Details for: STK10

Gene ID: 6793

Symbol: STK10

Ensembl ID: ENSG00000072786

Description: serine/threonine kinase 10

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 130.3158
    Cell Significance Index: -20.2700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 74.9477
    Cell Significance Index: -19.0100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 58.3621
    Cell Significance Index: -23.7100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 49.8459
    Cell Significance Index: -25.6400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.4134
    Cell Significance Index: -21.4700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.0309
    Cell Significance Index: -19.7700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.4360
    Cell Significance Index: -19.9200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.1041
    Cell Significance Index: -21.8200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.5955
    Cell Significance Index: -22.0800
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 3.0554
    Cell Significance Index: 8.1900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.0215
    Cell Significance Index: 37.3600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.6263
    Cell Significance Index: 23.3900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.5121
    Cell Significance Index: 44.4100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 1.2864
    Cell Significance Index: 22.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8309
    Cell Significance Index: 82.1900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.8227
    Cell Significance Index: 11.5400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7645
    Cell Significance Index: 690.2900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5519
    Cell Significance Index: 35.6100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4389
    Cell Significance Index: 16.6200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4312
    Cell Significance Index: 70.1300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4248
    Cell Significance Index: 46.2000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4056
    Cell Significance Index: 10.1400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3886
    Cell Significance Index: 77.9500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3539
    Cell Significance Index: 15.6600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.3161
    Cell Significance Index: 1.9100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2991
    Cell Significance Index: 17.9600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2953
    Cell Significance Index: 58.6100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2886
    Cell Significance Index: 34.0400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2442
    Cell Significance Index: 7.0400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2384
    Cell Significance Index: 18.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2082
    Cell Significance Index: 144.0300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1981
    Cell Significance Index: 13.7000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1705
    Cell Significance Index: 20.9600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1296
    Cell Significance Index: 23.3600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1020
    Cell Significance Index: 36.5900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0824
    Cell Significance Index: 15.6800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0624
    Cell Significance Index: 1.6700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0418
    Cell Significance Index: 64.2800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0237
    Cell Significance Index: 44.5400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0224
    Cell Significance Index: 41.4000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0191
    Cell Significance Index: 0.9000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0019
    Cell Significance Index: 0.0900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0056
    Cell Significance Index: -7.6600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0068
    Cell Significance Index: -3.7200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0128
    Cell Significance Index: -8.1400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0139
    Cell Significance Index: -0.3700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0259
    Cell Significance Index: -19.1500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0274
    Cell Significance Index: -1.8400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0276
    Cell Significance Index: -0.7400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0278
    Cell Significance Index: -4.0400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0286
    Cell Significance Index: -21.6800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0334
    Cell Significance Index: -24.4900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0334
    Cell Significance Index: -14.7600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0356
    Cell Significance Index: -16.1600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0387
    Cell Significance Index: -21.8100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0404
    Cell Significance Index: -25.2500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0564
    Cell Significance Index: -7.2300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0599
    Cell Significance Index: -3.1100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0703
    Cell Significance Index: -20.2200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0704
    Cell Significance Index: -0.9600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0798
    Cell Significance Index: -8.1500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0852
    Cell Significance Index: -11.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0876
    Cell Significance Index: -11.3200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0896
    Cell Significance Index: -15.3000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0906
    Cell Significance Index: -5.5700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0916
    Cell Significance Index: -10.6700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1092
    Cell Significance Index: -3.1300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1162
    Cell Significance Index: -24.4800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.1465
    Cell Significance Index: -0.9100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1537
    Cell Significance Index: -3.0000
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.1626
    Cell Significance Index: -2.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1641
    Cell Significance Index: -18.8000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1993
    Cell Significance Index: -20.7500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2069
    Cell Significance Index: -15.4200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2165
    Cell Significance Index: -4.6100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2188
    Cell Significance Index: -2.0200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2328
    Cell Significance Index: -4.8300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2351
    Cell Significance Index: -13.1900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2822
    Cell Significance Index: -14.7000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3006
    Cell Significance Index: -7.6800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3128
    Cell Significance Index: -19.1800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3157
    Cell Significance Index: -22.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3163
    Cell Significance Index: -10.1300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3218
    Cell Significance Index: -25.4900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3233
    Cell Significance Index: -4.6300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3571
    Cell Significance Index: -10.1900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3619
    Cell Significance Index: -22.8100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3745
    Cell Significance Index: -17.4600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3859
    Cell Significance Index: -20.2600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.4104
    Cell Significance Index: -11.4700
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.4165
    Cell Significance Index: -7.1800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4636
    Cell Significance Index: -16.2400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4653
    Cell Significance Index: -15.2400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.5055
    Cell Significance Index: -21.9800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5074
    Cell Significance Index: -16.1600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5103
    Cell Significance Index: -13.8900
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.5329
    Cell Significance Index: -5.6700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.5719
    Cell Significance Index: -20.1000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5869
    Cell Significance Index: -12.8500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.5878
    Cell Significance Index: -12.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** STK10 is a member of the LKB1 family of kinases, which are characterized by their ability to phosphorylate and activate downstream targets, including AMP-activated protein kinase (AMPK) and mechanistic target of rapamycin complex 1 (mTORC1). STK10 is a serine/threonine kinase with a specific substrate specificity, phosphorylating and activating a range of proteins involved in immune cell function. The kinase domain of STK10 is highly conserved across species, suggesting a conserved role in immune regulation. Additionally, STK10 has been implicated in the regulation of cell cycle progression, apoptosis, and autophagy, highlighting its role as a multifunctional kinase. **Pathways and Functions:** STK10 is involved in various signaling pathways that regulate immune cell function, including: 1. **Immune System Pathway:** STK10 regulates the function of immune cells, including T cells, monocytes, and natural killer cells, through the phosphorylation and activation of downstream targets. 2. **Cell Cycle Regulation:** STK10 modulates cell cycle progression by phosphorylating and activating proteins involved in cell cycle regulation, such as cyclin-dependent kinases (CDKs). 3. **Apoptosis and Autophagy:** STK10 regulates apoptosis and autophagy by phosphorylating and activating proteins involved in these processes, such as Bcl-2 family members and autophagy-related proteins. 4. **Signaling by Rho GTPases:** STK10 interacts with Rho GTPases, which are critical regulators of cell migration, cytoskeleton organization, and cell growth. **Clinical Significance:** Dysregulation of STK10 has been implicated in various diseases, including: 1. **Cancer:** STK10 mutations have been identified in several types of cancer, including colorectal, breast, and lung cancer, suggesting a role in tumorigenesis. 2. **Autoimmune Diseases:** STK10 has been implicated in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and lupus, where it regulates immune cell function and cytokine production. 3. **Infectious Diseases:** STK10 has been shown to regulate immune responses to viral infections, such as HIV and influenza, highlighting its role in controlling viral replication. 4. **Neurological Disorders:** STK10 has been implicated in the pathogenesis of neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it regulates neuronal function and survival. In conclusion, STK10 is a multifunctional kinase that plays a critical role in regulating immune cell function, cell cycle progression, apoptosis, and autophagy. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the mechanisms of STK10 and its clinical implications.

Genular Protein ID: 887690514

Symbol: STK10_HUMAN

Name: Serine/threonine-protein kinase 10

UniProtKB Accession Codes:

O94804 A6ND35 B2R8F5 B3KMY1 Q6NSK0 Q9UIW4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 1 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 3 EMBL 7 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 14 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 4 RefSeq 1 Rhea 6 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10199912

Title: Molecular cloning of the human gene STK10 encoding lymphocyte-oriented kinase, and comparative chromosomal mapping of the human, mouse, and rat homologues.

PubMed ID: 10199912

DOI: 10.1007/s002510050509

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11903060

Title: Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.

PubMed ID: 11903060

DOI: 10.1042/0264-6021:3630175

PubMed ID: 12639966

Title: Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue.

PubMed ID: 12639966

DOI: 10.1074/jbc.m212556200

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19255442

Title: LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.

PubMed ID: 19255442

DOI: 10.1073/pnas.0805963106

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21606217

Title: Off-target serine/threonine kinase 10 inhibition by erlotinib enhances lymphocytic activity leading to severe skin disorders.

PubMed ID: 21606217

DOI: 10.1124/mol.110.070862

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 18239682

Title: Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.

PubMed ID: 18239682

DOI: 10.1038/emboj.2008.8

PubMed ID: 16175573

Title: Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.

PubMed ID: 16175573

DOI: 10.1002/gcc.20265

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 968
  • Mass: 112135
  • Checksum: 15E245193ECC553D
  • Sequence:
    • MAFANFRRIL RLSTFEKRKS REYEHVRRDL DPNEVWEIVG ELGDGAFGKV YKAKNKETGA 
LAAAKVIETK SEEELEDYIV EIEILATCDH PYIVKLLGAY YHDGKLWIMI EFCPGGAVDA 
IMLELDRGLT EPQIQVVCRQ MLEALNFLHS KRIIHRDLKA GNVLMTLEGD IRLADFGVSA 
KNLKTLQKRD SFIGTPYWMA PEVVMCETMK DTPYDYKADI WSLGITLIEM AQIEPPHHEL 
NPMRVLLKIA KSDPPTLLTP SKWSVEFRDF LKIALDKNPE TRPSAAQLLE HPFVSSITSN 
KALRELVAEA KAEVMEEIED GRDEGEEEDA VDAASTLENH TQNSSEVSPP SLNADKPLEE 
SPSTPLAPSQ SQDSVNEPCS QPSGDRSLQT TSPPVVAPGN ENGLAVPVPL RKSRPVSMDA 
RIQVAQEKQV AEQGGDLSPA ANRSQKASQS RPNSSALETL GGEKLANGSL EPPAQAAPGP 
SKRDSDCSSL CTSESMDYGT NLSTDLSLNK EMGSLSIKDP KLYKKTLKRT RKFVVDGVEV 
SITTSKIISE DEKKDEEMRF LRRQELRELR LLQKEEHRNQ TQLSNKHELQ LEQMHKRFEQ 
EINAKKKFFD TELENLERQQ KQQVEKMEQD HAVRRREEAR RIRLEQDRDY TRFQEQLKLM 
KKEVKNEVEK LPRQQRKESM KQKMEEHTQK KQLLDRDFVA KQKEDLELAM KRLTTDNRRE 
ICDKERECLM KKQELLRDRE AALWEMEEHQ LQERHQLVKQ QLKDQYFLQR HELLRKHEKE 
REQMQRYNQR MIEQLKVRQQ QEKARLPKIQ RSEGKTRMAM YKKSLHINGG GSAAEQREKI 
KQFSQQEEKR QKSERLQQQQ KHENQMRDML AQCESNMSEL QQLQNEKCHL LVEHETQKLK 
ALDESHNQNL KEWRDKLRPR KKALEEDLNQ KKREQEMFFK LSEEAECPNP STPSKAAKFF 
PYSSADAS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.