Details for: ZNF148
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 483.9428
Cell Significance Index: -75.2800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 298.6476
Cell Significance Index: -75.7500 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 207.1137
Cell Significance Index: -85.3200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 172.1587
Cell Significance Index: -81.2800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 164.2310
Cell Significance Index: -66.7200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 148.7795
Cell Significance Index: -76.5300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 70.1341
Cell Significance Index: -66.9600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 63.9439
Cell Significance Index: -78.8400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 27.5864
Cell Significance Index: -73.9000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 24.2556
Cell Significance Index: -74.5000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 20.2050
Cell Significance Index: -79.7300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 18.5097
Cell Significance Index: -40.5100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.7489
Cell Significance Index: 154.2600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.5382
Cell Significance Index: 509.1600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.4436
Cell Significance Index: 484.9500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 2.3172
Cell Significance Index: 177.8200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.2764
Cell Significance Index: 816.5000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 2.1290
Cell Significance Index: 130.8600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.9323
Cell Significance Index: 1336.4200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 1.8707
Cell Significance Index: 44.8700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.8320
Cell Significance Index: 47.0900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.5070
Cell Significance Index: 66.6600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.4379
Cell Significance Index: 54.4500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.4319
Cell Significance Index: 96.2800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.3018
Cell Significance Index: 36.3800 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.2261
Cell Significance Index: 23.9300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.1682
Cell Significance Index: 24.9700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.9740
Cell Significance Index: 175.5800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.9113
Cell Significance Index: 112.0500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.7347
Cell Significance Index: 100.9000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6773
Cell Significance Index: 611.5500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.6323
Cell Significance Index: 345.3000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.5539
Cell Significance Index: 38.3100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4682
Cell Significance Index: 206.9900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.4581
Cell Significance Index: 21.3600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.4522
Cell Significance Index: 23.5600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4385
Cell Significance Index: 71.3200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.4034
Cell Significance Index: 759.6200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3678
Cell Significance Index: 16.6700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3542
Cell Significance Index: 10.2100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.3419
Cell Significance Index: 5.8600 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.2858
Cell Significance Index: 3.5500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.2816
Cell Significance Index: 127.8000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.2670
Cell Significance Index: 7.6200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2637
Cell Significance Index: 167.4600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2464
Cell Significance Index: 454.4000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2419
Cell Significance Index: 372.3600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1358
Cell Significance Index: 184.6400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1138
Cell Significance Index: 14.5900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0804
Cell Significance Index: 15.3000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0779
Cell Significance Index: 9.1900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0692
Cell Significance Index: 1.8600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0420
Cell Significance Index: 7.1700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0270
Cell Significance Index: 0.9500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0071
Cell Significance Index: 0.1900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0006
Cell Significance Index: 0.0300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0243
Cell Significance Index: -18.0000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0251
Cell Significance Index: -2.4800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0269
Cell Significance Index: -19.7600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0499
Cell Significance Index: -1.0800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0679
Cell Significance Index: -42.4000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0883
Cell Significance Index: -66.8700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0965
Cell Significance Index: -54.4500 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.1439
Cell Significance Index: -2.0700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1700
Cell Significance Index: -10.9700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2014
Cell Significance Index: -26.0200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2209
Cell Significance Index: -22.5600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2308
Cell Significance Index: -48.6000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.2362
Cell Significance Index: -25.7000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2386
Cell Significance Index: -27.8100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2403
Cell Significance Index: -69.1500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2477
Cell Significance Index: -36.0000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3805
Cell Significance Index: -19.9800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3982
Cell Significance Index: -28.1600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4082
Cell Significance Index: -25.7300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.4294
Cell Significance Index: -6.3400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4375
Cell Significance Index: -45.5500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4460
Cell Significance Index: -33.2400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4733
Cell Significance Index: -54.2300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.4903
Cell Significance Index: -25.4700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5588
Cell Significance Index: -11.9000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.5702
Cell Significance Index: -3.4500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.6489
Cell Significance Index: -74.0700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.7093
Cell Significance Index: -17.7300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.7161
Cell Significance Index: -11.9900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7511
Cell Significance Index: -26.1000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.7934
Cell Significance Index: -25.4100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.8071
Cell Significance Index: -63.9200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.8563
Cell Significance Index: -18.7500 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.9035
Cell Significance Index: -10.7700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.9861
Cell Significance Index: -16.6100 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -1.0222
Cell Significance Index: -24.9400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -1.0694
Cell Significance Index: -28.1200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.1412
Cell Significance Index: -69.9700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.1865
Cell Significance Index: -23.4600 - Cell Name: peg cell (CL4033014)
Fold Change: -1.2526
Cell Significance Index: -28.9400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.2663
Cell Significance Index: -41.4600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -1.2774
Cell Significance Index: -34.7700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.3077
Cell Significance Index: -41.6500 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -1.3638
Cell Significance Index: -19.5900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 893928357
Symbol: ZN148_HUMAN
Name: Zinc finger protein 148
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9457682
Title: The human ZBP-89 homolog, located at chromosome 3q21, represses gastrin gene expression.
PubMed ID: 9457682
PubMed ID: 10359087
Title: Human stromelysin gene promoter activity is modulated by transcription factor ZBP-89.
PubMed ID: 10359087
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15190078
Title: Regulation of murine cytochrome c oxidase Vb gene expression during myogenesis: YY-1 and heterogeneous nuclear ribonucleoprotein D-like protein (JKTBP1) reciprocally regulate transcription activity by physical interaction with the BERF-1/ZBP-89 factor.
PubMed ID: 15190078
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 27964749
Title: Truncating de novo mutations in the Krueppel-type zinc-finger gene ZNF148 in patients with corpus callosum defects, developmental delay, short stature, and dysmorphisms.
PubMed ID: 27964749
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 794
- Mass: 88976
- Checksum: 50413723459EBD1F
- Sequence:
MNIDDKLEGL FLKCGGIDEM QSSRTMVVMG GVSGQSTVSG ELQDSVLQDR SMPHQEILAA DEVLQESEMR QQDMISHDEL MVHEETVKND EEQMETHERL PQGLQYALNV PISVKQEITF TDVSEQLMRD KKQIREPVDL QKKKKRKQRS PAKILTINED GSLGLKTPKS HVCEHCNAAF RTNYHLQRHV FIHTGEKPFQ CSQCDMRFIQ KYLLQRHEKI HTGEKPFRCD ECGMRFIQKY HMERHKRTHS GEKPYQCEYC LQYFSRTDRV LKHKRMCHEN HDKKLNRCAI KGGLLTSEED SGFSTSPKDN SLPKKKRQKT EKKSSGMDKE SALDKSDLKK DKNDYLPLYS SSTKVKDEYM VAEYAVEMPH SSVGGSHLED ASGEIHPPKL VLKKINSKRS LKQPLEQNQT ISPLSTYEES KVSKYAFELV DKQALLDSEG NADIDQVDNL QEGPSKPVHS STNYDDAMQF LKKKRYLQAA SNNSREYALN VGTIASQPSV TQAAVASVID ESTTASILES QALNVEIKSN HDKNVIPDEV LQTLLDHYSH KANGQHEISF SVADTEVTSS ISINSSEVPE VTPSENVGSS SQASSSDKAN MLQEYSKFLQ QALDRTSQND AYLNSPSLNF VTDNQTLPNQ PAFSSIDKQV YATMPINSFR SGMNSPLRTT PDKSHFGLIV GDSQHSFPFS GDETNHASAT STQDFLDQVT SQKKAEAQPV HQAYQMSSFE QPFRAPYHGS RAGIATQFST ANGQVNLRGP GTSAEFSEFP LVNVNDNRAG MTSSPDATTG QTFG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.