Details for: RPS2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: embryonic stem cell (CL0002322)
Fold Change: 771.8943
Cell Significance Index: -317.9800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 650.6148
Cell Significance Index: -307.1700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 617.7277
Cell Significance Index: -317.7500 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 460.3127
Cell Significance Index: -308.8800 - Cell Name: theca cell (CL0000503)
Fold Change: 29.7156
Cell Significance Index: 174.5800 - Cell Name: pro-T cell (CL0000827)
Fold Change: 24.2041
Cell Significance Index: 618.3400 - Cell Name: abnormal cell (CL0001061)
Fold Change: 18.0122
Cell Significance Index: 1839.9500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 17.7800
Cell Significance Index: -47.6300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 15.4690
Cell Significance Index: 537.5400 - Cell Name: granulosa cell (CL0000501)
Fold Change: 15.1261
Cell Significance Index: 397.7400 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 14.2624
Cell Significance Index: 252.0400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 14.1435
Cell Significance Index: 664.7300 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 13.5168
Cell Significance Index: 116.1500 - Cell Name: lactocyte (CL0002325)
Fold Change: 12.0454
Cell Significance Index: 1556.1800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 12.0199
Cell Significance Index: 251.6000 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 11.6848
Cell Significance Index: 132.7500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 11.3230
Cell Significance Index: 145.0100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 10.5921
Cell Significance Index: 749.1200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 10.1483
Cell Significance Index: 1247.8300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 10.0957
Cell Significance Index: 1819.9300 - Cell Name: peg cell (CL4033014)
Fold Change: 9.6925
Cell Significance Index: 223.9300 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 9.6612
Cell Significance Index: 105.0300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 9.5906
Cell Significance Index: 714.7800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 9.5231
Cell Significance Index: 1307.7900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 8.8575
Cell Significance Index: 3916.1100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 8.7589
Cell Significance Index: 4783.4300 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 7.9580
Cell Significance Index: 48.9800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 7.9551
Cell Significance Index: 513.2300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 7.9091
Cell Significance Index: 226.7200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 7.0385
Cell Significance Index: 830.0600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 6.2361
Cell Significance Index: 4720.2500 - Cell Name: odontoblast (CL0000060)
Fold Change: 6.1695
Cell Significance Index: 790.9000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 5.9286
Cell Significance Index: 54.6000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 5.7078
Cell Significance Index: 974.6400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 5.6754
Cell Significance Index: 166.6800 - Cell Name: kidney cell (CL1000497)
Fold Change: 5.4119
Cell Significance Index: 43.2100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.8404
Cell Significance Index: 225.6800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.5010
Cell Significance Index: 83.1900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 4.1761
Cell Significance Index: 219.2600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 4.0435
Cell Significance Index: 110.0600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 3.9843
Cell Significance Index: 3597.5500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 3.9324
Cell Significance Index: 105.0000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.5196
Cell Significance Index: 500.0200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.4982
Cell Significance Index: 171.6400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.1277
Cell Significance Index: 51.1200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.0531
Cell Significance Index: 200.4100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.0093
Cell Significance Index: 52.4300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.9551
Cell Significance Index: 700.2500 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 0.7937
Cell Significance Index: 5.7000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.4657
Cell Significance Index: 134.0000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3602
Cell Significance Index: 35.6300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0498
Cell Significance Index: 1.4400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 0.0340
Cell Significance Index: 2.6900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0423
Cell Significance Index: -4.8300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0656
Cell Significance Index: -2.3100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0981
Cell Significance Index: -184.6700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1265
Cell Significance Index: -7.1000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1286
Cell Significance Index: -95.2600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1766
Cell Significance Index: -325.6500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.2075
Cell Significance Index: -74.4100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.2190
Cell Significance Index: -337.0900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2271
Cell Significance Index: -11.4800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.2772
Cell Significance Index: -376.8700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.2787
Cell Significance Index: -157.2000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.2888
Cell Significance Index: -180.3600 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.3626
Cell Significance Index: -14.8600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.3830
Cell Significance Index: -76.8200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.4124
Cell Significance Index: -261.9000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.6209
Cell Significance Index: -281.7900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.6639
Cell Significance Index: -139.8300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.9783
Cell Significance Index: -159.1200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.2119
Cell Significance Index: -38.8200 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.4021
Cell Significance Index: -24.1700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.4608
Cell Significance Index: -101.0300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.9109
Cell Significance Index: -277.7700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -2.1397
Cell Significance Index: -35.8100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -2.6419
Cell Significance Index: -66.0400 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -2.7227
Cell Significance Index: -16.4500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -2.9365
Cell Significance Index: -305.7600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -3.2307
Cell Significance Index: -203.6200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -4.1929
Cell Significance Index: -321.7600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -4.3031
Cell Significance Index: -263.8200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -4.4624
Cell Significance Index: -267.9000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -6.0290
Cell Significance Index: -177.5800 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -6.0971
Cell Significance Index: -91.3600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -6.1081
Cell Significance Index: -132.3300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -6.2021
Cell Significance Index: -84.6200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -6.9748
Cell Significance Index: -308.5100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -7.1952
Cell Significance Index: -264.1300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -7.9044
Cell Significance Index: -211.8000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -7.9560
Cell Significance Index: -94.8400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -7.9655
Cell Significance Index: -204.7500 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -8.0764
Cell Significance Index: -50.1800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -8.1765
Cell Significance Index: -309.6300 - Cell Name: perivascular cell (CL4033054)
Fold Change: -8.2929
Cell Significance Index: -38.2900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -8.3986
Cell Significance Index: -274.9700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -8.4777
Cell Significance Index: -296.9900 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -8.7661
Cell Significance Index: -47.8000 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -8.7668
Cell Significance Index: -181.8600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -9.0006
Cell Significance Index: -286.6600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 705244253
Symbol: RS2_HUMAN
Name: 40S ribosomal protein S2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2308862
Title: Human cDNA sequence homologous to the mouse LLRep3 gene family.
PubMed ID: 2308862
DOI: 10.1093/nar/18.3.681
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8706699
Title: Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.
PubMed ID: 8706699
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 15473865
Title: Ribosomal protein S2 is a substrate for mammalian PRMT3 (protein arginine methyltransferase 3).
PubMed ID: 15473865
DOI: 10.1042/bj20041466
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21584310
Title: Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2.
PubMed ID: 21584310
DOI: 10.1039/c1mb05089c
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24524803
Title: A new system for naming ribosomal proteins.
PubMed ID: 24524803
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28132843
Title: ZNF598 and RACK1 regulate mammalian ribosome-associated quality control function by mediating regulatory 40S ribosomal ubiquitylation.
PubMed ID: 28132843
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 30530495
Title: The 40S ribosomal protein uS5 (RPS2) assembles into an extraribosomal complex with human ZNF277 that competes with the PRMT3-uS5 interaction.
PubMed ID: 30530495
PubMed ID: 32011234
Title: Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized.
PubMed ID: 32011234
DOI: 10.7554/elife.54023
PubMed ID: 31981475
Title: The G3BP1-family-USP10 deubiquitinase complex rescues ubiquitinated 40S subunits of ribosomes stalled in translation from lysosomal degradation.
PubMed ID: 31981475
PubMed ID: 34348161
Title: The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation.
PubMed ID: 34348161
PubMed ID: 34469731
Title: iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation.
PubMed ID: 34469731
PubMed ID: 23636399
Title: Structures of the human and Drosophila 80S ribosome.
PubMed ID: 23636399
DOI: 10.1038/nature12104
Sequence Information:
- Length: 293
- Mass: 31324
- Checksum: 66C0DB7ED393B036
- Sequence:
MADDAGAAGG PGGPGGPGMG NRGGFRGGFG SGIRGRGRGR GRGRGRGRGA RGGKAEDKEW MPVTKLGRLV KDMKIKSLEE IYLFSLPIKE SEIIDFFLGA SLKDEVLKIM PVQKQTRAGQ RTRFKAFVAI GDYNGHVGLG VKCSKEVATA IRGAIILAKL SIVPVRRGYW GNKIGKPHTV PCKVTGRCGS VLVRLIPAPR GTGIVSAPVP KKLLMMAGID DCYTSARGCT ATLGNFAKAT FDAISKTYSY LTPDLWKETV FTKSPYQEFT DHLVKTHTRV SVQRTQAPAV ATT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.