Details for: NDST2

Gene ID: 8509

Symbol: NDST2

Ensembl ID: ENSG00000166507

Description: N-deacetylase and N-sulfotransferase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 46.7067
    Cell Significance Index: -7.2700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 29.7268
    Cell Significance Index: -7.5400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 16.5905
    Cell Significance Index: -6.7400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 15.1054
    Cell Significance Index: -7.7700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 7.2480
    Cell Significance Index: -6.9200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 6.1032
    Cell Significance Index: -7.5300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 2.1155
    Cell Significance Index: 34.8600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.9234
    Cell Significance Index: -7.5900
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.6870
    Cell Significance Index: 4.5600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5047
    Cell Significance Index: 30.3000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4219
    Cell Significance Index: 8.9900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.3706
    Cell Significance Index: 9.9300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3375
    Cell Significance Index: 36.7200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3334
    Cell Significance Index: 301.0400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2948
    Cell Significance Index: 59.1400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2391
    Cell Significance Index: 43.1100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2263
    Cell Significance Index: 22.3900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2229
    Cell Significance Index: 4.8800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1976
    Cell Significance Index: 32.1500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1840
    Cell Significance Index: 22.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1839
    Cell Significance Index: 12.7200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1496
    Cell Significance Index: 53.6500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.1455
    Cell Significance Index: 1.3400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1162
    Cell Significance Index: 5.8700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0983
    Cell Significance Index: 5.1200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0856
    Cell Significance Index: 6.5700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.0844
    Cell Significance Index: 1.5600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0795
    Cell Significance Index: 2.2800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0708
    Cell Significance Index: 8.2500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0676
    Cell Significance Index: 1.6900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0664
    Cell Significance Index: 12.6400
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0625
    Cell Significance Index: 0.8800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0604
    Cell Significance Index: 1.7400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0591
    Cell Significance Index: 1.2800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0548
    Cell Significance Index: 7.0300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0371
    Cell Significance Index: 1.7300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0310
    Cell Significance Index: 1.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0309
    Cell Significance Index: 1.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0114
    Cell Significance Index: 0.6400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.0081
    Cell Significance Index: 0.1300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0068
    Cell Significance Index: 0.2400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0030
    Cell Significance Index: 1.6500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0002
    Cell Significance Index: 0.0100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0040
    Cell Significance Index: -0.4700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0040
    Cell Significance Index: -7.5800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0051
    Cell Significance Index: -9.3200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0057
    Cell Significance Index: -4.2300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0060
    Cell Significance Index: -9.1800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0060
    Cell Significance Index: -2.6600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0069
    Cell Significance Index: -9.3300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0083
    Cell Significance Index: -6.2800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0094
    Cell Significance Index: -6.8700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0104
    Cell Significance Index: -5.8500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0115
    Cell Significance Index: -7.3200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0119
    Cell Significance Index: -1.6400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0135
    Cell Significance Index: -0.5100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0142
    Cell Significance Index: -0.3800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0154
    Cell Significance Index: -0.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0171
    Cell Significance Index: -1.9600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0174
    Cell Significance Index: -7.8800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0180
    Cell Significance Index: -5.1800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0226
    Cell Significance Index: -3.8600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0313
    Cell Significance Index: -1.9700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0352
    Cell Significance Index: -4.5500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0372
    Cell Significance Index: -3.8000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0377
    Cell Significance Index: -1.7700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0383
    Cell Significance Index: -7.6100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0389
    Cell Significance Index: -8.2000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0441
    Cell Significance Index: -1.2000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0491
    Cell Significance Index: -7.1400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0539
    Cell Significance Index: -4.0200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0600
    Cell Significance Index: -3.6800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0613
    Cell Significance Index: -0.5000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0628
    Cell Significance Index: -0.9000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0707
    Cell Significance Index: -2.0800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0710
    Cell Significance Index: -1.9000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0796
    Cell Significance Index: -5.1400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0922
    Cell Significance Index: -7.3000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0923
    Cell Significance Index: -6.5300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0938
    Cell Significance Index: -2.2500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1109
    Cell Significance Index: -2.3700
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1112
    Cell Significance Index: -1.5800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1129
    Cell Significance Index: -7.5900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1195
    Cell Significance Index: -2.7600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1202
    Cell Significance Index: -1.6400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1243
    Cell Significance Index: -2.1500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1265
    Cell Significance Index: -2.6900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1329
    Cell Significance Index: -4.3500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1345
    Cell Significance Index: -4.2900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1348
    Cell Significance Index: -7.0800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1384
    Cell Significance Index: -2.9900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1431
    Cell Significance Index: -5.8700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1471
    Cell Significance Index: -4.7100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1559
    Cell Significance Index: -5.4600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1680
    Cell Significance Index: -3.3700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1683
    Cell Significance Index: -2.8300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1708
    Cell Significance Index: -6.2700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1780
    Cell Significance Index: -3.5200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1814
    Cell Significance Index: -4.7700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1838
    Cell Significance Index: -7.9900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Bifunctional enzyme:** NDST2 exhibits dual enzymatic activity, catalyzing both N-deacetylation and N-sulfation of heparan sulfate. 2. **Heparan sulfate metabolism:** This enzyme is crucial for the biosynthesis and modification of HSPGs, which are essential for various cellular processes, including cell signaling, immune responses, and tissue development. 3. **Tissue-specific expression:** NDST2 is highly expressed in kidney proximal convoluted tubule epithelial cells, neural progenitor cells, and GABAergic interneurons, highlighting its importance in specific tissue contexts. 4. **Regulation of angiotensin levels:** NDST2 has been implicated in the regulation of angiotensin levels in the blood, suggesting a potential role in cardiovascular disease. **Pathways and Functions:** 1. **Glycosaminoglycan metabolism:** NDST2 is involved in the biosynthesis and modification of HSPGs, which are critical for cell signaling, immune responses, and tissue development. 2. **Heparan sulfate proteoglycan biosynthetic process:** This enzyme is essential for the production of HSPGs, which are involved in various cellular processes, including cell adhesion, migration, and signaling. 3. **Golgi apparatus and membrane:** NDST2 is localized to the Golgi apparatus and membrane, where it regulates the modification of HSPGs. 4. **Mast cell-mediated immunity:** NDST2 has been implicated in the regulation of mast cell-mediated immunity, suggesting a potential role in allergic responses and inflammatory diseases. **Clinical Significance:** 1. **Cardiovascular disease:** Dysregulation of NDST2 has been linked to cardiovascular disease, including hypertension and atherosclerosis. 2. **Immune responses:** NDST2 plays a critical role in regulating immune responses, including mast cell-mediated immunity, which is essential for the prevention of allergic diseases and inflammatory disorders. 3. **Tissue homeostasis:** NDST2 is involved in maintaining tissue homeostasis, particularly in the kidney and nervous system. 4. **Cancer:** The role of NDST2 in cancer is complex, with some studies suggesting its involvement in tumor progression and others indicating its potential as a tumor suppressor. In conclusion, NDST2 is a multifunctional enzyme that plays a critical role in heparan sulfate metabolism, regulation of angiotensin levels, and mast cell-mediated immunity. Its dysregulation has been implicated in various diseases, including cardiovascular disease, immune responses, and tissue homeostasis. Further research is necessary to fully elucidate the complexities of NDST2 and its clinical significance.

Genular Protein ID: 3612934949

Symbol: NDST2_HUMAN

Name: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

UniProtKB Accession Codes:

P52849 Q2TB32 Q59H89

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 8 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 4 EMBL 6 Ensembl 2 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9601056

Title: cDNA cloning, genomic organization and chromosomal localization of human heparan glucosaminyl N-deacetylase/N-sulphotransferase-2.

PubMed ID: 9601056

DOI: 10.1042/bj3320303

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10758005

Title: Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns.

PubMed ID: 10758005

DOI: 10.1021/bi992524l

PubMed ID: 12634318

Title: Antibody-based assay for N-deacetylase activity of heparan sulfate/heparin N-deacetylase/N-sulfotransferase (NDST): novel characteristics of NDST-1 and -2.

PubMed ID: 12634318

DOI: 10.1093/glycob/cwg011

PubMed ID: 16343444

Title: Characterization of the N-deacetylase domain from the heparan sulfate N-deacetylase/N-sulfotransferase 2.

PubMed ID: 16343444

DOI: 10.1016/j.bbrc.2005.11.142

PubMed ID: 22660413

Title: Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.

PubMed ID: 22660413

DOI: 10.1038/ncb2502

Sequence Information:

  • Length: 883
  • Mass: 100875
  • Checksum: 457166F8FCB403E1
  • Sequence:
    • MLQLWKVVRP ARQLELHRLI LLLIAFSLGS MGFLAYYVST SPKAKEPLPL PLGDCSSGGA 
AGPGPARPPV PPRPPRPPET ARTEPVVLVF VESAYSQLGQ EIVAILESSR FRYSTELAPG 
RGDMPTLTDN THGRYVLVIY ENLLKYVNLD AWSRELLDRY CVEYGVGIIG FFRAHEHSLL 
SAQLKGFPLF LHSNLGLRDY QVNPSAPLLH LTRPSRLEPG PLPGDDWTIF QSNHSTYEPV 
LLASLRPAEP AVPGPVLRRA RLPTVVQDLG LHDGIQRVLF GHGLSFWLHK LIFVDAVAYL 
TGKRLCLDLD RYILVDIDDI FVGKEGTRMK VADVEALLTT QNKLRTLVPN FTFNLGFSGK 
FYHTGTEEED AGDDMLLKHR KEFWWFPHMW SHMQPHLFHN RSVLADQMRL NKQFALEHGI 
PTDLGYAVAP HHSGVYPIHT QLYEAWKSVW GIQVTSTEEY PHLRPARYRR GFIHNGIMVL 
PRQTCGLFTH TIFYNEYPGG SRELDRSIRG GELFLTVLLN PISIFMTHLS NYGNDRLGLY 
TFESLVRFLQ CWTRLRLQTL PPVPLAQKYF ELFPQERSPL WQNPCDDKRH KDIWSKEKTC 
DRLPKFLIVG PQKTGTTAIH FFLSLHPAVT SSFPSPSTFE EIQFFNSPNY HKGIDWYMDF 
FPVPSNASTD FLFEKSATYF DSEVVPRRGA ALLPRAKIIT VLTNPADRAY SWYQHQRAHG 
DPVALNYTFY QVISASSQTP LALRSLQNRC LVPGYYSTHL QRWLTYYPSG QLLIVDGQEL 
RTNPAASMES IQKFLGITPF LNYTRTLRFD DDKGFWCQGL EGGKTRCLGR SKGRRYPDMD 
TESRLFLTDF FRNHNLELSK LLSRLGQPVP SWLREELQHS SLG

Genular Protein ID: 1375164470

Symbol: S4R438_HUMAN

Name: N/A

UniProtKB Accession Codes:

S4R438

Database IDs:

ARBA 6 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneCards 1 HOGENOM 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSR 2 PeptideAtlas 1 Pfam 4 Proteomes 2 RefSeq 1 SAM 2 SMR 1 SUPFAM 1 UCSC 1 UniPathway 2 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 815
  • Mass: 92872
  • Checksum: FDF2DBF21A8503F5
  • Sequence:
    • MLQLWKVVRP ARQLELHRLI LLLIAFSLGS MGFLAYYVST SPKAKEPLPL PLGDCSSGGA 
AGPGPARPPV PPRPPRPPET ARTEPVVLVF VESAYSQLGQ EIVAILESSR FRYSTELAPG 
RGDMPTLTDN THGRYVLVIY ENLLKYVNLD AWSRELLDRY CVEYGVGIIG FFRAHEHSLL 
SAQLKGFPLF LHSNLGLRDY QVNPSAPLLH LTRPSRLEPG PLPGDDWTIF QSNHSTYEPV 
LLASLRPAEP AVPGPVLRRA RLPTVVQDLG LHDGIQRVLF GHGLSFWLHK LIFVDAVAYL 
TGKRLCLDLD RYILVDIDDI FVGKEGTRMK VADVEALLTT QNKLRTLVPN FTFNLGFSGK 
FYHTGTEEED AGDDMLLKHR KEFWWFPHMW SHMQPHLFHN RSVLADQMRL NKQFALEHGI 
PTDLGYAVAP HHSGVYPIHT QLYEAWKSVW GIQVTSTEEY PHLRPARYRR GFIHNGIMVL 
PRQTCGLFTH TIFYNEYPGG SRELDRSIRG GELFLTVLLN PISIFMTHLS NYGNDRLGLY 
TFESLVRFLQ CWTRLRLQTL PPVPLAQKYF ELFPQERSPL WQNPCDDKRH KDIWSKEKTC 
DRLPKFLIVG PQKTGTTAIH FFLSLHPAVT SSFPSPSTFE EIQFFNSPNY HKGIDWYMDF 
FPVPSNASTD FLFEKSATYF DSEVVPRRGA ALLPRAKIIT VLTNPADRAY SWYQHQRAHG 
DPVALNYTFY QVISASSQTP LALRSLQNRC LVPGYYSTHL QRWLTYYPSG QLLIVDGQEL 
RTNPAASMES IQKFLGLMMI RDFGARDLKV VRLAV

Genular Protein ID: 3324614699

Symbol: B4E139_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E139

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 3 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 3 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 SUPFAM 1 UniPathway 2

Sequence Information:

  • Length: 760
  • Mass: 87573
  • Checksum: F74EEB5AA970271D
  • Sequence:
    • MPTLTDNTHG RYVLVIYENL LKYVNLDAWS RELLDRYCVE YGVGIIGFFR AHEHSLLSAQ 
LKGFPLFLHS NLGLRDYQVN PSAPLLHLTR PSRLEPGPLP GDDWTIFQSN HSTYEPVLLA 
SLRPAEPAVP GPVLRRARLP TVVLDLGLHD GIQRVLFGHG LSFWLHKLIF VDAVAYLTGK 
RLCLDLDRYI LVDIDDIFVG KEGTRMKVAD VEALLTTQNK LRTLVPNFTF NLGFSGKFYH 
TGTEEEDAGD DMLLKHRKEF WWFPHMWSHM QPHLFHNRSV LADQMRLNKQ FALEHGIPTD 
LGYAVAPHHS GVYPIHTQLY EAWKSVWGIQ VTSTEEYPHL RPARYRRGFI HNGIMVLPRQ 
TCGLFTHTIF YNEYPGGSRE LDRSIRGGEL FLTVLLNPIS IFMTHLSNYG NDRLGLYTFE 
SLVRFLQCWT RLRLQTLPPV PLAQKYFELF PQERSPLWQN PCDDKRHKDI WSKEKTCDRL 
PKFLIVGPQK TGTTAIHFFL SLHPAVTSSF PSPSTFEEIQ FFNSPNYHKG IDWYMDFFPV 
PSNASTDFLF EKSATYFDSE VVPRRGAALL PRAKIITVLT NPADRAYSWY QHQRAHGDPV 
ALNYTFYQVI SASSQTPLAL RSLQNRCLVP GYYSTHLQRW LTYYPSGQLL IVDGQELRTN 
PAASMESIQK FLGITPFLNY TRTLRFDDDK GFWCQGLEGG KTRCLGRSKG RRYPDMDTES 
RLFLTDFFRN HNLELSKLLS RLGQPVPSWL REELQHSSLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.