Details for: ZYX

Gene ID: 7791

Symbol: ZYX

Ensembl ID: ENSG00000159840

Description: zyxin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 268.2178
    Cell Significance Index: -41.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 137.9890
    Cell Significance Index: -35.0000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 103.5551
    Cell Significance Index: -42.0700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 90.6544
    Cell Significance Index: -42.8000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 86.2583
    Cell Significance Index: -44.3700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 64.3347
    Cell Significance Index: -43.1700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 44.4832
    Cell Significance Index: -42.4700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 33.8455
    Cell Significance Index: -41.7300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.6691
    Cell Significance Index: -31.2600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.6385
    Cell Significance Index: -41.9800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.6664
    Cell Significance Index: -29.6900
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 8.7663
    Cell Significance Index: 54.2400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.9399
    Cell Significance Index: -13.0000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 5.8660
    Cell Significance Index: 146.2800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 5.5503
    Cell Significance Index: 102.5900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 4.2399
    Cell Significance Index: 124.5200
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 2.5881
    Cell Significance Index: 17.1700
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 2.4781
    Cell Significance Index: 13.0400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.5063
    Cell Significance Index: 31.5300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.3394
    Cell Significance Index: 183.9400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2125
    Cell Significance Index: 1094.8000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.0988
    Cell Significance Index: 141.9600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.0730
    Cell Significance Index: 126.5500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9924
    Cell Significance Index: 13.5400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.9736
    Cell Significance Index: 72.5600
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.9522
    Cell Significance Index: 12.2000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.9269
    Cell Significance Index: 26.5700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.9177
    Cell Significance Index: 24.9800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8698
    Cell Significance Index: 40.8800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.8674
    Cell Significance Index: 9.4300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8036
    Cell Significance Index: 87.4000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7565
    Cell Significance Index: 53.5000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7321
    Cell Significance Index: 43.9500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7000
    Cell Significance Index: 140.4200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6979
    Cell Significance Index: 36.3600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6756
    Cell Significance Index: 19.4700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6550
    Cell Significance Index: 64.7900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5886
    Cell Significance Index: 95.7300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4920
    Cell Significance Index: 10.6600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4663
    Cell Significance Index: 206.1600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4110
    Cell Significance Index: 50.5400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3882
    Cell Significance Index: 211.9800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3771
    Cell Significance Index: 26.0800
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.3522
    Cell Significance Index: 4.9400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3279
    Cell Significance Index: 21.1500
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 0.2914
    Cell Significance Index: 1.8600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2862
    Cell Significance Index: 54.4600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2550
    Cell Significance Index: 45.9800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1772
    Cell Significance Index: 8.9600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1433
    Cell Significance Index: 5.0400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1314
    Cell Significance Index: 47.1300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1022
    Cell Significance Index: 70.6900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0906
    Cell Significance Index: 11.6200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0143
    Cell Significance Index: 0.2400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0135
    Cell Significance Index: 0.3600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0110
    Cell Significance Index: 0.5000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0108
    Cell Significance Index: 1.8500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0024
    Cell Significance Index: -0.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0049
    Cell Significance Index: -9.1800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0059
    Cell Significance Index: -1.1700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0171
    Cell Significance Index: -31.5100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0183
    Cell Significance Index: -13.5400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0208
    Cell Significance Index: -32.0200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0278
    Cell Significance Index: -17.3800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0285
    Cell Significance Index: -38.7100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0339
    Cell Significance Index: -15.4000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0373
    Cell Significance Index: -28.2300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0490
    Cell Significance Index: -27.6100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0530
    Cell Significance Index: -38.8900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0591
    Cell Significance Index: -37.5500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0734
    Cell Significance Index: -1.9300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0948
    Cell Significance Index: -19.9600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1107
    Cell Significance Index: -12.6800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1219
    Cell Significance Index: -6.3300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1227
    Cell Significance Index: -35.3000
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.1355
    Cell Significance Index: -2.4000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1479
    Cell Significance Index: -1.6800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1649
    Cell Significance Index: -19.2200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1708
    Cell Significance Index: -4.2700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1742
    Cell Significance Index: -8.1200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2358
    Cell Significance Index: -34.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2729
    Cell Significance Index: -8.7400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.2964
    Cell Significance Index: -2.4900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2979
    Cell Significance Index: -22.8600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3124
    Cell Significance Index: -8.7300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3402
    Cell Significance Index: -13.9400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3600
    Cell Significance Index: -37.4800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3634
    Cell Significance Index: -41.4800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3824
    Cell Significance Index: -20.0800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4829
    Cell Significance Index: -10.2900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4887
    Cell Significance Index: -12.4900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.5296
    Cell Significance Index: -3.2000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5422
    Cell Significance Index: -42.9400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5598
    Cell Significance Index: -34.3200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5979
    Cell Significance Index: -11.6700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6347
    Cell Significance Index: -40.0100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6622
    Cell Significance Index: -21.0900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6890
    Cell Significance Index: -38.6700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.7459
    Cell Significance Index: -26.1300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.7545
    Cell Significance Index: -11.3100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cell Adhesion**: Zyxin is a key regulator of cell adhesion, particularly in adherens junctions and focal adhesions, where it interacts with cytoskeletal proteins and adhesion molecules to maintain cell-cell and cell-matrix interactions. 2. **Cytoskeletal Dynamics**: Zyxin is involved in the assembly and disassembly of stress fibers and focal adhesions, which are critical for cell migration, proliferation, and differentiation. 3. **Immune Response**: Zyxin is expressed in immune cells, including classical monocytes and T cells, where it regulates immune response by modulating cytokine signaling and phagocytic activity. 4. **Protein Binding**: Zyxin interacts with a range of proteins, including actin, myosin, and adhesion molecules, to regulate its functions. **Pathways and Functions:** 1. **Actin Cytoskeleton**: Zyxin regulates actin filament assembly and disassembly, which is essential for cell migration, proliferation, and differentiation. 2. **Adherens Junction**: Zyxin interacts with adhesion molecules to maintain cell-cell adhesion and regulate cell-cell signaling. 3. **Cell-Matrix Adhesion**: Zyxin regulates cell-matrix adhesion by interacting with integrins and other adhesion molecules. 4. **Integrin-Mediated Signaling Pathway**: Zyxin modulates integrin signaling, which is critical for cell migration, proliferation, and differentiation. 5. **Transforming Growth Factor Beta (TGF-β) Signaling Pathway**: Zyxin regulates TGF-β signaling, which is involved in cell differentiation, proliferation, and apoptosis. **Clinical Significance:** 1. **Immunological Disorders**: Dysregulation of Zyxin has been implicated in various immunological disorders, including autoimmune diseases, cancer, and infectious diseases. 2. **Tissue Repair**: Zyxin plays a crucial role in tissue repair and regeneration, particularly in the context of wound healing and fibrosis. 3. **Cancer Progression**: Zyxin is involved in cancer progression, where it regulates cell migration, invasion, and metastasis. 4. **Infectious Diseases**: Zyxin modulates immune response to infectious diseases, including bacterial and viral infections. In conclusion, Zyxin is a multifunctional protein that plays a critical role in regulating cell adhesion, cytoskeletal dynamics, and immune response. Its dysregulation has been implicated in various immunological disorders, tissue repair, cancer progression, and infectious diseases, highlighting its importance in maintaining tissue homeostasis and regulating immune function. Further research is necessary to fully elucidate the mechanisms by which Zyxin regulates these processes and to explore its therapeutic potential.

Genular Protein ID: 1440243153

Symbol: ZYX_HUMAN

Name: Zyxin

UniProtKB Accession Codes:

Q15942 A4D2G6 B4DQX7 Q6I9S4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CPTAC 3 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 11 Ensembl 4 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8940160

Title: Molecular characterization of human zyxin.

PubMed ID: 8940160

DOI: 10.1074/jbc.271.49.31470

PubMed ID: 8917469

Title: A zyxin-related protein whose synthesis is reduced in virally transformed fibroblasts.

PubMed ID: 8917469

DOI: 10.1111/j.1432-1033.1996.00657.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10801818

Title: Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins.

PubMed ID: 10801818

DOI: 10.1074/jbc.m001698200

PubMed ID: 11689660

Title: Interaction of zyxin, a focal adhesion protein, with the E6 protein from human papillomavirus type 6 results in its nuclear translocation.

PubMed ID: 11689660

DOI: 10.1128/jvi.75.23.11791-11802.2001

PubMed ID: 12695497

Title: The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions.

PubMed ID: 12695497

DOI: 10.1083/jcb.200211015

PubMed ID: 16885336

Title: Myopodin-mediated suppression of prostate cancer cell migration involves interaction with zyxin.

PubMed ID: 16885336

DOI: 10.1158/0008-5472.can-06-0227

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 18158903

Title: Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding.

PubMed ID: 18158903

DOI: 10.1016/j.molcel.2007.10.033

PubMed ID: 18297730

Title: The LIM-domain protein zyxin binds the homeodomain factor Xanf1/Hesx1 and modulates its activity in the anterior neural plate of Xenopus laevis embryo.

PubMed ID: 18297730

DOI: 10.1002/dvdy.21471

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 572
  • Mass: 61277
  • Checksum: 2833B1EFA260B762
  • Sequence:
    • MAAPRPSPAI SVSVSAPAFY APQKKFGPVV APKPKVNPFR PGDSEPPPAP GAQRAQMGRV 
GEIPPPPPED FPLPPPPLAG DGDDAEGALG GAFPPPPPPI EESFPPAPLE EEIFPSPPPP 
PEEEGGPEAP IPPPPQPREK VSSIDLEIDS LSSLLDDMTK NDPFKARVSS GYVPPPVATP 
FSSKSSTKPA AGGTAPLPPW KSPSSSQPLP QVPAPAQSQT QFHVQPQPQP KPQVQLHVQS 
QTQPVSLANT QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE 
ALSAGTGSPQ PPSFTYAQQR EKPRVQEKQH PVPPPAQNQN QVRSPGAPGP LTLKEVEELE 
QLTQQLMQDM EHPQRQNVAV NELCGRCHQP LARAQPAVRA LGQLFHIACF TCHQCAQQLQ 
GQQFYSLEGA PYCEGCYTDT LEKCNTCGEP ITDRMLRATG KAYHPHCFTC VVCARPLEGT 
SFIVDQANRP HCVPDYHKQY APRCSVCSEP IMPEPGRDET VRVVALDKNF HMKCYKCEDC 
GKPLSIEADD NGCFPLDGHV LCRKCHTARA QT

Genular Protein ID: 4192510344

Symbol: Q96AF9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96AF9

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 2 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 466
  • Mass: 50472
  • Checksum: 94FCC8FF8D5F15B1
  • Sequence:
    • RPLSSPSLLL PCVPPEEEGG PEAPIPPPPQ PREKVSSIDL EIDSLSSLLD DMTKNDPFKA 
RVSSGYVPPP VATPFSSKSS TKPAAGGTAP LPPWKSPSSS QPLPQVPAPA QSQTQFHVQP 
QPQPKPQVQL HVQSQTQPVS LANTQPRGPP ASSPAPAPKF SPVTPKFTPV ASKFSPGAPG 
GSGSQPNQKL GHPEALSAGT GSPQPPSFTY AQQREKPRVQ EKQHPVPPPA QNQNQVRSPG 
APGPLTLKEV EELEQLTQQL MQDMEHPQRQ NVAVNELCGR CHQPLARAQP AVRALGQLFH 
IACFTCHQCA QQLQGQQFYS LEGAPYCEGC YTDTLEKCNT CGEPITDRML RATGKAYHPH 
CFTCVVCARP LEGTSFIVDQ ANRPHCVPDY HKQYAPRCSV CSEPIMPEPG RDETVRVVAL 
DKNFHMKCYK CEDCGKPLSI EADDNGCFPL DGHVLCRKCH TARAQT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.