Details for: API5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 198.1417
Cell Significance Index: -30.8200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 130.6165
Cell Significance Index: -33.1300 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 85.8483
Cell Significance Index: -35.3700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 74.9895
Cell Significance Index: -30.4700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 74.6310
Cell Significance Index: -35.2400 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 67.0995
Cell Significance Index: -34.5200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 32.1134
Cell Significance Index: -30.6600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 28.4033
Cell Significance Index: -35.0200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 11.7513
Cell Significance Index: -31.4800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 10.3615
Cell Significance Index: -31.8300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.1357
Cell Significance Index: -36.0500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.0159
Cell Significance Index: -15.3600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 4.4796
Cell Significance Index: 443.1300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.8924
Cell Significance Index: 1708.6600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.7007
Cell Significance Index: 102.1000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.6894
Cell Significance Index: 23.0500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.3931
Cell Significance Index: 279.4500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.3275
Cell Significance Index: 215.9100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.0389
Cell Significance Index: 27.7400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9292
Cell Significance Index: 184.4100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.8078
Cell Significance Index: 45.3300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.7141
Cell Significance Index: 128.7300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.6852
Cell Significance Index: 84.2500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5714
Cell Significance Index: 204.9400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.5125
Cell Significance Index: 35.4400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.4916
Cell Significance Index: 57.9700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.4752
Cell Significance Index: 13.2800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4429
Cell Significance Index: 241.8800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.4317
Cell Significance Index: 20.1300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4247
Cell Significance Index: 187.7800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.3833
Cell Significance Index: 25.7700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3462
Cell Significance Index: 7.5000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3363
Cell Significance Index: 46.1800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3178
Cell Significance Index: 20.0300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2949
Cell Significance Index: 13.8600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2734
Cell Significance Index: 14.2000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.2400
Cell Significance Index: 18.4200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.2216
Cell Significance Index: 9.8000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2085
Cell Significance Index: 12.8200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.1947
Cell Significance Index: 10.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1936
Cell Significance Index: 36.8500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.1827
Cell Significance Index: 6.9200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1821
Cell Significance Index: 31.1000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1649
Cell Significance Index: 11.6700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0867
Cell Significance Index: 3.9300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0753
Cell Significance Index: 141.8100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.0734
Cell Significance Index: 2.5500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0554
Cell Significance Index: 0.9500 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0520
Cell Significance Index: 6.7200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0506
Cell Significance Index: 1.3300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0428
Cell Significance Index: 27.1800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0337
Cell Significance Index: 0.9700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0334
Cell Significance Index: 2.4900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.0256
Cell Significance Index: 0.7300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0240
Cell Significance Index: 3.0800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0176
Cell Significance Index: 27.1600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0156
Cell Significance Index: 28.8600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0137
Cell Significance Index: 0.7200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0128
Cell Significance Index: 5.8000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0048
Cell Significance Index: 0.1700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0043
Cell Significance Index: -3.1700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0076
Cell Significance Index: -10.3200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0079
Cell Significance Index: -5.7900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0093
Cell Significance Index: -5.7800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.0153
Cell Significance Index: -0.4500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0189
Cell Significance Index: -14.2700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0277
Cell Significance Index: -1.7900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0378
Cell Significance Index: -21.2900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0406
Cell Significance Index: -1.1100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0427
Cell Significance Index: -0.7200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0432
Cell Significance Index: -4.9300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0495
Cell Significance Index: -5.0600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0534
Cell Significance Index: -1.4300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0768
Cell Significance Index: -16.1700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1020
Cell Significance Index: -11.8900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1024
Cell Significance Index: -2.1800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1082
Cell Significance Index: -15.7300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1082
Cell Significance Index: -31.1400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1905
Cell Significance Index: -21.8200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1973
Cell Significance Index: -3.8500 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.2198
Cell Significance Index: -2.6200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2440
Cell Significance Index: -7.0000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2836
Cell Significance Index: -29.5300 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2844
Cell Significance Index: -6.5700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2893
Cell Significance Index: -6.9400 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3147
Cell Significance Index: -6.8900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3212
Cell Significance Index: -25.4400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.3616
Cell Significance Index: -3.3300 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.4144
Cell Significance Index: -6.9800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4738
Cell Significance Index: -29.0500 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.5048
Cell Significance Index: -12.9000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6251
Cell Significance Index: -19.9100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.6341
Cell Significance Index: -20.3100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6695
Cell Significance Index: -21.9200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.6700
Cell Significance Index: -14.2200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.6722
Cell Significance Index: -14.0700 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.6850
Cell Significance Index: -10.1100 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.6945
Cell Significance Index: -14.8500 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.7261
Cell Significance Index: -10.7200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.7337
Cell Significance Index: -18.8600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2078202284
Symbol: API5_HUMAN
Name: Antiapoptosis clone 11 protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9307294
Title: AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal.
PubMed ID: 9307294
PubMed ID: 10393420
Title: Molecular cloning and fine mapping of API5L1, a novel human gene strongly related to an antiapoptotic gene.
PubMed ID: 10393420
DOI: 10.1159/000015247
PubMed ID: 11075807
Title: FIF [fibroblast growth factor-2 (FGF-2)-interacting-factor], a nuclear putatively antiapoptotic factor, interacts specifically with FGF-2.
PubMed ID: 11075807
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8889549
Title: Generation and analysis of 280,000 human expressed sequence tags.
PubMed ID: 8889549
DOI: 10.1101/gr.6.9.807
PubMed ID: 10780674
Title: AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis.
PubMed ID: 10780674
PubMed ID: 11557113
Title: Expression of the antiapoptosis gene, AAC-11, as a prognosis marker in non-small cell lung cancer.
PubMed ID: 11557113
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17112319
Title: Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.
PubMed ID: 17112319
PubMed ID: 17827341
Title: The antiapoptotic protein Api5 and its partner, high molecular weight FGF2, are up-regulated in B cell chronic lymphoid leukemia.
PubMed ID: 17827341
DOI: 10.1189/jlb.0607425
PubMed ID: 19387494
Title: The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation.
PubMed ID: 19387494
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 22334682
Title: Helical repeat structure of apoptosis inhibitor 5 reveals protein-protein interaction modules.
PubMed ID: 22334682
Sequence Information:
- Length: 524
- Mass: 59005
- Checksum: A2EA6BE4D8318BB9
- Sequence:
MPTVEELYRN YGILADATEQ VGQHKDAYQV ILDGVKGGTK EKRLAAQFIP KFFKHFPELA DSAINAQLDL CEDEDVSIRR QAIKELPQFA TGENLPRVAD ILTQLLQTDD SAEFNLVNNA LLSIFKMDAK GTLGGLFSQI LQGEDIVRER AIKFLSTKLK TLPDEVLTKE VEELILTESK KVLEDVTGEE FVLFMKILSG LKSLQTVSGR QQLVELVAEQ ADLEQTFNPS DPDCVDRLLQ CTRQAVPLFS KNVHSTRFVT YFCEQVLPNL GTLTTPVEGL DIQLEVLKLL AEMSSFCGDM EKLETNLRKL FDKLLEYMPL PPEEAENGEN AGNEEPKLQF SYVECLLYSF HQLGRKLPDF LTAKLNAEKL KDFKIRLQYF ARGLQVYIRQ LRLALQGKTG EALKTEENKI KVVALKITNN INVLIKDLFH IPPSYKSTVT LSWKPVQKVE IGQKRASEDT TSGSPPKKSS AGPKRDARQI YNPPSGKYSS NLGNFNYEQR GAFRGSRGGR GWGTRGNRSR GRLY
Genular Protein ID: 2661738722
Symbol: B4DDR3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 331
- Mass: 37508
- Checksum: D6E3EC7C3DDAFCB9
- Sequence:
MPTVEELYRN YGILADATEQ VGQHKDAYQV ILDGVKGGTK EKRLAAQFIP KFFKHFPELA DSAINAQLDL CEDEDVSIRR QAIKELPQFA TGENLPRVAD ILTQLLQTDD SAEFNLVNNA LLSIFKMEKL ETNLRKLFDK LLEYMPLPPE EAENGENAGN EEPKLQFSYV ECLLYSFHQL GRKLPDFLTA KLNAEKLKDF KIRLQYFARG LQVYIRQLRL ALQGKTGEAL KTEENKIKVV ALKITNNINV LIKDLFHIPP SYKSTVTLSW KPVQKVEIGQ KRASEDTTSG SPPKKSSAGP KRDARQIYNP PSGKYSSNLG NFNYERSLQG K
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.