Details for: TULP1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 10.8474
Cell Significance Index: 683.6800 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 10.4542
Cell Significance Index: 146.8300 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 2.0990
Cell Significance Index: 18.4900 - Cell Name: bipolar neuron (CL0000103)
Fold Change: 1.0826
Cell Significance Index: 6.0700 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 1.0586
Cell Significance Index: 13.2200 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.9366
Cell Significance Index: 11.8500 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.5057
Cell Significance Index: 6.1300 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.4816
Cell Significance Index: 7.6400 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 0.3524
Cell Significance Index: 2.1800 - Cell Name: Mueller cell (CL0000636)
Fold Change: 0.2353
Cell Significance Index: 1.8100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.2077
Cell Significance Index: 2.9800 - Cell Name: diffuse bipolar 2 cell (CL4033028)
Fold Change: 0.1791
Cell Significance Index: 2.2000 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1782
Cell Significance Index: 3.7300 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.1778
Cell Significance Index: 2.1200 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0.1531
Cell Significance Index: 1.7300 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.1300
Cell Significance Index: 3.1500 - Cell Name: myometrial cell (CL0002366)
Fold Change: 0.1268
Cell Significance Index: 1.4600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0623
Cell Significance Index: 7.9900 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.0594
Cell Significance Index: 0.4900 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.0182
Cell Significance Index: 0.1400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0171
Cell Significance Index: 0.9600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0131
Cell Significance Index: 0.2200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0104
Cell Significance Index: 19.5300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0076
Cell Significance Index: 0.4000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0036
Cell Significance Index: 0.6400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0027
Cell Significance Index: 1.8700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0012
Cell Significance Index: 0.1800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0003
Cell Significance Index: -0.6100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0003
Cell Significance Index: -0.4900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0006
Cell Significance Index: -0.7800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0013
Cell Significance Index: -0.8500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0015
Cell Significance Index: -0.6800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0019
Cell Significance Index: -0.3700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0029
Cell Significance Index: -0.5900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0029
Cell Significance Index: -1.0300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0030
Cell Significance Index: -0.8600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0033
Cell Significance Index: -2.4500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0033
Cell Significance Index: -2.5100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0038
Cell Significance Index: -2.0700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0040
Cell Significance Index: -0.4900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0040
Cell Significance Index: -2.2400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0054
Cell Significance Index: -0.1400 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.0064
Cell Significance Index: -0.0400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0071
Cell Significance Index: -0.2000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0079
Cell Significance Index: -1.3500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0090
Cell Significance Index: -1.2400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0128
Cell Significance Index: -1.4900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0131
Cell Significance Index: -0.6800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0159
Cell Significance Index: -0.7400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0182
Cell Significance Index: -2.0900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0184
Cell Significance Index: -2.3800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0204
Cell Significance Index: -0.5500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0212
Cell Significance Index: -0.7800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0215
Cell Significance Index: -1.0900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0220
Cell Significance Index: -0.6000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0224
Cell Significance Index: -2.2900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0224
Cell Significance Index: -2.3300 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.0230
Cell Significance Index: -0.3300 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: -0.0266
Cell Significance Index: -0.3100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0283
Cell Significance Index: -1.7400 - Cell Name: flat midget bipolar cell (CL4033033)
Fold Change: -0.0290
Cell Significance Index: -0.3600 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.0293
Cell Significance Index: -0.3700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0308
Cell Significance Index: -2.0700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0312
Cell Significance Index: -1.4700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0319
Cell Significance Index: -2.4500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0327
Cell Significance Index: -2.4400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0333
Cell Significance Index: -0.9600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0337
Cell Significance Index: -0.4600 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0339
Cell Significance Index: -0.4200 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: -0.0364
Cell Significance Index: -0.3600 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0372
Cell Significance Index: -1.5200 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0380
Cell Significance Index: -0.4200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0407
Cell Significance Index: -1.7700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0409
Cell Significance Index: -2.1300 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: -0.0431
Cell Significance Index: -0.5200 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: -0.0431
Cell Significance Index: -0.5900 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.0432
Cell Significance Index: -0.8500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0453
Cell Significance Index: -2.0100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0464
Cell Significance Index: -1.6300 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0464
Cell Significance Index: -0.6600 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: -0.0474
Cell Significance Index: -0.6000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0484
Cell Significance Index: -2.2000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0502
Cell Significance Index: -0.8600 - Cell Name: diffuse bipolar 3b cell (CL4033030)
Fold Change: -0.0531
Cell Significance Index: -0.6400 - Cell Name: retinal astrocyte (CL4033015)
Fold Change: -0.0531
Cell Significance Index: -0.5200 - Cell Name: amacrine cell (CL0000561)
Fold Change: -0.0535
Cell Significance Index: -0.6700 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.0556
Cell Significance Index: -0.9500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0576
Cell Significance Index: -2.1800 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: -0.0577
Cell Significance Index: -0.6300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0582
Cell Significance Index: -2.0400 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0602
Cell Significance Index: -1.4700 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0617
Cell Significance Index: -1.2600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0618
Cell Significance Index: -1.8200 - Cell Name: S cone cell (CL0003050)
Fold Change: -0.0618
Cell Significance Index: -0.7200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0619
Cell Significance Index: -2.1500 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0630
Cell Significance Index: -1.5700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0638
Cell Significance Index: -2.0900 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0641
Cell Significance Index: -1.6000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0645
Cell Significance Index: -1.8400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0656
Cell Significance Index: -1.3600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2687787125
Symbol: TULP1_HUMAN
Name: Tubby-related protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9096357
Title: Molecular characterization of TUB, TULP1, and TULP2, members of the novel tubby gene family and their possible relation to ocular diseases.
PubMed ID: 9096357
PubMed ID: 9462751
Title: TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa.
PubMed ID: 9462751
DOI: 10.1038/ng0298-177
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16303976
Title: Tubby-like protein 1 (TULP1) interacts with F-actin in photoreceptor cells.
PubMed ID: 16303976
DOI: 10.1167/iovs.05-0693
PubMed ID: 19837063
Title: Identification of tubby and tubby-like protein 1 as eat-me signals by phage display.
PubMed ID: 19837063
PubMed ID: 9660588
Title: Tubby-like protein-1 mutations in autosomal recessive retinitis pigmentosa.
PubMed ID: 9660588
PubMed ID: 9462750
Title: Recessive mutations in the gene encoding the tubby-like protein TULP1 in patients with retinitis pigmentosa.
PubMed ID: 9462750
DOI: 10.1038/ng0298-174
PubMed ID: 15024725
Title: Leber congenital amaurosis: comprehensive survey of the genetic heterogeneity, refinement of the clinical definition, and genotype-phenotype correlations as a strategy for molecular diagnosis.
PubMed ID: 15024725
DOI: 10.1002/humu.20010
PubMed ID: 15557452
Title: A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa, using microsatellite markers.
PubMed ID: 15557452
DOI: 10.1167/iovs.04-0544
PubMed ID: 17620573
Title: Novel compound heterozygous TULP1 mutations in a family with severe early-onset retinitis pigmentosa.
PubMed ID: 17620573
PubMed ID: 17962469
Title: Novel TULP1 mutation causing Leber congenital amaurosis or early onset retinal degeneration.
PubMed ID: 17962469
DOI: 10.1167/iovs.06-1013
Sequence Information:
- Length: 542
- Mass: 60609
- Checksum: 65320103E2674B60
- Sequence:
MPLRDETLRE VWASDSGHEE ESLSPEAPRR PKQRPAPAQR LRKKRTEAPE SPCPTGSKPR KPGAGRTGRP REEPSPDPAQ ARAPQTVYAR FLRDPEAKKR DPRETFLVAR APDAEDEEEE EEEDEEDEEE EAEEKKEKIL LPPKKPLREK SSADLKERRA KAQGPRGDLG SPDPPPKPLR VRNKEAPAGE GTKMRKTKKK GSGEADKDPS GSPASARKSP AAMFLVGEGS PDKKALKKKG TPKGARKEEE EEEEAATVIK KSNQKGKAKG KGKKKAKEER APSPPVEVDE PREFVLRPAP QGRTVRCRLT RDKKGMDRGM YPSYFLHLDT EKKVFLLAGR KRKRSKTANY LISIDPTNLS RGGENFIGKL RSNLLGNRFT VFDNGQNPQR GYSTNVASLR QELAAVIYET NVLGFRGPRR MTVIIPGMSA ENERVPIRPR NASDGLLVRW QNKTLESLIE LHNKPPVWND DSGSYTLNFQ GRVTQASVKN FQIVHADDPD YIVLQFGRVA EDAFTLDYRY PLCALQAFAI ALSSFDGKLA CE
Genular Protein ID: 342579956
Symbol: F1T0I9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 21697133
Title: Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.
PubMed ID: 21697133
DOI: 10.1167/iovs.11-7479
Sequence Information:
- Length: 441
- Mass: 48934
- Checksum: A38C3D5EE0481425
- Sequence:
MPLRDETLRE VWASDSGHEE ESLSPEAPRR PKQRPAPAQR LRKKRTEAPE SPCPTGSKPR KPGAGRRGRP REEPSPDPAQ ARAPQTVYAR FLRDPEAKKR DPRETFLVAR APDAEDEEEE EEEDEEDEEE EAEEKKEKIL LPPKKPLREK SSADLKERRA KAQGPRGDLG SPDPPPKPLR VRNKEAPAGE GTKMRKTKKK GSGEADKDPS GSPASARKSP AAMFLVGEGS PDKKALKKKG TPKGARKEEE EEEEAATVIK NSNQKGKAKG KGKKKAEERA PSPPVEVDEP REFVLRPAPQ GRTVRCRLTR DKKGMDRGMY PSYFLHLDTE KKVFLLAGRK RKRSKTANYL ISIDPTNLSR GGENFIGKLR WGWASWGWGD LGQQKAIARH LCPAVPGRAP TTVGTLETSP SLGPLALMYI DHVGSLLKWL SVWGGPGSLH F
Genular Protein ID: 3392040761
Symbol: Q0QD38_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 17286855
Title: Mapping of transcription start sites of human retina expressed genes.
PubMed ID: 17286855
Sequence Information:
- Length: 20
- Mass: 2358
- Checksum: C4F02BEB10B6E4F8
- Sequence:
MPLRDETLRE VWASDSGHEE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.