Details for: DGKZ

Gene ID: 8525

Symbol: DGKZ

Ensembl ID: ENSG00000149091

Description: diacylglycerol kinase zeta

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 209.2639
    Cell Significance Index: -32.5500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 107.4934
    Cell Significance Index: -27.2700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 74.9587
    Cell Significance Index: -30.4500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 66.7982
    Cell Significance Index: -34.3600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 52.2486
    Cell Significance Index: -35.0600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 32.2652
    Cell Significance Index: -30.8100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.0407
    Cell Significance Index: -33.3400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.6720
    Cell Significance Index: -35.8500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.2660
    Cell Significance Index: -30.1800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.6162
    Cell Significance Index: -34.0000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.2963
    Cell Significance Index: -13.7800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.8356
    Cell Significance Index: 80.9200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.5146
    Cell Significance Index: 504.4300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.7988
    Cell Significance Index: 1624.2100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.4628
    Cell Significance Index: 98.3600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.4387
    Cell Significance Index: 54.4800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.4315
    Cell Significance Index: 74.5700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.3286
    Cell Significance Index: 144.5100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.2963
    Cell Significance Index: 77.8200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 1.1013
    Cell Significance Index: 29.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0638
    Cell Significance Index: 381.5600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8464
    Cell Significance Index: 24.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7603
    Cell Significance Index: 123.6600
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.6949
    Cell Significance Index: 9.2700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.6425
    Cell Significance Index: 15.6800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5983
    Cell Significance Index: 45.9100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5359
    Cell Significance Index: 370.6300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4951
    Cell Significance Index: 31.9400
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.4863
    Cell Significance Index: 3.7300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4826
    Cell Significance Index: 25.3400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.4453
    Cell Significance Index: 8.2300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4437
    Cell Significance Index: 79.9800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4206
    Cell Significance Index: 83.4700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4109
    Cell Significance Index: 28.4200
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.3994
    Cell Significance Index: 1.0700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3897
    Cell Significance Index: 10.8900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3687
    Cell Significance Index: 36.4700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3485
    Cell Significance Index: 154.0800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3381
    Cell Significance Index: 14.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2674
    Cell Significance Index: 50.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2642
    Cell Significance Index: 32.4800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2247
    Cell Significance Index: 6.0000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2160
    Cell Significance Index: 9.7900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2098
    Cell Significance Index: 28.8100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1736
    Cell Significance Index: 8.1600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1705
    Cell Significance Index: 93.1400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1608
    Cell Significance Index: 3.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1303
    Cell Significance Index: 15.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1253
    Cell Significance Index: 5.8400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1193
    Cell Significance Index: 7.3400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1087
    Cell Significance Index: 3.8200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0580
    Cell Significance Index: 7.5000
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.0499
    Cell Significance Index: 0.3100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0315
    Cell Significance Index: 5.3900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0240
    Cell Significance Index: 1.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0172
    Cell Significance Index: 7.8200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0116
    Cell Significance Index: 0.6000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0085
    Cell Significance Index: 0.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0031
    Cell Significance Index: -5.7500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0034
    Cell Significance Index: -5.1600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0102
    Cell Significance Index: -18.8300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0145
    Cell Significance Index: -19.7700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0313
    Cell Significance Index: -22.9700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0319
    Cell Significance Index: -20.2800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0373
    Cell Significance Index: -27.6300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0379
    Cell Significance Index: -28.7000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0440
    Cell Significance Index: -3.1100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0447
    Cell Significance Index: -0.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0558
    Cell Significance Index: -31.5000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0609
    Cell Significance Index: -38.0600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0698
    Cell Significance Index: -7.1300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0990
    Cell Significance Index: -28.5000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1007
    Cell Significance Index: -2.7400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1083
    Cell Significance Index: -12.6200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1349
    Cell Significance Index: -1.1000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1601
    Cell Significance Index: -23.2700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1671
    Cell Significance Index: -21.4200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1717
    Cell Significance Index: -36.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1957
    Cell Significance Index: -22.4200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2160
    Cell Significance Index: -5.1800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2190
    Cell Significance Index: -4.7500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2807
    Cell Significance Index: -15.7500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2808
    Cell Significance Index: -29.2400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2907
    Cell Significance Index: -6.1700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3143
    Cell Significance Index: -8.0300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3945
    Cell Significance Index: -5.6500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3994
    Cell Significance Index: -31.6300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4159
    Cell Significance Index: -6.1400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4164
    Cell Significance Index: -25.5300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4446
    Cell Significance Index: -7.6200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4502
    Cell Significance Index: -14.4200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4515
    Cell Significance Index: -14.3800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4801
    Cell Significance Index: -6.5500
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.5034
    Cell Significance Index: -4.7900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5090
    Cell Significance Index: -16.6700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5137
    Cell Significance Index: -17.8500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5150
    Cell Significance Index: -10.3400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5225
    Cell Significance Index: -32.9300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.5503
    Cell Significance Index: -11.8900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5512
    Cell Significance Index: -15.8000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DGKZ is a member of the diacylglycerol kinase family, which catalyzes the phosphorylation of diacylglycerol (DAG) to produce phosphatidic acid (PA). This reaction is essential for regulating cellular signaling pathways, including those involved in immune responses. DGKZ is specifically expressed in various cell types, including pyramidal neurons, T cells, monocytes, and neurons, indicating its widespread involvement in immune regulation and cellular signaling. **Pathways and Functions:** DGKZ is involved in several key signaling pathways, including: 1. **G protein-coupled receptor (GPCR) signaling:** DGKZ regulates the downstream signaling events of GPCRs, which are crucial for immune response and cellular signaling. 2. **Negative regulation of T cell receptor signaling:** DGKZ inhibits the activation of T cells, thereby modulating the immune response. 3. **Cell migration and cytoskeleton organization:** DGKZ regulates the cytoskeleton organization and cell migration, essential for immune cell trafficking and tissue homing. 4. **Lipid metabolism:** DGKZ is involved in the regulation of lipid metabolism, including the production of phosphatidic acid, which is essential for cellular signaling. DGKZ's functions are multifaceted, and its dysregulation has been implicated in various diseases, including immune disorders and neurological conditions. **Clinical Significance:** DGKZ's involvement in immune regulation and cellular signaling makes it a promising target for the treatment of various diseases, including: 1. **Autoimmune disorders:** Dysregulation of DGKZ has been implicated in autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 2. **Neurological disorders:** DGKZ's role in lipid metabolism and cellular signaling makes it a potential target for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer:** DGKZ's involvement in cell migration and cytoskeleton organization makes it a potential target for the treatment of cancer. In conclusion, DGKZ is a complex enzyme with multiple functions in cellular signaling and immune regulation. Its dysregulation has been implicated in various diseases, making it a promising target for the development of novel therapeutic strategies. **Future Directions:** Further research is needed to fully understand the mechanisms of DGKZ's functions and its role in disease. Future studies should focus on: 1. **Investigating the specific mechanisms of DGKZ's functions in immune regulation and cellular signaling.** 2. **Developing novel therapeutic strategies targeting DGKZ for the treatment of autoimmune disorders and neurological conditions.** 3. **Exploring the potential of DGKZ as a biomarker for disease diagnosis and prognosis.**

Genular Protein ID: 2781816458

Symbol: DGKZ_HUMAN

Name: Diglyceride kinase zeta

UniProtKB Accession Codes:

Q13574 B7Z2M9 B7Z6M3 E9PPW4 F6UCU9 G3V0F6 J3KNJ6 O00542 Q6ZVG7 Q8IVW9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 7 CDD 2 CORUM 1 CTD 1 ChEBI 90 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 2 EMBL 9 Ensembl 7 ExpressionAtlas 1 GO 24 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 1 RefSeq 7 Rhea 36 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 3 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8626588

Title: Molecular cloning and characterization of a novel human diacylglycerol kinase zeta.

PubMed ID: 8626588

DOI: 10.1074/jbc.271.17.10237

PubMed ID: 9159104

Title: Alternative splicing of the human diacylglycerol kinase zeta gene in muscle.

PubMed ID: 9159104

DOI: 10.1073/pnas.94.11.5519

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9716136

Title: Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta.

PubMed ID: 9716136

DOI: 10.1038/29337

PubMed ID: 11352924

Title: Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions.

PubMed ID: 11352924

DOI: 10.1074/jbc.m104156200

PubMed ID: 11257115

Title: Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism.

PubMed ID: 11257115

DOI: 10.1083/jcb.152.6.1135

PubMed ID: 15544348

Title: The alpha isoform of diacylglycerol kinase exhibits arachidonoyl specificity with alkylacylglycerol.

PubMed ID: 15544348

DOI: 10.1021/bi0484724

PubMed ID: 15157668

Title: Diacylglycerol kinase zeta regulates phosphatidylinositol 4-phosphate 5-kinase Ialpha by a novel mechanism.

PubMed ID: 15157668

DOI: 10.1016/j.cellsig.2004.01.010

PubMed ID: 18004883

Title: Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase.

PubMed ID: 18004883

DOI: 10.1021/bi701584v

PubMed ID: 17351151

Title: Proteomics identification of sorting nexin 27 as a diacylglycerol kinase zeta-associated protein: new diacylglycerol kinase roles in endocytic recycling.

PubMed ID: 17351151

DOI: 10.1074/mcp.m700047-mcp200

PubMed ID: 19744926

Title: Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol.

PubMed ID: 19744926

DOI: 10.1074/jbc.m109.050617

PubMed ID: 22108654

Title: Substrate specificity of diacylglycerol kinase-epsilon and the phosphatidylinositol cycle.

PubMed ID: 22108654

DOI: 10.1016/j.febslet.2011.11.016

PubMed ID: 22627129

Title: Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.

PubMed ID: 22627129

DOI: 10.1016/j.bbrc.2012.05.077

PubMed ID: 23949095

Title: Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 among diacylglycerol kinase isozymes using a new non-radioactive assay method.

PubMed ID: 23949095

DOI: 10.1159/000351849

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 928
  • Mass: 103981
  • Checksum: 7936A979CB3D35AA
  • Sequence:
    • MEPRDGSPEA RSSDSESASA SSSGSERDAG PEPDKAPRRL NKRRFPGLRL FGHRKAITKS 
GLQHLAPPPP TPGAPCSESE RQIRSTVDWS ESATYGEHIW FETNVSGDFC YVGEQYCVAR 
MLKSVSRRKC AACKIVVHTP CIEQLEKINF RCKPSFRESG SRNVREPTFV RHHWVHRRRQ 
DGKCRHCGKG FQQKFTFHSK EIVAISCSWC KQAYHSKVSC FMLQQIEEPC SLGVHAAVVI 
PPTWILRARR PQNTLKASKK KKRASFKRKS SKKGPEEGRW RPFIIRPTPS PLMKPLLVFV 
NPKSGGNQGA KIIQSFLWYL NPRQVFDLSQ GGPKEALEMY RKVHNLRILA CGGDGTVGWI 
LSTLDQLRLK PPPPVAILPL GTGNDLARTL NWGGGYTDEP VSKILSHVEE GNVVQLDRWD 
LHAEPNPEAG PEDRDEGATD RLPLDVFNNY FSLGFDAHVT LEFHESREAN PEKFNSRFRN 
KMFYAGTAFS DFLMGSSKDL AKHIRVVCDG MDLTPKIQDL KPQCVVFLNI PRYCAGTMPW 
GHPGEHHDFE PQRHDDGYLE VIGFTMTSLA ALQVGGHGER LTQCREVVLT TSKAIPVQVD 
GEPCKLAASR IRIALRNQAT MVQKAKRRSA APLHSDQQPV PEQLRIQVSR VSMHDYEALH 
YDKEQLKEAS VPLGTVVVPG DSDLELCRAH IERLQQEPDG AGAKSPTCQK LSPKWCFLDA 
TTASRFYRID RAQEHLNYVT EIAQDEIYIL DPELLGASAR PDLPTPTSPL PTSPCSPTPR 
SLQGDAAPPQ GEELIEAAKR NDFCKLQELH RAGGDLMHRD EQSRTLLHHA VSTGSKDVVR 
YLLDHAPPEI LDAVEENGET CLHQAAALGQ RTICHYIVEA GASLMKTDQQ GDTPRQRAEK 
AQDTELAAYL ENRQHYQMIQ REDQETAV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.