Details for: NPRL3

Gene ID: 8131

Symbol: NPRL3

Ensembl ID: ENSG00000103148

Description: NPR3 like, GATOR1 complex subunit

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 159.5034
    Cell Significance Index: -24.8100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 119.3014
    Cell Significance Index: -30.2600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 68.9834
    Cell Significance Index: -28.0300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 61.4909
    Cell Significance Index: -31.6300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 50.6988
    Cell Significance Index: -34.0200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 29.3953
    Cell Significance Index: -28.0700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.8857
    Cell Significance Index: -29.4500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.6132
    Cell Significance Index: -31.1100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.6542
    Cell Significance Index: -34.1500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.2176
    Cell Significance Index: -25.2400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.6070
    Cell Significance Index: -14.4600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3494
    Cell Significance Index: 267.8000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.2267
    Cell Significance Index: 15.2200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.1200
    Cell Significance Index: 401.7200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.0391
    Cell Significance Index: 29.0400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8575
    Cell Significance Index: 593.0500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8193
    Cell Significance Index: 89.1200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7929
    Cell Significance Index: 128.9700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7404
    Cell Significance Index: 44.4500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6546
    Cell Significance Index: 50.2300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.5173
    Cell Significance Index: 27.1600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4558
    Cell Significance Index: 82.1700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4254
    Cell Significance Index: 26.8100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4097
    Cell Significance Index: 56.2700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3984
    Cell Significance Index: 10.2400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3473
    Cell Significance Index: 24.0200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3452
    Cell Significance Index: 188.5100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3239
    Cell Significance Index: 292.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3197
    Cell Significance Index: 19.6500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3196
    Cell Significance Index: 4.3600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2915
    Cell Significance Index: 8.4000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2601
    Cell Significance Index: 9.8500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2568
    Cell Significance Index: 11.3600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2513
    Cell Significance Index: 30.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2114
    Cell Significance Index: 11.8600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1812
    Cell Significance Index: 2.1600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1644
    Cell Significance Index: 8.5400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1546
    Cell Significance Index: 3.3500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1530
    Cell Significance Index: 67.6600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1280
    Cell Significance Index: 3.2000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1276
    Cell Significance Index: 2.4900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1244
    Cell Significance Index: 8.0300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1177
    Cell Significance Index: 23.6200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1063
    Cell Significance Index: 200.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1055
    Cell Significance Index: 4.9200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1051
    Cell Significance Index: 161.8400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0961
    Cell Significance Index: 9.5100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0950
    Cell Significance Index: 6.3900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0940
    Cell Significance Index: 2.5200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0892
    Cell Significance Index: 164.5000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0802
    Cell Significance Index: 15.2600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0765
    Cell Significance Index: 1.6400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0649
    Cell Significance Index: 88.2500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0452
    Cell Significance Index: 28.7000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0443
    Cell Significance Index: 0.7600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0278
    Cell Significance Index: 3.5700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0113
    Cell Significance Index: 1.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0087
    Cell Significance Index: 3.9700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0113
    Cell Significance Index: -1.3300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0161
    Cell Significance Index: -0.4300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0177
    Cell Significance Index: -13.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0255
    Cell Significance Index: -1.2000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0266
    Cell Significance Index: -3.8600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0305
    Cell Significance Index: -23.1000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0319
    Cell Significance Index: -23.6200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0503
    Cell Significance Index: -28.3800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0544
    Cell Significance Index: -5.5600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0597
    Cell Significance Index: -10.2000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0602
    Cell Significance Index: -37.5900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0647
    Cell Significance Index: -1.7000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0695
    Cell Significance Index: -3.1500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1017
    Cell Significance Index: -29.2500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1102
    Cell Significance Index: -3.0000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1126
    Cell Significance Index: -1.8900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1277
    Cell Significance Index: -2.7200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1288
    Cell Significance Index: -3.0900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1343
    Cell Significance Index: -10.0100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1704
    Cell Significance Index: -19.8600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1704
    Cell Significance Index: -35.8900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1793
    Cell Significance Index: -3.9300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1927
    Cell Significance Index: -10.0400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1963
    Cell Significance Index: -13.8800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2065
    Cell Significance Index: -23.6600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2145
    Cell Significance Index: -4.4500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2180
    Cell Significance Index: -7.6600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2285
    Cell Significance Index: -7.9400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2335
    Cell Significance Index: -7.4800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2488
    Cell Significance Index: -25.9100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2845
    Cell Significance Index: -8.1200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3376
    Cell Significance Index: -26.7400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.3440
    Cell Significance Index: -4.9400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3675
    Cell Significance Index: -5.4300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3938
    Cell Significance Index: -4.9100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4199
    Cell Significance Index: -8.7900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4325
    Cell Significance Index: -11.0500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4389
    Cell Significance Index: -26.9100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.5625
    Cell Significance Index: -7.1000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.5679
    Cell Significance Index: -13.1200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5713
    Cell Significance Index: -11.4700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6244
    Cell Significance Index: -18.3900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NPRL3 is a gene that belongs to the GATOR1 complex, a multiprotein complex that regulates mTORC1 signaling. The NPRL3 protein is a subunit of this complex and is involved in the negative regulation of mTORC1 signaling. This suggests that NPRL3 plays a role in limiting the activity of mTORC1, which is a critical regulator of cell growth, metabolism, and autophagy. NPRL3 is also involved in the regulation of autophagy, a cellular process that involves the degradation and recycling of cellular components. **Pathways and Functions** NPRL3 is involved in several cellular pathways, including: 1. **Autophagy**: NPRL3 plays a role in the regulation of autophagy, a process that involves the degradation and recycling of cellular components. 2. **mTORC1 signaling**: NPRL3 is a subunit of the GATOR1 complex, which regulates mTORC1 signaling. mTORC1 is a key regulator of cell growth, proliferation, and metabolism. 3. **Stress response**: NPRL3 is involved in the regulation of cellular responses to stress, including amino acid starvation and starvation. 4. **Amino acid regulate mTORC1**: NPRL3 is involved in the regulation of mTORC1 signaling in response to amino acids. 5. **GTPase activator activity**: NPRL3 has GTPase activator activity, which suggests that it regulates the activity of GTP-binding proteins. **Clinical Significance** NPRL3 has been implicated in several diseases, including: 1. **Neurodegenerative diseases**: NPRL3 has been shown to be involved in the regulation of autophagy and mTORC1 signaling, which are critical pathways involved in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. 2. **Cancer**: NPRL3 has been implicated in the regulation of cell growth and metabolism, which are critical processes involved in cancer development and progression. 3. **Metabolic disorders**: NPRL3 has been shown to be involved in the regulation of glucose and lipid metabolism, which are critical processes involved in metabolic disorders such as type 2 diabetes and obesity. In conclusion, NPRL3 is a gene that plays a critical role in regulating autophagy, mTORC1 signaling, and stress response. Its dysregulation has been implicated in several diseases, including neurodegenerative diseases, cancer, and metabolic disorders. Further research is needed to fully understand the functions of NPRL3 and its role in human disease.

Genular Protein ID: 2214431057

Symbol: NPRL3_HUMAN

Name: Protein CGTHBA

UniProtKB Accession Codes:

Q12980 D3DU40 Q1W6H0 Q4TT56 Q92469

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 6 Ensembl 1 ExpressionAtlas 1 GO 11 GeneCards 1 GeneReviews 1 GeneTree 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8575760

Title: Conservation of position and sequence of a novel, widely expressed gene containing the major human alpha-globin regulatory element.

PubMed ID: 8575760

DOI: 10.1006/geno.1995.9951

PubMed ID: 16728641

Title: A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter.

PubMed ID: 16728641

DOI: 10.1126/science.1126431

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 19521502

Title: A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex.

PubMed ID: 19521502

DOI: 10.1371/journal.pgen.1000515

PubMed ID: 23723238

Title: A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.

PubMed ID: 23723238

DOI: 10.1126/science.1232044

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28199306

Title: KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

PubMed ID: 28199306

DOI: 10.1038/nature21423

PubMed ID: 36007018

Title: Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1.

PubMed ID: 36007018

DOI: 10.1126/science.abg6621

PubMed ID: 29590090

Title: Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.

PubMed ID: 29590090

DOI: 10.1038/nature26158

PubMed ID: 35338845

Title: Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.

PubMed ID: 35338845

DOI: 10.1016/j.molcel.2022.03.002

PubMed ID: 26505888

Title: Mutations in the mammalian target of rapamycin pathway regulators NPRL2 and NPRL3 cause focal epilepsy.

PubMed ID: 26505888

DOI: 10.1002/ana.24547

PubMed ID: 26285051

Title: Familial cortical dysplasia caused by mutation in the mammalian target of rapamycin regulator NPRL3.

PubMed ID: 26285051

DOI: 10.1002/ana.24502

PubMed ID: 27173016

Title: Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia.

PubMed ID: 27173016

DOI: 10.1111/epi.13391

Sequence Information:

  • Length: 569
  • Mass: 63605
  • Checksum: 44BEF42AA7F2841D
  • Sequence:
    • MRDNTSPISV ILVSSGSRGN KLLFRYPFQR SQEHPASQTS KPRSRYAASN TGDHADEQDG 
DSRFSDVILA TILATKSEMC GQKFELKIDN VRFVGHPTLL QHALGQISKT DPSPKREAPT 
MILFNVVFAL RANADPSVIN CLHNLSRRIA TVLQHEERRC QYLTREAKLI LALQDEVSAM 
ADGNEGPQSP FHHILPKCKL ARDLKEAYDS LCTSGVVRLH INSWLEVSFC LPHKIHYAAS 
SLIPPEAIER SLKAIRPYHA LLLLSDEKSL LGELPIDCSP ALVRVIKTTS AVKNLQQLAQ 
DADLALLQVF QLAAHLVYWG KAIIIYPLCE NNVYMLSPNA SVCLYSPLAE QFSHQFPSHD 
LPSVLAKFSL PVSLSEFRNP LAPAVQETQL IQMVVWMLQR RLLIQLHTYV CLMASPSEEE 
PRPREDDVPF TARVGGRSLS TPNALSFGSP TSSDDMTLTS PSMDNSSAEL LPSGDSPLNQ 
RMTENLLASL SEHERAAILS VPAAQNPEDL RMFARLLHYF RGRHHLEEIM YNENTRRSQL 
LMLFDKFRSV LVVTTHEDPV IAVFQALLP

Genular Protein ID: 538858576

Symbol: B7Z6Q0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z6Q0

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 2 GO 4 GeneTree 1 HGNC 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 2 RuleBase 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 544
  • Mass: 60792
  • Checksum: C6A12CEBC88DA304
  • Sequence:
    • MRDNTSPISV ILVSSGSRGN KLLFRYPFQR SQEHPASQTS KPRSRYAASN TGDHADEQDG 
DSRFSDVILA TILATKSEMC GQKFELKIDN VRFVGHPTLL QHALGQANAD PSVINCLHNL 
SRRIATVLQH EERRCQYLTR EAKLILALQD EVSAMADGNE GPQSPFHHIL PKCKLARDLK 
EAYDSLCTSG VVRLHINSWL EVSFCLPHKI HYAASSLIPP EAIERSLKAI RPYHALLLLS 
DEKSLLGELP IDCSPALVRV IKTTSAVKNL QQLAQDADLA LLQVFQLAAH LVYWGKAIII 
YPLCENNVYM LSPNASVCLY SPLAEQFSHQ FPSHDLPSVL AKFSLPVSLS EFRNPLAPAV 
QETQLIQMVV WMLQRRLLIQ LHTYVCLMAS PSEEEPRPRE DDVPFTARVG GRSLSTPNAL 
SFGSPTSSDD MTLTSPSMDN SSAELLPSGD SPLNQRMTEN LLASLSEHER AAILSVPAAQ 
NPEDLRMFAR LLHYFRGRHH LEEIMYNENT RRSQLLMLFD KFRSVLVVTT HEDPVIAVFQ 
ALLP

Genular Protein ID: 1914215432

Symbol: Q9BTE2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9BTE2

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 7 GO 6 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 2 RuleBase 1 SAM 1 iPTMnet 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 390
  • Mass: 43606
  • Checksum: C0FF9F9EF59A63F2
  • Sequence:
    • MADGNEGPQS PFHHILPKCK LARDLKEAYD SLCTSGVVRL HINSWLEVSF CLPHKIHYAA 
SSLIPPEAIE RSLKAIRPYH ALLLLSDEKS LLGELPIDCS PALVRVIKTT SAVKNLQQLA 
QDADLALLQV FQLAAHLVYW GKAIIIYPLC ENNVYMLSPN ASVCLYSPLA EQFSHQFPSH 
DLPSVLAKFS LPVSLSEFRN PLAPAVQETQ LIQMVVWMLQ RRLLIQLHTY VCLMASPSEE 
EPRPREDDVP FTARVGGRSL STPNALSFGS PTSSDDMTLT SPSMDNSSAE LLPSGDSPLN 
QRMTENLLAS LSEHERAAIL SVPAAQNPED LRMFARLLHY FRGRHHLEEI MYNENTRRSQ 
LLMLFDKFRS VLVVTTHEDP VIAVFQALLP

Genular Protein ID: 3194030851

Symbol: B7Z220_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z220

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SAM 1

Sequence Information:

  • Length: 491
  • Mass: 55025
  • Checksum: BC7CA4E9B4C0FAE7
  • Sequence:
    • MCGQKFELEI DNVRFVGHPT LLQHALGQIS KTDPSPKREA PTMILFNVVF ALRANADPSV 
INCLHNLSRR IATVLQHEER RCQYLTREAK LILALQDEVS AMADGNEGPQ SPFHHILPKC 
KLARDLKEAY DSLCTSGVVR LHINSWLEVS FCLPHKIHYA ASSLIPPEAI ERSLKAIRPY 
HALLLLSDEK SLLGELPIDC SPALVRVIKT TSAVKNLQQL AQDADLALLQ VFQLAAHLVY 
WGKAIIIYPL CENNVYMLSP NASVCLYSPL AEQFSHQFPS HDLPSVLAKF SLPVSLSEFR 
NPLAPAVQET QLIQMVVWML QRRLLIQLHT YVCLMASPSE EEPRPREDDV PFTARVGGRS 
LSTPNALSFG SPTSSDDMTL TSPSMDNSSA ELLPSGDSPL NQRMTENLLA SLSEHERAAI 
LSVPAAQNPE DLRMFARLLH YFRGRHHLEE IMYNENTRRS QLLMLFDKFR SVLVVTTHED 
PVIAVFQALL P

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.