Details for: TECTA
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 37.9954
Cell Significance Index: -5.9100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 23.3004
Cell Significance Index: -5.9100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 12.3075
Cell Significance Index: -5.0000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 5.2684
Cell Significance Index: -5.0300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 4.7690
Cell Significance Index: -5.8800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.0463
Cell Significance Index: -2.2900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.6340
Cell Significance Index: 9.0800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.5136
Cell Significance Index: 19.4500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.4788
Cell Significance Index: 15.3400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4565
Cell Significance Index: 20.1900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.4427
Cell Significance Index: 27.1400 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.3683
Cell Significance Index: 8.0700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2950
Cell Significance Index: 59.1700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2845
Cell Significance Index: 54.1400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2172
Cell Significance Index: 5.8200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2053
Cell Significance Index: 73.6500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1245
Cell Significance Index: 9.5600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0660
Cell Significance Index: 4.4400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0646
Cell Significance Index: 58.3300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0616
Cell Significance Index: 6.1000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0560
Cell Significance Index: 3.3600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.0550
Cell Significance Index: 1.5700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0521
Cell Significance Index: 3.2000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0422
Cell Significance Index: 4.6000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0332
Cell Significance Index: 4.8200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0310
Cell Significance Index: 5.0400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0274
Cell Significance Index: 1.5400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0234
Cell Significance Index: 0.5600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0160
Cell Significance Index: 0.4000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0107
Cell Significance Index: 2.1300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0035
Cell Significance Index: 0.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0016
Cell Significance Index: 3.0400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0008
Cell Significance Index: -1.4800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0010
Cell Significance Index: -1.3400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0016
Cell Significance Index: -2.4900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0017
Cell Significance Index: -0.0500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0024
Cell Significance Index: -1.5300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0026
Cell Significance Index: -0.0900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0034
Cell Significance Index: -0.2400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0056
Cell Significance Index: -4.1700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0060
Cell Significance Index: -2.7200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0070
Cell Significance Index: -5.1100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0075
Cell Significance Index: -5.6500 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0082
Cell Significance Index: -4.4700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0082
Cell Significance Index: -5.1200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0083
Cell Significance Index: -4.6800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0085
Cell Significance Index: -3.7700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0118
Cell Significance Index: -0.2600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0126
Cell Significance Index: -0.5700 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.0136
Cell Significance Index: -0.1500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0146
Cell Significance Index: -2.6400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0168
Cell Significance Index: -4.8200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0183
Cell Significance Index: -0.8000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0185
Cell Significance Index: -0.5900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0188
Cell Significance Index: -0.4000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0228
Cell Significance Index: -3.8900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0239
Cell Significance Index: -3.0700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0255
Cell Significance Index: -5.3700 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.0262
Cell Significance Index: -0.3800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0263
Cell Significance Index: -0.5200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0291
Cell Significance Index: -2.9700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0301
Cell Significance Index: -4.1300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0337
Cell Significance Index: -3.8600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0366
Cell Significance Index: -4.5000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0398
Cell Significance Index: -2.5100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0420
Cell Significance Index: -4.8900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0420
Cell Significance Index: -1.0800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0430
Cell Significance Index: -5.5600 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0445
Cell Significance Index: -0.6700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0446
Cell Significance Index: -2.0800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0478
Cell Significance Index: -5.6400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0535
Cell Significance Index: -1.7500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0546
Cell Significance Index: -5.6800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0568
Cell Significance Index: -2.9500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0682
Cell Significance Index: -5.4000 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0732
Cell Significance Index: -1.4700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0735
Cell Significance Index: -3.8300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0742
Cell Significance Index: -5.5300 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0824
Cell Significance Index: -1.7800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0834
Cell Significance Index: -2.3300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0836
Cell Significance Index: -1.0400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0838
Cell Significance Index: -2.0900 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.0851
Cell Significance Index: -1.3500 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0864
Cell Significance Index: -1.2300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0890
Cell Significance Index: -5.7500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.0890
Cell Significance Index: -1.1100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0909
Cell Significance Index: -4.7700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0918
Cell Significance Index: -3.2200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0934
Cell Significance Index: -1.9900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0992
Cell Significance Index: -4.6600 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.1016
Cell Significance Index: -1.3700 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1091
Cell Significance Index: -2.1300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1097
Cell Significance Index: -1.6200 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.1101
Cell Significance Index: -1.2000 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.1133
Cell Significance Index: -1.4300 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1173
Cell Significance Index: -3.7100 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.1184
Cell Significance Index: -1.5800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.1324
Cell Significance Index: -3.2300 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.1363
Cell Significance Index: -1.1300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1400
Cell Significance Index: -5.1400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1572298959
Symbol: TECTA_HUMAN
Name: Alpha-tectorin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9590290
Title: Mutations in the human alpha-tectorin gene cause autosomal dominant non-syndromic hearing impairment.
PubMed ID: 9590290
DOI: 10.1038/ng0598-60
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 21368133
Title: Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4).
PubMed ID: 21368133
PubMed ID: 10196713
Title: Mutation in the zonadhesin-like domain of alpha-tectorin associated with autosomal dominant non-syndromic hearing loss.
PubMed ID: 10196713
PubMed ID: 10987647
Title: Alpha-tectorin involvement in hearing disabilities: one gene -- two phenotypes.
PubMed ID: 10987647
PubMed ID: 9949200
Title: An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.
PubMed ID: 9949200
DOI: 10.1093/hmg/8.3.409
PubMed ID: 11333869
Title: A cysteine substitution in the zona pellucida domain of alpha-tectorin results in autosomal dominant, postlingual, progressive, mid frequency hearing loss in a Spanish family.
PubMed ID: 11333869
DOI: 10.1136/jmg.38.5.e13
PubMed ID: 12162770
Title: Association of clinical features with mutation of TECTA in a family with autosomal dominant hearing loss.
PubMed ID: 12162770
PubMed ID: 12746400
Title: Distinctive audiometric profile associated with DFNB21 alleles of TECTA.
PubMed ID: 12746400
DOI: 10.1136/jmg.40.5.360
PubMed ID: 15319541
Title: A genotype-phenotype correlation with gender-effect for hearing impairment caused by TECTA mutations.
PubMed ID: 15319541
DOI: 10.1159/000080347
PubMed ID: 16718611
Title: A novel TECTA mutation in a Dutch DFNA8/12 family confirms genotype-phenotype correlation.
PubMed ID: 16718611
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 17661817
Title: Audioprofiling identifies TECTA and GJB2-related deafness segregating in a single extended pedigree.
PubMed ID: 17661817
PubMed ID: 20947814
Title: Two novel missense mutations in the TECTA gene in Korean families with autosomal dominant nonsyndromic hearing loss.
PubMed ID: 20947814
PubMed ID: 21520338
Title: DFNA8/12 caused by TECTA mutations is the most identified subtype of nonsyndromic autosomal dominant hearing loss.
PubMed ID: 21520338
DOI: 10.1002/humu.21512
Sequence Information:
- Length: 2155
- Mass: 239527
- Checksum: A7CB1CD9E7C594C3
- Sequence:
MNYSSFLRIW VSFIFALVQH QAQPRELMYP FWQNDTKTPK VDDGSSSEIK LAIPVFFFGV PYRTVYVNNN GVVSFNVLVS QFTPESFPLT DGRAFVAPFW ADVHNGIRGE IYYRETMEPA ILKRATKDIR KYFKDMATFS ATWVFIVTWE EVTFYGGSST TPVNTFQAVL VSDGSYTFTL FNYYEINWTT GTASGGDPLT GLGGVMAQAG FNGGNLTNFF SLPGSRTPEI VNIQETTNVN VPGRWAFKVD GKEIDPANGC TSRGQFLRRG EVFWDDLNCT VKCRCLDFNN EIYCQEASCS PYEVCEPKGK FFYCSAVETS TCVVFGEPHY HTFDGFLFHF QGSCAYLLAR QCLQTSSLPF FSVEAKNEHR RGSAVSWVKE LSVEVNGYKI LIPKGSYGRV KVNDLVTSLP VTLDLGTVKI YQSGISTAVE TDFGLLVTFD GQHYASISVP GSYINSTCGL CGNYNKNPLD DFLRPDGRPA MSVLDLGESW RVYHADWKCD SGCVDNCTQC DAATEALYFG SDYCGFLNKT DGPLWECGTV VDPTAFVHSC VYDLCSVRDN GTLLCQAIQA YALVCQALGI PIGDWRTQTG CVSTVQCPSF SHYSVCTSSC PDTCSDLTAS RNCATPCTEG CECNQGFVLS TSQCVPLHKC GCDFDGHYYT MGEFFWATAN CTVQCLCEEG GDVYCFNKTC GSGEVCAVED GYQGCFPKRE TVCLLSQNQV LHTFDGASYA FPSEFSYTLL KTCPERPEYL EIDINKKKPD AGPAWLRGLR ILVADQEVKI GGIGASEVKL NGQEVELPFF HPSGKLEIYR NKNSTTVESK GVVTVQYSDI GLLYIRLSTT YFNCTGGLCG FYNANASDEF CLPNGKCTDN LAVFLESWTT FEEICNGECG DLLKACNNDS ELLKFYRSRS RCGIINDPSN SSFLECHGVV NVTAYYRTCL FRLCQSGGNE SELCDSVARY ASACKNADVE VGPWRTYDFC PLECPENSHF EECITCTETC ETLTLGPICV DSCSEGCQCD EGYALLGSQC VTRSECGCNF EGHQLATNET FWVDLDCQIF CYCSGTDNRV HCETIPCKDD EYCMEEGGLY YCQARTDASC IVSGYGHYLT FDGFPFDFQT SCPLILCTTG SRPSSDSFPK FVVTAKNEDR DPSLALWVKQ VDVTVFGYSI VIHRAYKHTV LVNSERLYLP LKLGQGKINI FSFGFHVVVE TDFGLKVVYD WKTFLSITVP RSMQNSTYGL CGRYNGNPDD DLEMPMGLLA SSVNEFGQSW VKRDTFCQVG CGDRCPSCAK VEGFSKVQQL CSLIPNQNAA FSKCHSKVNP TFFYKNCLFD SCIDGGAVQT ACSWLQNYAS TCQTQGITVT GWRNYTSCTV TCPPNSHYES CVSVCQPRCA AIRLKSDCSH YCVEGCHCDA GYVLNGKSCI LPHSCGCYSD GKYYEPKQLF WNSDCTRRCR CFRRNVIQCD PRQCKSDEEC ALRNGVRGCF STKTSYCLAA GGGVFRTFDG AFLRFPANCA FVLSTICQKL PDISFQLIIN FDKWSAPNLT IISPVYFYIN EEQILINDRN TVKVNGTQVN VPFITGLATK IYSSEGFLVI DTSPDIQIYY NGFNVIKISI SERLQNKVCG LCGNFNGDLT DDYVTLRGKP VVSSVVLAQS WKTNGMQKRP LAPSCNELQF SQYAAMCDNV HIQKMQGDGY CLKLTDMKGF FQPCYGLLDP LPFYESCYLD GCYSHKKFQL CGSLAAYGEA CRSFGILSTE WIEKENCSGV VEDPCVGADC PNRTCELGNG RELCGCIEPP PYGNNSHDII DAEVTCKAAQ MEVSISKCKL FQLGFEREGV RINDRQCTGI EGEDFISFQI NNTKGNCGNI VQSNGTHIMY KNTLWIESAN NTGNIITRDR TINVEFSCAY ELDIKISLDS VVKPMLSVIN LTVPTQEGSF ITKMALYKNA SYKHPYRQGE VVLTTRDVLY VGVFVVGADA THLILTLNKC YATPTRDSND KLRYFIIEGG CQNLKDNTIG IEENAVSLTC RFHVTVFKFI GDYDEVHLHC AVSLCDSEKY SCKITCPHNS RIATDYTKEP KEQIISVGPI RRKRLDWCED NGGCEQICTS RVDGPLCSCV TGTLQEDGKS CRASNSSMEL QVWTLLLIMI QISLWHFVYK SGTTS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.