Details for: PLA2G6

Gene ID: 8398

Symbol: PLA2G6

Ensembl ID: ENSG00000184381

Description: phospholipase A2 group VI

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 78.3695
    Cell Significance Index: -12.1900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 47.4682
    Cell Significance Index: -12.0400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 29.0179
    Cell Significance Index: -13.7000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 27.4580
    Cell Significance Index: -11.1600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 11.6785
    Cell Significance Index: -11.1500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.2680
    Cell Significance Index: -12.6600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.7744
    Cell Significance Index: -12.7900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.2564
    Cell Significance Index: -12.8500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.0796
    Cell Significance Index: -6.7400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.2196
    Cell Significance Index: 120.6500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 1.0991
    Cell Significance Index: 15.7400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0309
    Cell Significance Index: 930.7800
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.9212
    Cell Significance Index: 4.0100
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.7561
    Cell Significance Index: 12.4600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7174
    Cell Significance Index: 78.0400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.6966
    Cell Significance Index: 18.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.6800
    Cell Significance Index: 98.8400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6612
    Cell Significance Index: 107.5300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6576
    Cell Significance Index: 39.4800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6142
    Cell Significance Index: 8.3800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4408
    Cell Significance Index: 9.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4007
    Cell Significance Index: 11.5500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3917
    Cell Significance Index: 27.0900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3713
    Cell Significance Index: 16.8300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3414
    Cell Significance Index: 9.5400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3046
    Cell Significance Index: 61.1100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2900
    Cell Significance Index: 57.5600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2033
    Cell Significance Index: 23.6900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1566
    Cell Significance Index: 56.1800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1404
    Cell Significance Index: 7.3700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1382
    Cell Significance Index: 7.1800
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.1366
    Cell Significance Index: 1.7200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1345
    Cell Significance Index: 93.0300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.1246
    Cell Significance Index: 1.5500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1135
    Cell Significance Index: 5.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0952
    Cell Significance Index: 179.2200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0892
    Cell Significance Index: 1.8500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0857
    Cell Significance Index: 3.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0743
    Cell Significance Index: 114.3700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0715
    Cell Significance Index: 13.6000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0711
    Cell Significance Index: 38.8400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0699
    Cell Significance Index: 30.8900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0591
    Cell Significance Index: 10.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0567
    Cell Significance Index: 36.0000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0511
    Cell Significance Index: 3.9300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0455
    Cell Significance Index: 0.9700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0401
    Cell Significance Index: 2.5900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0383
    Cell Significance Index: 4.7100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0361
    Cell Significance Index: 66.5000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0355
    Cell Significance Index: 48.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0352
    Cell Significance Index: 2.2200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0300
    Cell Significance Index: 2.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0166
    Cell Significance Index: 2.2800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0093
    Cell Significance Index: 1.1000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0019
    Cell Significance Index: 0.0500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0016
    Cell Significance Index: 0.7200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0008
    Cell Significance Index: 0.1000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0007
    Cell Significance Index: -0.0400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0070
    Cell Significance Index: -0.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0116
    Cell Significance Index: -8.5300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0154
    Cell Significance Index: -11.6400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0156
    Cell Significance Index: -11.5500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0174
    Cell Significance Index: -0.7700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0223
    Cell Significance Index: -12.5700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0239
    Cell Significance Index: -14.9300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0279
    Cell Significance Index: -1.3100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0335
    Cell Significance Index: -1.2700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0346
    Cell Significance Index: -5.9100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0377
    Cell Significance Index: -10.8500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0460
    Cell Significance Index: -4.7000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0460
    Cell Significance Index: -1.1500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0462
    Cell Significance Index: -3.2700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0489
    Cell Significance Index: -1.3300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0498
    Cell Significance Index: -5.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0574
    Cell Significance Index: -7.4100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0689
    Cell Significance Index: -14.5100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0706
    Cell Significance Index: -4.3400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0778
    Cell Significance Index: -2.0000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0789
    Cell Significance Index: -4.1100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0821
    Cell Significance Index: -6.1200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0974
    Cell Significance Index: -10.1400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1202
    Cell Significance Index: -3.1600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.1316
    Cell Significance Index: -3.2100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1535
    Cell Significance Index: -12.1600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1556
    Cell Significance Index: -3.3300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1691
    Cell Significance Index: -1.7500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1714
    Cell Significance Index: -5.4900
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -0.1788
    Cell Significance Index: -3.7300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1829
    Cell Significance Index: -3.5700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1928
    Cell Significance Index: -2.9100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1948
    Cell Significance Index: -4.5000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2067
    Cell Significance Index: -12.6700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2076
    Cell Significance Index: -5.9300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2090
    Cell Significance Index: -1.9300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2281
    Cell Significance Index: -7.2700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2379
    Cell Significance Index: -1.9400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2558
    Cell Significance Index: -8.9600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2562
    Cell Significance Index: -5.6100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2593
    Cell Significance Index: -8.4900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2613
    Cell Significance Index: -9.0800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Calcium-independent activity**: PLA2G6 is distinguished from other phospholipase A2 enzymes by its calcium-independent activity, allowing it to hydrolyze phospholipids in the absence of calcium ions. 2. **Lysophospholipase activity**: PLA2G6 exhibits lysophospholipase activity, which is essential for the production of bioactive lysophospholipids, such as lysophosphatidic acid (LPA) and lysophosphatidylcholine (LPC). 3. **Expression in various cell types**: PLA2G6 is expressed in multiple cell types, including kidney capillary endothelial cells, mononuclear cells, and cardiac muscle myoblasts, highlighting its broad tissue distribution. **Pathways and Functions:** 1. **Lipid metabolism**: PLA2G6 is involved in the hydrolysis of phospholipids, leading to the production of lysophospholipids, which play crucial roles in lipid signaling pathways. 2. **Immune response**: PLA2G6 is implicated in the regulation of immune responses, including phagocytosis, chemotaxis, and cytokine production, through its interaction with pattern recognition receptors and other immune cells. 3. **Cellular signaling**: PLA2G6 is involved in various cellular signaling pathways, including the regulation of insulin secretion, platelet activation, and ceramide biosynthesis. 4. **Golgi-to-ER retrograde transport**: PLA2G6 has been shown to participate in the Golgi-to-ER retrograde transport, which is essential for the regulation of lipid metabolism and cellular homeostasis. **Clinical Significance:** 1. **Innate immune disorders**: PLA2G6 has been associated with various innate immune disorders, including primary immunodeficiency diseases, such as chronic granulomatous disease and Wiskott-Aldrich syndrome. 2. **Autoimmune diseases**: PLA2G6 has been implicated in the pathogenesis of autoimmune diseases, including rheumatoid arthritis, lupus, and multiple sclerosis, through its role in lipid metabolism and immune response regulation. 3. **Cancer**: PLA2G6 has been shown to play a role in cancer progression and metastasis, particularly in the regulation of lipid metabolism and cell signaling pathways. In conclusion, PLA2G6 is a multifunctional enzyme that plays a critical role in lipid metabolism, immune response, and cellular signaling. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the mechanisms underlying PLA2G6 function and its clinical significance.

Genular Protein ID: 2171686395

Symbol: PLPL9_HUMAN

Name: 85/88 kDa calcium-independent phospholipase A2

UniProtKB Accession Codes:

O60733 A8K597 B0QYE8 O75645 Q8N452 Q9UG29 Q9UIT0 Q9Y671

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 95 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 3 EMBL 44 Ensembl 6 ExpressionAtlas 1 GO 27 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 5 RefSeq 10 Rhea 38 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9417066

Title: Multiple splice variants of the human calcium-independent phospholipase A2 and their effect on enzyme activity.

PubMed ID: 9417066

DOI: 10.1074/jbc.273.1.207

PubMed ID: 10092647

Title: Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A2 (iPLA2) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA2 gene on chromosome 22q13.1.

PubMed ID: 10092647

DOI: 10.1074/jbc.274.14.9607

PubMed ID: 10336645

Title: The human calcium-independent phospholipase A2 gene. Multiple enzymes with distinct properties from a single gene.

PubMed ID: 10336645

DOI: 10.1046/j.1432-1327.1999.00418.x

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18208975

Title: iPLA2beta: front and center in human monocyte chemotaxis to MCP-1.

PubMed ID: 18208975

DOI: 10.1084/jem.20071243

PubMed ID: 19029121

Title: Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions.

PubMed ID: 19029121

DOI: 10.1194/jlr.r800082-jlr200

PubMed ID: 19164547

Title: Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome.

PubMed ID: 19164547

DOI: 10.1073/pnas.0811224106

PubMed ID: 20886109

Title: Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism.

PubMed ID: 20886109

DOI: 10.1371/journal.pone.0012897

PubMed ID: 23533611

Title: Assessing phospholipase A2 activity toward cardiolipin by mass spectrometry.

PubMed ID: 23533611

DOI: 10.1371/journal.pone.0059267

PubMed ID: 17033970

Title: PLA2G6 mutation underlies infantile neuroaxonal dystrophy.

PubMed ID: 17033970

DOI: 10.1086/508572

PubMed ID: 16783378

Title: PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron.

PubMed ID: 16783378

DOI: 10.1038/ng1826

PubMed ID: 18570303

Title: Characterization of PLA2G6 as a locus for dystonia-parkinsonism.

PubMed ID: 18570303

DOI: 10.1002/ana.21415

PubMed ID: 23749988

Title: Recessive truncating NALCN mutation in infantile neuroaxonal dystrophy with facial dysmorphism.

PubMed ID: 23749988

DOI: 10.1136/jmedgenet-2013-101634

PubMed ID: 28887846

Title: Mutations in KARS cause early-onset hearing loss and leukoencephalopathy: Potential pathogenic mechanism.

PubMed ID: 28887846

DOI: 10.1002/humu.23335

Sequence Information:

  • Length: 806
  • Mass: 89903
  • Checksum: 8E55CD4EB9ACAD8B
  • Sequence:
    • MQFFGRLVNT FSGVTNLFSN PFRVKEVAVA DYTSSDRVRE EGQLILFQNT PNRTWDCVLV 
NPRNSQSGFR LFQLELEADA LVNFHQYSSQ LLPFYESSPQ VLHTEVLQHL TDLIRNHPSW 
SVAHLAVELG IRECFHHSRI ISCANCAENE EGCTPLHLAC RKGDGEILVE LVQYCHTQMD 
VTDYKGETVF HYAVQGDNSQ VLQLLGRNAV AGLNQVNNQG LTPLHLACQL GKQEMVRVLL 
LCNARCNIMG PNGYPIHSAM KFSQKGCAEM IISMDSSQIH SKDPRYGASP LHWAKNAEMA 
RMLLKRGCNV NSTSSAGNTA LHVAVMRNRF DCAIVLLTHG ANADARGEHG NTPLHLAMSK 
DNVEMIKALI VFGAEVDTPN DFGETPTFLA SKIGRLVTRK AILTLLRTVG AEYCFPPIHG 
VPAEQGSAAP HHPFSLERAQ PPPISLNNLE LQDLMHISRA RKPAFILGSM RDEKRTHDHL 
LCLDGGGVKG LIIIQLLIAI EKASGVATKD LFDWVAGTST GGILALAILH SKSMAYMRGM 
YFRMKDEVFR GSRPYESGPL EEFLKREFGE HTKMTDVRKP KVMLTGTLSD RQPAELHLFR 
NYDAPETVRE PRFNQNVNLR PPAQPSDQLV WRAARSSGAA PTYFRPNGRF LDGGLLANNP 
TLDAMTEIHE YNQDLIRKGQ ANKVKKLSIV VSLGTGRSPQ VPVTCVDVFR PSNPWELAKT 
VFGAKELGKM VVDCCTDPDG RAVDRARAWC EMVGIQYFRL NPQLGTDIML DEVSDTVLVN 
ALWETEVYIY EHREEFQKLI QLLLSP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.