Details for: EIF3C

Gene ID: 8663

Symbol: EIF3C

Ensembl ID: ENSG00000184110

Description: eukaryotic translation initiation factor 3 subunit C

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 67.3116
    Cell Significance Index: -10.4700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 41.4756
    Cell Significance Index: -10.5200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.0433
    Cell Significance Index: -11.1500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.1436
    Cell Significance Index: -11.1000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.8586
    Cell Significance Index: -11.2800
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 2.7826
    Cell Significance Index: 17.2200
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.7456
    Cell Significance Index: 10.4600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.6311
    Cell Significance Index: -5.0100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.5185
    Cell Significance Index: 829.3000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7636
    Cell Significance Index: 22.0000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7386
    Cell Significance Index: 73.0700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5752
    Cell Significance Index: 26.0700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5129
    Cell Significance Index: 463.1400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4702
    Cell Significance Index: 28.2300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4293
    Cell Significance Index: 46.6900
  • Cell Name: glioblast (CL0000030)
    Fold Change: 0.4093
    Cell Significance Index: 2.5700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3890
    Cell Significance Index: 63.2700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3471
    Cell Significance Index: 7.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3132
    Cell Significance Index: 16.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2104
    Cell Significance Index: 14.5500
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: 0.2090
    Cell Significance Index: 1.9000
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.1961
    Cell Significance Index: 2.7500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1694
    Cell Significance Index: 4.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1574
    Cell Significance Index: 9.9200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1498
    Cell Significance Index: 20.5700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1087
    Cell Significance Index: 3.8200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1080
    Cell Significance Index: 13.2800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0941
    Cell Significance Index: 6.0700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0876
    Cell Significance Index: 15.7900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0805
    Cell Significance Index: 16.1500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0770
    Cell Significance Index: 1.6400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0731
    Cell Significance Index: 13.9200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0725
    Cell Significance Index: 26.0100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0704
    Cell Significance Index: 31.1300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0546
    Cell Significance Index: 10.8400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0510
    Cell Significance Index: 3.9200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0492
    Cell Significance Index: 1.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0448
    Cell Significance Index: 2.0900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0341
    Cell Significance Index: 4.0200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0276
    Cell Significance Index: 1.3000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0225
    Cell Significance Index: 1.5900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0185
    Cell Significance Index: 2.3700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0172
    Cell Significance Index: 2.2200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0164
    Cell Significance Index: 1.2200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0048
    Cell Significance Index: 0.1000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0036
    Cell Significance Index: 1.0300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0003
    Cell Significance Index: 0.0200
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0051
    Cell Significance Index: -0.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0058
    Cell Significance Index: -10.9500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0077
    Cell Significance Index: -1.3200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0077
    Cell Significance Index: -14.2400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0079
    Cell Significance Index: -5.7600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0091
    Cell Significance Index: -13.9600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0104
    Cell Significance Index: -14.1700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0105
    Cell Significance Index: -7.9700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0119
    Cell Significance Index: -0.2500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0128
    Cell Significance Index: -9.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0157
    Cell Significance Index: -9.9700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0193
    Cell Significance Index: -10.8600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0197
    Cell Significance Index: -12.2900
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: -0.0221
    Cell Significance Index: -0.1900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0227
    Cell Significance Index: -0.3800
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.0249
    Cell Significance Index: -0.2600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0264
    Cell Significance Index: -2.7000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0287
    Cell Significance Index: -0.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0310
    Cell Significance Index: -14.0500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0419
    Cell Significance Index: -4.8800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0506
    Cell Significance Index: -0.6900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0525
    Cell Significance Index: -6.0100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0565
    Cell Significance Index: -1.5800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0591
    Cell Significance Index: -12.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0687
    Cell Significance Index: -9.9800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0699
    Cell Significance Index: -2.0100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0731
    Cell Significance Index: -2.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0775
    Cell Significance Index: -4.7500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0781
    Cell Significance Index: -4.3800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0883
    Cell Significance Index: -0.9600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0928
    Cell Significance Index: -2.4400
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0938
    Cell Significance Index: -0.6100
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.1054
    Cell Significance Index: -1.7000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1061
    Cell Significance Index: -1.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1073
    Cell Significance Index: -11.1700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1119
    Cell Significance Index: -3.8900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1240
    Cell Significance Index: -9.8200
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1326
    Cell Significance Index: -1.9000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1370
    Cell Significance Index: -7.2000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.1500
    Cell Significance Index: -3.6600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1551
    Cell Significance Index: -10.4300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1609
    Cell Significance Index: -9.8900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1758
    Cell Significance Index: -4.5200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1868
    Cell Significance Index: -5.4900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1942
    Cell Significance Index: -7.9600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2052
    Cell Significance Index: -5.4800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2096
    Cell Significance Index: -5.3600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2168
    Cell Significance Index: -3.2700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2194
    Cell Significance Index: -4.0600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2209
    Cell Significance Index: -2.5100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2212
    Cell Significance Index: -2.2900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2333
    Cell Significance Index: -10.3200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2379
    Cell Significance Index: -6.3700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EIF3C is a conserved subunit of the eIF3 complex, which is a heterotrimeric complex composed of three subunits: eIF3a, eIF3b, and eIF3c. EIF3C is highly expressed in various cell types, including skeletal muscle satellite cells, basal cells of epithelial tissues, and eukaryotic cells in general. Its expression is also significant in specific cell types, such as B-1 B cells and pulmonary ionocytes. **Pathways and Functions:** EIF3C participates in several key pathways involved in translation initiation, including: 1. **Cap-dependent translation initiation:** EIF3C binds to the cap-binding complex and eIFs, facilitating the recruitment of the 40S ribosomal subunit and the initiation of translation. 2. **Formation of the 43S preinitiation complex:** EIF3C is essential for the assembly of the 43S complex, which is the preinitiation complex that binds to mRNA and recruits the 40S ribosomal subunit. 3. **GTP hydrolysis and joining of the 60S ribosomal subunit:** EIF3C plays a role in the hydrolysis of GTP and the joining of the 60S ribosomal subunit to the 40S subunit, which is necessary for the completion of translation. 4. **Translational silencing of ceruloplasmin expression:** EIF3C has been implicated in the translational silencing of ceruloplasmin expression, which is a key regulator of iron metabolism. **Clinical Significance:** EIF3C has been implicated in various diseases and disorders, including: 1. **Muscular dystrophy:** EIF3C has been shown to be involved in the regulation of muscle cell growth and differentiation, and its dysregulation has been implicated in muscular dystrophy. 2. **Cancer:** EIF3C has been shown to play a role in the regulation of protein synthesis in cancer cells, and its dysregulation has been implicated in various types of cancer. 3. **Neurological disorders:** EIF3C has been implicated in the regulation of protein synthesis in neuronal cells, and its dysregulation has been implicated in neurological disorders such as Alzheimer's disease and Parkinson's disease. In conclusion, EIF3C is a crucial component of the eIF3 complex, which plays a key role in the initiation of protein synthesis in eukaryotic cells. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of EIF3C in maintaining cellular homeostasis and promoting normal cellular function.

Genular Protein ID: 982696027

Symbol: EIF3C_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q99613 A8K7Z0 B2RXG3 B4E1D5 H3BRV0 O00215 Q9BW98

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 EMDB 11 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 6 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8995409

Title: Conservation and diversity of eukaryotic translation initiation factor eIF3.

PubMed ID: 8995409

DOI: 10.1074/jbc.272.2.1101

PubMed ID: 10493829

Title: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

PubMed ID: 10493829

DOI: 10.1006/geno.1999.5927

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14519125

Title: Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor eIF3.

PubMed ID: 14519125

DOI: 10.1046/j.1432-1033.2003.03807.x

PubMed ID: 16286006

Title: mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.

PubMed ID: 16286006

DOI: 10.1016/j.cell.2005.10.024

PubMed ID: 15703437

Title: Binding of eukaryotic initiation factor 3 to ribosomal 40S subunits and its role in ribosomal dissociation and anti-association.

PubMed ID: 15703437

DOI: 10.1261/rna.7215305

PubMed ID: 16023166

Title: Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54.

PubMed ID: 16023166

DOI: 10.1016/j.virol.2005.06.011

PubMed ID: 16766523

Title: Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit.

PubMed ID: 16766523

DOI: 10.1074/jbc.m605418200

PubMed ID: 16973618

Title: Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56.

PubMed ID: 16973618

DOI: 10.1074/jbc.m605771200

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 17468741

Title: Human INT6/eIF3e is required for nonsense-mediated mRNA decay.

PubMed ID: 17468741

DOI: 10.1038/sj.embor.7400955

PubMed ID: 17322308

Title: Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

PubMed ID: 17322308

DOI: 10.1074/mcp.m600399-mcp200

PubMed ID: 18599441

Title: Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

PubMed ID: 18599441

DOI: 10.1073/pnas.0801313105

PubMed ID: 19541769

Title: IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR.

PubMed ID: 19541769

DOI: 10.1261/rna.1578409

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23145062

Title: Human ALKBH4 interacts with proteins associated with transcription.

PubMed ID: 23145062

DOI: 10.1371/journal.pone.0049045

PubMed ID: 25849773

Title: eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.

PubMed ID: 25849773

DOI: 10.1038/nature14267

PubMed ID: 27462815

Title: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.

PubMed ID: 27462815

DOI: 10.1038/nature18954

PubMed ID: 34260931

Title: Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism.

PubMed ID: 34260931

DOI: 10.1016/j.celrep.2021.109376

PubMed ID: 16322461

Title: Structural roles for human translation factor eIF3 in initiation of protein synthesis.

PubMed ID: 16322461

DOI: 10.1126/science.1118977

Sequence Information:

  • Length: 913
  • Mass: 105344
  • Checksum: CE5029F4EB51C1AA
  • Sequence:
    • MSRFFTTGSD SESESSLSGE ELVTKPVGGN YGKQPLLLSE DEEDTKRVVR SAKDKRFEEL 
TNLIRTIRNA MKIRDVTKCL EEFELLGKAY GKAKSIVDKE GVPRFYIRIL ADLEDYLNEL 
WEDKEGKKKM NKNNAKALST LRQKIRKYNR DFESHITSYK QNPEQSADED AEKNEEDSEG 
SSDEDEDEDG VSAATFLKKK SEAPSGESRK FLKKMDDEDE DSEDSEDDED WDTGSTSSDS 
DSEEEEGKQT ALASRFLKKA PTTDEDKKAA EKKREDKAKK KHDRKSKRLD EEEEDNEGGE 
WERVRGGVPL VKEKPKMFAK GTEITHAVVI KKLNEILQAR GKKGTDRAAQ IELLQLLVQI 
AAENNLGEGV IVKIKFNIIA SLYDYNPNLA TYMKPEMWGK CLDCINELMD ILFANPNIFV 
GENILEESEN LHNADQPLRV RGCILTLVER MDEEFTKIMQ NTDPHSQEYV EHLKDEAQVC 
AIIERVQRYL EEKGTTEEVC RIYLLRILHT YYKFDYKAHQ RQLTPPEGSS KSEQDQAENE 
GEDSAVLMER LCKYIYAKDR TDRIRTCAIL CHIYHHALHS RWYQARDLML MSHLQDNIQH 
ADPPVQILYN RTMVQLGICA FRQGLTKDAH NALLDIQSSG RAKELLGQGL LLRSLQERNQ 
EQEKVERRRQ VPFHLHINLE LLECVYLVSA MLLEIPYMAA HESDARRRMI SKQFHHQLRV 
GERQPLLGPP ESMREHVVAA SKAMKMGDWK TCHSFIINEK MNGKVWDLFP EADKVRTMLV 
RKIQEESLRT YLFTYSSVYD SISMETLSDM FELDLPTVHS IISKMIINEE LMASLDQPTQ 
TVVMHRTEPT AQQNLALQLA EKLGSLVENN ERVFDHKQGT YGGYFRDQKD GYRKNEGYMR 
RGGYRQQQSQ TAY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.