Details for: RBL1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 84.8306
Cell Significance Index: -13.2000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 64.6577
Cell Significance Index: -16.4000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 37.6670
Cell Significance Index: -15.3000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 16.1195
Cell Significance Index: -15.3900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.6663
Cell Significance Index: -16.8500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 6.8462
Cell Significance Index: -18.3400 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.8804
Cell Significance Index: -14.9900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 4.7428
Cell Significance Index: -10.3800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.3765
Cell Significance Index: -17.2700 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 3.1149
Cell Significance Index: 51.3300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.0964
Cell Significance Index: 117.6400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.3589
Cell Significance Index: 269.6700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.3477
Cell Significance Index: 29.5100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.1966
Cell Significance Index: 33.4400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5892
Cell Significance Index: 211.3300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.5600
Cell Significance Index: 34.4200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.5131
Cell Significance Index: 12.3100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5007
Cell Significance Index: 81.4300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4828
Cell Significance Index: 47.7600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4623
Cell Significance Index: 50.2900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.4561
Cell Significance Index: 27.3800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.3131
Cell Significance Index: 45.5100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2725
Cell Significance Index: 32.1400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2492
Cell Significance Index: 6.2300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2416
Cell Significance Index: 4.1400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2354
Cell Significance Index: 162.8200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2288
Cell Significance Index: 14.4200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.2170
Cell Significance Index: 16.6500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1983
Cell Significance Index: 179.0400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1265
Cell Significance Index: 2.7400 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1225
Cell Significance Index: 2.3900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1135
Cell Significance Index: 3.2700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1095
Cell Significance Index: 19.7400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.1032
Cell Significance Index: 2.7600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0731
Cell Significance Index: 1.8800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0710
Cell Significance Index: 31.3800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0667
Cell Significance Index: 12.7000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0549
Cell Significance Index: 3.8000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0525
Cell Significance Index: 80.8400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.0515
Cell Significance Index: 2.2800 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.0499
Cell Significance Index: 0.7100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0407
Cell Significance Index: 76.6700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0329
Cell Significance Index: 17.9700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0325
Cell Significance Index: 44.2000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0319
Cell Significance Index: 58.8200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0285
Cell Significance Index: 3.5100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0199
Cell Significance Index: 12.6300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0191
Cell Significance Index: 2.2300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0129
Cell Significance Index: 5.8600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0124
Cell Significance Index: 0.4400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0066
Cell Significance Index: 1.3200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0042
Cell Significance Index: 0.1600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0033
Cell Significance Index: 0.1500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0026
Cell Significance Index: 0.3600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0041
Cell Significance Index: -0.1100 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.0047
Cell Significance Index: -0.0700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0155
Cell Significance Index: -0.8000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0168
Cell Significance Index: -0.2000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0178
Cell Significance Index: -1.1500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0182
Cell Significance Index: -13.3800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0198
Cell Significance Index: -14.6800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0231
Cell Significance Index: -17.5200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0289
Cell Significance Index: -0.6000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0301
Cell Significance Index: -18.8000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0302
Cell Significance Index: -17.0400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0376
Cell Significance Index: -0.8000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0406
Cell Significance Index: -6.9300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0605
Cell Significance Index: -17.4100 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0711
Cell Significance Index: -9.1200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0859
Cell Significance Index: -8.7800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0862
Cell Significance Index: -18.1700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0962
Cell Significance Index: -11.0200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0968
Cell Significance Index: -6.5100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1068
Cell Significance Index: -7.5500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1323
Cell Significance Index: -13.7800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1341
Cell Significance Index: -17.3300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1398
Cell Significance Index: -8.5700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1600
Cell Significance Index: -8.3100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1767
Cell Significance Index: -2.5300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1835
Cell Significance Index: -8.5600 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1858
Cell Significance Index: -2.8000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1917
Cell Significance Index: -9.0100 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.2048
Cell Significance Index: -2.5400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2095
Cell Significance Index: -16.5900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2296
Cell Significance Index: -17.1100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2310
Cell Significance Index: -12.1300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2324
Cell Significance Index: -7.4500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2384
Cell Significance Index: -5.0600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.2508
Cell Significance Index: -6.1200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2566
Cell Significance Index: -7.5400 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2665
Cell Significance Index: -5.2700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.2711
Cell Significance Index: -5.8000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2999
Cell Significance Index: -9.5500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3053
Cell Significance Index: -5.1100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3079
Cell Significance Index: -10.0800 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.3128
Cell Significance Index: -3.9000 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.3301
Cell Significance Index: -4.7400 - Cell Name: glioblast (CL0000030)
Fold Change: -0.3312
Cell Significance Index: -2.0800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3335
Cell Significance Index: -11.5900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.3407
Cell Significance Index: -5.0300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4182886191
Symbol: RBL1_HUMAN
Name: Retinoblastoma-like protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8319904
Title: Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
PubMed ID: 8319904
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1833063
Title: Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein.
PubMed ID: 1833063
PubMed ID: 7791762
Title: Differential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins.
PubMed ID: 7791762
PubMed ID: 11884610
Title: Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4.
PubMed ID: 11884610
PubMed ID: 2546678
Title: The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus.
PubMed ID: 2546678
PubMed ID: 7935440
Title: Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein.
PubMed ID: 7935440
PubMed ID: 12450794
Title: Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb.
PubMed ID: 12450794
PubMed ID: 12006580
Title: Distinct phosphorylation events regulate p130- and p107-mediated repression of E2F-4.
PubMed ID: 12006580
PubMed ID: 16360038
Title: Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
PubMed ID: 16360038
PubMed ID: 17671431
Title: LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes.
PubMed ID: 17671431
DOI: 10.4161/cc.6.15.4512
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20485545
Title: JC virus small T antigen binds phosphatase PP2A and Rb family proteins and is required for efficient viral DNA replication activity.
PubMed ID: 20485545
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 1068
- Mass: 120847
- Checksum: 2BC4876EA04BDB31
- Sequence:
MFEDKPHAEG AAVVAAAGEA LQALCQELNL DEGSAAEALD DFTAIRGNYS LEGEVTHWLA CSLYVACRKS IIPTVGKGIM EGNCVSLTRI LRSAKLSLIQ FFSKMKKWMD MSNLPQEFRE RIERLERNFE VSTVIFKKYE PIFLDIFQNP YEEPPKLPRS RKQRRIPCSV KDLFNFCWTL FVYTKGNFRM IGDDLVNSYH LLLCCLDLIF ANAIMCPNRQ DLLNPSFKGL PSDFHTADFT ASEEPPCIIA VLCELHDGLL VEAKGIKEHY FKPYISKLFD RKILKGECLL DLSSFTDNSK AVNKEYEEYV LTVGDFDERI FLGADAEEEI GTPRKFTRDT PLGKLTAQAN VEYNLQQHFE KKRSFAPSTP LTGRRYLREK EAVITPVASA TQSVSRLQSI VAGLKNAPSD QLINIFESCV RNPVENIMKI LKGIGETFCQ HYTQSTDEQP GSHIDFAVNR LKLAEILYYK ILETVMVQET RRLHGMDMSV LLEQDIFHRS LMACCLEIVL FAYSSPRTFP WIIEVLNLQP FYFYKVIEVV IRSEEGLSRD MVKHLNSIEE QILESLAWSH DSALWEALQV SANKVPTCEE VIFPNNFETG NGGNVQGHLP LMPMSPLMHP RVKEVRTDSG SLRRDMQPLS PISVHERYSS PTAGSAKRRL FGEDPPKEML MDKIITEGTK LKIAPSSSIT AENVSILPGQ TLLTMATAPV TGTTGHKVTI PLHGVANDAG EITLIPLSMN TNQESKVKSP VSLTAHSLIG ASPKQTNLTK AQEVHSTGIN RPKRTGSLAL FYRKVYHLAS VRLRDLCLKL DVSNELRRKI WTCFEFTLVH CPDLMKDRHL DQLLLCAFYI MAKVTKEERT FQEIMKSYRN QPQANSHVYR SVLLKSIPRE VVAYNKNIND DFEMIDCDLE DATKTPDCSS GPVKEERGDL IKFYNTIYVG RVKSFALKYD LANQDHMMDA PPLSPFPHIK QQPGSPRRIS QQHSIYISPH KNGSGLTPRS ALLYKFNGSP SKSLKDINNM IRQGEQRTKK RVIAIDSDAE SPAKRVCQEN DDVLLKRLQD VVSERANH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.