Details for: USP5

Gene ID: 8078

Symbol: USP5

Ensembl ID: ENSG00000111667

Description: ubiquitin specific peptidase 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 107.8143
    Cell Significance Index: -16.7700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 71.9514
    Cell Significance Index: -18.2500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 47.6147
    Cell Significance Index: -22.4800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 43.2239
    Cell Significance Index: -17.5600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 40.4366
    Cell Significance Index: -20.8000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 18.6647
    Cell Significance Index: -17.8200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.4888
    Cell Significance Index: -20.3300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.9545
    Cell Significance Index: -18.6300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.3725
    Cell Significance Index: -21.2000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.3364
    Cell Significance Index: 132.2000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.0935
    Cell Significance Index: 14.9200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0727
    Cell Significance Index: 968.5700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.7679
    Cell Significance Index: 89.4900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7603
    Cell Significance Index: 123.6600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7579
    Cell Significance Index: 45.5000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5329
    Cell Significance Index: 27.7600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4831
    Cell Significance Index: 96.9000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4661
    Cell Significance Index: 92.5000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4157
    Cell Significance Index: 21.8300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.3669
    Cell Significance Index: 7.6800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3551
    Cell Significance Index: 18.4500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3282
    Cell Significance Index: 9.4600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.3201
    Cell Significance Index: 3.4800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2889
    Cell Significance Index: 6.2600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2817
    Cell Significance Index: 18.1800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2701
    Cell Significance Index: 147.5100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2647
    Cell Significance Index: 6.9600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2590
    Cell Significance Index: 114.5200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2561
    Cell Significance Index: 46.1600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2474
    Cell Significance Index: 29.1800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2463
    Cell Significance Index: 88.3300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2441
    Cell Significance Index: 33.5200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2415
    Cell Significance Index: 6.7500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2386
    Cell Significance Index: 45.4100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2182
    Cell Significance Index: 26.8400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2143
    Cell Significance Index: 148.2000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1676
    Cell Significance Index: 21.4900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.0984
    Cell Significance Index: 1.3800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0920
    Cell Significance Index: 5.8000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0869
    Cell Significance Index: 4.0500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0862
    Cell Significance Index: 3.9100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0711
    Cell Significance Index: 5.0300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0389
    Cell Significance Index: 5.0300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0290
    Cell Significance Index: 0.3000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0189
    Cell Significance Index: 0.5400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0141
    Cell Significance Index: 0.4100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0013
    Cell Significance Index: 2.5400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0001
    Cell Significance Index: -0.0700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0016
    Cell Significance Index: -0.0500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0020
    Cell Significance Index: -0.1500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0037
    Cell Significance Index: -0.1000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0084
    Cell Significance Index: -6.3700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0090
    Cell Significance Index: -16.6100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0105
    Cell Significance Index: -16.2200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0121
    Cell Significance Index: -8.8500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0125
    Cell Significance Index: -7.9600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0132
    Cell Significance Index: -0.8900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0238
    Cell Significance Index: -17.6300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0259
    Cell Significance Index: -0.7100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0263
    Cell Significance Index: -0.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0326
    Cell Significance Index: -3.3300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0347
    Cell Significance Index: -19.5700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0376
    Cell Significance Index: -17.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0392
    Cell Significance Index: -24.5100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0470
    Cell Significance Index: -2.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0535
    Cell Significance Index: -9.1300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0544
    Cell Significance Index: -6.2300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0656
    Cell Significance Index: -9.5300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0657
    Cell Significance Index: -2.3100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0741
    Cell Significance Index: -21.3200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0763
    Cell Significance Index: -1.9500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0962
    Cell Significance Index: -5.9100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1019
    Cell Significance Index: -2.1700
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.1021
    Cell Significance Index: -0.8200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1197
    Cell Significance Index: -25.2100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1443
    Cell Significance Index: -11.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1556
    Cell Significance Index: -8.7300
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.1577
    Cell Significance Index: -2.0200
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.1869
    Cell Significance Index: -1.5700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1960
    Cell Significance Index: -20.4100
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.2048
    Cell Significance Index: -3.1100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2159
    Cell Significance Index: -17.1000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2187
    Cell Significance Index: -7.6000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2236
    Cell Significance Index: -3.3700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2280
    Cell Significance Index: -2.1000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2557
    Cell Significance Index: -11.3100
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2637
    Cell Significance Index: -8.3400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2849
    Cell Significance Index: -7.6200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2915
    Cell Significance Index: -17.8700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3104
    Cell Significance Index: -5.3200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3128
    Cell Significance Index: -8.0400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3183
    Cell Significance Index: -12.0600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3334
    Cell Significance Index: -9.8200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4072
    Cell Significance Index: -10.1800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4374
    Cell Significance Index: -13.9300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4413
    Cell Significance Index: -5.2600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4462
    Cell Significance Index: -6.3900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4484
    Cell Significance Index: -14.6800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4566
    Cell Significance Index: -16.0000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.4578
    Cell Significance Index: -6.8600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** USP5 exhibits several distinctive characteristics that set it apart from other deubiquitinating enzymes: 1. **Cysteine-type deubiquitination activity**: USP5's catalytic site is specifically designed to recognize and remove ubiquitin chains from K48 and K6 linkages. 2. **Dual-edged functionality**: USP5 can both positively and negatively regulate ubiquitin-dependent protein catabolic processes, depending on the context and target proteins. 3. **Cellular localization**: USP5 is expressed in various cell types, including immune cells, endothelial cells, and fibroblasts, highlighting its broad tissue distribution. 4. **Regulatory mechanisms**: USP5's activity is modulated by post-translational modifications, such as phosphorylation and ubiquitination, which can either activate or inhibit its enzymatic activity. **Pathways and Functions:** USP5's involvement in multiple cellular processes can be attributed to its ability to regulate various signaling pathways and protein interactions: 1. **Cytosolic and nuclear functions**: USP5 contributes to the regulation of protein degradation, cell signaling, and transcriptional control in the cytosol and nucleus. 2. **Immune response modulation**: USP5 plays a crucial role in regulating immune cell function, including the activation, proliferation, and differentiation of T cells and B cells. 3. **Cellular differentiation**: USP5 is involved in the regulation of cellular differentiation processes, including the development of cardiac muscle and skeletal muscle. 4. **Proteasomal regulation**: USP5 can both positively and negatively regulate proteasomal activity, influencing the degradation of ubiquitinated proteins. **Clinical Significance:** Dysregulation of USP5 has been implicated in various diseases, including: 1. **Autoimmune disorders**: USP5's role in immune cell function and regulation suggests that dysregulation may contribute to autoimmune diseases, such as rheumatoid arthritis and lupus. 2. **Cancer**: USP5's involvement in cellular differentiation and protein degradation may contribute to cancer development and progression. 3. **Neurological disorders**: USP5's regulation of protein degradation and cell signaling may be involved in the pathogenesis of neurodegenerative diseases, such as Alzheimer's and Parkinson's. 4. **Cardiovascular disease**: USP5's role in cardiac muscle differentiation and protein degradation may contribute to the development of cardiovascular disease. In conclusion, USP5 is a complex deubiquitinating enzyme that plays a multifaceted role in regulating protein homeostasis, immune responses, and cellular differentiation. Further research is needed to fully elucidate the mechanisms underlying USP5's functions and to explore its therapeutic potential in various diseases.

Genular Protein ID: 3774223688

Symbol: UBP5_HUMAN

Name: Ubiquitin carboxyl-terminal hydrolase 5

UniProtKB Accession Codes:

P45974 D3DUS7 D3DUS8 Q96J22

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CPTAC 2 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 11 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PIR 1 PIRSF 1 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7498549

Title: cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2).

PubMed ID: 7498549

DOI: 10.1016/0014-5793(95)01287-7

PubMed ID: 8723724

Title: A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.

PubMed ID: 8723724

DOI: 10.1101/gr.6.4.314

PubMed ID: 9074930

Title: Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination.

PubMed ID: 9074930

DOI: 10.1101/gr.7.3.268

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7851534

Title: A human de-ubiquitinating enzyme with both isopeptidase and peptidase activities in vitro.

PubMed ID: 7851534

DOI: 10.1016/0014-5793(94)01451-6

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18482987

Title: Recognition of polyubiquitin isoforms by the multiple ubiquitin binding modules of isopeptidase T.

PubMed ID: 18482987

DOI: 10.1074/jbc.m800947200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19098288

Title: Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53.

PubMed ID: 19098288

DOI: 10.1074/jbc.m805871200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22216260

Title: Domain analysis reveals that a deubiquitinating enzyme USP13 performs non-activating catalysis for Lys63-linked polyubiquitin.

PubMed ID: 22216260

DOI: 10.1371/journal.pone.0029362

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16564012

Title: The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin.

PubMed ID: 16564012

DOI: 10.1016/j.cell.2006.02.038

Sequence Information:

  • Length: 858
  • Mass: 95786
  • Checksum: E99CB7CDFA682C65
  • Sequence:
    • MAELSEEALL SVLPTIRVPK AGDRVHKDEC AFSFDTPESE GGLYICMNTF LGFGKQYVER 
HFNKTGQRVY LHLRRTRRPK EEDPATGTGD PPRKKPTRLA IGVEGGFDLS EEKFELDEDV 
KIVILPDYLE IARDGLGGLP DIVRDRVTSA VEALLSADSA SRKQEVQAWD GEVRQVSKHA 
FSLKQLDNPA RIPPCGWKCS KCDMRENLWL NLTDGSILCG RRYFDGSGGN NHAVEHYRET 
GYPLAVKLGT ITPDGADVYS YDEDDMVLDP SLAEHLSHFG IDMLKMQKTD KTMTELEIDM 
NQRIGEWELI QESGVPLKPL FGPGYTGIRN LGNSCYLNSV VQVLFSIPDF QRKYVDKLEK 
IFQNAPTDPT QDFSTQVAKL GHGLLSGEYS KPVPESGDGE RVPEQKEVQD GIAPRMFKAL 
IGKGHPEFST NRQQDAQEFF LHLINMVERN CRSSENPNEV FRFLVEEKIK CLATEKVKYT 
QRVDYIMQLP VPMDAALNKE ELLEYEEKKR QAEEEKMALP ELVRAQVPFS SCLEAYGAPE 
QVDDFWSTAL QAKSVAVKTT RFASFPDYLV IQIKKFTFGL DWVPKKLDVS IEMPEELDIS 
QLRGTGLQPG EEELPDIAPP LVTPDEPKGS LGFYGNEDED SFCSPHFSSP TSPMLDESVI 
IQLVEMGFPM DACRKAVYYT GNSGAEAAMN WVMSHMDDPD FANPLILPGS SGPGSTSAAA 
DPPPEDCVTT IVSMGFSRDQ ALKALRATNN SLERAVDWIF SHIDDLDAEA AMDISEGRSA 
ADSISESVPV GPKVRDGPGK YQLFAFISHM GTSTMCGHYV CHIKKEGRWV IYNDQKVCAS 
EKPPKDLGYI YFYQRVAS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.