Details for: TTF2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 83.4484
Cell Significance Index: -12.9800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 52.8695
Cell Significance Index: -13.4100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 33.4025
Cell Significance Index: -13.5700 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 14.2656
Cell Significance Index: -13.6200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.1229
Cell Significance Index: -16.1800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.8084
Cell Significance Index: -15.5600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.3221
Cell Significance Index: -13.2800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.1928
Cell Significance Index: -16.5500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 3.3903
Cell Significance Index: -7.4200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.9843
Cell Significance Index: 196.2900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.0392
Cell Significance Index: 58.3200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7812
Cell Significance Index: 84.9700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.7723
Cell Significance Index: 20.7000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.7564
Cell Significance Index: 21.1400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.7393
Cell Significance Index: 120.2500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.7021
Cell Significance Index: 42.1500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6266
Cell Significance Index: 565.7300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5128
Cell Significance Index: 14.7800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.5102
Cell Significance Index: 101.2500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4288
Cell Significance Index: 27.6700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4116
Cell Significance Index: 21.3800 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.4104
Cell Significance Index: 10.4900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3753
Cell Significance Index: 8.1300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3242
Cell Significance Index: 58.4500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.3195
Cell Significance Index: 37.6800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.3169
Cell Significance Index: 36.9300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3086
Cell Significance Index: 21.3400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3026
Cell Significance Index: 37.2100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2779
Cell Significance Index: 12.6000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.2264
Cell Significance Index: 123.6200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.2044
Cell Significance Index: 4.2400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1956
Cell Significance Index: 70.1800 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.1748
Cell Significance Index: 1.6100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1650
Cell Significance Index: 72.9400 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1542
Cell Significance Index: 3.0100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1394
Cell Significance Index: 3.8000 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.1278
Cell Significance Index: 2.0500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1182
Cell Significance Index: 22.4900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1082
Cell Significance Index: 2.7100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1057
Cell Significance Index: 14.5200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0732
Cell Significance Index: 14.6900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0707
Cell Significance Index: 5.4300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0681
Cell Significance Index: 2.1800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0557
Cell Significance Index: 2.6200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0331
Cell Significance Index: 5.6600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0194
Cell Significance Index: 36.5300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0192
Cell Significance Index: 12.2100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0045
Cell Significance Index: 8.2500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0033
Cell Significance Index: 5.1100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0022
Cell Significance Index: 1.0100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0012
Cell Significance Index: 1.6800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0011
Cell Significance Index: 0.0300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0009
Cell Significance Index: 0.1100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0010
Cell Significance Index: -0.0700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0025
Cell Significance Index: -0.1100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0095
Cell Significance Index: -6.9300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0117
Cell Significance Index: -0.2500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0171
Cell Significance Index: -12.9700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0197
Cell Significance Index: -2.8600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0213
Cell Significance Index: -15.7500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0236
Cell Significance Index: -1.1000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0237
Cell Significance Index: -0.6100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0251
Cell Significance Index: -0.9500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0261
Cell Significance Index: -14.7400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0288
Cell Significance Index: -18.0000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0343
Cell Significance Index: -1.2100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0358
Cell Significance Index: -4.1000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0378
Cell Significance Index: -10.8900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0434
Cell Significance Index: -4.4300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0496
Cell Significance Index: -0.8500 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0605
Cell Significance Index: -7.7500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0707
Cell Significance Index: -5.2700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0839
Cell Significance Index: -17.6800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0858
Cell Significance Index: -1.1700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1233
Cell Significance Index: -7.5600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1314
Cell Significance Index: -8.8400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1389
Cell Significance Index: -8.5400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1402
Cell Significance Index: -3.7500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1433
Cell Significance Index: -14.9200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1729
Cell Significance Index: -13.6900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1917
Cell Significance Index: -6.6600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1975
Cell Significance Index: -5.8000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2037
Cell Significance Index: -5.8400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2089
Cell Significance Index: -10.8800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2095
Cell Significance Index: -3.0000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2107
Cell Significance Index: -13.2800 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.2207
Cell Significance Index: -1.8000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2488
Cell Significance Index: -3.7500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2541
Cell Significance Index: -7.2500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.2599
Cell Significance Index: -2.6900 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2610
Cell Significance Index: -6.0300 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.2834
Cell Significance Index: -1.9200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2865
Cell Significance Index: -4.8000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.2950
Cell Significance Index: -8.6900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.2989
Cell Significance Index: -6.3900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3013
Cell Significance Index: -15.8200 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.3176
Cell Significance Index: -5.8700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3183
Cell Significance Index: -8.3700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3368
Cell Significance Index: -7.3800 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.3510
Cell Significance Index: -4.9200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 774030859
Symbol: TTF2_HUMAN
Name: Transcription termination factor 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9748214
Title: A human RNA polymerase II transcription termination factor is a SWI2/SNF2 family member.
PubMed ID: 9748214
PubMed ID: 12927788
Title: hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing.
PubMed ID: 12927788
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10455150
Title: Human transcription release factor 2 dissociates RNA polymerases I and II stalled at a cyclobutane thymine dimer.
PubMed ID: 10455150
PubMed ID: 15125840
Title: Involvement of transcription termination factor 2 in mitotic repression of transcription elongation.
PubMed ID: 15125840
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 1162
- Mass: 129588
- Checksum: 858BAA22B2D2D5C9
- Sequence:
MEEVRCPEHG TFCFLKTGVR DGPNKGKSFY VCRADTCSFV RATDIPVSHC LLHEDFVVEL QGLLLPQDKK EYRLFFRCIR SKAEGKRWCG SIPWQDPDSK EHSVSNKSQH ASETFHHSSN WLRNPFKVLD KNQEPALWKQ LIKGEGEEKK ADKKQREKGD QLFDQKKEQK PEMMEKDLSS GLVPKKKQSV VQEKKQEEGA EIQCEAETGG THKRDFSEIK SQQCQGNELT RPSASSQEKS SGKSQDVQRE SEPLREKVTQ LLPQNVHSHN SISKPQKGGP LNKEYTNWEA KETKAKDGPS IQATQKSLPQ GHFQERPETH SVPAPGGPAA QAAPAAPGLS LGEGREAATS SDDEEEDDVV FVSSKPGSPL LFDSTLDLET KENLQFPDRS VQRKVSPASG VSKKVEPSDP VARRVYLTTQ LKQKKSTLAS VNIQALPDKG QKLIKQIQEL EEVLSGLTLS PEQGTNEKSN SQVPQQSHFT KTTTGPPHLV PPQPLPRRGT QPVGSLELKS ACQVTAGGSS QCYRGHTNQD HVHAVWKITS EAIGQLHRSL ESCPGETVVA EDPAGLKVPL LLHQKQALAW LLWRESQKPQ GGILADDMGL GKTLTMIALI LTQKNQEKKE EKEKSTALTW LSKDDSCDFT SHGTLIICPA SLIHHWKNEV EKRVNSNKLR VYLYHGPNRD SRARVLSTYD IVITTYSLVA KEIPTNKQEA EIPGANLNVE GTSTPLLRIA WARIILDEAH NVKNPRVQTS IAVCKLQACA RWAVTGTPIQ NNLLDMYSLL KFLRCSPFDE FNLWRSQVDN GSKKGGERLS ILTKSLLLRR TKDQLDSTGR PLVILPQRKF QLHHLKLSED EETVYNVFFA RSRSALQSYL KRHESRGNQS GRSPNNPFSR VALEFGSEEP RHSEAADSPR SSTVHILSQL LRLRQCCCHL SLLKSALDPM ELKGEGLVLS LEEQLSALTL SELRDSEPSS TVSLNGTFFK MELFEGMRES TKISSLLAEL EAIQRNSASQ KSVIVSQWTN MLKVVALHLK KHGLTYATID GSVNPKQRMD LVEAFNHSRG PQVMLISLLA GGVGLNLTGG NHLFLLDMHW NPSLEDQACD RIYRVGQQKD VVIHRFVCEG TVEEKILQLQ EKKKDLAKQV LSGSGESVTK LTLADLRVLF GI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.