Details for: SCP2

Gene ID: 6342

Symbol: SCP2

Ensembl ID: ENSG00000116171

Description: sterol carrier protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 502.8762
    Cell Significance Index: -78.2200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 277.9493
    Cell Significance Index: -70.5000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 215.4643
    Cell Significance Index: -88.7600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 188.3197
    Cell Significance Index: -88.9100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 186.9260
    Cell Significance Index: -75.9400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 165.0320
    Cell Significance Index: -84.8900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 132.4845
    Cell Significance Index: -88.9000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 80.2834
    Cell Significance Index: -76.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 68.9441
    Cell Significance Index: -85.0100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 21.9485
    Cell Significance Index: -86.6100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 19.9301
    Cell Significance Index: -53.3900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 18.8087
    Cell Significance Index: -57.7700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 13.0586
    Cell Significance Index: -28.5800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 5.5013
    Cell Significance Index: 92.6700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.7952
    Cell Significance Index: 25.7400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.5093
    Cell Significance Index: 452.3600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.3583
    Cell Significance Index: 289.9800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.8369
    Cell Significance Index: 1003.2000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.7069
    Cell Significance Index: 88.9100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.7032
    Cell Significance Index: 126.9400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5382
    Cell Significance Index: 305.2700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.5228
    Cell Significance Index: 209.1200
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.4630
    Cell Significance Index: 33.8000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4350
    Cell Significance Index: 287.8500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.3023
    Cell Significance Index: 60.7200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.2894
    Cell Significance Index: 570.0900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1849
    Cell Significance Index: 117.2100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.0925
    Cell Significance Index: 56.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.0804
    Cell Significance Index: 76.4100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 1.0208
    Cell Significance Index: 637.4300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.0114
    Cell Significance Index: 699.5100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9960
    Cell Significance Index: 162.0000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8129
    Cell Significance Index: 291.5900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7543
    Cell Significance Index: 96.7000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.7124
    Cell Significance Index: 84.0100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.7086
    Cell Significance Index: 20.8100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.7030
    Cell Significance Index: 90.8200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6621
    Cell Significance Index: 31.1200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6210
    Cell Significance Index: 40.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.5070
    Cell Significance Index: 86.5800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4798
    Cell Significance Index: 36.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4632
    Cell Significance Index: 88.1400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3945
    Cell Significance Index: 356.2200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3848
    Cell Significance Index: 7.5100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2675
    Cell Significance Index: 7.2800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.2249
    Cell Significance Index: 3.3200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2221
    Cell Significance Index: 5.8400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2040
    Cell Significance Index: 384.1100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1711
    Cell Significance Index: 129.5500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0902
    Cell Significance Index: 66.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0877
    Cell Significance Index: 135.0200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0671
    Cell Significance Index: 123.7800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0339
    Cell Significance Index: 21.5500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0082
    Cell Significance Index: -6.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0151
    Cell Significance Index: -20.5200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0292
    Cell Significance Index: -0.7800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0651
    Cell Significance Index: -29.5300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0661
    Cell Significance Index: -6.7500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0804
    Cell Significance Index: -1.2100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1073
    Cell Significance Index: -3.0000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1093
    Cell Significance Index: -61.6400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1852
    Cell Significance Index: -12.8100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1966
    Cell Significance Index: -41.4000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2471
    Cell Significance Index: -4.1400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2559
    Cell Significance Index: -73.6300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2690
    Cell Significance Index: -30.8200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2832
    Cell Significance Index: -41.1700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3163
    Cell Significance Index: -21.2700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3207
    Cell Significance Index: -19.7100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3504
    Cell Significance Index: -15.5000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3505
    Cell Significance Index: -12.1800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3605
    Cell Significance Index: -9.2100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.3770
    Cell Significance Index: -17.0900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3834
    Cell Significance Index: -20.1300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3910
    Cell Significance Index: -45.5700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4386
    Cell Significance Index: -34.7400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.4703
    Cell Significance Index: -8.3100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5046
    Cell Significance Index: -19.1100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5143
    Cell Significance Index: -58.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.6098
    Cell Significance Index: -66.3300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6516
    Cell Significance Index: -8.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6566
    Cell Significance Index: -41.3800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7333
    Cell Significance Index: -76.3500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.8109
    Cell Significance Index: -17.2700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.8654
    Cell Significance Index: -14.8300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.8786
    Cell Significance Index: -28.1400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.8953
    Cell Significance Index: -18.7400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.8962
    Cell Significance Index: -45.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.9978
    Cell Significance Index: -55.9900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -1.1047
    Cell Significance Index: -12.5500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.2076
    Cell Significance Index: -31.0400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.2676
    Cell Significance Index: -18.7200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.2786
    Cell Significance Index: -27.7000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.3389
    Cell Significance Index: -35.8200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.4309
    Cell Significance Index: -87.7300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.4340
    Cell Significance Index: -26.5100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.4753
    Cell Significance Index: -39.5300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -1.5438
    Cell Significance Index: -10.4600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.5545
    Cell Significance Index: -18.5300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.6308
    Cell Significance Index: -46.7500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Sterol binding**: SCP2 binds to sterols, including cholesterol, bile acids, and other sterols, facilitating their transport and metabolism within cells. 2. **Cytosolic localization**: SCP2 is primarily localized in the cytosol, where it interacts with sterols and other lipids. 3. **Tissue-specific expression**: SCP2 is expressed in various tissues, including the liver, kidney, intestine, and stomach, indicating its widespread role in sterol metabolism. 4. **Multiple functions**: SCP2 is involved in multiple processes, including sterol transport, metabolism, and signaling, highlighting its complexity and versatility. **Pathways and Functions:** 1. **Acetyl-CoA c-acyltransferase activity**: SCP2 is involved in the transfer of acetyl groups from acetyl-CoA to fatty acids, facilitating the metabolism of fatty acids. 2. **Alpha-linolenic acid (ALA) metabolism**: SCP2 plays a role in the metabolism of ALA, a polyunsaturated fatty acid essential for various cellular processes. 3. **Bile acid and bile salt metabolism**: SCP2 is involved in the synthesis and transport of bile acids and bile salts, which are essential for fat digestion and absorption. 4. **Cholesterol binding**: SCP2 binds to cholesterol, facilitating its transport and metabolism within cells. 5. **Intracellular cholesterol transport**: SCP2 is involved in the transport of cholesterol within cells, influencing its availability for various cellular processes. **Clinical Significance:** 1. **Bile acid disorders**: SCP2's involvement in bile acid metabolism makes it a potential target for the treatment of bile acid disorders, such as primary biliary cholangitis. 2. **Cholesterol metabolism**: SCP2's role in cholesterol metabolism highlights its potential as a therapeutic target for the treatment of hypercholesterolemia. 3. **Fatty acid metabolism**: SCP2's involvement in fatty acid metabolism makes it a potential target for the treatment of fatty acid-related disorders, such as obesity and metabolic syndrome. 4. **Neurological disorders**: SCP2's role in sterol metabolism and signaling pathways makes it a potential target for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, SCP2 is a multifunctional protein that plays a critical role in sterol metabolism, influencing various cellular processes, including bile acid and cholesterol synthesis, fatty acid metabolism, and signaling pathways. Its widespread expression and involvement in multiple processes make it a promising target for the treatment of various diseases, including bile acid disorders, hypercholesterolemia, and fatty acid-related disorders.

Genular Protein ID: 1578216651

Symbol: SCP2_HUMAN

Name: Sterol carrier protein 2

UniProtKB Accession Codes:

P22307 A6NM69 B4DGJ9 B4DHP6 C9JC79 D3DQ37 E1B6W5 F2Z3J1 Q15432 Q16622 Q5VVZ1 Q6NXF4 Q99430

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 8 CDD 1 CTD 1 ChEBI 54 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 4 ELM 1 EMBL 31 Ensembl 9 EvolutionaryTrace 1 ExpressionAtlas 1 GO 36 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 8 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 5 RefSeq 8 Rhea 28 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TopDownProteomics 3 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7698762

Title: The structure of the human sterol carrier protein X/sterol carrier protein 2 gene (SCP2).

PubMed ID: 7698762

DOI: 10.1006/geno.1994.1630

PubMed ID: 1718316

Title: cDNAs encoding members of a family of proteins related to human sterol carrier protein 2 and assignment of the gene to human chromosome 1 p21-pter.

PubMed ID: 1718316

DOI: 10.1089/dna.1991.10.559

PubMed ID: 1703300

Title: Cloning and expression of a cDNA encoding human sterol carrier protein 2.

PubMed ID: 1703300

DOI: 10.1073/pnas.88.2.463

PubMed ID: 1483685

Title: Localization of human sterol carrier protein 2 gene and cDNA expression in COS-7 cell.

PubMed ID: 1483685

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8300590

Title: Structure-activity studies of human sterol carrier protein 2.

PubMed ID: 8300590

DOI: 10.1016/s0021-9258(17)41988-0

PubMed ID: 7642518

Title: Sterol carrier protein-2 is involved in cholesterol transfer from the endoplasmic reticulum to the plasma membrane in human fibroblasts.

PubMed ID: 7642518

DOI: 10.1074/jbc.270.32.18723

PubMed ID: 10706581

Title: Peroxisomal fatty acid oxidation disorders and 58 kDa sterol carrier protein X (SCPx). Activity measurements in liver and fibroblasts using a newly developed method.

PubMed ID: 10706581

PubMed ID: 14563822

Title: Regulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3a.

PubMed ID: 14563822

DOI: 10.1194/jlr.m300111-jlr200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 8243660

Title: NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2.

PubMed ID: 8243660

DOI: 10.1016/0014-5793(93)80431-s

PubMed ID: 17157249

Title: Recognition of a functional peroxisome type 1 target by the dynamic import receptor Pex5p.

PubMed ID: 17157249

DOI: 10.1016/j.molcel.2006.10.024

PubMed ID: 16685654

Title: Mutations in the gene encoding peroxisomal sterol carrier protein X (SCPx) cause leukencephalopathy with dystonia and motor neuropathy.

PubMed ID: 16685654

DOI: 10.1086/503921

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 547
  • Mass: 58994
  • Checksum: 29F7551465C7143A
  • Sequence:
    • MSSSPWEPAT LRRVFVVGVG MTKFVKPGAE NSRDYPDLAE EAGKKALADA QIPYSAVDQA 
CVGYVFGDST CGQRAIYHSL GMTGIPIINV NNNCATGSTA LFMARQLIQG GVAECVLALG 
FEKMSKGSLG IKFSDRTIPT DKHVDLLINK YGLSAHPVAP QMFGYAGKEH MEKYGTKIEH 
FAKIGWKNHK HSVNNPYSQF QDEYSLDEVM ASKEVFDFLT ILQCCPTSDG AAAAILASEA 
FVQKYGLQSK AVEILAQEMM TDLPSSFEEK SIIKMVGFDM SKEAARKCYE KSGLTPNDID 
VIELHDCFST NELLTYEALG LCPEGQGATL VDRGDNTYGG KWVINPSGGL ISKGHPLGAT 
GLAQCAELCW QLRGEAGKRQ VPGAKVALQH NLGIGGAVVV TLYKMGFPEA ASSFRTHQIE 
AVPTSSASDG FKANLVFKEI EKKLEEEGEQ FVKKIGGIFA FKVKDGPGGK EATWVVDVKN 
GKGSVLPNSD KKADCTITMA DSDFLALMTG KMNPQSAFFQ GKLKITGNMG LAMKLQNLQL 
QPGNAKL

Genular Protein ID: 2345235353

Symbol: E9PLD1_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PLD1

Database IDs:

ARBA 8 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 2 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 366
  • Mass: 39553
  • Checksum: FD7682E738F5337E
  • Sequence:
    • MSSSPWEPAT LRRVFVVGVG MTKFVKPGAE NSRDYPDLAE EAGKKALADA QIPYSAVDQA 
CVGYVFGDST CGQRAIYHSL GMTGIPIINV NNNCATGSTA LFMARQLIQG GVAECVLALG 
FEKMSKGSLG IKFSDRTIPT DKHVDLLINK YGLSAHPVAP QMFGYAGKEH MEKYGTKIEH 
FAKIGWKNHK HSVNNPYSQF QDEYSLDEVM ASKEVFDFLT ILQCCPTSDG AAAAILASEA 
FVQKYGLQSK AVEILAQEMM TDLPSSFEEK SIIKMVGFDM SKEAARKCYE KSGLTPNDID 
VIELHDCFST NELLTYEALG LCPEGQGATL VDRGDNTYGG KWVINPSGGL ISKGHPLGAT 
GGHSCS

Genular Protein ID: 1988497702

Symbol: Q59HG9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59HG9

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 2 Pfam 3 RefSeq 7 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 406
  • Mass: 43549
  • Checksum: D4117254D521F085
  • Sequence:
    • RACVAARGPG FGLQGALVQS PPVSAGSRPR RPPRSRTGAA MSSSPWEPAT LRRVFVVGVG 
MTKFVKPGAE NSRDYPDLAE EAGKKALADA QIPYSAVDQA CVGYVFGDST CGQRAIYHSL 
GMTGIPIINV NNNCATGSTA LFMARQLIQG GVAECVLALG FEKMSKGSLG IKFSDRTIPT 
DKHVDLLINK YGLSAHPVAP QMFGYAGKEH MEKYGTKIEH FAKIGWKNHK HSVNNPYSQF 
QDEYSLDEVM ASKEVFDFLT ILQCCPTSDG AAAAILASEA FVQKYGLQSK AVEILAQEMM 
TDLPSSFEEK SIIKMVGFDM SKEAARKCYE KSGLTPNDID VIELHDCFST NELLTYEALG 
LCPEGQGATL VDRGDNTYGG KWVINPSGGL ISKGHPLGAT GGHSCS

Genular Protein ID: 2851074489

Symbol: B2R761_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R761

Database IDs:

ARBA 34 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 53 DNASU 1 DisGeNET 1 EC 4 EMBL 2 GO 8 Gene3D 2 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 5 RefSeq 1 Rhea 27 SUPFAM 2

Sequence Information:

  • Length: 547
  • Mass: 59022
  • Checksum: D7985485C648A9AA
  • Sequence:
    • MSSSPWEPAT LRRVFVVGVG MTKFVKPGAE NSRDYPDLAE EAGKKALADA QIPYSAVDQA 
CVGYVFGDST CGQRAIYHSL GMTGIPIINV NNNCATGSTA LFMARQLIQG GVAECVLALG 
FEKMSKGSLG IKFSDRTIPT DKHVDLLINK YGLSAHPVAP QMFGYAGKEH MEKYGTKIEH 
FAKIGWKNHK HSVNNPYSQF QDEYSLDEVM ASKEVFDFLT ILRCCPTSDG AAAAILASEA 
FVQKYGLQSK AVEILAQEMM TDLPSSFEEK SIIKMVGFDM SKEAARKCYE KSGLTPNDID 
VIELHDCFST NELLTYEALG LCPEGQGATL VDRGDNTYGG KWVINPSGGL ISKGHPLGAT 
GLAQCAELCW QLRGEAGKRQ VPGAKVALQH NLGIGGAVVV TLYKMGFPEA ASSFRTHQIE 
AVPTSSASDG FKANLVFKEI EKKLEEEGEQ FVKKIGGIFA FKVKDGPGGK EATWVVDVKN 
GKGSVLPNSD KKADCTITMA DSDFLALMTG KMNPQSAFFQ GKLKITGNMG LAMKLQNLQL 
QPGNAKL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.