Details for: NCOA4

Gene ID: 8031

Symbol: NCOA4

Ensembl ID: ENSG00000266412

Description: nuclear receptor coactivator 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 94.6965
    Cell Significance Index: -39.0100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 90.0415
    Cell Significance Index: -36.5800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 83.8236
    Cell Significance Index: -39.5800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 77.8405
    Cell Significance Index: -40.0400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 58.8691
    Cell Significance Index: -39.5000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 38.6020
    Cell Significance Index: -36.8600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.8497
    Cell Significance Index: -34.4200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.0111
    Cell Significance Index: -33.8200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.4614
    Cell Significance Index: -16.3300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 4.2354
    Cell Significance Index: 43.8500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.6994
    Cell Significance Index: 49.8900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.5668
    Cell Significance Index: 35.0200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.2876
    Cell Significance Index: 248.8200
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 2.1743
    Cell Significance Index: 13.8800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4582
    Cell Significance Index: 289.3800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3209
    Cell Significance Index: 162.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 1.2015
    Cell Significance Index: 122.7400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.1947
    Cell Significance Index: 215.3800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9664
    Cell Significance Index: 45.0600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.8714
    Cell Significance Index: 23.3100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.8164
    Cell Significance Index: 57.7400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7909
    Cell Significance Index: 54.7000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7274
    Cell Significance Index: 46.9300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7248
    Cell Significance Index: 654.4300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7122
    Cell Significance Index: 142.8700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6669
    Cell Significance Index: 91.5900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6626
    Cell Significance Index: 361.8400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6127
    Cell Significance Index: 270.9000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.5908
    Cell Significance Index: 27.7700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5416
    Cell Significance Index: 28.2100
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.5215
    Cell Significance Index: 3.4600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5108
    Cell Significance Index: 60.2400
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.4918
    Cell Significance Index: 5.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4749
    Cell Significance Index: 61.3600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4558
    Cell Significance Index: 23.6800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3728
    Cell Significance Index: 16.9000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.3616
    Cell Significance Index: 3.3300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.3569
    Cell Significance Index: 40.7400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3458
    Cell Significance Index: 65.8100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.3340
    Cell Significance Index: 24.8900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3169
    Cell Significance Index: 113.6800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3079
    Cell Significance Index: 8.3800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3025
    Cell Significance Index: 38.7800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2571
    Cell Significance Index: 25.4300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2351
    Cell Significance Index: 18.0400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2342
    Cell Significance Index: 39.9900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1460
    Cell Significance Index: 5.0800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1161
    Cell Significance Index: 18.8800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0390
    Cell Significance Index: 1.3700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0318
    Cell Significance Index: 23.3000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0243
    Cell Significance Index: 18.3600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0240
    Cell Significance Index: 0.3600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0163
    Cell Significance Index: 30.6900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0045
    Cell Significance Index: 0.1200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0030
    Cell Significance Index: 0.0800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0001
    Cell Significance Index: 0.0400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0041
    Cell Significance Index: -3.0500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0175
    Cell Significance Index: -26.9100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0182
    Cell Significance Index: -33.6000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0207
    Cell Significance Index: -13.1700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0221
    Cell Significance Index: -30.0800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0367
    Cell Significance Index: -20.7100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0397
    Cell Significance Index: -8.3700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0474
    Cell Significance Index: -21.5300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0630
    Cell Significance Index: -1.8200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0983
    Cell Significance Index: -2.5100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1354
    Cell Significance Index: -38.9500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1363
    Cell Significance Index: -19.8100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1385
    Cell Significance Index: -15.8700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1436
    Cell Significance Index: -7.5400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1800
    Cell Significance Index: -12.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1956
    Cell Significance Index: -12.0200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2169
    Cell Significance Index: -4.7000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2420
    Cell Significance Index: -6.0500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2502
    Cell Significance Index: -8.0100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2545
    Cell Significance Index: -29.6600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2937
    Cell Significance Index: -23.2600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3224
    Cell Significance Index: -18.0900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3298
    Cell Significance Index: -34.3500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3387
    Cell Significance Index: -5.7100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3813
    Cell Significance Index: -24.0300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3962
    Cell Significance Index: -6.6300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.4072
    Cell Significance Index: -7.2000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4330
    Cell Significance Index: -26.5500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.4402
    Cell Significance Index: -3.5200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4578
    Cell Significance Index: -9.7500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4605
    Cell Significance Index: -9.6400
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4735
    Cell Significance Index: -10.9400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4978
    Cell Significance Index: -7.3500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5008
    Cell Significance Index: -14.3600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5103
    Cell Significance Index: -22.5700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.5364
    Cell Significance Index: -14.9900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5797
    Cell Significance Index: -14.9000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6161
    Cell Significance Index: -23.3300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6445
    Cell Significance Index: -11.0500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.6598
    Cell Significance Index: -8.4500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6885
    Cell Significance Index: -20.2800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7047
    Cell Significance Index: -17.2000
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.7719
    Cell Significance Index: -12.7200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.7755
    Cell Significance Index: -22.1300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** NCOA4 is highly expressed in tracheal goblet cells, kidney proximal convoluted tubule epithelial cells, and myeloid leukocytes, suggesting its role in maintaining epithelial and immune system function. 2. **Function:** As a transcription coactivator, NCOA4 enhances the transcriptional activity of nuclear receptors, including estrogen and testosterone receptors, thereby regulating gene expression in response to hormonal stimuli. 3. **Cellular Localization:** NCOA4 is primarily localized to the nucleus, where it interacts with nuclear receptors and other transcriptional coactivators to regulate gene expression. 4. **Signaling Pathways:** NCOA4 is involved in multiple signaling pathways, including autolysosome, intracellular estrogen receptor signaling, and male gonad development, highlighting its role in regulating cellular homeostasis and responding to hormonal stimuli. **Pathways and Functions:** 1. **Intracellular Estrogen Receptor Signaling Pathway:** NCOA4 enhances the transcriptional activity of estrogen receptors, regulating gene expression in response to estrogen stimulation. 2. **Intracellular Iron Ion Homeostasis:** NCOA4 is involved in regulating iron ion homeostasis, which is essential for maintaining cellular function and preventing iron toxicity. 3. **Autolysosome Pathway:** NCOA4 is involved in regulating autolysosome formation and function, which is critical for maintaining cellular homeostasis and responding to cellular stress. 4. **Male Gonad Development:** NCOA4 plays a crucial role in regulating male gonad development, highlighting its importance in reproductive health. **Clinical Significance:** 1. **Reproductive Health:** NCOA4's involvement in male gonad development underscores its importance in reproductive health, particularly in cases of hormonal imbalances or reproductive disorders. 2. **Cancer:** NCOA4's role in regulating gene expression and cellular homeostasis makes it a potential target for cancer therapy, particularly in cases of hormone-dependent cancers. 3. **Immunological Disorders:** NCOA4's involvement in myeloid leukocyte function highlights its importance in immune system regulation, particularly in cases of immunological disorders, such as autoimmune diseases or leukemias. 4. **Neurological Disorders:** NCOA4's role in regulating gene expression and cellular homeostasis makes it a potential target for neurological disorders, such as neurodegenerative diseases or psychiatric disorders. In conclusion, NCOA4 is a critical gene involved in regulating gene expression and cellular homeostasis. Its involvement in multiple signaling pathways, including autolysosome, intracellular estrogen receptor signaling, and male gonad development, underscores its importance in maintaining cellular homeostasis and responding to hormonal stimuli. Further research is needed to fully elucidate NCOA4's role in various diseases and to explore its potential as a therapeutic target.

Genular Protein ID: 270700413

Symbol: NCOA4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q13772 A8K8W5 B4E260 E9PAV7 J3KQN8 Q14239

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 5 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8643607

Title: Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

PubMed ID: 8643607

DOI: 10.1073/pnas.93.11.5517

PubMed ID: 8290261

Title: Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma.

PubMed ID: 8290261

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8187085

Title: Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas.

PubMed ID: 8187085

PubMed ID: 9892017

Title: Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform.

PubMed ID: 9892017

DOI: 10.1210/mend.13.1.0214

PubMed ID: 10347167

Title: Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma.

PubMed ID: 10347167

DOI: 10.1074/jbc.274.23.16147

PubMed ID: 10517667

Title: RFG (ARA70, ELE1) interacts with the human androgen receptor in a ligand-dependent fashion, but functions only weakly as a coactivator in cotransfection assays.

PubMed ID: 10517667

DOI: 10.1210/mend.13.10.0352

PubMed ID: 24910095

Title: NCOA4 transcriptional coactivator inhibits activation of DNA replication origins.

PubMed ID: 24910095

DOI: 10.1016/j.molcel.2014.04.031

PubMed ID: 25327288

Title: Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.

PubMed ID: 25327288

DOI: 10.1038/ncb3053

PubMed ID: 26436293

Title: Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis.

PubMed ID: 26436293

DOI: 10.7554/elife.10308

PubMed ID: 15563469

Title: The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor.

PubMed ID: 15563469

DOI: 10.1074/jbc.m407046200

Sequence Information:

  • Length: 614
  • Mass: 69726
  • Checksum: 36B6D97C7D072BFF
  • Sequence:
    • MNTFQDQSGS SSNREPLLRC SDARRDLELA IGGVLRAEQQ IKDNLREVKA QIHSCISRHL 
ECLRSREVWL YEQVDLIYQL KEETLQQQAQ QLYSLLGQFN CLTHQLECTQ NKDLANQVSV 
CLERLGSLTL KPEDSTVLLF EADTITLRQT ITTFGSLKTI QIPEHLMAHA SSANIGPFLE 
KRGCISMPEQ KSASGIVAVP FSEWLLGSKP ASGYQAPYIP STDPQDWLTQ KQTLENSQTS 
SRACNFFNNV GGNLKGLENW LLKSEKSSYQ KCNSHSTTSS FSIEMEKVGD QELPDQDEMD 
LSDWLVTPQE SHKLRKPENG SRETSEKFKL LFQSYNVNDW LVKTDSCTNC QGNQPKGVEI 
ENLGNLKCLN DHLEAKKPLS TPSMVTEDWL VQNHQDPCKV EEVCRANEPC TSFAECVCDE 
NCEKEALYKW LLKKEGKDKN GMPVEPKPEP EKHKDSLNMW LCPRKEVIEQ TKAPKAMTPS 
RIADSFQVIK NSPLSEWLIR PPYKEGSPKE VPGTEDRAGK QKFKSPMNTS WCSFNTADWV 
LPGKKMGNLS QLSSGEDKWL LRKKAQEVLL NSPLQEEHNF PPDHYGLPAV CDLFACMQLK 
VDKEKWLYRT PLQM

Genular Protein ID: 1389479746

Symbol: B2R5V0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R5V0

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 614
  • Mass: 69779
  • Checksum: 781C7862CA0D4311
  • Sequence:
    • MNTFQDQSGS SSNREPLLRC SDARRDLELA IGGVLRAEQQ IKDNLREVKA QIHSCISRHL 
ECLRSREVWL YEQVDLIYQL KEETLQQQAQ QLYSLLGQFN CLTHQLECTQ NKDLANQVSV 
CLERLGSLTL KPEDSTVLLF EADTITLRQT ITTFGSLKTI QIPEHLMAHA SSANIGPFLE 
KRGRISMPEQ KSASGIVAVP FSEWLLGSKP ASGYQAPYIP STDPQDWLTQ KQTLENSQTS 
SRACNFFNNV GGNLKGLENW LLKSEKSSYQ KCNSHSTTSS FSIEMEKVGD QELPDQDEMD 
LSDWLVTPQE SHKLRKPENG SRETSEKFKL LFQSYNVNDW LVKTDSCTNC QGNQPKGVEI 
ENLGNLKCLN DHLEAKKPLS TPSMVTEDWL VQNHQDPCKV EEVCRANEPC TSFAECVCDE 
NCEKEALYKW LLKKEGKDKN GMPVEPKPEP EKHKDSLNMW LCPRKEVIEQ TKAPKAMTPS 
RIADSFQVIK NSPLSEWLIR PPYKEGSPKE VPGTEDRAGK QKFKSPMNTS WCSFNTADWV 
LPGKKMGNLS QLSSGEDKWL LRKKAQEVLL NSPLQEEHNF PPDHYGLPAV CDLFACMQLK 
VDKEKWLYRT PLQM

Genular Protein ID: 3747231646

Symbol: Q96E88_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96E88

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 ProteomicsDB 1 RefSeq 5 SMR 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 575
  • Mass: 65295
  • Checksum: E5E449EF7CED5F3D
  • Sequence:
    • MNTFQDQSGS SSNREPLLRC SDARRDLELA IGGVLRAEQQ IKDNLREVKA QIHSCISRHL 
ECLRSREVWL YEQVDLIYQL KEETLQQQAQ QLYSLLGQFN CLTHQLECTQ NKDLANQVSV 
CLERLGSLTL KPEDSTVLLF EADTITLRQT ITTFGSLKTI QIPEHLMAHA SSANIGPFLE 
KRGCISMPEQ KSASGIVAVP FSEWLLGSKP ASGYQAPYIP STDPQDWLTQ KQTLENSQTS 
SRACNFFNNV GGNLKGLENW LLKSEKSSYQ KCNSHSTTSS FSIEMEKVGD QELPDQDEMD 
LSDWLVTPQE SHKLRKPENG SRETSEKFKL LFQSYNVNDW LVKTDSCTNC QGNQPKGVEI 
ENLGNLKCLN DHLEAKKPLS TPSMVTEDWL VQNHQDPCKV EEVCRANEPC TSFAECVCDE 
NCEKEALYKW LLKKEGKDKN GMPVEPKPEP EKHKDSLNMW LCPRKEVIEQ TKAPKAMTPS 
RIADSFQVIK NSPLSEWLIR PPYKEGSPKE VPGTEDRAGK QKYYLIHLYR RNITSPQTIM 
ASLQFVISLP VCSLKLIKRS GYIELLYRCE GMDKS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.