Details for: AP3B1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 385.3220
Cell Significance Index: -59.9400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 230.3234
Cell Significance Index: -58.4200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 131.7392
Cell Significance Index: -53.5200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 116.8579
Cell Significance Index: -60.1100 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 94.2592
Cell Significance Index: -63.2500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 56.1198
Cell Significance Index: -53.5800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 50.2492
Cell Significance Index: -61.9600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 21.9664
Cell Significance Index: -58.8500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 18.1152
Cell Significance Index: -55.6400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 17.2211
Cell Significance Index: -37.6900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 15.7981
Cell Significance Index: -62.3400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.7178
Cell Significance Index: 152.5100 - Cell Name: preadipocyte (CL0002334)
Fold Change: 2.5332
Cell Significance Index: 49.4400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.1711
Cell Significance Index: 430.8600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.6511
Cell Significance Index: 331.2100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.4490
Cell Significance Index: 19.7700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.3635
Cell Significance Index: 29.1500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.2576
Cell Significance Index: 96.5100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.1353
Cell Significance Index: 30.3200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.0584
Cell Significance Index: 29.5800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.8346
Cell Significance Index: 577.2700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.8225
Cell Significance Index: 148.2800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.7177
Cell Significance Index: 257.4300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.7167
Cell Significance Index: 88.1200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.6569
Cell Significance Index: 45.4300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5697
Cell Significance Index: 16.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.5322
Cell Significance Index: 11.5300 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.5003
Cell Significance Index: 4.0800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4336
Cell Significance Index: 391.5200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.4283
Cell Significance Index: 6.1600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.4116
Cell Significance Index: 19.1900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.3566
Cell Significance Index: 23.9800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3553
Cell Significance Index: 194.0600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.2854
Cell Significance Index: 12.6300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2557
Cell Significance Index: 35.1200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2383
Cell Significance Index: 105.3400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2126
Cell Significance Index: 400.2800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1952
Cell Significance Index: 31.7500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1833
Cell Significance Index: 6.4400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.1680
Cell Significance Index: 6.3600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1576
Cell Significance Index: 242.6800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1560
Cell Significance Index: 287.7800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1258
Cell Significance Index: 57.1000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1232
Cell Significance Index: 78.2300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1088
Cell Significance Index: 6.6900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0840
Cell Significance Index: 114.2100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0716
Cell Significance Index: 8.4400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0698
Cell Significance Index: 13.2800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0570
Cell Significance Index: 9.7300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0523
Cell Significance Index: 2.3700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0242
Cell Significance Index: 2.3900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0066
Cell Significance Index: -4.8400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0111
Cell Significance Index: -0.1900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0320
Cell Significance Index: -1.6200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0397
Cell Significance Index: -1.0200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0406
Cell Significance Index: -30.0900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0490
Cell Significance Index: -30.5900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0499
Cell Significance Index: -7.2500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0661
Cell Significance Index: -50.0400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0735
Cell Significance Index: -41.4500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0932
Cell Significance Index: -6.0100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0938
Cell Significance Index: -4.8800 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.0940
Cell Significance Index: -1.3500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1166
Cell Significance Index: -5.4800 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.1290
Cell Significance Index: -2.0700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1364
Cell Significance Index: -13.9300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1709
Cell Significance Index: -36.0000 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1806
Cell Significance Index: -23.1500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1879
Cell Significance Index: -54.0700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2192
Cell Significance Index: -11.4200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2727
Cell Significance Index: -7.3100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3032
Cell Significance Index: -39.1700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3759
Cell Significance Index: -43.8100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3777
Cell Significance Index: -26.7100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3782
Cell Significance Index: -43.3300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3977
Cell Significance Index: -41.4100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.4686
Cell Significance Index: -9.9800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.5054
Cell Significance Index: -54.9700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.5368
Cell Significance Index: -40.0100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5608
Cell Significance Index: -64.0200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.5663
Cell Significance Index: -5.2200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.5757
Cell Significance Index: -14.3900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6216
Cell Significance Index: -49.2300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.6505
Cell Significance Index: -3.9300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7766
Cell Significance Index: -47.6100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.8203
Cell Significance Index: -51.7000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.8646
Cell Significance Index: -12.7700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.9077
Cell Significance Index: -47.6600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.9220
Cell Significance Index: -32.0400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.9949
Cell Significance Index: -28.5200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.0023
Cell Significance Index: -16.7800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -1.0150
Cell Significance Index: -27.1500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -1.0416
Cell Significance Index: -30.5900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -1.0832
Cell Significance Index: -30.9100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -1.0889
Cell Significance Index: -29.6400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -1.1062
Cell Significance Index: -26.5300 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -1.1241
Cell Significance Index: -18.9400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.1430
Cell Significance Index: -16.8700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -1.1783
Cell Significance Index: -25.8000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.2864
Cell Significance Index: -40.9700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 572145882
Symbol: AP3B1_HUMAN
Name: AP-3 complex subunit beta-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9151686
Title: Characterization of the adaptor-related protein complex, AP-3.
PubMed ID: 9151686
PubMed ID: 9182526
Title: Beta3A-adaptin, a subunit of the adaptor-like complex AP-3.
PubMed ID: 9182526
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 19934039
Title: Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release.
PubMed ID: 19934039
PubMed ID: 10024875
Title: Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor.
PubMed ID: 10024875
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 1094
- Mass: 121320
- Checksum: AC683CE18EF90555
- Sequence:
MSSNSFPYNE QSGGGEATEL GQEATSTISP SGAFGLFSSD LKKNEDLKQM LESNKDSAKL DAMKRIVGMI AKGKNASELF PAVVKNVASK NIEIKKLVYV YLVRYAEEQQ DLALLSISTF QRALKDPNQL IRASALRVLS SIRVPIIVPI MMLAIKEASA DLSPYVRKNA AHAIQKLYSL DPEQKEMLIE VIEKLLKDKS TLVAGSVVMA FEEVCPDRID LIHKNYRKLC NLLVDVEEWG QVVIIHMLTR YARTQFVSPW KEGDELEDNG KNFYESDDDQ KEKTDKKKKP YTMDPDHRLL IRNTKPLLQS RNAAVVMAVA QLYWHISPKS EAGIISKSLV RLLRSNREVQ YIVLQNIATM SIQRKGMFEP YLKSFYVRST DPTMIKTLKL EILTNLANEA NISTLLREFQ TYVKSQDKQF AAATIQTIGR CATNILEVTD TCLNGLVCLL SNRDEIVVAE SVVVIKKLLQ MQPAQHGEII KHMAKLLDSI TVPVARASIL WLIGENCERV PKIAPDVLRK MAKSFTSEDD LVKLQILNLG AKLYLTNSKQ TKLLTQYILN LGKYDQNYDI RDRTRFIRQL IVPNVKSGAL SKYAKKIFLA QKPAPLLESP FKDRDHFQLG TLSHTLNIKA TGYLELSNWP EVAPDPSVRN VEVIELAKEW TPAGKAKQEN SAKKFYSESE EEEDSSDSSS DSESESGSES GEQGESGEEG DSNEDSSEDS SSEQDSESGR ESGLENKRTA KRNSKAKGKS DSEDGEKENE KSKTSDSSND ESSSIEDSSS DSESESEPES ESESRRVTKE KEKKTKQDRT PLTKDVSLLD LDDFNPVSTP VALPTPALSP SLMADLEGLH LSTSSSVISV STPAFVPTKT HVLLHRMSGK GLAAHYFFPR QPCIFGDKMV SIQITLNNTT DRKIENIHIG EKKLPIGMKM HVFNPIDSLE PEGSITVSMG IDFCDSTQTA SFQLCTKDDC FNVNIQPPVG ELLLPVAMSE KDFKKEQGVL TGMNETSAVI IAAPQNFTPS VIFQKVVNVA NVGAVPSGQD NIHRFAAKTV HSGSLMLVTV ELKEGSTAQL IINTEKTVIG SVLLRELKPV LSQG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.