Details for: SMARCA2

Gene ID: 6595

Symbol: SMARCA2

Ensembl ID: ENSG00000080503

Description: SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 529.1709
    Cell Significance Index: -82.3100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 302.7479
    Cell Significance Index: -76.7900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 198.3019
    Cell Significance Index: -81.6900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 177.0515
    Cell Significance Index: -83.5900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 161.7941
    Cell Significance Index: -65.7300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 148.1380
    Cell Significance Index: -76.2000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 69.2176
    Cell Significance Index: -66.0900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 67.8208
    Cell Significance Index: -83.6200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 28.1575
    Cell Significance Index: -75.4300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 25.5840
    Cell Significance Index: -78.5800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 21.2941
    Cell Significance Index: -84.0300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 19.5560
    Cell Significance Index: -42.8000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.1997
    Cell Significance Index: 1147.6800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 2.6376
    Cell Significance Index: 162.1200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.6044
    Cell Significance Index: 522.4400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.9655
    Cell Significance Index: 38.3600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.8040
    Cell Significance Index: 43.2700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.7990
    Cell Significance Index: 93.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.6545
    Cell Significance Index: 106.7400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.6237
    Cell Significance Index: 71.8200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.4759
    Cell Significance Index: 55.8900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.4730
    Cell Significance Index: 113.0400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.4245
    Cell Significance Index: 39.8100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.2980
    Cell Significance Index: 897.7400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.2713
    Cell Significance Index: 85.4800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9320
    Cell Significance Index: 55.9500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8856
    Cell Significance Index: 159.6500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.7726
    Cell Significance Index: 20.6300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.7009
    Cell Significance Index: 445.1600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6818
    Cell Significance Index: 301.4200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6661
    Cell Significance Index: 91.4800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6546
    Cell Significance Index: 80.4900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6128
    Cell Significance Index: 334.6700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5454
    Cell Significance Index: 25.4300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.5153
    Cell Significance Index: 11.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4382
    Cell Significance Index: 825.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.3862
    Cell Significance Index: 712.3000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3653
    Cell Significance Index: 6.2600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3472
    Cell Significance Index: 313.4700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.3337
    Cell Significance Index: 4.8000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3098
    Cell Significance Index: 8.9300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.3013
    Cell Significance Index: 463.8800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2959
    Cell Significance Index: 37.9300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1920
    Cell Significance Index: 38.1000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1148
    Cell Significance Index: 5.3900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1108
    Cell Significance Index: 21.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0951
    Cell Significance Index: 43.1800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0936
    Cell Significance Index: 127.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0269
    Cell Significance Index: 1.5100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0141
    Cell Significance Index: -10.3400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0186
    Cell Significance Index: -3.1800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0431
    Cell Significance Index: -31.9300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0440
    Cell Significance Index: -6.4000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0450
    Cell Significance Index: -5.8100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0573
    Cell Significance Index: -9.3200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0602
    Cell Significance Index: -2.7300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0641
    Cell Significance Index: -4.7800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0751
    Cell Significance Index: -46.8900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0802
    Cell Significance Index: -7.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0827
    Cell Significance Index: -46.6700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0868
    Cell Significance Index: -65.7100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1163
    Cell Significance Index: -13.7100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1597
    Cell Significance Index: -5.6100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.2073
    Cell Significance Index: -14.3400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2142
    Cell Significance Index: -5.7300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2164
    Cell Significance Index: -45.5800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2203
    Cell Significance Index: -22.5100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2546
    Cell Significance Index: -73.2600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3042
    Cell Significance Index: -8.6800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3291
    Cell Significance Index: -4.9600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3540
    Cell Significance Index: -41.2600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3611
    Cell Significance Index: -41.2200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4244
    Cell Significance Index: -10.9100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4329
    Cell Significance Index: -45.0800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.4448
    Cell Significance Index: -6.2200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.4487
    Cell Significance Index: -23.3100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5179
    Cell Significance Index: -36.6300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5220
    Cell Significance Index: -59.8000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5784
    Cell Significance Index: -30.3700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5821
    Cell Significance Index: -36.6900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.7058
    Cell Significance Index: -14.9800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8284
    Cell Significance Index: -65.6100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.8947
    Cell Significance Index: -18.5600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.8994
    Cell Significance Index: -20.7800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.9081
    Cell Significance Index: -12.3900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.9395
    Cell Significance Index: -25.1800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.9716
    Cell Significance Index: -16.2600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.9916
    Cell Significance Index: -11.8200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.0331
    Cell Significance Index: -20.7400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.0732
    Cell Significance Index: -21.2200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.1211
    Cell Significance Index: -18.8900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.1471
    Cell Significance Index: -36.7400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.1529
    Cell Significance Index: -16.5100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.1598
    Cell Significance Index: -10.6800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1946
    Cell Significance Index: -73.2400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -1.2241
    Cell Significance Index: -33.3200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -1.2422
    Cell Significance Index: -16.1100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.3076
    Cell Significance Index: -42.8100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.3143
    Cell Significance Index: -41.8600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.3465
    Cell Significance Index: -35.4100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SMARCA2 is a member of the SWI/SNF family of chromatin-remodeling enzymes, which are crucial for regulating gene expression by modifying chromatin structure. The SMARCA2 gene encodes a catalytic subunit that is essential for the activity of the SWI/SNF complex. This complex is composed of multiple subunits, including SMARCA2, SMARCAL1, and SMARCAL2, which work together to remove histone nucleosomes and facilitate the recruitment of transcriptional activators. The SMARCA2 gene is highly expressed in various cell types, including neurons, astrocytes, and syncytiotrophoblast cells, and is involved in regulating gene expression during development, cell growth, and differentiation. **Pathways and Functions** The SMARCA2 gene is involved in various cellular processes, including: 1. **Chromatin remodeling**: SMARCA2 plays a crucial role in removing histone nucleosomes, thereby allowing for increased access to DNA and the recruitment of transcriptional activators. 2. **Gene expression regulation**: The SMARCA2 gene is involved in regulating gene expression by modifying chromatin structure and facilitating the recruitment of transcriptional activators. 3. **Cell growth and differentiation**: SMARCA2 is involved in regulating cell growth and differentiation by controlling the expression of genes involved in these processes. 4. **DNA damage response**: The SMARCA2 gene is involved in regulating the response to DNA damage by controlling the expression of genes involved in DNA repair. 5. **Transcriptional regulation**: SMARCA2 is involved in regulating transcription by interacting with transcriptional activators and repressors. **Clinical Significance** Mutations in the SMARCA2 gene have been implicated in various cancers, including: 1. **Breast cancer**: SMARCA2 mutations have been identified in a subset of breast cancers, particularly those with BRCA1 mutations. 2. **Ovarian cancer**: SMARCA2 mutations have been identified in a subset of ovarian cancers, particularly those with BRCA1 mutations. 3. **Prostate cancer**: SMARCA2 mutations have been identified in a subset of prostate cancers, particularly those with BRCA2 mutations. 4. **Other cancers**: SMARCA2 mutations have also been identified in other cancers, including colon, lung, and pancreatic cancers. In addition to its role in cancer, the SMARCA2 gene is also involved in various other diseases, including: 1. **Neurological disorders**: SMARCA2 mutations have been identified in a subset of neurological disorders, including frontotemporal dementia and amyotrophic lateral sclerosis. 2. **Neonatal cancer**: SMARCA2 mutations have been identified in a subset of neonatal cancers, particularly those with BRCA1 mutations. Overall, the SMARCA2 gene plays a critical role in regulating gene expression and maintaining genome stability, and its dysfunction has been implicated in various diseases, including cancer and neurological disorders.

Genular Protein ID: 812409638

Symbol: SMCA2_HUMAN

Name: Probable global transcription activator SNF2L2

UniProtKB Accession Codes:

P51531 B1ALG3 B1ALG4 D3DRH4 D3DRH5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CORUM 1 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 18 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 8 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 43 Gene3D 5 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 16 PDBsum 16 PIR 2 PRINTS 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 7 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 4 RefSeq 4 SASBDB 1 SIGNOR 1 SMART 7 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8223438

Title: A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

PubMed ID: 8223438

DOI: 10.1002/j.1460-2075.1993.tb06112.x

PubMed ID: 8208605

Title: Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

PubMed ID: 8208605

DOI: 10.1093/nar/22.10.1815

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 11259672

Title: The human brm protein is cleaved during apoptosis: the role of cathepsin G.

PubMed ID: 11259672

DOI: 10.1073/pnas.071057398

PubMed ID: 15075294

Title: TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival.

PubMed ID: 15075294

DOI: 10.1101/gad.1180204

PubMed ID: 15107404

Title: Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity.

PubMed ID: 15107404

DOI: 10.1101/gad.1183304

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18765789

Title: Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.

PubMed ID: 18765789

DOI: 10.1101/gad.471408

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19363039

Title: Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia.

PubMed ID: 19363039

DOI: 10.1093/hmg/ddp166

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20111005

Title: Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.

PubMed ID: 20111005

DOI: 10.1038/emboj.2010.3

PubMed ID: 20460684

Title: Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.

PubMed ID: 20460684

DOI: 10.1074/jbc.m109.087783

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22952240

Title: SWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functions.

PubMed ID: 22952240

DOI: 10.1074/jbc.r111.309302

PubMed ID: 22426308

Title: Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

PubMed ID: 22426308

DOI: 10.1038/ng.2219

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 26030138

Title: Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

PubMed ID: 26030138

DOI: 10.1371/journal.pone.0128558

PubMed ID: 26601204

Title: Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics.

PubMed ID: 26601204

DOI: 10.1126/sciadv.1500447

PubMed ID: 23906836

Title: A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling.

PubMed ID: 23906836

DOI: 10.1093/hmg/ddt366

PubMed ID: 22366787

Title: Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome.

PubMed ID: 22366787

DOI: 10.1038/ng.1105

PubMed ID: 27665729

Title: New SMARCA2 mutation in a patient with Nicolaides-Baraitser syndrome and myoclonic astatic epilepsy.

PubMed ID: 27665729

DOI: 10.1002/ajmg.a.37935

PubMed ID: 32694869

Title: De novo SMARCA2 variants clustered outside the helicase domain cause a new recognizable syndrome with intellectual disability and blepharophimosis distinct from Nicolaides-Baraitser syndrome.

PubMed ID: 32694869

DOI: 10.1038/s41436-020-0898-y

Sequence Information:

  • Length: 1590
  • Mass: 181279
  • Checksum: CE69BBB287D35AB5
  • Sequence:
    • MSTPTDPGAM PHPGPSPGPG PSPGPILGPS PGPGPSPGSV HSMMGPSPGP PSVSHPMPTM 
GSTDFPQEGM HQMHKPIDGI HDKGIVEDIH CGSMKGTGMR PPHPGMGPPQ SPMDQHSQGY 
MSPHPSPLGA PEHVSSPMSG GGPTPPQMPP SQPGALIPGD PQAMSQPNRG PSPFSPVQLH 
QLRAQILAYK MLARGQPLPE TLQLAVQGKR TLPGLQQQQQ QQQQQQQQQQ QQQQQQQQPQ 
QQPPQPQTQQ QQQPALVNYN RPSGPGPELS GPSTPQKLPV PAPGGRPSPA PPAAAQPPAA 
AVPGPSVPQP APGQPSPVLQ LQQKQSRISP IQKPQGLDPV EILQEREYRL QARIAHRIQE 
LENLPGSLPP DLRTKATVEL KALRLLNFQR QLRQEVVACM RRDTTLETAL NSKAYKRSKR 
QTLREARMTE KLEKQQKIEQ ERKRRQKHQE YLNSILQHAK DFKEYHRSVA GKIQKLSKAV 
ATWHANTERE QKKETERIEK ERMRRLMAED EEGYRKLIDQ KKDRRLAYLL QQTDEYVANL 
TNLVWEHKQA QAAKEKKKRR RRKKKAEENA EGGESALGPD GEPIDESSQM SDLPVKVTHT 
ETGKVLFGPE APKASQLDAW LEMNPGYEVA PRSDSEESDS DYEEEDEEEE SSRQETEEKI 
LLDPNSEEVS EKDAKQIIET AKQDVDDEYS MQYSARGSQS YYTVAHAISE RVEKQSALLI 
NGTLKHYQLQ GLEWMVSLYN NNLNGILADE MGLGKTIQTI ALITYLMEHK RLNGPYLIIV 
PLSTLSNWTY EFDKWAPSVV KISYKGTPAM RRSLVPQLRS GKFNVLLTTY EYIIKDKHIL 
AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH YVAPRRILLT GTPLQNKLPE LWALLNFLLP 
TIFKSCSTFE QWFNAPFAMT GERVDLNEEE TILIIRRLHK VLRPFLLRRL KKEVESQLPE 
KVEYVIKCDM SALQKILYRH MQAKGILLTD GSEKDKKGKG GAKTLMNTIM QLRKICNHPY 
MFQHIEESFA EHLGYSNGVI NGAELYRASG KFELLDRILP KLRATNHRVL LFCQMTSLMT 
IMEDYFAFRN FLYLRLDGTT KSEDRAALLK KFNEPGSQYF IFLLSTRAGG LGLNLQAADT 
VVIFDSDWNP HQDLQAQDRA HRIGQQNEVR VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ 
AGMFDQKSSS HERRAFLQAI LEHEEENEEE DEVPDDETLN QMIARREEEF DLFMRMDMDR 
RREDARNPKR KPRLMEEDEL PSWIIKDDAE VERLTCEEEE EKIFGRGSRQ RRDVDYSDAL 
TEKQWLRAIE DGNLEEMEEE VRLKKRKRRR NVDKDPAKED VEKAKKRRGR PPAEKLSPNP 
PKLTKQMNAI IDTVINYKDR CNVEKVPSNS QLEIEGNSSG RQLSEVFIQL PSRKELPEYY 
ELIRKPVDFK KIKERIRNHK YRSLGDLEKD VMLLCHNAQT FNLEGSQIYE DSIVLQSVFK 
SARQKIAKEE ESEDESNEEE EEEDEEESES EAKSVKVKIK LNKKDDKGRD KGKGKKRPNR 
GKAKPVVSDF DSDEEQDERE QSEGSGTDDE

Genular Protein ID: 1263460578

Symbol: F6T8Q0_HUMAN

Name: N/A

UniProtKB Accession Codes:

F6T8Q0

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 248
  • Mass: 28895
  • Checksum: 19A66DF2CA2CB948
  • Sequence:
    • MWLAIEDGNL EEMEEEVRLK KRKRRRNVDK DPAKEDVEKA KKRRGRPPAE KLSPNPPKLT 
KQMNAIIDTV INYKDSSGRQ LSEVFIQLPS RKELPEYYEL IRKPVDFKKI KERIRNHKYR 
SLGDLEKDVM LLCHNAQTFN LEGSQIYEDS IVLQSVFKSA RQKIAKEEES EDESNEEEEE 
EDEEESESEA KSVKVKIKLN KKDDKGRDKG KGKKRPNRGK AKPVVSDFDS DEEQDEREQS 
EGSGTDDE

Genular Protein ID: 4008992530

Symbol: B1ALF6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B1ALF6

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 278
  • Mass: 31979
  • Checksum: 5766E7798DBF003B
  • Sequence:
    • MLMKRLAARC FAGLLILSPL TVISDSRPAD SGKAIEDGNL EEMEEEVRLK KRKRRRNVDK 
DPAKEDVEKA KKRRGRPPAE KLSPNPPKLT KQMNAIIDTV INYKDSSGRQ LSEVFIQLPS 
RKELPEYYEL IRKPVDFKKI KERIRNHKYR SLGDLEKDVM LLCHNAQTFN LEGSQIYEDS 
IVLQSVFKSA RQKIAKEEES EDESNEEEEE EDEEESESEA KSVKVKIKLN KKDDKGRDKG 
KGKKRPNRGK AKPVVSDFDS DEEQDEREQS EGSGTDDE

Genular Protein ID: 2713643219

Symbol: Q56A76_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q56A76

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 2 SAM 1 SMART 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 298
  • Mass: 31141
  • Checksum: 61E0203031C27DF5
  • Sequence:
    • MSTPTDPGAM PHPGPSPGPG PSPGPILGPS PGPGPSPGSV HSMMGPSPGP PSVSHPMPTM 
GSTDFPQEGM HQMHKPIDGI HDKGIVEDIH CGSMKGTGMR PPHPGMGPPQ SPMDQHSQGY 
MSPHPSPLGA PEHVSSPMSG GGPTPPQMPP SQPGALIPGD PQAMSQPNRG PSPFSPVQLH 
QLRAQILAYK MLARGQPLPE TLQLAVQGKR TLPGLQQQQQ QQQQQQQQQQ QQQQQQQQPQ 
QQPPQPQTQQ QQQPALVNYN RPSGPGPELS GPSTPQKLPV PAPGGRPSPA PPAAAQPP

Genular Protein ID: 814879460

Symbol: F6VDE0_HUMAN

Name: N/A

UniProtKB Accession Codes:

F6VDE0

Database IDs:

ARBA 8 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 9 Gene3D 5 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 14 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 11 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 7 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 7 SMR 1 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1514
  • Mass: 172592
  • Checksum: 77255AC165E51BE0
  • Sequence:
    • MSTPTDPGAM PHPGPSPGPG PSPGPILGPS PGPGPSPGSV HSMMGPSPGP PSVSHPMPTM 
GSTDFPQEGM HQMHKPIDGI HDKGIVEDIH CGSMKGTGMR PPHPGMGPPQ SPMDQHSQGY 
MSPHPSPLGA PEHVSSPMSG GGPTPPQMPP SQPGALIPGD PQAMSQPNRG PSPFSPVQLH 
QLRAQILAYK MLARGQPLPE TLQLAVQGKR TLPGLQQQQQ QQQQQQQQQQ QQQQQQQQPQ 
QQPPQPQTQQ QQQPALVNYN RPSGPGPELS GPSTPQKLPV PAPGGRPSPA PPAAAQPPAA 
AVPGPSVPQP APGQPSPVLQ LQQKQSRISP IQKPQGLDPV EILQEREYRL QARIAHRIQE 
LENLPGSLPP DLRTKATVEL KALRLLNFQR QLRQEVVACM RRDTTLETAL NSKAYKRSKR 
QTLREARMTE KLEKQQKIEQ ERKRRQKHQE YLNSILQHAK DFKEYHRSVA GKIQKLSKAV 
ATWHANTERE QKKETERIEK ERMRRLMAED EEGYRKLIDQ KKDRRLAYLL QQTDEYVANL 
TNLVWEHKQA QAAKEKKKRR RRKKKAEENA EGGESALGPD GEPIDESSQM SDLPVKVTHT 
ETGKVLFGPE APKASQLDAW LEMNPGYEVA PRSDSEESDS DYEEEDEEEE SSRQETEEKI 
LLDPNSEEVS EKDAKQIIET AKQDVDDEYS MQYSARGSQS YYTVAHAISE RVEKQSALLI 
NGTLKHYQLQ GLEWMVSLYN NNLNGILADE MGLGKTIQTI ALITYLMEHK RLNGPYLIIV 
PLSTLSNWTY EFDKWAPSVV KISYKGTPAM RRSLVPQLRS GKFNVLLTTY EYIIKDKHIL 
AKIRWKYMIV DEGHRMKNHH CKLTQVDLNE EETILIIRRL HKVLRPFLLR RLKKEVESQL 
PEKVEYVIKC DMSALQKILY RHMQAKGILL TDGSEKDKKG KGGAKTLMNT IMQLRKICNH 
PYMFQHIEES FAEHLGYSNG VINGAELYRA SGKFELLDRI LPKLRATNHR VLLFCQMTSL 
MTIMEDYFAF RNFLYLRLDG TTKSEDRAAL LKKFNEPGSQ YFIFLLSTRA GGLGLNLQAA 
DTVVIFDSDW NPHQDLQAQD RAHRIGQQNE VRVLRLCTVN SVEEKILAAA KYKLNVDQKV 
IQAGMFDQKS SSHERRAFLQ AILEHEEENE EEDEVPDDET LNQMIARREE EFDLFMRMDM 
DRRREDARNP KRKPRLMEED ELPSWIIKDD AEVERLTCEE EEEKIFGRGS RQRRDVDYSD 
ALTEKQWLRA IEDGNLEEME EEVRLKKRKR RRNVDKDPAK EDVEKAKKRR GRPPAEKLSP 
NPPKLTKQMN AIIDTVINYK DSSGRQLSEV FIQLPSRKEL PEYYELIRKP VDFKKIKERI 
RNHKYRSLGD LEKDVMLLCH NAQTFNLEGS QIYEDSIVLQ SVFKSARQKI AKEEESEDES 
NEEEEEEDEE ESESEAKSVK VKIKLNKKDD KGRDKGKGKK RPNRGKAKPV VSDFDSDEEQ 
DEREQSEGSG TDDE

Genular Protein ID: 1705852360

Symbol: B4DNT1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DNT1 F6XG14

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 3 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 2 SAM 2 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 276
  • Mass: 31735
  • Checksum: E7B935AD63F97B42
  • Sequence:
    • MKRLAARCFA GLLILSPLTV ISDSRPADSG KAIEDGNLEE MEEEVRLKKR KRRRNVDKDP 
AKEDVEKAKK RRGRPPAEKL SPNPPKLTKQ MNAIIDTVIN YKDSSGRQLS EVFIQLPSRK 
ELPEYYELIR KPVDFKKIKE RIRNHKYRSL GDLEKDVMLL CHNAQTFNLE GSQIYEDSIV 
LQSVFKSARQ KIAKEEESED ESNEEEEEED EEESESEAKS VKVKIKLNKK DDKGRDKGKG 
KKRPNRGKAK PVVSDFDSDE EQDEREQSEG SGTDDE

Genular Protein ID: 1422371905

Symbol: Q8N9Q1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8N9Q1

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 4 SAM 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 278
  • Mass: 31993
  • Checksum: A7BD8AC0C9789669
  • Sequence:
    • MLMKRLAARC FAGLLILSPL TVISDSRPAD SGKAIEDGDL EEMEEEVRLK KRKRRRNVDK 
DPAKEDVEKA KKRRGRPPAE KLSPNPPKLT KQMNAIIDTV INYKDSSGRQ LSEVFIQLPS 
RKELPEYYEL IRKPVDFKKI KERIRNHKYR SLGDLEKDVM LLCHNAQTFN LEGSQIYEDS 
IVLQSVFKSA RQKIAKEEES EDESNEEEEE KDEEESESEA KSVKVKIKLN KKDEKGRDKG 
KGKKRPNRGK AKPVVSDFDS DEEQDEREQS EGSGTDDE

Genular Protein ID: 1214930230

Symbol: B4DSC8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DSC8

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 3 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 3 SUPFAM 2

Sequence Information:

  • Length: 715
  • Mass: 83454
  • Checksum: 164EFED89D0591D8
  • Sequence:
    • MVSLYNNNLN GILADEMGLG KTIQTIALIT YLMEHKRLNG PYLIIVPLST LSNWTYEFDK 
WAPSVVKISY KGTPAMRRSL VPQLRSGKFN VLLTTYEYII KDKHILAKIR WKYMIVDEGH 
RMKNHHCKLT QVLNTHYVAP RRILLTGTPL QNKLPELWAL LNFLLPTIFK SCSTFEQWFN 
APFAMTGERV DLNEEETILI IRRLHKVLRP FLLRRLKKEV ESQLPEKVEY VIKCDMSALQ 
KILYRHMQAK GILLTDGSEK DKKGKGGAKT LMNTIMQLRK ICNHPYMFQH IEESFAEHLG 
YSNGVINGAE LYRASGKFEL LDRILPKLRA TNHRVLLFCQ MTSLMTIMED YFAFRNFLYL 
RLDGTTKSED RAALLKKFNE PGSQYFIFLL STRAGGLGLN LQAADTVVIF DSDWNPHQDL 
QAQDRAHRIG QQNEVRVLRL CTVNSVEEKI LAAAKYKLNV DQKVIQAGMF DQKSSSHERR 
AFLQAILEHE EENEEEDEVP DDETLNQMIA RREEEFDLFM RMDMDRRRED ARNPKRKPRL 
MEEDELPSWI IKDDAEVGRL TCEEEEEKIF GRGSRQRRDV DYSDALTEKQ WLRAIEDGNL 
EEMEEEVRLK KRKRRRNVDK DPAKEDVEKA KKRRGRPPAE KLSPNPPKLT KQMNAIIDTV 
INYKDRCNVE KVPSNSQLEI EGNSSGRQLS EVFIQLPSRK ELPEYYELIR KPVDF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.