Details for: BCAR3

Gene ID: 8412

Symbol: BCAR3

Ensembl ID: ENSG00000137936

Description: BCAR3 adaptor protein, NSP family member

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 181.1049
    Cell Significance Index: -28.1700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 110.8643
    Cell Significance Index: -28.1200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 58.2759
    Cell Significance Index: -23.6800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 43.7840
    Cell Significance Index: -29.3800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 24.7632
    Cell Significance Index: -23.6400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.5782
    Cell Significance Index: -25.3400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.5418
    Cell Significance Index: -28.2400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.1261
    Cell Significance Index: -28.1200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.6578
    Cell Significance Index: 97.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.5886
    Cell Significance Index: 70.4600
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 2.1013
    Cell Significance Index: 26.4600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.8847
    Cell Significance Index: 130.3400
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.8351
    Cell Significance Index: 16.2900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.6058
    Cell Significance Index: 23.1000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.5700
    Cell Significance Index: 255.3500
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 1.4589
    Cell Significance Index: 20.4000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.3064
    Cell Significance Index: 35.0100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2132
    Cell Significance Index: 1095.3900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.0381
    Cell Significance Index: 79.6600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9915
    Cell Significance Index: 196.7700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.7543
    Cell Significance Index: 87.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.6649
    Cell Significance Index: 37.3100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4933
    Cell Significance Index: 176.9500
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.4860
    Cell Significance Index: 3.0200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4798
    Cell Significance Index: 10.4000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4465
    Cell Significance Index: 89.5700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4273
    Cell Significance Index: 295.5600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.4184
    Cell Significance Index: 771.6400
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.3647
    Cell Significance Index: 2.2500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.3484
    Cell Significance Index: 536.3200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.3045
    Cell Significance Index: 7.4300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2930
    Cell Significance Index: 12.9600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2597
    Cell Significance Index: 6.8300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2328
    Cell Significance Index: 10.5500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2316
    Cell Significance Index: 28.4800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2207
    Cell Significance Index: 6.3600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2200
    Cell Significance Index: 8.3300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2179
    Cell Significance Index: 11.3500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1975
    Cell Significance Index: 35.6000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1961
    Cell Significance Index: 266.6500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1910
    Cell Significance Index: 22.5300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1858
    Cell Significance Index: 9.6500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1412
    Cell Significance Index: 3.6300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1345
    Cell Significance Index: 253.3300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0938
    Cell Significance Index: 3.2600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0897
    Cell Significance Index: 4.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0841
    Cell Significance Index: 16.0100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0728
    Cell Significance Index: 39.7600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0647
    Cell Significance Index: 6.4000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0647
    Cell Significance Index: 28.6200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0621
    Cell Significance Index: 39.4500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0560
    Cell Significance Index: 25.4400
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.0391
    Cell Significance Index: 0.1700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0271
    Cell Significance Index: 0.3700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0104
    Cell Significance Index: -1.5100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0105
    Cell Significance Index: -0.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0152
    Cell Significance Index: -9.5000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0163
    Cell Significance Index: -11.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0179
    Cell Significance Index: -13.2400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0255
    Cell Significance Index: -14.3600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0364
    Cell Significance Index: -27.5300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0416
    Cell Significance Index: -3.1000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0479
    Cell Significance Index: -1.0200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0667
    Cell Significance Index: -8.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0708
    Cell Significance Index: -20.3600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0760
    Cell Significance Index: -12.9700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0861
    Cell Significance Index: -18.1400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0890
    Cell Significance Index: -11.5000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0951
    Cell Significance Index: -4.4700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0991
    Cell Significance Index: -13.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1005
    Cell Significance Index: -6.1800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1327
    Cell Significance Index: -1.9000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1444
    Cell Significance Index: -14.7500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1474
    Cell Significance Index: -4.7200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1573
    Cell Significance Index: -2.7200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1596
    Cell Significance Index: -3.3100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1757
    Cell Significance Index: -20.1400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1800
    Cell Significance Index: -18.7400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.2052
    Cell Significance Index: -1.2400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2066
    Cell Significance Index: -23.5800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2686
    Cell Significance Index: -18.0600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2944
    Cell Significance Index: -23.3200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2977
    Cell Significance Index: -8.3200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2980
    Cell Significance Index: -21.0700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3202
    Cell Significance Index: -6.2500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3269
    Cell Significance Index: -20.0400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3398
    Cell Significance Index: -21.9300
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.3698
    Cell Significance Index: -5.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3880
    Cell Significance Index: -9.7000
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.4121
    Cell Significance Index: -6.2700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4546
    Cell Significance Index: -28.6600
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.4770
    Cell Significance Index: -5.9000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4799
    Cell Significance Index: -7.0900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5099
    Cell Significance Index: -26.7700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5470
    Cell Significance Index: -20.0800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5586
    Cell Significance Index: -18.2900
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.5762
    Cell Significance Index: -4.8400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5862
    Cell Significance Index: -18.6700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6094
    Cell Significance Index: -21.3500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.6157
    Cell Significance Index: -17.6500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** BCAR3 is characterized by its ability to bind to phosphotyrosine residues, which is essential for its function as an adaptor protein. Its interaction with various kinases and GTPases suggests that it plays a pivotal role in regulating signal transduction pathways. Additionally, its involvement in positive regulation of cell population proliferation, gtpase activity, and MAPK cascade indicates that it may be involved in promoting cell growth and survival. **Pathways and Functions** BCAR3 is involved in several signaling pathways, including: 1. **Endothelin receptor signaling pathway**: BCAR3 interacts with endothelin receptors, leading to the activation of downstream signaling pathways that regulate vascular tone and cell proliferation. 2. **Epidermal growth factor receptor signaling pathway**: BCAR3 binds to phosphorylated EGF receptors, facilitating the activation of downstream signaling pathways that regulate cell growth and differentiation. 3. **Insulin receptor signaling pathway**: BCAR3 interacts with insulin receptors, leading to the activation of downstream signaling pathways that regulate glucose metabolism and cell growth. 4. **Focal adhesion**: BCAR3 is involved in the regulation of focal adhesions, which are critical for cell adhesion and migration. 5. **Guanyl-nucleotide exchange factor activity**: BCAR3 interacts with guanyl-nucleotide exchange factors, facilitating the activation of small GTPases that regulate various cellular processes. **Clinical Significance** BCAR3 has been implicated in various diseases, including: 1. **Breast cancer**: BCAR3 has been identified as a potential target for anti-estrogen therapy, as it is involved in regulating estrogen receptor signaling pathways. 2. **Retinal diseases**: BCAR3 has been implicated in the pathogenesis of retinal diseases, including age-related macular degeneration and retinitis pigmentosa. 3. **Neurodegenerative diseases**: BCAR3 has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. 4. **Kidney disease**: BCAR3 has been implicated in the pathogenesis of kidney disease, including diabetic nephropathy and chronic kidney disease. In conclusion, BCAR3 is a multifunctional adaptor protein that plays a critical role in regulating various cellular processes, including signal transduction, cell proliferation, and differentiation. Its involvement in multiple diseases highlights its potential as a therapeutic target for the development of novel treatments.

Genular Protein ID: 3011121722

Symbol: BCAR3_HUMAN

Name: Breast cancer anti-estrogen resistance protein 3

UniProtKB Accession Codes:

O75815 D3DT43 Q5TEW3 Q6UW40 Q9BR50

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 6 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9582273

Title: Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells.

PubMed ID: 9582273

DOI: 10.1093/emboj/17.10.2799

PubMed ID: 10187783

Title: NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway.

PubMed ID: 10187783

DOI: 10.1074/jbc.274.15.10047

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18722344

Title: BCAR3 regulates EGF-induced DNA synthesis in normal human breast MCF-12A cells.

PubMed ID: 18722344

DOI: 10.1016/j.bbrc.2008.08.040

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19086031

Title: Pyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreading.

PubMed ID: 19086031

DOI: 10.1002/jcp.21649

PubMed ID: 19103205

Title: Structural insights into the association between BCAR3 and Cas family members, an atypical complex implicated in anti-oestrogen resistance.

PubMed ID: 19103205

DOI: 10.1016/j.jmb.2008.12.010

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22801373

Title: Protein tyrosine phosphatase alpha phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.

PubMed ID: 22801373

DOI: 10.1128/mcb.00214-12

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24216110

Title: Functional roles of BCAR3 in the signaling pathways of insulin leading to DNA synthesis, membrane ruffling and GLUT4 translocation.

PubMed ID: 24216110

DOI: 10.1016/j.bbrc.2013.10.161

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 22081014

Title: NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.

PubMed ID: 22081014

DOI: 10.1038/nsmb.2152

Sequence Information:

  • Length: 825
  • Mass: 92566
  • Checksum: C55D61BB4AC7D0F2
  • Sequence:
    • MAAGKFASLP RNMPVNHQFP LASSMDLLSS RSPLAEHRPD AYQDVSIHGT LPRKKKGPPP 
IRSCDDFSHM GTLPHSKSPR QNSPVTQDGI QESPWQDRHG ETFTFRDPHL LDPTVEYVKF 
SKERHIMDRT PEKLKKELEE ELLLSSEDLR SHAWYHGRIP RQVSENLVQR DGDFLVRDSL 
SSPGNFVLTC QWKNLAQHFK INRTVLRLSE AYSRVQYQFE MESFDSIPGL VRCYVGNRRP 
ISQQSGAIIF QPINRTVPLR CLEEHYGTSP GQAREGSLTK GRPDVAKRLS LTMGGVQARE 
QNLPRGNLLR NKEKSGSQPA CLDHMQDRRA LSLKAHQSES YLPIGCKLPP QSSGVDTSPC 
PNSPVFRTGS EPALSPAVVR RVSSDARAGE ALRGSDSQLC PKPPPKPCKV PFLKVPSSPS 
AWLNSEANYC ELNPAFATGC GRGAKLPSCA QGSHTELLTA KQNEAPGPRN SGVNYLILDD 
DDRERPWEPA AAQMEKGQWD KGEFVTPLLE TVSSFRPNEF ESKFLPPENK PLETAMLKRA 
KELFTNNDPK VIAQHVLSMD CRVARILGVS EEMRRNMGVS SGLELITLPH GHQLRLDIIE 
RHNTMAIGIA VDILGCTGTL EDRAATLSKI IQVAVELKDS MGDLYSFSAL MKALEMPQIT 
RLEKTWTALR HQYTQTAILY EKQLKPFSKL LHEGRESTCV PPNNVSVPLL MPLVTLMERQ 
AVTFEGTDMW EKNDQSCEIM LNHLATARFM AEAADSYRMN AERILAGFQP DEEMNEICKT 
EFQMRLLWGS KGAQVNQTER YEKFNQILTA LSRKLEPPPV KQAEL

Genular Protein ID: 1648869979

Symbol: B3KP06_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KP06

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 825
  • Mass: 92512
  • Checksum: 5B248FC2AD59AFA2
  • Sequence:
    • MAAGKFASLP RNMPVNHQFP LASSMDLLSS RSPLAEHRPD AYQDVSIHGT LPRKKKGPPP 
IRSCDDFSHM GTLPHSKSPR QNSPVTQDGI QESPWQDRHG ETFTFRDPHL LDPTVEYVKF 
SKERHIMDRT PEKLKKELEE ELLLSSEDLR SHAWYHGRIP RQVSENLVQR DGDFLVRDSL 
SSPGNFVLTC QWKNLAQHFK INRTVLRLSE AYSRVQYQFE MESFDSIPGL VRCYVGNRRP 
ISQQSGAIIF QPINRTVPLR CLEEHYGTSP GQAREGSLTK GRPDVAKRLS LTMGGVQARE 
QNLPRGNLLR NKEKSGSQPA CLDHMQDRRA LSLKAHQSES YLPIGCKLPP QSSGVDTSPC 
PNSPVFRTGS EPALSPAVVR RVSSDARAGE ALRGSDSQLC PKPPPKPCKV PFLKVPSSPS 
AWLNSEANYC ELNPAFATGC GRGAKLPSCA QGSHTELLTA KQNEAPGPRN SGVNYLILDD 
DDRERPWEPA AAQMEKGQWD KGEFVTPLLE TVSSFRPNEF ESKFLPPENK PLETAMLKRA 
KELFTNNDPK VIAQHVLSMD CRVARILGVS EEMRRNMGVS SGLELITLPH GHQLCLDIIE 
RHNTMAIGIA VDILGCTGTL EDRAATLSKI IQVAVELKDS MGDLYSFSAL MKALEMPQIT 
RLEKTWTALR HQYTQTAILY EKQLKPFSKL LHEGRESTCV PPNNVSVPLL MPLVTLMERQ 
AVTFEGTDMW EKNDQSCEIM LNHLATARFM AEAADSYRMN AERILAGFQP DEEMNEICKT 
EFQMRLLWGS KGAQVNQTER YEKFNQILTA LSRKLEPPPV KQAEL

Genular Protein ID: 2199409565

Symbol: B3KNL6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KNL6

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 605
  • Mass: 67171
  • Checksum: 7550777AC9C366A2
  • Sequence:
    • MESFDSIPGL VRCYVGNRRP ISQQSGAIIF QPINRTVPLR CLEEHYGTSP GQAREGSLTK 
GRPDVAKRLS LTMGGVQARE QNLPRGNLLR NKEKSGSQPA CLDHMQDRRA LSLKAHQSES 
YLPIGCKLPP QSSGVDTSPC PNSPVFRTGS EPALSPAVVR RVSSDARAGE ALRGSDSQLC 
PKPPPKPCKV PFLKVPSSPS AWLNSEANYC ELNPAFATGC GRGAKLPSCA QGSHTELLTA 
KQNEAPGPRN SGVNYLILDD DDRERPWEPA AAQMEKGQWD KGEFVTPLLE TVSSFRPNEF 
ESKFLPPENK PLETAMLKRA KELFTNNDPK VIAQHVLSMD CRVARILGVS EEMRRNMGVS 
SGLELITLPH GHQLRLDIIE RHNTMAIGIA VDILGCTGTL EDRAATLSKI IQVAVELKDS 
MGDLYSFSAL MKALEMPQIT RLEKTWTALR HQYTQTAILY EKQLKPFSKL LHEGRESTCV 
PPNNVSVPLL MPLVTLMERQ AVTFEGTDMW EKNDQSCEIM LNHLATARFM AEAADSYRMN 
AERILAGFQP DEEMNEICKT EFQMRLLWGS KGAQVNQTER YEKFNQILTA LSRKLEPPPV 
KQAEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.