Details for: CDC42BPA

Gene ID: 8476

Symbol: CDC42BPA

Ensembl ID: ENSG00000143776

Description: CDC42 binding protein kinase alpha

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 817.2221
    Cell Significance Index: -127.1200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 521.0071
    Cell Significance Index: -132.1500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 272.0691
    Cell Significance Index: -128.4500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 262.2477
    Cell Significance Index: -106.5400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 111.7264
    Cell Significance Index: -106.6700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 106.9260
    Cell Significance Index: -131.8400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 46.8931
    Cell Significance Index: -125.6200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 33.8034
    Cell Significance Index: -133.3900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 33.3503
    Cell Significance Index: -72.9900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 3.6343
    Cell Significance Index: 52.2700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.5470
    Cell Significance Index: 1272.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.2984
    Cell Significance Index: 185.0900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 3.2439
    Cell Significance Index: 248.9300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.0919
    Cell Significance Index: 620.2400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 2.8473
    Cell Significance Index: 175.0100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.7122
    Cell Significance Index: 182.3700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.4728
    Cell Significance Index: 1710.2700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.4525
    Cell Significance Index: 63.0400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 2.4488
    Cell Significance Index: 108.3200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 2.3421
    Cell Significance Index: 88.6900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.2350
    Cell Significance Index: 64.4000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.1576
    Cell Significance Index: 42.1100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9741
    Cell Significance Index: 391.7600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.9615
    Cell Significance Index: 42.9500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.9160
    Cell Significance Index: 45.9500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.6588
    Cell Significance Index: 20.5800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.6183
    Cell Significance Index: 1461.1600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.5930
    Cell Significance Index: 45.4600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.3681
    Cell Significance Index: 1860.2500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.2279
    Cell Significance Index: 55.6600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.1589
    Cell Significance Index: 1784.1500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.1171
    Cell Significance Index: 2060.1800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.0167
    Cell Significance Index: 183.2800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.9195
    Cell Significance Index: 1731.2500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.8533
    Cell Significance Index: 18.2400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8208
    Cell Significance Index: 89.2800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.7487
    Cell Significance Index: 12.8300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6353
    Cell Significance Index: 78.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.5580
    Cell Significance Index: 253.2400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3704
    Cell Significance Index: 36.6400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2566
    Cell Significance Index: 162.9600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2008
    Cell Significance Index: 109.6800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.1639
    Cell Significance Index: 0.9900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0545
    Cell Significance Index: 7.4900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0368
    Cell Significance Index: -22.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0623
    Cell Significance Index: -11.8500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0633
    Cell Significance Index: -46.9200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0722
    Cell Significance Index: -10.4900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1125
    Cell Significance Index: -82.5000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1291
    Cell Significance Index: -57.0600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1577
    Cell Significance Index: -88.9600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1641
    Cell Significance Index: -124.2300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2300
    Cell Significance Index: -39.2800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2457
    Cell Significance Index: -31.5000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3773
    Cell Significance Index: -79.4700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.3995
    Cell Significance Index: -64.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4131
    Cell Significance Index: -118.8500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.4383
    Cell Significance Index: -12.2500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4548
    Cell Significance Index: -47.3600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4661
    Cell Significance Index: -24.2800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.7368
    Cell Significance Index: -50.9500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7474
    Cell Significance Index: -39.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.8172
    Cell Significance Index: -105.5800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.8511
    Cell Significance Index: -86.9400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.8570
    Cell Significance Index: -99.8700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.8617
    Cell Significance Index: -30.2800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.8766
    Cell Significance Index: -100.4300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.9064
    Cell Significance Index: -103.4600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.0347
    Cell Significance Index: -53.7500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -1.0795
    Cell Significance Index: -127.3100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.1700
    Cell Significance Index: -14.5900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.1734
    Cell Significance Index: -54.7100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.2283
    Cell Significance Index: -26.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.2709
    Cell Significance Index: -80.1000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -1.2827
    Cell Significance Index: -18.4200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.4386
    Cell Significance Index: -113.9400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.4558
    Cell Significance Index: -108.5000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -1.5473
    Cell Significance Index: -109.4300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.5874
    Cell Significance Index: -97.3200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.6280
    Cell Significance Index: -76.5100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.6318
    Cell Significance Index: -20.6000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.7047
    Cell Significance Index: -28.7200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.9418
    Cell Significance Index: -125.2800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.9792
    Cell Significance Index: -29.2200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -2.0503
    Cell Significance Index: -40.5400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -2.1282
    Cell Significance Index: -45.3300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -2.1859
    Cell Significance Index: -71.5700
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -2.2066
    Cell Significance Index: -33.5700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -2.2300
    Cell Significance Index: -54.4100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -2.2544
    Cell Significance Index: -71.8000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -2.3282
    Cell Significance Index: -74.5700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -2.3553
    Cell Significance Index: -25.6600
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -2.3649
    Cell Significance Index: -34.9100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -2.3998
    Cell Significance Index: -48.1800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -2.4628
    Cell Significance Index: -52.2700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -2.5645
    Cell Significance Index: -30.5700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -2.7845
    Cell Significance Index: -96.7600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.8240
    Cell Significance Index: -98.9300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -2.8473
    Cell Significance Index: -45.6800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -2.9807
    Cell Significance Index: -49.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cellular localization:** CDC42BPA is predominantly expressed in Purkinje cells, neuronal brush cells, anterior lens cells, and various immune cells, including inhibitory interneurons, granule cells, and kidney interstitial fibroblasts. 2. **Protein kinase activity:** CDC42BPA is a serine/threonine kinase that phosphorylates specific amino acid residues, thereby modulating protein function and signaling. 3. **GTPase cycle regulation:** CDC42BPA interacts with Rho GTPases, modulating their activity and influencing cytoskeleton organization, cell migration, and signaling. **Pathways and Functions:** 1. **Actin cytoskeleton organization:** CDC42BPA regulates the organization of the actin cytoskeleton, which is essential for cell migration, adhesion, and shape changes. 2. **Rho GTPase cycle:** CDC42BPA modulates the activity of Rho GTPases, influencing their downstream signaling pathways, including cytoskeleton organization, cell migration, and cell proliferation. 3. **Cell migration:** CDC42BPA plays a critical role in regulating immune cell migration, particularly in the context of tissue inflammation and immune responses. 4. **Signaling by Rho GTPases:** CDC42BPA interacts with Rho GTPases, modulating their signaling pathways, which are essential for immune cell function, including migration, proliferation, and differentiation. **Clinical Significance:** 1. **Immune cell migration disorders:** Alterations in CDC42BPA expression or function may contribute to immune cell migration disorders, such as leukocyte adhesion deficiency or immune-related inflammatory diseases. 2. **Cancer progression:** CDC42BPA may be involved in the regulation of cancer cell migration and invasion, highlighting its potential as a therapeutic target in cancer therapy. 3. **Neurological disorders:** CDC42BPA expression and function may be altered in neurological disorders, such as Parkinson's disease or multiple sclerosis, suggesting its potential as a biomarker or therapeutic target. 4. **Regulation of immune responses:** CDC42BPA may play a role in regulating immune responses, including the activation and regulation of immune cells, such as T cells and B cells. In conclusion, CDC42BPA is a critical regulator of immune cell migration, cytoskeleton organization, and signaling pathways. Further research is necessary to fully elucidate its role in immune cell function and its potential applications in immunotherapy and disease treatment.

Genular Protein ID: 1685480209

Symbol: MRCKA_HUMAN

Name: Serine/threonine-protein kinase MRCK alpha

UniProtKB Accession Codes:

Q5VT25 O75039 Q59GZ1 Q5H9N9 Q5T797 Q5VT26 Q5VT27 Q86XX2 Q86XX3 Q99646

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 4 CPTAC 1 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 2 EMBL 34 Ensembl 4 ExpressionAtlas 1 GO 17 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 16 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 9 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 4 RefSeq 5 Rhea 6 SIGNOR 1 SMART 6 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15723050

Title: Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion.

PubMed ID: 15723050

DOI: 10.1038/ncb1230

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 9092543

Title: Cloning and chromosomal location of a novel member of the myotonic dystrophy family of protein kinases.

PubMed ID: 9092543

DOI: 10.1074/jbc.272.15.10013

PubMed ID: 9455484

Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

PubMed ID: 9455484

DOI: 10.1093/dnares/4.5.345

PubMed ID: 9418861

Title: Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization.

PubMed ID: 9418861

DOI: 10.1128/mcb.18.1.130

PubMed ID: 11399775

Title: Phosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeleton.

PubMed ID: 11399775

DOI: 10.1074/jbc.m102615200

PubMed ID: 11340065

Title: Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha.

PubMed ID: 11340065

DOI: 10.1074/jbc.c100196200

PubMed ID: 11283256

Title: Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase alpha.

PubMed ID: 11283256

DOI: 10.1128/mcb.21.8.2767-2778.2001

PubMed ID: 12568720

Title: Genomic organization of human myotonic dystrophy kinase-related Cdc42-binding kinase alpha reveals multiple alternative splicing and functional diversity.

PubMed ID: 12568720

DOI: 10.1016/s0378-1119(02)01185-x

PubMed ID: 18854160

Title: A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.

PubMed ID: 18854160

DOI: 10.1016/j.cell.2008.09.018

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20188707

Title: Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake.

PubMed ID: 20188707

DOI: 10.1016/j.bbrc.2010.02.148

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21457715

Title: Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase.

PubMed ID: 21457715

DOI: 10.1016/j.febslet.2011.03.054

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29162624

Title: MRCKalpha is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

PubMed ID: 29162624

DOI: 10.1083/jcb.201703044

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 1732
  • Mass: 197307
  • Checksum: 48B10F81B5405A0A
  • Sequence:
    • MSGEVRLRQL EQFILDGPAQ TNGQCFSVET LLDILICLYD ECNNSPLRRE KNILEYLEWA 
KPFTSKVKQM RLHREDFEIL KVIGRGAFGE VAVVKLKNAD KVFAMKILNK WEMLKRAETA 
CFREERDVLV NGDNKWITTL HYAFQDDNNL YLVMDYYVGG DLLTLLSKFE DRLPEDMARF 
YLAEMVIAID SVHQLHYVHR DIKPDNILMD MNGHIRLADF GSCLKLMEDG TVQSSVAVGT 
PDYISPEILQ AMEDGKGRYG PECDWWSLGV CMYEMLYGET PFYAESLVET YGKIMNHKER 
FQFPAQVTDV SENAKDLIRR LICSREHRLG QNGIEDFKKH PFFSGIDWDN IRNCEAPYIP 
EVSSPTDTSN FDVDDDCLKN SETMPPPTHT AFSGHHLPFV GFTYTSSCVL SDRSCLRVTA 
GPTSLDLDVN VQRTLDNNLA TEAYERRIKR LEQEKLELSR KLQESTQTVQ ALQYSTVDGP 
LTASKDLEIK NLKEEIEKLR KQVTESSHLE QQLEEANAVR QELDDAFRQI KAYEKQIKTL 
QQEREDLNKE LVQASERLKN QSKELKDAHC QRKLAMQEFM EINERLTELH TQKQKLARHV 
RDKEEEVDLV MQKVESLRQE LRRTERAKKE LEVHTEALAA EASKDRKLRE QSEHYSKQLE 
NELEGLKQKQ ISYSPGVCSI EHQQEITKLK TDLEKKSIFY EEELSKREGI HANEIKNLKK 
ELHDSEGQQL ALNKEIMILK DKLEKTRRES QSEREEFESE FKQQYEREKV LLTEENKKLT 
SELDKLTTLY ENLSIHNQQL EEEVKDLADK KESVAHWEAQ ITEIIQWVSD EKDARGYLQA 
LASKMTEELE ALRNSSLGTR ATDMPWKMRR FAKLDMSARL ELQSALDAEI RAKQAIQEEL 
NKVKASNIIT ECKLKDSEKK NLELLSEIEQ LIKDTEELRS EKGIEHQDSQ HSFLAFLNTP 
TDALDQFERS PSCTPASKGR RTVDSTPLSV HTPTLRKKGC PGSTGFPPKR KTHQFFVKSF 
TTPTKCHQCT SLMVGLIRQG CSCEVCGFSC HITCVNKAPT TCPVPPEQTK GPLGIDPQKG 
IGTAYEGHVR IPKPAGVKKG WQRALAIVCD FKLFLYDIAE GKASQPSVVI SQVIDMRDEE 
FSVSSVLASD VIHASRKDIP CIFRVTASQL SASNNKCSIL MLADTENEKN KWVGVLSELH 
KILKKNKFRD RSVYVPKEAY DSTLPLIKTT QAAAIIDHER IALGNEEGLF VVHVTKDEII 
RVGDNKKIHQ IELIPNDQLV AVISGRNRHV RLFPMSALDG RETDFYKLSE TKGCQTVTSG 
KVRHGALTCL CVAMKRQVLC YELFQSKTRH RKFKEIQVPY NVQWMAIFSE QLCVGFQSGF 
LRYPLNGEGN PYSMLHSNDH TLSFIAHQPM DAICAVEISS KEYLLCFNSI GIYTDCQGRR 
SRQQELMWPA NPSSCCYNAP YLSVYSENAV DIFDVNSMEW IQTLPLKKVR PLNNEGSLNL 
LGLETIRLIY FKNKMAEGDE LVVPETSDNS RKQMVRNINN KRRYSFRVPE EERMQQRREM 
LRDPEMRNKL ISNPTNFNHI AHMGPGDGIQ ILKDLPMNPR PQESRTVFSG SVSIPSITKS 
RPEPGRSMSA SSGLSARSSA QNGSALKREF SGGSYSAKRQ PMPSPSEGSL SSGGMDQGSD 
APARDFDGED SDSPRHSTAS NSSNLSSPPS PASPRKTKSL SLESTDRGSW DP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.