Details for: WEE1

Gene ID: 7465

Symbol: WEE1

Ensembl ID: ENSG00000166483

Description: WEE1 G2 checkpoint kinase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 146.4204
    Cell Significance Index: -22.7800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 100.2983
    Cell Significance Index: -25.4400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 66.9988
    Cell Significance Index: -27.6000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 57.6121
    Cell Significance Index: -27.2000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 52.6514
    Cell Significance Index: -21.3900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 40.6544
    Cell Significance Index: -27.2800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.2092
    Cell Significance Index: -26.1500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.8923
    Cell Significance Index: -26.5000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 7.5509
    Cell Significance Index: 46.4700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.8144
    Cell Significance Index: -26.8900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 6.5954
    Cell Significance Index: 89.9900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 4.3077
    Cell Significance Index: 223.7700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.2651
    Cell Significance Index: -13.1000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.8649
    Cell Significance Index: 105.2000
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 3.3826
    Cell Significance Index: 10.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.4731
    Cell Significance Index: 184.3200
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 2.4440
    Cell Significance Index: 5.5100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.1849
    Cell Significance Index: 58.3400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.1293
    Cell Significance Index: 61.3500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.0939
    Cell Significance Index: 94.9100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.6892
    Cell Significance Index: 274.7300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.5500
    Cell Significance Index: 35.8100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.4034
    Cell Significance Index: 181.3100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.3101
    Cell Significance Index: 18.6500
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.2462
    Cell Significance Index: 13.0100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.2102
    Cell Significance Index: 34.6900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1137
    Cell Significance Index: 1005.6300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0667
    Cell Significance Index: 131.1700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.0251
    Cell Significance Index: 184.8000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.0153
    Cell Significance Index: 9.3500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.9997
    Cell Significance Index: 14.9800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9922
    Cell Significance Index: 107.9200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.9468
    Cell Significance Index: 44.5000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8932
    Cell Significance Index: 53.6200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.8207
    Cell Significance Index: 52.9500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8069
    Cell Significance Index: 160.1400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7116
    Cell Significance Index: 50.3300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6864
    Cell Significance Index: 303.4800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.6637
    Cell Significance Index: 11.1800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5943
    Cell Significance Index: 324.5700
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.5890
    Cell Significance Index: 3.6600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5657
    Cell Significance Index: 66.7100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4740
    Cell Significance Index: 46.8900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4677
    Cell Significance Index: 26.2500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4459
    Cell Significance Index: 20.7900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4407
    Cell Significance Index: 33.8200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4358
    Cell Significance Index: 30.1400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4070
    Cell Significance Index: 14.3000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4030
    Cell Significance Index: 55.3500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3138
    Cell Significance Index: 59.7200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3040
    Cell Significance Index: 6.4800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2873
    Cell Significance Index: 8.0300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.2151
    Cell Significance Index: 7.4800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.2140
    Cell Significance Index: 3.1600
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.1732
    Cell Significance Index: 2.2300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.1205
    Cell Significance Index: 13.7600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1180
    Cell Significance Index: 181.6500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1112
    Cell Significance Index: 14.2600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0762
    Cell Significance Index: 103.5500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0413
    Cell Significance Index: 77.7200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0197
    Cell Significance Index: 12.5000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0181
    Cell Significance Index: 3.0900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0180
    Cell Significance Index: 33.1700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0101
    Cell Significance Index: 4.5800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.0092
    Cell Significance Index: 0.1000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0065
    Cell Significance Index: 4.8000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0049
    Cell Significance Index: 0.1300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0068
    Cell Significance Index: -5.0200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0084
    Cell Significance Index: -5.2300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0102
    Cell Significance Index: -7.0600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0281
    Cell Significance Index: -21.2500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0318
    Cell Significance Index: -17.9300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0464
    Cell Significance Index: -4.7400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0484
    Cell Significance Index: -0.8100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0515
    Cell Significance Index: -18.4800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0527
    Cell Significance Index: -15.1700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0556
    Cell Significance Index: -1.7800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0584
    Cell Significance Index: -6.6900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0636
    Cell Significance Index: -13.4100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0795
    Cell Significance Index: -11.5600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0945
    Cell Significance Index: -1.5900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1067
    Cell Significance Index: -12.4400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.1175
    Cell Significance Index: -23.5700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1279
    Cell Significance Index: -3.4200
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: -0.1358
    Cell Significance Index: -0.5200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1514
    Cell Significance Index: -7.6500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1627
    Cell Significance Index: -3.5300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1815
    Cell Significance Index: -18.9000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1995
    Cell Significance Index: -2.0700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2155
    Cell Significance Index: -4.5100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.2505
    Cell Significance Index: -2.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2545
    Cell Significance Index: -20.1600
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2575
    Cell Significance Index: -3.8000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2840
    Cell Significance Index: -7.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2850
    Cell Significance Index: -17.5200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3163
    Cell Significance Index: -9.3200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3264
    Cell Significance Index: -6.3700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3486
    Cell Significance Index: -21.3700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3838
    Cell Significance Index: -4.3600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3863
    Cell Significance Index: -20.1200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **G2 Checkpoint Kinase Function**: WEE1 is a G2 checkpoint kinase that regulates the cell cycle by phosphorylating and inactivating key proteins involved in the G1/S and G2/M transitions. 2. **Negative Regulation of Cell Cycle Transitions**: WEE1 negatively regulates the G1/S and G2/M transitions, preventing cells from entering mitosis with damaged DNA. 3. **DNA Damage Response**: WEE1 is involved in the DNA damage response, particularly during the G2/M checkpoint, where it phosphorylates and inactivates proteins that promote cell cycle progression. 4. **Protein Tyrosine Kinase Activity**: WEE1 possesses protein tyrosine kinase activity, which is involved in various cellular processes, including cell signaling and protein interactions. 5. **Expression in Various Cell Types**: WEE1 is expressed in a range of cell types, including stem cells, epithelial cells, immune cells, and cancer cells. **Pathways and Functions:** 1. **Cell Cycle Checkpoints**: WEE1 is involved in the G2/M checkpoint, where it regulates the transition from the G2 phase to mitosis. 2. **DNA Damage Response**: WEE1 phosphorylates and inactivates proteins involved in the DNA damage response, preventing cells from entering mitosis with damaged DNA. 3. **Protein Phosphorylation**: WEE1 phosphorylates and regulates the activity of various proteins, including kinases and phosphatases, involved in cell cycle regulation and DNA damage response. 4. **Cell Polarity Establishment**: WEE1 is involved in the establishment of cell polarity, particularly in epithelial cells. 5. **Protein Tyrosine Kinase Activity**: WEE1's protein tyrosine kinase activity is involved in various cellular processes, including cell signaling and protein interactions. **Clinical Significance:** 1. **Cancer Therapy**: WEE1 is a promising target for cancer therapy, particularly for cancers with impaired G2/M checkpoints, such as certain types of leukemia and lymphoma. 2. **Genetic Disorders**: Mutations in the WEE1 gene have been associated with genetic disorders, including breast cancer and other types of cancer. 3. **Cellular Stress Response**: WEE1's role in the DNA damage response makes it an important regulator of cellular stress response, particularly in the context of chemotherapy and radiation therapy. 4. **Regulation of Stem Cell Proliferation**: WEE1's expression in stem cells suggests that it plays a role in regulating stem cell proliferation and differentiation. In conclusion, WEE1 is a critical kinase involved in the regulation of the cell cycle, DNA damage response, and protein tyrosine kinase activity. Its role in various cellular processes makes it a promising target for cancer therapy and a potential regulator of stem cell proliferation and differentiation.

Genular Protein ID: 1405774488

Symbol: WEE1_HUMAN

Name: Wee1-like protein kinase

UniProtKB Accession Codes:

P30291 B3KVE1 D3DQV0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 2 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 8 DrugCentral 1 EC 1 EMBL 9 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 22 PDBsum 22 PIR 1 PIRSF 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 7 RefSeq 2 Rhea 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7743995

Title: Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle.

PubMed ID: 7743995

DOI: 10.1002/j.1460-2075.1995.tb07180.x

PubMed ID: 11528126

Title: Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1).

PubMed ID: 11528126

DOI: 10.1159/000056998

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 1840647

Title: Wee1(+)-like gene in human cells.

PubMed ID: 1840647

DOI: 10.1038/353080a0

PubMed ID: 8348613

Title: Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase.

PubMed ID: 8348613

DOI: 10.1016/0092-8674(93)80048-j

PubMed ID: 8428596

Title: Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15.

PubMed ID: 8428596

DOI: 10.1002/j.1460-2075.1993.tb05633.x

PubMed ID: 15150265

Title: Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function.

PubMed ID: 15150265

DOI: 10.1074/jbc.m404728200

PubMed ID: 15070733

Title: M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.

PubMed ID: 15070733

DOI: 10.1073/pnas.0307700101

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20026642

Title: Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity.

PubMed ID: 20026642

DOI: 10.1242/jcs.058230

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22692537

Title: Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit.

PubMed ID: 22692537

DOI: 10.1038/ncomms1886

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 33108758

Title: CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress.

PubMed ID: 33108758

DOI: 10.1016/j.molcel.2020.10.008

PubMed ID: 15837193

Title: Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypical tyrosine kinase with a key role in CDK1 regulation.

PubMed ID: 15837193

DOI: 10.1016/j.str.2004.12.017

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 646
  • Mass: 71597
  • Checksum: DB00623D304562A0
  • Sequence:
    • MSFLSRQQPP PPRRAGAACT LRQKLIFSPC SDCEEEEEEE EEEGSGHSTG EDSAFQEPDS 
PLPPARSPTE PGPERRRSPG PAPGSPGELE EDLLLPGACP GADEAGGGAE GDSWEEEGFG 
SSSPVKSPAA PYFLGSSFSP VRCGGPGDAS PRGCGARRAG EGRRSPRPDH PGTPPHKTFR 
KLRLFDTPHT PKSLLSKARG IDSSSVKLRG SSLFMDTEKS GKREFDVRQT PQVNINPFTP 
DSLLLHSSGQ CRRRKRTYWN DSCGEDMEAS DYELEDETRP AKRITITESN MKSRYTTEFH 
ELEKIGSGEF GSVFKCVKRL DGCIYAIKRS KKPLAGSVDE QNALREVYAH AVLGQHSHVV 
RYFSAWAEDD HMLIQNEYCN GGSLADAISE NYRIMSYFKE AELKDLLLQV GRGLRYIHSM 
SLVHMDIKPS NIFISRTSIP NAASEEGDED DWASNKVMFK IGDLGHVTRI SSPQVEEGDS 
RFLANEVLQE NYTHLPKADI FALALTVVCA AGAEPLPRNG DQWHEIRQGR LPRIPQVLSQ 
EFTELLKVMI HPDPERRPSA MALVKHSVLL SASRKSAEQL RIELNAEKFK NSLLQKELKK 
AQMAKAAAEE RALFTDRMAT RSTTQSNRTS RLIGKKMNRS VSLTIY

Genular Protein ID: 2964083913

Symbol: Q86V29_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86V29

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 7 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 3 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 Rhea 3 SAM 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 646
  • Mass: 71650
  • Checksum: 96716238344462A9
  • Sequence:
    • MSFLSRQQPP PPRRAGAACT LRQKLIFSPC SDCEEEEEEE EEEGSGHSTG EDSAFQEPDS 
PLPPARSPTE PGPERRRSPG PAPGSPGELE EDLLLPGACP GADEAGGGAE GDSWEEEGFG 
SSSPVKSPAA PYFLGSSFSP VRCGGPGDAS PRGCGARRAG EGRRSPRPDH PGTPPHKTFR 
KLRLFDTPHT PKSLLSKARG IDSSSVKLRG SSLFMDTEKS GKREFDVRQT PQVNINPFTP 
DSLLLHSSGQ CRRRKRTYWN DSCGEDMEAS DYELEDETRP AKRITITESN MKSRYTTEFH 
ELEKIGSGEF GSVFKCVKRL DGCIYAIKRS KKPLAGSVDE QNALREVYAH AVLGQHSHVV 
RYFSAWAEDD HMLIQNEYRN GGSLADAISE NYRIMSYFKE AELKDLLLQV GRGLRYIHSM 
SLVHMDIKPS NIFISRTSIP NAASEEGDED DWASNKVMFK IGDLGHVTRI SSPQVEEGDS 
RFLANEVLQE NYTHLPKADI FALALTVVCA AGAEPLPRNG DQWHEIRQGR LPRIPQVLSQ 
EFTELLKVMI HPDPERRPSA MALVKHSVLL SASRKSAEQL RIELNAEKFK NSLLQKELKK 
AQMAKAAAEE RALFTDRMAT RSTTQSNRTS RLIGKKMNRS VSLTIY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.