Details for: DENND2B

Gene ID: 6764

Symbol: DENND2B

Ensembl ID: ENSG00000166444

Description: DENN domain containing 2B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 275.1611
    Cell Significance Index: -42.8000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 169.4899
    Cell Significance Index: -42.9900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 90.8046
    Cell Significance Index: -36.8900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 90.0825
    Cell Significance Index: -42.5300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 63.6790
    Cell Significance Index: -42.7300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 38.5968
    Cell Significance Index: -36.8500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 34.7133
    Cell Significance Index: -42.8000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.7753
    Cell Significance Index: -42.5200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 6.0500
    Cell Significance Index: 72.1200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.2594
    Cell Significance Index: 91.0900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.6977
    Cell Significance Index: 151.3800
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.5629
    Cell Significance Index: 22.7500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.2995
    Cell Significance Index: 44.8800
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.2060
    Cell Significance Index: 23.0300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.1680
    Cell Significance Index: 29.5800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.0916
    Cell Significance Index: 131.8300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.9432
    Cell Significance Index: 149.1200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 1.3427
    Cell Significance Index: 67.8600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2971
    Cell Significance Index: 257.4200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 1.2104
    Cell Significance Index: 18.2400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2060
    Cell Significance Index: 241.9300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1662
    Cell Significance Index: 189.6800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.0155
    Cell Significance Index: 460.9200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9616
    Cell Significance Index: 132.0600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8641
    Cell Significance Index: 23.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8547
    Cell Significance Index: 24.6300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8474
    Cell Significance Index: 38.4100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7329
    Cell Significance Index: 79.7200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.7187
    Cell Significance Index: 1353.3200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6946
    Cell Significance Index: 41.7000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6808
    Cell Significance Index: 14.7500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6601
    Cell Significance Index: 15.2500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6567
    Cell Significance Index: 235.5500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.6182
    Cell Significance Index: 64.3700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6160
    Cell Significance Index: 32.0000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4797
    Cell Significance Index: 11.9900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4398
    Cell Significance Index: 79.2800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.3680
    Cell Significance Index: 678.6700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3675
    Cell Significance Index: 45.1900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3458
    Cell Significance Index: 34.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3437
    Cell Significance Index: 16.0300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3090
    Cell Significance Index: 168.7500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2659
    Cell Significance Index: 50.6100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.2238
    Cell Significance Index: 1.8800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2178
    Cell Significance Index: 196.6900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1980
    Cell Significance Index: 304.7600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1669
    Cell Significance Index: 7.8500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.1592
    Cell Significance Index: 18.2400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.1422
    Cell Significance Index: 2.1000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1389
    Cell Significance Index: 88.2000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1344
    Cell Significance Index: 7.0000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1140
    Cell Significance Index: 14.6200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0772
    Cell Significance Index: 34.1200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0735
    Cell Significance Index: 1.2600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0667
    Cell Significance Index: 1.7600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0582
    Cell Significance Index: 1.6700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0470
    Cell Significance Index: 0.6700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0469
    Cell Significance Index: 63.7800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0012
    Cell Significance Index: -0.0200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0070
    Cell Significance Index: -0.3700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0186
    Cell Significance Index: -14.1000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0304
    Cell Significance Index: -3.9300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0329
    Cell Significance Index: -5.6200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0384
    Cell Significance Index: -28.1500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0397
    Cell Significance Index: -29.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0531
    Cell Significance Index: -1.7000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0658
    Cell Significance Index: -37.1000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0677
    Cell Significance Index: -42.2800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0726
    Cell Significance Index: -10.5500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1148
    Cell Significance Index: -11.7300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1335
    Cell Significance Index: -38.4100
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.1507
    Cell Significance Index: -0.9300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2014
    Cell Significance Index: -42.4300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2150
    Cell Significance Index: -7.5600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2545
    Cell Significance Index: -3.6500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3625
    Cell Significance Index: -42.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4294
    Cell Significance Index: -30.3700
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: -0.4359
    Cell Significance Index: -5.0200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4373
    Cell Significance Index: -32.6000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4529
    Cell Significance Index: -17.1500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4725
    Cell Significance Index: -16.4200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4773
    Cell Significance Index: -9.9900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4843
    Cell Significance Index: -21.4200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4963
    Cell Significance Index: -30.4300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5003
    Cell Significance Index: -39.6200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5126
    Cell Significance Index: -10.8800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5538
    Cell Significance Index: -10.9500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6123
    Cell Significance Index: -13.0400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6473
    Cell Significance Index: -41.7600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7073
    Cell Significance Index: -18.1800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7718
    Cell Significance Index: -25.2700
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.7750
    Cell Significance Index: -11.7900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7787
    Cell Significance Index: -24.8000
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.8113
    Cell Significance Index: -11.3800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.8331
    Cell Significance Index: -18.0000
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.8422
    Cell Significance Index: -10.8000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.8585
    Cell Significance Index: -13.6200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.8866
    Cell Significance Index: -15.3300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.9109
    Cell Significance Index: -13.4500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.9263
    Cell Significance Index: -32.4500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DENND2B is a member of the DENN domain-containing protein family, characterized by the presence of a conserved DENN domain. This domain is crucial for protein-protein interactions, modulating the activity of various cellular processes. DENND2B is predominantly expressed in cells of the cardiovascular system, including cardiac muscle cells, smooth muscle cells, and vascular endothelial cells. Its expression is also observed in ciliary muscle cells, anterior lens cells, and pigmented epithelial cells, highlighting its widespread involvement in cellular homeostasis. **Pathways and Functions:** DENND2B is implicated in several critical cellular pathways, including: 1. **Guanyl-nucleotide exchange factor activity**: DENND2B modulates the activity of guanyl-nucleotide exchange factors, which regulate the exchange of GDP for GTP on small GTPases. This process is essential for various cellular functions, including cell growth, differentiation, and survival. 2. **Rab regulation of trafficking**: DENND2B interacts with Rab GTPases, which are key regulators of vesicle-mediated transport and membrane trafficking. This interaction modulates the activity of Rab GTPases, influencing the trafficking of proteins and lipids within cells. 3. **Positive regulation of ERK1/2 cascade**: DENND2B is involved in the positive regulation of the ERK1/2 signaling pathway, which plays a crucial role in cell proliferation, differentiation, and survival. 4. **Membrane trafficking**: DENND2B modulates the activity of proteins involved in membrane trafficking, including Rab GTPases and SNARE proteins. **Clinical Significance:** The involvement of DENND2B in various cellular processes has significant implications for human health and disease. Alterations in DENND2B expression or function may contribute to: 1. **Cardiovascular diseases**: DENND2B's role in regulating cellular processes involved in cardiovascular function makes it a potential target for the treatment of cardiovascular diseases, such as hypertension and atherosclerosis. 2. **Cancer**: DENND2B's involvement in the regulation of cell growth and differentiation pathways may contribute to the development of cancer. Further research is needed to determine its role in cancer progression and treatment. 3. **Neurological disorders**: DENND2B's expression in ciliary muscle cells and anterior lens cells suggests its potential involvement in neurological disorders, such as glaucoma and cataracts. In conclusion, DENND2B is a gene with far-reaching implications in cellular processes, including guanyl-nucleotide exchange factor activity, Rab regulation of trafficking, and positive regulation of the ERK1/2 cascade. Its clinical significance is underscored by its involvement in cardiovascular diseases, cancer, and neurological disorders. Further research is needed to fully elucidate the functions of DENND2B and its potential applications in human health and disease.

Genular Protein ID: 1539996494

Symbol: DEN2B_HUMAN

Name: DENN domain-containing protein 2B

UniProtKB Accession Codes:

P78524 B2R6X7 B3KXQ6 P78523 Q16492 Q7KYY2 Q7KZ12 Q8NE12 Q9BQQ6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 5 ExpressionAtlas 1 GO 5 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 6 SMART 3 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8972856

Title: Differential expression of the human ST5 gene in HeLa-fibroblast hybrid cell lines mediated by YY1: evidence that YY1 plays a part in tumor suppression.

PubMed ID: 8972856

DOI: 10.1093/nar/24.23.4700

PubMed ID: 11528127

Title: Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7.

PubMed ID: 11528127

DOI: 10.1159/000056999

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1390339

Title: Identification of a human chromosome 11 gene which is differentially regulated in tumorigenic and nontumorigenic somatic cell hybrids of HeLa cells.

PubMed ID: 1390339

PubMed ID: 9632734

Title: Activation of extracellular signal-regulated kinase 2 by a novel Abl-binding protein, ST5.

PubMed ID: 9632734

DOI: 10.1074/jbc.273.26.16608

PubMed ID: 10229203

Title: Expression of an isoform of the novel signal transduction protein ST5 is linked to cell morphology.

PubMed ID: 10229203

DOI: 10.1038/sj.onc.1202554

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20937701

Title: Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

PubMed ID: 20937701

DOI: 10.1083/jcb.201008051

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29030480

Title: Intersectin-s interaction with DENND2B facilitates recycling of epidermal growth factor receptor.

PubMed ID: 29030480

DOI: 10.15252/embr.201744034

Sequence Information:

  • Length: 1137
  • Mass: 126485
  • Checksum: 96ACD16E0602479E
  • Sequence:
    • MTMTANKNSS ITHGAGGTKA PRGTLSRSQS VSPPPVLSPP RSPIYPLSDS ETSACRYPSH 
SSSRVLLKDR HPPAPSPQNP QDPSPDTSPP TCPFKTASFG YLDRSPSACK RDAQKESVQG 
AAQDVAGVAA CLPLAQSTPF PGPAAGPRGV LLTRTGTRAH SLGIREKISA WEGRREASPR 
MSMCGEKREG SGSEWAASEG CPSLGCPSVV PSPCSSEKTF DFKGLRRMSR TFSECSYPET 
EEEGEALPVR DSFYRLEKRL GRSEPSAFLR GHGSRKESSA VLSRIQKIEQ VLKEQPGRGL 
PQLPSSCYSV DRGKRKTGTL GSLEEPAGGA SVSAGSRAVG VAGVAGEAGP PPEREGSGST 
KPGTPGNSPS SQRLPSKSSL DPAVNPVPKP KRTFEYEADK NPKSKPSNGL PPSPTPAAPP 
PLPSTPAPPV TRRPKKDMRG HRKSQSRKSF EFEDASSLQS LYPSSPTENG TENQPKFGSK 
STLEENAYED IVGDLPKENP YEDVDLKSRR AGRKSQQLSE NSLDSLHRMW SPQDRKYNSP 
PTQLSLKPNS QSLRSGNWSE RKSHRLPRLP KRHSHDDMLL LAQLSLPSSP SSLNEDSLST 
TSELLSSRRA RRIPKLVQRI NSIYNAKRGK KRLKKLSMSS IETASLRDEN SESESDSDDR 
FKAHTQRLVH IQSMLKRAPS YRTLELELLE WQERELFEYF VVVSLKKKPS RNTYLPEVSY 
QFPKLDRPTK QMREAEERLK AIPQFCFPDA KDWLPVSEYS SETFSFMLTG EDGSRRFGYC 
RRLLPSGKGP RLPEVYCVIS RLGCFGLFSK VLDEVERRRG ISAALVYPFM RSLMESPFPA 
PGKTIKVKTF LPGAGNEVLE LRRPMDSRLE HVDFECLFTC LSVRQLIRIF ASLLLERRVI 
FVADKLSTLS SCSHAVVALL YPFSWQHTFI PVLPASMIDI VCCPTPFLVG LLSSSLPKLK 
ELPVEEALMV NLGSDRFIRQ MDDEDTLLPR KLQAALEQAL ERKNELISQD SDSDSDDECN 
TLNGLVSEVF IRFFVETVGH YSLFLTQSEK GERAFQREAF RKSVASKSIR RFLEVFMESQ 
MFAGFIQDRE LRKCRAKGLF EQRVEQYLEE LPDTEQSGMN KFLRGLGNKM KFLHKKN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.