Details for: SDF2
Gene ID: 6388
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: SDF2
Ensembl ID: ENSG00000132581
Description: stromal cell derived factor 2
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 10.7rCSI 16.37%PRS 45.4
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CSI 8.82rCSI 8.81%PRS 25.4
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CSI 7.74rCSI 11.96%PRS 27.99
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CSI 7.58rCSI 10.32%PRS 41.97
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CSI 7.57rCSI 7.44%PRS 43.64
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CSI 6.13rCSI 5.08%PRS 30.15
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CSI 6.03rCSI 15.58%PRS 27.42
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CSI 5.71rCSI 14.13%PRS 27.92
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CSI 4.46rCSI 3%PRS 37.01
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CSI 4.31rCSI 8.31%PRS 59.48
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CSI 4.06rCSI 13.16%PRS 34.09
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CSI 3.95rCSI 3%PRS 38.7
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CSI 3.91rCSI 3.13%PRS 49.46
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CSI 3.89rCSI 19.53%PRS 38.54
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CSI 3.78rCSI 9.1%PRS 44.94
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CSI 3.72rCSI 5.11%PRS 50.73
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CSI 3.51rCSI 7.87%PRS 19.13
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CSI 3.48rCSI 4.64%PRS 51.46
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CSI 3.45rCSI 3.06%PRS 29.6
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CSI 3.4rCSI 2.36%PRS 35.83
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CSI 3.35rCSI 4.14%PRS 26.33
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CSI 3.31rCSI 3.72%PRS 44.77
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CSI 3.28rCSI 3.59%PRS 32.94
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CSI 3.03rCSI 5.73%PRS 65.59
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CSI 3.01rCSI 2.54%PRS 44.93
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CSI 2.99rCSI 4.09%PRS 33.43
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CSI 2.89rCSI 4.58%PRS 37.99
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CSI 2.78rCSI 4.11%PRS 33.66
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CSI 2.72rCSI 2.46%PRS 27.14
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CSI 2.7rCSI 4.84%PRS 24.89
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CSI 2.68rCSI 5.37%PRS 22.32
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CSI 2.66rCSI 2.21%PRS 28.33
-
CSI 2.57rCSI 3.11%PRS 35.45
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CSI 2.56rCSI 3.26%PRS 34
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CSI 2.55rCSI 4.06%PRS 25.11
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CSI 2.48rCSI 2.44%PRS 31.76
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CSI 2.39rCSI 2.1%PRS 33.75
-
CSI 2.38rCSI 3.48%PRS 38.46
-
CSI 2.31rCSI 3.19%PRS 37.23
-
CSI 2.26rCSI 3.32%PRS 32.09
-
CSI 2.24rCSI 4.21%PRS 51.28
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CSI 2.24rCSI 2.07%PRS 30.77
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CSI 2.2rCSI 2.07%PRS 30.89
-
CSI 2.19rCSI 2.28%PRS 30.41
-
CSI 2.19rCSI 2.1%PRS 30.58
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CSI 2.16rCSI 1.62%PRS 43.68
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CSI 2.15rCSI 4.19%PRS 30.69
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CSI 2.12rCSI 3.05%PRS 43.44
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CSI 2.1rCSI 2.2%PRS 31.44
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CSI 2.09rCSI 3.99%PRS 45.03
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CSI 2.09rCSI 5.99%PRS 43.73
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CSI 2.08rCSI 3.6%PRS 22.93
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CSI 2.08rCSI 2.61%PRS 42.4
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CSI 2.05rCSI 2.5%PRS 36.3
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CSI 2.04rCSI 1.76%PRS 40.58
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CSI 2.04rCSI 1.8%PRS 21.89
-
CSI 2.04rCSI 5.84%PRS 47.6
-
CSI 2.01rCSI 2.99%PRS 33.26
-
CSI 2rCSI 1.58%PRS 35.25
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CSI 1.94rCSI 4.12%PRS 44.23
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CSI 1.91rCSI 9.81%PRS 70.54
-
CSI 1.9rCSI 1.47%PRS 29.14
-
CSI 1.9rCSI 1.99%PRS 27.72
-
CSI 1.84rCSI 5.42%PRS 34.38
-
CSI 1.83rCSI 1.38%PRS 39.95
-
CSI 1.83rCSI 2.79%PRS 37.52
-
CSI 1.81rCSI 1.74%PRS 22.45
-
CSI 1.79rCSI 1.38%PRS 28.09
-
CSI 1.76rCSI 3.2%PRS 43.91
-
CSI 1.76rCSI 1.39%PRS 20.73
-
CSI 1.73rCSI 2.73%PRS 30.18
-
CSI 1.7rCSI 1.83%PRS 27.62
-
CSI 1.68rCSI 2%PRS 48.23
-
CSI 1.67rCSI 1.72%PRS 45.42
-
CSI 1.64rCSI 3.73%PRS 36.62
-
CSI 1.61rCSI 2.6%PRS 41.05
-
CSI 1.61rCSI 1.64%PRS 41.1
-
CSI 1.6rCSI 1.06%PRS 34.1
-
CSI 1.58rCSI 2.02%PRS 28.34
-
CSI 1.56rCSI 2.23%PRS 32.41
-
CSI 1.52rCSI 1.59%PRS 30.39
-
CSI 1.51rCSI 2.22%PRS 31.62
-
CSI 1.51rCSI 3.33%PRS 33.31
-
CSI 1.5rCSI 1.73%PRS 25.8
-
CSI 1.49rCSI 2.04%PRS 32.44
-
CSI 1.48rCSI 1.2%PRS 30.72
-
CSI 1.48rCSI 1.03%PRS 31.26
-
CSI 1.45rCSI 1.71%PRS 33.45
-
CSI 1.45rCSI 1.09%PRS 31.79
-
CSI 1.42rCSI 1.89%PRS 32.68
-
CSI 1.41rCSI 1.22%PRS 36.87
-
CSI 1.38rCSI 2.1%PRS 27.39
-
CSI 1.34rCSI 2.37%PRS 17.95
-
CSI 1.34rCSI 1.16%PRS 32.99
-
CSI 1.34rCSI 1.68%PRS 37.81
-
CSI 1.34rCSI 1.55%PRS 22.27
-
CSI 1.29rCSI 1.19%PRS 35.23
-
CSI 1.28rCSI 2.28%PRS 27.87
-
CSI 1.27rCSI 1.76%PRS 29.86
-
CSI 1.26rCSI 2.01%PRS 25.33
-
CSI 0.1rCSI 0.4%PRS 19.4%
-
CSI 0.2rCSI 1.0%PRS 41.7%
-
CSI 0.2rCSI 5.5%PRS 63.8%
-
CSI 0.2rCSI 5.5%PRS 51.5%
-
CSI 0.3rCSI 1.9%PRS 40.7%
-
CSI 0.4rCSI 1.9%PRS 39.1%
-
CSI 0.4rCSI 3.1%PRS 49.6%
-
CSI 0.4rCSI 1.7%PRS 47.9%
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CSI 0.4rCSI 1.7%PRS 46.1%
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CSI 0.4rCSI 1.6%PRS 17.6%
-
CSI 0.6rCSI 2.0%PRS 44.3%
-
CSI 0.6rCSI 1.7%PRS 32.7%
-
CSI 0.6rCSI 3.5%PRS 41.1%
-
CSI 0.6rCSI 1.2%PRS 54.2%
-
CSI 0.6rCSI 2.8%PRS 28.7%
-
CSI 0.6rCSI 0.8%PRS 19.2%
-
CSI 0.7rCSI 1.8%PRS 45.6%
-
CSI 0.7rCSI 4.7%PRS 50.8%
-
CSI 0.7rCSI 1.1%PRS 30.5%
-
CSI 0.7rCSI 1.7%PRS 41.9%
-
CSI 0.8rCSI 1.1%PRS 44.6%
-
CSI 0.8rCSI 2.5%PRS 38.8%
-
CSI 0.8rCSI 3.5%PRS 26.2%
-
CSI 0.8rCSI 1.5%PRS 22.2%
-
CSI 0.8rCSI 2.9%PRS 46.3%
-
CSI 0.9rCSI 0.9%PRS 34.7%
-
CSI 0.9rCSI 1.4%PRS 23.0%
-
CSI 0.9rCSI 2.4%PRS 74.2%
-
CSI 0.9rCSI 3.5%PRS 50.3%
-
CSI 0.9rCSI 2.3%PRS 28.5%
-
CSI 0.9rCSI 1.1%PRS 28.7%
-
CSI 0.9rCSI 1.5%PRS 20.2%
-
CSI 1.0rCSI 3.9%PRS 46.0%
-
CSI 1.0rCSI 4.1%PRS 53.5%
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CSI 1.0rCSI 0.9%PRS 34.5%
-
CSI 1.0rCSI 1.8%PRS 51.0%
-
CSI 1.1rCSI 2.1%PRS 46.9%
-
CSI 1.1rCSI 3.1%PRS 48.3%
-
CSI 1.1rCSI 0.9%PRS 29.8%
-
CSI 1.1rCSI 1.5%PRS 25.8%
-
CSI 1.1rCSI 1.5%PRS 41.5%
-
CSI 1.1rCSI 1.9%PRS 38.5%
-
CSI 1.1rCSI 2.5%PRS 34.6%
-
CSI 1.1rCSI 2.5%PRS 27.5%
-
CSI 1.2rCSI 1.9%PRS 32.5%
-
CSI 1.2rCSI 1.8%PRS 30.0%
-
CSI 1.2rCSI 1.9%PRS 33.7%
-
CSI 1.3rCSI 2.1%PRS 18.5%
-
CSI 1.3rCSI 1.4%PRS 52.7%
-
CSI 1.3rCSI 2.0%PRS 25.3%
-
CSI 1.3rCSI 1.8%PRS 29.9%
-
CSI 1.3rCSI 2.3%PRS 27.9%
-
CSI 1.3rCSI 1.2%PRS 35.2%
-
CSI 1.3rCSI 1.6%PRS 22.3%
-
CSI 1.3rCSI 1.7%PRS 37.8%
-
CSI 1.3rCSI 1.2%PRS 33.0%
-
CSI 1.3rCSI 2.4%PRS 18.0%
-
CSI 1.4rCSI 2.1%PRS 27.4%
-
CSI 1.4rCSI 1.2%PRS 36.9%
-
CSI 1.4rCSI 1.9%PRS 32.7%
-
CSI 1.5rCSI 1.1%PRS 31.8%
-
CSI 1.5rCSI 1.7%PRS 33.5%
-
CSI 1.5rCSI 1.0%PRS 31.3%
-
CSI 1.5rCSI 1.2%PRS 30.7%
-
CSI 1.5rCSI 2.0%PRS 32.4%
-
CSI 1.5rCSI 1.7%PRS 25.8%
-
CSI 1.5rCSI 3.3%PRS 33.3%
-
CSI 1.5rCSI 2.2%PRS 31.6%
-
CSI 1.5rCSI 1.6%PRS 30.4%
-
CSI 1.6rCSI 2.2%PRS 32.4%
-
CSI 1.6rCSI 2.0%PRS 28.3%
-
CSI 1.6rCSI 1.1%PRS 34.1%
-
CSI 1.6rCSI 1.6%PRS 41.1%
-
CSI 1.6rCSI 2.6%PRS 41.1%
-
CSI 1.6rCSI 3.7%PRS 36.6%
-
CSI 1.7rCSI 1.7%PRS 45.4%
-
CSI 1.7rCSI 2.0%PRS 48.2%
-
CSI 1.7rCSI 1.8%PRS 27.6%
-
CSI 1.7rCSI 2.7%PRS 30.2%
-
CSI 1.8rCSI 1.4%PRS 20.7%
-
CSI 1.8rCSI 3.2%PRS 43.9%
-
CSI 1.8rCSI 1.4%PRS 28.1%
-
CSI 1.8rCSI 1.7%PRS 22.5%
-
CSI 1.8rCSI 2.8%PRS 37.5%
-
CSI 1.8rCSI 1.4%PRS 40.0%
-
CSI 1.8rCSI 5.4%PRS 34.4%
-
CSI 1.9rCSI 2.0%PRS 27.7%
-
CSI 1.9rCSI 1.5%PRS 29.1%
-
CSI 1.9rCSI 9.8%PRS 70.5%
-
CSI 1.9rCSI 4.1%PRS 44.2%
-
CSI 2.0rCSI 1.6%PRS 35.3%
-
CSI 2.0rCSI 3.0%PRS 33.3%
-
CSI 2.0rCSI 5.8%PRS 47.6%
-
CSI 2.0rCSI 1.8%PRS 21.9%
-
CSI 2.0rCSI 1.8%PRS 40.6%
-
CSI 2.1rCSI 2.5%PRS 36.3%
-
CSI 2.1rCSI 2.6%PRS 42.4%
-
CSI 2.1rCSI 3.6%PRS 22.9%
-
CSI 2.1rCSI 6.0%PRS 43.7%
-
CSI 2.1rCSI 4.0%PRS 45.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 438341786
Symbol: SDF2_HUMAN
Name: Stromal cell-derived factor 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8918255
Title: Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method.
PubMed ID: 8918255
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 211
- Mass: 23026
- Checksum: 5EFC91C62E7B61E9
- Sequence:
MAVVPLLLLG GLWSAVGASS LGVVTCGSVV KLLNTRHNVR LHSHDVRYGS GSGQQSVTGV TSVDDSNSYW RIRGKSATVC ERGTPIKCGQ PIRLTHVNTG RNLHSHHFTS PLSGNQEVSA FGEEGEGDYL DDWTVLCNGP YWVRDGEVRF KHSSTEVLLS VTGEQYGRPI SGQKEVHGMA QPSQNNYWKA MEGIFMKPSE LLKAEAHHAE L