Details for: FZD6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 149.2813
Cell Significance Index: -23.2200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 91.1122
Cell Significance Index: -23.1100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 44.6146
Cell Significance Index: -18.1300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 18.9869
Cell Significance Index: -23.4100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 18.8218
Cell Significance Index: -17.9700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.7297
Cell Significance Index: -12.5400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.4442
Cell Significance Index: 465.1500 - Cell Name: endocardial cell (CL0002350)
Fold Change: 1.7920
Cell Significance Index: 10.5800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.5437
Cell Significance Index: 80.1900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.0175
Cell Significance Index: 27.2700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9556
Cell Significance Index: 862.8200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.8505
Cell Significance Index: 104.5800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.8004
Cell Significance Index: 41.6900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.6807
Cell Significance Index: 122.7200 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.6720
Cell Significance Index: 366.9800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6563
Cell Significance Index: 71.3900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6530
Cell Significance Index: 106.2100 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.6525
Cell Significance Index: 9.3900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.6012
Cell Significance Index: 6.8300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5587
Cell Significance Index: 33.5400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5466
Cell Significance Index: 241.6500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.5378
Cell Significance Index: 15.0300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.5118
Cell Significance Index: 13.9300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4901
Cell Significance Index: 97.2600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4805
Cell Significance Index: 96.3800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.4417
Cell Significance Index: 31.2400 - Cell Name: peg cell (CL4033014)
Fold Change: 0.3255
Cell Significance Index: 7.5200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2559
Cell Significance Index: 11.9300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2537
Cell Significance Index: 7.3100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.2502
Cell Significance Index: 6.6800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2488
Cell Significance Index: 5.3900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2230
Cell Significance Index: 10.1100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1713
Cell Significance Index: 16.9500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1546
Cell Significance Index: 11.8600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1500
Cell Significance Index: 10.3700 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1327
Cell Significance Index: 2.5900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1074
Cell Significance Index: 202.2800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.1070
Cell Significance Index: 5.4100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1003
Cell Significance Index: 45.5100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0929
Cell Significance Index: 33.3100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0639
Cell Significance Index: 40.5900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0326
Cell Significance Index: 22.5700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0303
Cell Significance Index: 46.5700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0170
Cell Significance Index: 23.1500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0107
Cell Significance Index: 19.7800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0046
Cell Significance Index: 0.1600 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.0033
Cell Significance Index: 0.0200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0010
Cell Significance Index: 0.1800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0102
Cell Significance Index: -7.5100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0177
Cell Significance Index: -13.4300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0188
Cell Significance Index: -1.4000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0192
Cell Significance Index: -2.4800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0212
Cell Significance Index: -15.7100 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0308
Cell Significance Index: -3.9500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0314
Cell Significance Index: -17.6900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0412
Cell Significance Index: -25.7500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0447
Cell Significance Index: -2.8200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0482
Cell Significance Index: -13.8700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0594
Cell Significance Index: -0.8100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0662
Cell Significance Index: -9.6300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0671
Cell Significance Index: -1.4300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0678
Cell Significance Index: -7.9100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0730
Cell Significance Index: -4.4900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0781
Cell Significance Index: -4.3800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0937
Cell Significance Index: -10.7300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0999
Cell Significance Index: -13.7200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1037
Cell Significance Index: -10.6000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1044
Cell Significance Index: -2.6100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1136
Cell Significance Index: -3.6400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1143
Cell Significance Index: -24.0800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1164
Cell Significance Index: -5.4700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1167
Cell Significance Index: -3.0000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1200
Cell Significance Index: -12.4900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.1439
Cell Significance Index: -1.3300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1570
Cell Significance Index: -18.5100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2484
Cell Significance Index: -16.7000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2500
Cell Significance Index: -19.8000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2781
Cell Significance Index: -17.0500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3309
Cell Significance Index: -21.3500 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.3372
Cell Significance Index: -4.8000 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.3466
Cell Significance Index: -7.1900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.3639
Cell Significance Index: -13.7800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3737
Cell Significance Index: -12.9900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3938
Cell Significance Index: -17.4200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.4000
Cell Significance Index: -8.5500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.4083
Cell Significance Index: -7.2200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.4114
Cell Significance Index: -6.2000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4470
Cell Significance Index: -14.2400 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.4610
Cell Significance Index: -6.5500 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.4619
Cell Significance Index: -11.8000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4685
Cell Significance Index: -24.6000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.4748
Cell Significance Index: -7.0100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4943
Cell Significance Index: -18.1500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4947
Cell Significance Index: -17.3300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5140
Cell Significance Index: -16.8300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.5184
Cell Significance Index: -14.8600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5342
Cell Significance Index: -15.6900 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.5673
Cell Significance Index: -7.6500 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.5747
Cell Significance Index: -13.9200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5888
Cell Significance Index: -10.0900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 311801858
Symbol: FZD6_HUMAN
Name: Frizzled-6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9480858
PubMed ID: 11707601
Title: BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.
PubMed ID: 11707601
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 22045688
Title: FZD6 is a novel gene for human neural tube defects.
PubMed ID: 22045688
DOI: 10.1002/humu.21643
PubMed ID: 22575959
Title: ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
PubMed ID: 22575959
DOI: 10.1038/nature11019
PubMed ID: 21665003
Title: Mutations in Frizzled 6 cause isolated autosomal-recessive nail dysplasia.
PubMed ID: 21665003
Sequence Information:
- Length: 706
- Mass: 79292
- Checksum: FBFF5844D6AB0223
- Sequence:
MEMFTFLLTC IFLPLLRGHS LFTCEPITVP RCMKMAYNMT FFPNLMGHYD QSIAAVEMEH FLPLANLECS PNIETFLCKA FVPTCIEQIH VVPPCRKLCE KVYSDCKKLI DTFGIRWPEE LECDRLQYCD ETVPVTFDPH TEFLGPQKKT EQVQRDIGFW CPRHLKTSGG QGYKFLGIDQ CAPPCPNMYF KSDELEFAKS FIGTVSIFCL CATLFTFLTF LIDVRRFRYP ERPIIYYSVC YSIVSLMYFI GFLLGDSTAC NKADEKLELG DTVVLGSQNK ACTVLFMLLY FFTMAGTVWW VILTITWFLA AGRKWSCEAI EQKAVWFHAV AWGTPGFLTV MLLAMNKVEG DNISGVCFVG LYDLDASRYF VLLPLCLCVF VGLSLLLAGI ISLNHVRQVI QHDGRNQEKL KKFMIRIGVF SGLYLVPLVT LLGCYVYEQV NRITWEITWV SDHCRQYHIP CPYQAKAKAR PELALFMIKY LMTLIVGISA VFWVGSKKTC TEWAGFFKRN RKRDPISESR RVLQESCEFF LKHNSKVKHK KKHYKPSSHK LKVISKSMGT STGATANHGT SAVAITSHDY LGQETLTEIQ TSPETSMREV KADGASTPRL REQDCGEPAS PAASISRLSG EQVDGKGQAG SVSESARSEG RISPKSDITD TGLAQSNNLQ VPSSSEPSSL KGSTSLLVHP VSGVRKEQGG GCHSDT
Genular Protein ID: 3143662425
Symbol: B4E236_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 651
- Mass: 72870
- Checksum: 213E64F38DACAE4E
- Sequence:
MLAQHFLPLA NLECSPNIET FLCKAFVPTC IEQIHVVPPC RKLCEKVYSD CKKLIDTFGI RWPEELECDR LQYCDETVPV TFDPHTEFLG PQKKTEQVQR DIGFWCPRHL KTSGGQGYKF LGIDQCAPPC PNMYFKSDEL EFAKSFIGTV SIFCLCATLF TFLTFLIDVR RFRYPERPII YYSVCYSIVS LMYFIGFLLG DSTACNKADE KLELGDTVVL GSQNKACTVL FMLLYFFTMA GTVWWVILTI TWFLAAGRKW SCEAIEQKAV WFHAVAWGTP GFLTVMLLAM NKVEGDNISG VCFVGLYDLD ASRYFVLLPL CLCVFVGLSL LLAGIISLNH VRQVIQHDGR NQEKLKKFMI RIGVFSGLYL VPLVTLLGCY VYEQVNRITW EITWVSDHCR QYHIPCPYQA KAKARPELAL FMIKYLMTLI VGISAVFWVG SKKTCTEWAG FFKRNRKRDP ISESRRVLQE SCEFFLKHNS KVKHKKKHYK PSSHKLKVIS KSMGTSTGAT ANHGTSAVAI TSHDYLGQET LTEIQTSPET SMREVKADGA STPRLREQDC GEPASPAASI SRLSGEQVDG KGQAGSVSES ARSEGRISPK SDITDTGLAQ SNNLQVPSSS EPSSLKGSTS LLVHPVSGVR KEQGGGCHSD T
Genular Protein ID: 1840197582
Symbol: B4DL33_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 401
- Mass: 44287
- Checksum: B5CF3EEAE9E1706B
- Sequence:
MTRVLPRWKW SCEAIEQKAV WFHAVAWGTP GFLTVMLLAL NKVEGDNISG VCFVGLYDLD ASRYFVLLPL CLCVFVGLSL LLAGIISLNH VRQVIQHDGR NQEKLKKFMI RIGVFSGLYL VPLVTLLGCY VYEQVNRITW EITWVSDHCR QYHIPCPYQA KAKARPELAL FMIKYLMTLI VGISAVFWVG SKKTCTEWAG FFKRNRKRDP ISESRRVLQE SCEFFLKHNS KVKHKKKHYK PSSHKLKVIS KSMGTSTGAT ANHGTSAVAI TSHDYLGQET LTEIQTSPET SMREVKADGA STPRLREQDC GEPASPAASI SRLSGEQVDG KGQAGSVSES ARSEGRISPK SDITDTGLAQ SNNLQVPSSS EPSSLKGSTS LLVHPVSGVR KEQGGGCHSD T
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.