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0615
    Cell Significance Index: -12.9600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0712
    Cell Significance Index: -20.4900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0836
    Cell Significance Index: -2.1500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0881
    Cell Significance Index: -1.4800
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0895
    Cell Significance Index: -1.3600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0946
    Cell Significance Index: -10.8400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1207
    Cell Significance Index: -2.5700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1316
    Cell Significance Index: -2.7300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1351
    Cell Significance Index: -1.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1422
    Cell Significance Index: -3.7400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1508
    Cell Significance Index: -4.8300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2349
    Cell Significance Index: -24.4600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2601
    Cell Significance Index: -20.6000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2698
    Cell Significance Index: -7.2300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2737
    Cell Significance Index: -5.7300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2758
    Cell Significance Index: -6.0400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3066
    Cell Significance Index: -15.9700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3774
    Cell Significance Index: -10.7700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3799
    Cell Significance Index: -10.8900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4180
    Cell Significance Index: -25.6300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4207
    Cell Significance Index: -8.2100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4293
    Cell Significance Index: -6.4700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4713
    Cell Significance Index: -15.0100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4720
    Cell Significance Index: -11.3200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4910
    Cell Significance Index: -16.0800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5005
    Cell Significance Index: -14.7000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5138
    Cell Significance Index: -13.7500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5347
    Cell Significance Index: -15.7500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** RBBP5 is a protein-coding gene with an Ensembl ID of ENSG00000117222. It is significantly expressed in various cell types, including L6b glutamatergic cortical neurons, L2/3-6 intratelencephalic projecting glutamatergic neurons, corticothalamic-projecting glutamatergic cortical neurons, and cerebral cortex GABAergic interneurons. The gene is involved in the formation of the MLL1 complex, which is a histone methyltransferase complex that plays a critical role in development and epigenetic regulation. **Pathways and Functions** RBBP5 is involved in several key pathways, including: 1. **Activation of anterior hox genes in hindbrain development during early embryogenesis**: RBBP5 is required for the activation of anterior hox genes, which are essential for the development of the hindbrain during embryogenesis. 2. **Activation of hox genes during differentiation**: RBBP5 is involved in the activation of hox genes during differentiation, which is crucial for the development and maintenance of various cell types. 3. **Chromatin modifying enzymes**: RBBP5 is a component of the MLL1 complex, which is a histone methyltransferase complex that modifies chromatin structure and regulates gene expression. 4. **Epigenetic regulation of gene expression**: RBBP5 is involved in the regulation of gene expression through epigenetic mechanisms, such as histone modification and DNA methylation. 5. **Gene expression (transcription)**: RBBP5 is required for the regulation of gene expression through transcriptional regulation. **Functions** The functions of RBBP5 include: 1. **Histone binding**: RBBP5 binds to histones, which is essential for the formation of the MLL1 complex and the regulation of chromatin structure. 2. **Histone methyltransferase activity**: RBBP5 is a histone methyltransferase, which adds methyl groups to histones, leading to changes in chromatin structure and gene expression. 3. **Protein binding**: RBBP5 interacts with various proteins, including transcription factors and chromatin-modifying enzymes, to regulate gene expression and cellular signaling. 4. **Post-translational protein modification**: RBBP5 is involved in the regulation of post-translational protein modification, including phosphorylation and ubiquitination. **Clinical Significance** RBBP5 has significant clinical implications, including: 1. **Developmental disorders**: RBBP5 mutations have been associated with developmental disorders, such as intellectual disability and autism spectrum disorder. 2. **Cancer**: RBBP5 is often overexpressed in various types of cancer, including leukemia and lymphoma, and is associated with poor prognosis. 3. **Neurological disorders**: RBBP5 has been implicated in various neurological disorders, including schizophrenia and bipolar disorder. 4. **Epigenetic disorders**: RBBP5 is involved in the regulation of epigenetic marks, which are essential for the development and maintenance of various cell types. In conclusion, RBBP5 is a critical gene that plays a significant role in various cellular processes, including development, epigenetic regulation, and cellular signaling. Its dysregulation has significant clinical implications, including developmental disorders, cancer, neurological disorders, and epigenetic disorders. Further research is needed to fully understand the function and clinical significance of RBBP5.

Genular Protein ID: 1692998406

Symbol: RBBP5_HUMAN

Name: Retinoblastoma-binding protein 5

UniProtKB Accession Codes:

Q15291 A8K272 Q7Z6D8 Q8NDZ7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 6 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 15 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 27 PDBsum 27 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 7 RefSeq 3 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7558034

Title: Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping.

PubMed ID: 7558034

DOI: 10.1006/geno.1995.1084

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14992727

Title: Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.

PubMed ID: 14992727

DOI: 10.1016/s1097-2765(04)00081-4

PubMed ID: 15199122

Title: Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

PubMed ID: 15199122

DOI: 10.1128/mcb.24.13.5639-5649.2004

PubMed ID: 15960975

Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

PubMed ID: 15960975

DOI: 10.1016/j.cell.2005.04.031

PubMed ID: 16253997

Title: CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex.

PubMed ID: 16253997

DOI: 10.1074/jbc.m508312200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17355966

Title: Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.

PubMed ID: 17355966

DOI: 10.1074/jbc.m609809200

PubMed ID: 17500065

Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

PubMed ID: 17500065

DOI: 10.1074/jbc.m701574200

PubMed ID: 17998332

Title: Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.

PubMed ID: 17998332

DOI: 10.1128/mcb.01356-07

PubMed ID: 18838538

Title: Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS.

PubMed ID: 18838538

DOI: 10.1128/mcb.00976-08

PubMed ID: 19131338

Title: Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation.

PubMed ID: 19131338

DOI: 10.1074/jbc.m805872200

PubMed ID: 19556245

Title: On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

PubMed ID: 19556245

DOI: 10.1074/jbc.m109.014498

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23178126

Title: Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation.

PubMed ID: 23178126

DOI: 10.1016/j.cell.2012.10.043

PubMed ID: 22266653

Title: The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

PubMed ID: 22266653

DOI: 10.1093/nar/gkr1235

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 21220120

Title: Structural and biochemical insights into MLL1 core complex assembly.

PubMed ID: 21220120

DOI: 10.1016/j.str.2010.09.022

Sequence Information:

  • Length: 538
  • Mass: 59153
  • Checksum: 095CCB41613CBED9
  • Sequence:
    • MNLELLESFG QNYPEEADGT LDCISMALTC TFNRWGTLLA VGCNDGRIVI WDFLTRGIAK 
IISAHIHPVC SLCWSRDGHK LVSASTDNIV SQWDVLSGDC DQRFRFPSPI LKVQYHPRDQ 
NKVLVCPMKS APVMLTLSDS KHVVLPVDDD SDLNVVASFD RRGEYIYTGN AKGKILVLKT 
DSQDLVASFR VTTGTSNTTA IKSIEFARKG SCFLINTADR IIRVYDGREI LTCGRDGEPE 
PMQKLQDLVN RTPWKKCCFS GDGEYIVAGS ARQHALYIWE KSIGNLVKIL HGTRGELLLD 
VAWHPVRPII ASISSGVVSI WAQNQVENWS AFAPDFKELD ENVEYEERES EFDIEDEDKS 
EPEQTGADAA EDEEVDVTSV DPIAAFCSSD EELEDSKALL YLPIAPEVED PEENPYGPPP 
DAVQTSLMDE GASSEKKRQS SADGSQPPKK KPKTTNIELQ GVPNDEVHPL LGVKGDGKSK 
KKQAGRPKGS KGKEKDSPFK PKLYKGDRGL PLEGSAKGKV QAELSQPLTA GGAISELL

Genular Protein ID: 2225529535

Symbol: B4DLF8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DLF8

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 410
  • Mass: 44832
  • Checksum: 7198BB77E1F9B683
  • Sequence:
    • MKSAPVMLTL SDSKHVVLPV DDDSDLNVVA SFDRRGEYIY TGNAKGKILV LKTDSQDLVA 
SFRVTTGTSN TTAIKSIEFA RKGSCFLINT ADRIIRVYDG REILTCGRDG EPEPMQKLQD 
LVNRTPWKKC CFSGDGEYIV AGSARQHALY IWEKSIGNLV KILHGTRGEL LLDVAWHPVR 
PIIASISSGV ISIWAQNQVE NWSAFAPDFK ELDENVEYEE RESEFDIEDE DKSEPEQTGA 
DAAEDEEVDV TSVDPIAAFC SSDEELEDSK ALLYLPIAPE VEDPEENPYG PPPDAVQTSL 
MDEGASSEKK RQSSADGSQP PKKKPKTTNI ELQGVPNDEV HPLLGVKGDG KSKKKQAGRP 
KGSKGKEKDS PFKPKLYKGD RGLPLEGSAK GKVQAELSQP LTGGAISELL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.