Details for: RYK
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 333.1507
Cell Significance Index: -51.8200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 201.6611
Cell Significance Index: -51.1500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 111.4541
Cell Significance Index: -52.6200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 105.9181
Cell Significance Index: -43.0300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 96.1342
Cell Significance Index: -49.4500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 45.0697
Cell Significance Index: -43.0300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 42.6293
Cell Significance Index: -52.5600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 18.7057
Cell Significance Index: -50.1100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 14.2017
Cell Significance Index: -43.6200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 13.3703
Cell Significance Index: -52.7600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.8283
Cell Significance Index: -21.5100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.5719
Cell Significance Index: 35.0900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 2.0648
Cell Significance Index: 240.6300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.0545
Cell Significance Index: 115.2900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.0037
Cell Significance Index: 401.9400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.6496
Cell Significance Index: 591.7000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.5821
Cell Significance Index: 313.9700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.3783
Cell Significance Index: 38.5200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.9675
Cell Significance Index: 174.4200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.9526
Cell Significance Index: 73.1000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.8391
Cell Significance Index: 103.1700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.7826
Cell Significance Index: 52.6200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.7807
Cell Significance Index: 539.9900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.7305
Cell Significance Index: 44.9000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.6696
Cell Significance Index: 91.9600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6142
Cell Significance Index: 554.5900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.5788
Cell Significance Index: 25.6000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5782
Cell Significance Index: 315.7800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5656
Cell Significance Index: 250.0700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.5493
Cell Significance Index: 13.7300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.5222
Cell Significance Index: 19.7700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.4910
Cell Significance Index: 12.6200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.4556
Cell Significance Index: 21.2400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4441
Cell Significance Index: 23.0700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4365
Cell Significance Index: 43.1800 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.3631
Cell Significance Index: 7.0900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.3228
Cell Significance Index: 8.7900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2992
Cell Significance Index: 13.5600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2836
Cell Significance Index: 13.3300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2605
Cell Significance Index: 401.0000 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2545
Cell Significance Index: 32.6200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2543
Cell Significance Index: 17.9900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2406
Cell Significance Index: 12.5300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2267
Cell Significance Index: 43.1400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1914
Cell Significance Index: 353.0200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1732
Cell Significance Index: 326.0700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1614
Cell Significance Index: 3.8700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1333
Cell Significance Index: 84.6800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0670
Cell Significance Index: 91.1500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0633
Cell Significance Index: 1.8300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0535
Cell Significance Index: 24.3000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.0529
Cell Significance Index: 1.5100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0045
Cell Significance Index: -0.1200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0236
Cell Significance Index: -3.4300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0342
Cell Significance Index: -25.0700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0342
Cell Significance Index: -5.8400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0505
Cell Significance Index: -38.2400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0584
Cell Significance Index: -43.2300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0904
Cell Significance Index: -56.4300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0965
Cell Significance Index: -2.0900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0969
Cell Significance Index: -54.6700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1102
Cell Significance Index: -3.1600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1175
Cell Significance Index: -3.0900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1357
Cell Significance Index: -4.7700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1488
Cell Significance Index: -19.2200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1591
Cell Significance Index: -45.7800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2696
Cell Significance Index: -27.5400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2865
Cell Significance Index: -4.9100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2898
Cell Significance Index: -61.0400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.3178
Cell Significance Index: -8.5100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3254
Cell Significance Index: -20.5100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3412
Cell Significance Index: -25.4300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.3432
Cell Significance Index: -7.1200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3441
Cell Significance Index: -7.5400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3595
Cell Significance Index: -41.1800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3748
Cell Significance Index: -39.0300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3784
Cell Significance Index: -44.6200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3900
Cell Significance Index: -12.4900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.5381
Cell Significance Index: -7.9500 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.5465
Cell Significance Index: -7.8600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5734
Cell Significance Index: -45.4100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6026
Cell Significance Index: -10.0900 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.6727
Cell Significance Index: -9.6600 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.6844
Cell Significance Index: -14.6300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.6869
Cell Significance Index: -4.1500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6904
Cell Significance Index: -42.3300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.7527
Cell Significance Index: -48.5600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7981
Cell Significance Index: -27.7400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.8443
Cell Significance Index: -7.7800 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.8644
Cell Significance Index: -14.5600 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.9214
Cell Significance Index: -13.6000 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.9222
Cell Significance Index: -46.6100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.9452
Cell Significance Index: -49.6300 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.9519
Cell Significance Index: -19.1100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.9611
Cell Significance Index: -30.6100 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.9892
Cell Significance Index: -21.0000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.0165
Cell Significance Index: -33.2800 - Cell Name: peg cell (CL4033014)
Fold Change: -1.0295
Cell Significance Index: -23.7900 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -1.1806
Cell Significance Index: -10.4800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.1844
Cell Significance Index: -23.4200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2176804596
Symbol: RYK_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8386829
Title: Molecular cloning and chromosomal localisation of the human homologue of a receptor related to tyrosine kinases (RYK).
PubMed ID: 8386829
PubMed ID: 8390040
Title: The human ryk cDNA sequence predicts a protein containing two putative transmembrane segments and a tyrosine kinase catalytic domain.
PubMed ID: 8390040
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 8726462
Title: H-RYK, an unusual receptor kinase: isolation and analysis of expression in ovarian cancer.
PubMed ID: 8726462
DOI: 10.1007/bf03401616
PubMed ID: 10454588
Title: Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family.
PubMed ID: 10454588
PubMed ID: 15454084
Title: Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth.
PubMed ID: 15454084
PubMed ID: 16116452
Title: Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract.
PubMed ID: 16116452
DOI: 10.1038/nn1520
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 607
- Mass: 67815
- Checksum: 3AFAE21A2680F400
- Sequence:
MRGAARLGRP GRSCLPGARG LRAPPPPPLL LLLALLPLLP APGAAAAPAP RPPELQSASA GPSVSLYLSE DEVRRLIGLD AELYYVRNDL ISHYALSFSL LVPSETNFLH FTWHAKSKVE YKLGFQVDNV LAMDMPQVNI SVQGEVPRTL SVFRVELSCT GKVDSEVMIL MQLNLTVNSS KNFTVLNFKR RKMCYKKLEE VKTSALDKNT SRTIYDPVHA APTTSTRVFY ISVGVCCAVI FLVAIILAVL HLHSMKRIEL DDSISASSSS QGLSQPSTQT TQYLRADTPN NATPITSYPT LRIEKNDLRS VTLLEAKGKV KDIAISRERI TLKDVLQEGT FGRIFHGILI DEKDPNKEKQ AFVKTVKDQA SEIQVTMMLT ESCKLRGLHH RNLLPITHVC IEEGEKPMVI LPYMNWGNLK LFLRQCKLVE ANNPQAISQQ DLVHMAIQIA CGMSYLARRE VIHKDLAARN CVIDDTLQVK ITDNALSRDL FPMDYHCLGD NENRPVRWMA LESLVNNEFS SASDVWAFGV TLWELMTLGQ TPYVDIDPFE MAAYLKDGYR IAQPINCPDE LFAVMACCWA LDPEERPKFQ QLVQCLTEFH AALGAYV
Genular Protein ID: 2881397041
Symbol: Q8WTZ8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 395
- Mass: 44354
- Checksum: 6A8E7F6B95C6623B
- Sequence:
DPVHAAPTTS TRVFYISVGV CCAVIFLVAI ILAVLHLHSM KRIELDDSIS ASSSSQGLSQ PSTQTTQYLR ADTPNNATPI TSSLGYPTLR IEKNDLRSVT LLEAKGKVKD IAISRERITL KDVLQEGTFG RIFHGILIDE KDPNKEKQAF VKTVKDQASE IQVTMMLTES CKLRGLHHRN LLPITHVCIE EGEKPMVILP YMNWGNLKLF LRQCKLVEAN NPQAISQQDL VHMAIQIACG MSYLARREVI HKDLAARNCV IDDTLQVKIT DNALSRDLFP MDYHCLGDNE NRPVRWMALE SLVNNEFSSA SDVWAFGVTL WELMTLGQTP YVDIDPFEMA AYLKDGYRIA QPINCPDELF AVMACCWALD PEERPKFQQL VQCLTEFHAA LGAYV
Genular Protein ID: 578336624
Symbol: Q59FQ5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 232
- Mass: 26555
- Checksum: CDB46823CD9A02EC
- Sequence:
HFGFLCLSPN FLLFYRNLLP ITHVCIEEGE KPMVILPYMN WGNLKLFLRQ CKLVEANNPQ AISQQDLVHM AIQIACGMSY LARREVIHKD LAARNCVIDD TLQVKITDNA LSRDLFPMDY HCLGDNENRP VRWMALESLV NNEFSSASDV WAFGVTLWEL MTLGQTPYVD IDPFEMAAYL KDGYRIAQPI NCPDELFAVM ACCWALDPEE RPKFQQLVQC LTEFHAALGA YV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.