Details for: EEA1

Gene ID: 8411

Symbol: EEA1

Ensembl ID: ENSG00000102189

Description: early endosome antigen 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 464.5594
    Cell Significance Index: -72.2600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 274.2433
    Cell Significance Index: -69.5600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 154.4090
    Cell Significance Index: -72.9000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 137.9176
    Cell Significance Index: -56.0300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 128.4057
    Cell Significance Index: -66.0500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 108.7595
    Cell Significance Index: -72.9800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 59.3290
    Cell Significance Index: -73.1500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 59.2306
    Cell Significance Index: -56.5500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 25.0778
    Cell Significance Index: -67.1800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.5603
    Cell Significance Index: -73.2400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.2361
    Cell Significance Index: -52.9400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.9783
    Cell Significance Index: -34.9700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 4.3833
    Cell Significance Index: 117.0400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.9764
    Cell Significance Index: 58.0900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.3088
    Cell Significance Index: 458.1800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.1030
    Cell Significance Index: 161.3800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.8685
    Cell Significance Index: 48.0300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.8110
    Cell Significance Index: 50.6100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.8099
    Cell Significance Index: 363.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.2209
    Cell Significance Index: 63.4200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.2100
    Cell Significance Index: 74.3700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2022
    Cell Significance Index: 431.2300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.0861
    Cell Significance Index: 27.1500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.0091
    Cell Significance Index: 52.5600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9710
    Cell Significance Index: 671.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9454
    Cell Significance Index: 53.0500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9364
    Cell Significance Index: 128.5900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9045
    Cell Significance Index: 111.2200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.9044
    Cell Significance Index: 163.0400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7046
    Cell Significance Index: 31.9400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5097
    Cell Significance Index: 225.3300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5031
    Cell Significance Index: 14.5000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4845
    Cell Significance Index: 33.5100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4177
    Cell Significance Index: 9.0500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3392
    Cell Significance Index: 43.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.3333
    Cell Significance Index: 208.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3324
    Cell Significance Index: 181.5100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3139
    Cell Significance Index: 199.3800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3001
    Cell Significance Index: 13.9900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2853
    Cell Significance Index: 54.2900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.2819
    Cell Significance Index: 6.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2776
    Cell Significance Index: 522.7600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2717
    Cell Significance Index: 26.8800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2558
    Cell Significance Index: 347.8400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2340
    Cell Significance Index: 2.1600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.2327
    Cell Significance Index: 5.5800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2319
    Cell Significance Index: 356.9300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2155
    Cell Significance Index: 97.8000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2027
    Cell Significance Index: 373.7400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1641
    Cell Significance Index: 26.6900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1284
    Cell Significance Index: 2.2000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1245
    Cell Significance Index: 3.5700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.1217
    Cell Significance Index: 1.5100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0181
    Cell Significance Index: 0.8500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0158
    Cell Significance Index: 11.6000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: -0.0009
    Cell Significance Index: -0.7800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0321
    Cell Significance Index: -23.8100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0342
    Cell Significance Index: -5.8400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0508
    Cell Significance Index: -6.5700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0596
    Cell Significance Index: -33.6000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0698
    Cell Significance Index: -4.9400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0762
    Cell Significance Index: -57.6800
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.1136
    Cell Significance Index: -1.4300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1465
    Cell Significance Index: -14.9600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1571
    Cell Significance Index: -18.5300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1579
    Cell Significance Index: -10.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1818
    Cell Significance Index: -9.5500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1934
    Cell Significance Index: -40.7300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2002
    Cell Significance Index: -13.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2031
    Cell Significance Index: -29.5200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2057
    Cell Significance Index: -59.2000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2147
    Cell Significance Index: -25.0200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3057
    Cell Significance Index: -35.0200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3207
    Cell Significance Index: -8.7300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3332
    Cell Significance Index: -8.1300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3472
    Cell Significance Index: -12.2000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3972
    Cell Significance Index: -8.4600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4073
    Cell Significance Index: -4.8600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4081
    Cell Significance Index: -6.0300
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.4450
    Cell Significance Index: -6.4000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4488
    Cell Significance Index: -33.4500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4504
    Cell Significance Index: -46.9000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5023
    Cell Significance Index: -13.4600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5072
    Cell Significance Index: -31.9700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5168
    Cell Significance Index: -22.8600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5548
    Cell Significance Index: -7.5700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.6096
    Cell Significance Index: -69.5900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6124
    Cell Significance Index: -48.5100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6180
    Cell Significance Index: -10.4100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6563
    Cell Significance Index: -21.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6634
    Cell Significance Index: -25.1200
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.7214
    Cell Significance Index: -10.3600
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.7309
    Cell Significance Index: -5.9600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8237
    Cell Significance Index: -50.5000
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.8671
    Cell Significance Index: -13.1700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.0001
    Cell Significance Index: -50.5400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.0014
    Cell Significance Index: -6.0500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.0413
    Cell Significance Index: -22.8000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -1.0794
    Cell Significance Index: -18.0700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.2234
    Cell Significance Index: -25.9700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EEA1 is a membrane-associated protein that belongs to the EEA1 protein family. It is characterized by its ability to bind to phosphatidylinositol, which is a phospholipid component of cell membranes. This binding allows EEA1 to regulate membrane trafficking and fusion events, including the fusion of synaptic vesicles with early endosomes. EEA1 also exhibits homodimerization activity, which enables it to interact with other proteins and regulate signaling pathways. Furthermore, EEA1 has been shown to interact with various proteins, including calmodulin, which is a calcium-binding protein that regulates a wide range of cellular processes. **Pathways and Functions:** EEA1 is involved in several signaling pathways that regulate cellular processes, including: 1. **Endocytosis:** EEA1 plays a crucial role in regulating the internalization of molecules through endocytosis, a process by which cells take in molecules from outside the cell. 2. **Exocytosis:** EEA1 also regulates the release of molecules from the cell through exocytosis, a process by which cells release molecules to the outside. 3. **Immune system:** EEA1 is expressed in immune cells, including dendritic cells and B cells, and plays a role in regulating the activation and function of these cells. 4. **Neurotransmission:** EEA1 is expressed in neurons and plays a role in regulating neurotransmission, including the fusion of synaptic vesicles with early endosomes. 5. **Viral infection:** EEA1 has been shown to interact with viral proteins, including those of influenza and HIV, and regulates viral replication and release. **Clinical Significance:** EEA1 has been implicated in several clinical disorders, including: 1. **Immune system disorders:** EEA1 has been shown to play a role in regulating the function of immune cells, including dendritic cells and B cells, which are involved in autoimmune disorders such as multiple sclerosis and rheumatoid arthritis. 2. **Cancer:** EEA1 has been shown to be overexpressed in several types of cancer, including breast cancer and lung cancer, and may play a role in regulating tumor growth and metastasis. 3. **Neurodegenerative disorders:** EEA1 has been shown to be involved in regulating neurotransmission and may play a role in neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. 4. **Viral infections:** EEA1 has been shown to interact with viral proteins and may play a role in regulating viral replication and release. In conclusion, EEA1 is a critical component of the early endosomal system, playing a key role in regulating cellular processes, including endocytosis, exocytosis, and immune system function. Its clinical significance is evident in its role in regulating immune system disorders, cancer, neurodegenerative disorders, and viral infections. Further research is needed to fully understand the mechanisms by which EEA1 regulates these processes and to explore its potential as a therapeutic target.

Genular Protein ID: 2624685404

Symbol: EEA1_HUMAN

Name: Early endosome antigen 1

UniProtKB Accession Codes:

Q15075 Q14221

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 8 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7768953

Title: EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine 'fingers' and contains a calmodulin-binding IQ motif.

PubMed ID: 7768953

DOI: 10.1074/jbc.270.22.13503

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 9697774

Title: EEA1 links PI(3)K function to Rab5 regulation of endosome fusion.

PubMed ID: 9697774

DOI: 10.1038/28879

PubMed ID: 10491193

Title: Direct interaction of EEA1 with Rab5b.

PubMed ID: 10491193

DOI: 10.1046/j.1432-1327.1999.00743.x

PubMed ID: 10506127

Title: The Rab5 effector EEA1 interacts directly with syntaxin-6.

PubMed ID: 10506127

DOI: 10.1074/jbc.274.41.28857

PubMed ID: 10394369

Title: Phosphatidylinositol 3-phosphate recognition by the FYVE domain.

PubMed ID: 10394369

DOI: 10.1016/s1097-2765(01)80013-7

PubMed ID: 10807926

Title: Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues.

PubMed ID: 10807926

DOI: 10.1074/jbc.m906554199

PubMed ID: 11870209

Title: The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking.

PubMed ID: 11870209

DOI: 10.1242/jcs.115.5.899

PubMed ID: 12493736

Title: Determinants of Rab5 interaction with the N-terminus of early endosome antigen 1.

PubMed ID: 12493736

DOI: 10.1074/jbc.m211514200

PubMed ID: 16314522

Title: Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor.

PubMed ID: 16314522

DOI: 10.1128/mcb.25.24.11005-11018.2005

PubMed ID: 19725050

Title: Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.

PubMed ID: 19725050

DOI: 10.1002/jcp.21911

PubMed ID: 19296456

Title: Membrane insertion of the FYVE domain is modulated by pH.

PubMed ID: 19296456

DOI: 10.1002/prot.22392

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22816767

Title: The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion.

PubMed ID: 22816767

DOI: 10.1111/j.1600-0854.2012.01400.x

PubMed ID: 24029230

Title: Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

PubMed ID: 24029230

DOI: 10.1016/j.ccr.2013.08.011

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 11741531

Title: Multivalent endosome targeting by homodimeric EEA1.

PubMed ID: 11741531

DOI: 10.1016/s1097-2765(01)00385-9

PubMed ID: 11230696

Title: Structural mechanism of endosome docking by the FYVE domain.

PubMed ID: 11230696

DOI: 10.1126/science.291.5509.1793

Sequence Information:

  • Length: 1411
  • Mass: 162466
  • Checksum: 51BA418F561E3411
  • Sequence:
    • MLRRILQRTP GRVGSQGSDL DSSATPINTV DVNNESSSEG FICPQCMKSL GSADELFKHY 
EAVHDAGNDS GHGGESNLAL KRDDVTLLRQ EVQDLQASLK EEKWYSEELK KELEKYQGLQ 
QQEAKPDGLV TDSSAELQSL EQQLEEAQTE NFNIKQMKDL FEQKAAQLAT EIADIKSKYD 
EERSLREAAE QKVTRLTEEL NKEATVIQDL KTELLQRPGI EDVAVLKKEL VQVQTLMDNM 
TLERERESEK LKDECKKLQS QYASSEATIS QLRSELAKGP QEVAVYVQEL QKLKSSVNEL 
TQKNQTLTEN LLKKEQDYTK LEEKHNEESV SKKNIQATLH QKDLDCQQLQ SRLSASETSL 
HRIHVELSEK GEATQKLKEE LSEVETKYQH LKAEFKQLQQ QREEKEQHGL QLQSEINQLH 
SKLLETERQL GEAHGRLKEQ RQLSSEKLMD KEQQVADLQL KLSRLEEQLK EKVTNSTELQ 
HQLDKTKQQH QEQQALQQST TAKLREAQND LEQVLRQIGD KDQKIQNLEA LLQKSKENIS 
LLEKEREDLY AKIQAGEGET AVLNQLQEKN HTLQEQVTQL TEKLKNQSES HKQAQENLHD 
QVQEQKAHLR AAQDRVLSLE TSVNELNSQL NESKEKVSQL DIQIKAKTEL LLSAEAAKTA 
QRADLQNHLD TAQNALQDKQ QELNKITTQL DQVTAKLQDK QEHCSQLESH LKEYKEKYLS 
LEQKTEELEG QIKKLEADSL EVKASKEQAL QDLQQQRQLN TDLELRATEL SKQLEMEKEI 
VSSTRLDLQK KSEALESIKQ KLTKQEEEKK ILKQDFETLS QETKIQHEEL NNRIQTTVTE 
LQKVKMEKEA LMTELSTVKD KLSKVSDSLK NSKSEFEKEN QKGKAAILDL EKTCKELKHQ 
LQVQMENTLK EQKELKKSLE KEKEASHQLK LELNSMQEQL IQAQNTLKQN EKEEQQLQGN 
INELKQSSEQ KKKQIEALQG ELKIAVLQKT ELENKLQQQL TQAAQELAAE KEKISVLQNN 
YEKSQETFKQ LQSDFYGRES ELLATRQDLK SVEEKLSLAQ EDLISNRNQI GNQNKLIQEL 
KTAKATLEQD SAKKEQQLQE RCKALQDIQK EKSLKEKELV NEKSKLAEIE EIKCRQEKEI 
TKLNEELKSH KLESIKEITN LKDAKQLLIQ QKLELQGKAD SLKAAVEQEK RNQQILKDQV 
KKEEEELKKE FIEKEAKLHS EIKEKEVGMK KHEENEAKLT MQITALNENL GTVKKEWQSS 
QRRVSELEKQ TDDLRGEIAV LEATVQNNQD ERRALLERCL KGEGEIEKLQ TKVLELQRKL 
DNTTAAVQEL GRENQSLQIK HTQALNRKWA EDNEVQNCMA CGKGFSVTVR RHHCRQCGNI 
FCAECSAKNA LTPSSKKPVR VCDACFNDLQ G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.