Details for: NR2C2

Gene ID: 7182

Symbol: NR2C2

Ensembl ID: ENSG00000177463

Description: nuclear receptor subfamily 2 group C member 2

Associated with

  • Gene expression (transcription)
    (R-HSA-74160)
  • Generic transcription pathway
    (R-HSA-212436)
  • Nuclear receptor transcription pathway
    (R-HSA-383280)
  • Rna polymerase ii transcription
    (R-HSA-73857)
  • Cell differentiation
    (GO:0030154)
  • Chromatin
    (GO:0000785)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Intracellular receptor signaling pathway
    (GO:0030522)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nervous system development
    (GO:0007399)
  • Nuclear receptor activity
    (GO:0004879)
  • Nucleoplasm
    (GO:0005654)
  • Positive regulation of embryonic development
    (GO:0040019)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Spermatogenesis
    (GO:0007283)
  • Zinc ion binding
    (GO:0008270)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 213.6999
    Cell Significance Index: -33.2400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 132.2723
    Cell Significance Index: -33.5500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 73.9215
    Cell Significance Index: -34.9000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 69.9557
    Cell Significance Index: -28.4200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 63.8821
    Cell Significance Index: -32.8600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 29.9033
    Cell Significance Index: -28.5500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.8842
    Cell Significance Index: -34.3800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.4381
    Cell Significance Index: -33.3200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.4040
    Cell Significance Index: -22.7700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.7429
    Cell Significance Index: -34.5000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.8175
    Cell Significance Index: 101.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4289
    Cell Significance Index: 286.6400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3944
    Cell Significance Index: 276.7200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.3659
    Cell Significance Index: 35.1100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.0703
    Cell Significance Index: 29.9100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.0699
    Cell Significance Index: 124.6900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9906
    Cell Significance Index: 355.3000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9788
    Cell Significance Index: 75.1100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8878
    Cell Significance Index: 54.5700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.8394
    Cell Significance Index: 20.1300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7857
    Cell Significance Index: 127.7900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7326
    Cell Significance Index: 79.6900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6728
    Cell Significance Index: 9.1800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.5942
    Cell Significance Index: 11.6000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.5646
    Cell Significance Index: 8.1200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5314
    Cell Significance Index: 31.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4874
    Cell Significance Index: 87.8700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4503
    Cell Significance Index: 311.4200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.4352
    Cell Significance Index: 9.5300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4159
    Cell Significance Index: 375.5300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.4077
    Cell Significance Index: 8.7100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4031
    Cell Significance Index: 17.8300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3905
    Cell Significance Index: 11.2500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3816
    Cell Significance Index: 6.5400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3576
    Cell Significance Index: 13.5400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.3544
    Cell Significance Index: 9.5000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3517
    Cell Significance Index: 15.9400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3409
    Cell Significance Index: 64.8700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3380
    Cell Significance Index: 22.7300
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.3323
    Cell Significance Index: 2.9500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2596
    Cell Significance Index: 31.9200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1952
    Cell Significance Index: 4.8800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1897
    Cell Significance Index: 4.1100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1642
    Cell Significance Index: 16.2400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1437
    Cell Significance Index: 270.5600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1296
    Cell Significance Index: 57.3200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1134
    Cell Significance Index: 174.6500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1008
    Cell Significance Index: 185.9700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0908
    Cell Significance Index: 49.5800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0906
    Cell Significance Index: 57.5700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0842
    Cell Significance Index: 5.8200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0780
    Cell Significance Index: 35.4200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.0730
    Cell Significance Index: 1.7800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0568
    Cell Significance Index: 77.2400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0323
    Cell Significance Index: 1.6800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0275
    Cell Significance Index: 3.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0011
    Cell Significance Index: 0.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0194
    Cell Significance Index: -2.8200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0233
    Cell Significance Index: -1.4700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0309
    Cell Significance Index: -22.9100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0310
    Cell Significance Index: -2.0000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0312
    Cell Significance Index: -22.9100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0414
    Cell Significance Index: -31.3300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0496
    Cell Significance Index: -27.9500
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0557
    Cell Significance Index: -0.8000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0630
    Cell Significance Index: -39.3700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0631
    Cell Significance Index: -8.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0700
    Cell Significance Index: -11.9500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0824
    Cell Significance Index: -9.7200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0857
    Cell Significance Index: -4.0300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0885
    Cell Significance Index: -0.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0988
    Cell Significance Index: -5.1300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0992
    Cell Significance Index: -28.5400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1068
    Cell Significance Index: -4.9800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1453
    Cell Significance Index: -16.6500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1662
    Cell Significance Index: -3.5400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1762
    Cell Significance Index: -37.1200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1793
    Cell Significance Index: -23.1600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1815
    Cell Significance Index: -18.5400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2139
    Cell Significance Index: -22.2700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2428
    Cell Significance Index: -6.6100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2598
    Cell Significance Index: -3.8400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2901
    Cell Significance Index: -21.6200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2931
    Cell Significance Index: -10.3000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3038
    Cell Significance Index: -8.6700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3080
    Cell Significance Index: -6.3900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3140
    Cell Significance Index: -22.2100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3768
    Cell Significance Index: -29.8400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4531
    Cell Significance Index: -27.7800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4663
    Cell Significance Index: -24.4800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4991
    Cell Significance Index: -5.9500
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.5063
    Cell Significance Index: -8.1700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5119
    Cell Significance Index: -16.7600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5195
    Cell Significance Index: -16.5500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5541
    Cell Significance Index: -11.7600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5683
    Cell Significance Index: -16.2900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5791
    Cell Significance Index: -11.4500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.5873
    Cell Significance Index: -8.8500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6185
    Cell Significance Index: -19.8100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.6326
    Cell Significance Index: -9.0600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transcription Factor:** NR2C2 is a nuclear receptor that functions as a transcription factor, regulating the expression of target genes by binding to specific DNA sequences. 2. **Zinc-Binding:** The NR2C2 protein contains a zinc-binding domain, which is essential for its DNA-binding activity. 3. **RNA Polymerase II-Dependent:** NR2C2 exhibits RNA polymerase II-dependent transcriptional activity, indicating its involvement in the regulation of gene expression by this enzyme. 4. **Developmental Expression:** The NR2C2 gene is highly expressed in cells involved in embryonic development, suggesting its critical role in the regulation of developmental processes. **Pathways and Functions:** 1. **Chromatin Remodeling:** NR2C2 regulates chromatin structure and dynamics, influencing gene expression and cellular differentiation. 2. **Transcriptional Regulation:** The NR2C2 protein binds to specific DNA sequences, recruiting RNA polymerase II and other transcriptional machinery components to activate or repress gene expression. 3. **Embryonic Development:** NR2C2 is essential for the regulation of embryonic development, including nervous system formation and tissue patterning. 4. **Cell Differentiation:** The NR2C2 gene is involved in the regulation of cellular differentiation, influencing the development of various cell types, including neurons, muscle fibers, and epithelial cells. **Clinical Significance:** 1. **Neurological Disorders:** Aberrant NR2C2 expression has been linked to various neurological disorders, including autism spectrum disorder, schizophrenia, and peripheral neuropathy. 2. **Cancer:** NR2C2 may play a role in cancer development and progression, particularly in tissues with high NR2C2 expression, such as the nervous system and muscle. 3. **Muscular Dystrophy:** Mutations in the NR2C2 gene have been associated with muscular dystrophy, highlighting its critical role in muscle development and function. 4. **Therapeutic Targeting:** Understanding the NR2C2 gene's function and regulation may lead to the development of novel therapeutic strategies for the treatment of diseases associated with NR2C2 dysfunction. In conclusion, the NR2C2 gene is a critical regulator of gene expression and development in various tissues, including the nervous system, muscle, and other organs. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the NR2C2 gene's function and potential therapeutic applications.

Genular Protein ID: 1128722

Symbol: NR2C2_HUMAN

Name: Nuclear receptor subfamily 2 group C member 2

UniProtKB Accession Codes:

P49116 A8K3H5 B6ZGT8 P55092

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EMBL 7 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 2 PRINTS 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7708055

Title: TAK1: molecular cloning and characterization of a new member of the nuclear receptor superfamily.

PubMed ID: 7708055

DOI: 10.1210/mend.8.12.7708055

PubMed ID: 8016112

Title: Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily.

PubMed ID: 8016112

DOI: 10.1073/pnas.91.13.6040

PubMed ID: 18619963

Title: DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system.

PubMed ID: 18619963

DOI: 10.1016/j.febslet.2008.07.003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 7779113

Title: The orphan receptor TAK1 acts as a repressor of RAR-, RXR- and T3R-mediated signaling pathways.

PubMed ID: 7779113

DOI: 10.1006/bbrc.1995.1781

PubMed ID: 9556573

Title: Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4.

PubMed ID: 9556573

DOI: 10.1074/jbc.273.18.10948

PubMed ID: 10347174

Title: Differential regulation of direct repeat 3 vitamin D3 and direct repeat 4 thyroid hormone signaling pathways by the human TR4 orphan receptor.

PubMed ID: 10347174

DOI: 10.1074/jbc.274.23.16198

PubMed ID: 10644740

Title: Nuclear orphan receptors regulate transcription of the gene for the human luteinizing hormone receptor.

PubMed ID: 10644740

DOI: 10.1074/jbc.275.4.2763

PubMed ID: 12486131

Title: Identification of a novel testicular orphan receptor-4 (TR4)-associated protein as repressor for the selective suppression of TR4-mediated transactivation.

PubMed ID: 12486131

DOI: 10.1074/jbc.m207116200

PubMed ID: 15302918

Title: TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4.

PubMed ID: 15302918

DOI: 10.1093/nar/gkh741

PubMed ID: 17974920

Title: The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.

PubMed ID: 17974920

DOI: 10.1101/gad.1593307

PubMed ID: 18388194

Title: Oxidative stress stimulates testicular orphan receptor 4 through forkhead transcription factor forkhead box O3a.

PubMed ID: 18388194

DOI: 10.1210/en.2008-0121

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22672233

Title: NLRP10 enhances Shigella-induced pro-inflammatory responses.

PubMed ID: 22672233

DOI: 10.1111/j.1462-5822.2012.01822.x

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 596
  • Mass: 65414
  • Checksum: 5180BDC3F3C8BD79
  • Sequence:
    • MTSPSPRIQI ISTDSAVASP QRIQIVTDQQ TGQKIQIVTA VDASGSPKQQ FILTSPDGAG 
TGKVILASPE TSSAKQLIFT TSDNLVPGRI QIVTDSASVE RLLGKTDVQR PQVVEYCVVC 
GDKASGRHYG AVSCEGCKGF FKRSVRKNLT YSCRSNQDCI INKHHRNRCQ FCRLKKCLEM 
GMKMESVQSE RKPFDVQREK PSNCAASTEK IYIRKDLRSP LIATPTFVAD KDGARQTGLL 
DPGMLVNIQQ PLIREDGTVL LATDSKAETS QGALGTLANV VTSLANLSES LNNGDTSEIQ 
PEDQSASEIT RAFDTLAKAL NTTDSSSSPS LADGIDTSGG GSIHVISRDQ STPIIEVEGP 
LLSDTHVTFK LTMPSPMPEY LNVHYICESA SRLLFLSMHW ARSIPAFQAL GQDCNTSLVR 
ACWNELFTLG LAQCAQVMSL STILAAIVNH LQNSIQEDKL SGDRIKQVME HIWKLQEFCN 
SMAKLDIDGY EYAYLKAIVL FSPDHPGLTS TSQIEKFQEK AQMELQDYVQ KTYSEDTYRL 
ARILVRLPAL RLMSSNITEE LFFTGLIGNV SIDSIIPYIL KMETAEYNGQ ITGASL

Genular Protein ID: 2333197194

Symbol: F2YGU2_HUMAN

Name: N/A

UniProtKB Accession Codes:

F2YGU2 A0A024R2N9

Database IDs:

ARBA 10 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 7 Gene3D 2 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 5 Pfam 2 RefSeq 4 RuleBase 1 SMART 2 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 615
  • Mass: 67345
  • Checksum: 5D557E04602C1BAB
  • Sequence:
    • MTSPSPRIQI ISTDSAVASP QRIQGSEPAS GPLSVFTSLN KEKIVTDQQT GQKIQIVTAV 
DASGSPKQQF ILTSPDGAGT GKVILASPET SSAKQLIFTT SDNLVPGRIQ IVTDSASVER 
LLGKTDVQRP QVVEYCVVCG DKASGRHYGA VSCEGCKGFF KRSVRKNLTY SCRSNQDCII 
NKHHRNRCQF CRLKKCLEMG MKMESVQSER KPFDVQREKP SNCAASTEKI YIRKDLRSPL 
IATPTFVADK DGARQTGLLD PGMLVNIQQP LIREDGTVLL ATDSKAETSQ GALGTLANVV 
TSLANLSESL NNGDTSEIQP EDQSASEITR AFDTLAKALN TTDSSSSPSL ADGIDTSGGG 
SIHVISRDQS TPIIEVEGPL LSDTHVTFKL TMPSPMPEYL NVHYICESAS RLLFLSMHWA 
RSIPAFQALG QDCNTSLVRA CWNELFTLGL AQCAQVMSLS TILAAIVNHL QNSIQEDKLS 
GDRIKQVMEH IWKLQEFCNS MAKLDIDGYE YAYLKAIVLF SPDHPGLTST SQIEKFQEKA 
QMELQDYVQK TYSEDTYRLA RILVRLPALR LMSSNITEEL FFTGLIGNVS IDSIIPYILK 
METAEYNGQI TGASL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.