Details for: MTMR1

Gene ID: 8776

Symbol: MTMR1

Ensembl ID: ENSG00000063601

Description: myotubularin related protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 151.0815
    Cell Significance Index: -23.5000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 91.3093
    Cell Significance Index: -23.1600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 49.2299
    Cell Significance Index: -20.0000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 38.7022
    Cell Significance Index: -25.9700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.0528
    Cell Significance Index: -20.1000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.1815
    Cell Significance Index: -23.6500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.5152
    Cell Significance Index: -25.4900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.4260
    Cell Significance Index: -25.8800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.9223
    Cell Significance Index: -15.1500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.0339
    Cell Significance Index: -23.8100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.7671
    Cell Significance Index: 336.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7535
    Cell Significance Index: 351.7600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.6368
    Cell Significance Index: 110.0600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.6367
    Cell Significance Index: 22.3300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.4116
    Cell Significance Index: 39.4500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.2773
    Cell Significance Index: 36.4500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.1511
    Cell Significance Index: 43.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.9914
    Cell Significance Index: 43.8500
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.9463
    Cell Significance Index: 8.4000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9170
    Cell Significance Index: 90.7100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9021
    Cell Significance Index: 323.5800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7388
    Cell Significance Index: 667.0700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6475
    Cell Significance Index: 128.5000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.5827
    Cell Significance Index: 32.7000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.5734
    Cell Significance Index: 14.7400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.5489
    Cell Significance Index: 13.7200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5244
    Cell Significance Index: 40.2500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4606
    Cell Significance Index: 74.9100
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.4434
    Cell Significance Index: 6.2000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4407
    Cell Significance Index: 47.9400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.3807
    Cell Significance Index: 44.3700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3786
    Cell Significance Index: 261.8500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3720
    Cell Significance Index: 7.2600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3488
    Cell Significance Index: 21.4400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3268
    Cell Significance Index: 19.6200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2779
    Cell Significance Index: 6.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2726
    Cell Significance Index: 33.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2231
    Cell Significance Index: 11.5900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2079
    Cell Significance Index: 37.4900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1835
    Cell Significance Index: 4.4000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1745
    Cell Significance Index: 12.0700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1621
    Cell Significance Index: 4.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1212
    Cell Significance Index: 3.3000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1103
    Cell Significance Index: 1.8900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0996
    Cell Significance Index: 44.0300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0962
    Cell Significance Index: 4.3600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0932
    Cell Significance Index: 175.4100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0851
    Cell Significance Index: 38.6300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0729
    Cell Significance Index: 2.5600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0709
    Cell Significance Index: 109.2100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0661
    Cell Significance Index: 42.0000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0579
    Cell Significance Index: 31.6400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0465
    Cell Significance Index: 85.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0329
    Cell Significance Index: 44.6900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0240
    Cell Significance Index: 0.6400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0209
    Cell Significance Index: 1.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0126
    Cell Significance Index: -1.4900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0172
    Cell Significance Index: -2.5000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0180
    Cell Significance Index: -0.8500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0224
    Cell Significance Index: -16.5800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0230
    Cell Significance Index: -16.8800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0245
    Cell Significance Index: -4.1800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0274
    Cell Significance Index: -0.3900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0275
    Cell Significance Index: -20.8500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0410
    Cell Significance Index: -23.1200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0429
    Cell Significance Index: -26.7800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0483
    Cell Significance Index: -2.2500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0669
    Cell Significance Index: -7.6700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0680
    Cell Significance Index: -9.3400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0845
    Cell Significance Index: -24.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1121
    Cell Significance Index: -11.6700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1170
    Cell Significance Index: -15.1100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1248
    Cell Significance Index: -26.2800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1257
    Cell Significance Index: -12.8400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1259
    Cell Significance Index: -6.5600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1293
    Cell Significance Index: -2.7500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1560
    Cell Significance Index: -3.3400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1670
    Cell Significance Index: -21.4100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1861
    Cell Significance Index: -13.1600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1977
    Cell Significance Index: -4.2100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1995
    Cell Significance Index: -3.4500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2043
    Cell Significance Index: -13.1800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2048
    Cell Significance Index: -6.5600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2085
    Cell Significance Index: -12.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2253
    Cell Significance Index: -16.7900
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.2367
    Cell Significance Index: -3.0700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2424
    Cell Significance Index: -7.7200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2446
    Cell Significance Index: -4.9100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2487
    Cell Significance Index: -5.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2711
    Cell Significance Index: -21.4700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2723
    Cell Significance Index: -4.0200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.2830
    Cell Significance Index: -3.5100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2999
    Cell Significance Index: -5.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3074
    Cell Significance Index: -16.1400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3107
    Cell Significance Index: -7.5800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3134
    Cell Significance Index: -10.2600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3364
    Cell Significance Index: -5.0700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.3740
    Cell Significance Index: -5.3700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3851
    Cell Significance Index: -8.3200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3938
    Cell Significance Index: -4.9100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MTMR1 is a phosphatase enzyme that specifically hydrolyzes phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) and phosphatidylinositol 3-phosphate (PI3P), two phospholipids that play critical roles in cell signaling and membrane trafficking. MTMR1 is a homodimeric protein, consisting of two identical subunits, which are involved in the regulation of PI3P phosphatase activity. The enzyme is also involved in the regulation of Rho GTPases, which are small GTP-binding proteins that play key roles in cell signaling, cytoskeleton organization, and membrane trafficking. **Pathways and Functions** MTMR1 is involved in various cellular processes, including: 1. **Regulation of Rho GTPases**: MTMR1 regulates the activity of Rho GTPases, which are involved in cell signaling, cytoskeleton organization, and membrane trafficking. 2. **Phosphatidylinositol biosynthesis**: MTMR1 is involved in the regulation of phosphatidylinositol biosynthesis, which is critical for cell signaling and membrane trafficking. 3. **Phospholipid metabolism**: MTMR1 regulates the metabolism of phospholipids, including PI(3,5)P2 and PI3P, which are involved in cell signaling and membrane trafficking. 4. **Cytoskeleton organization**: MTMR1 regulates the activity of Rho GTPases, which are involved in cytoskeleton organization and cell migration. 5. **Neurotransmission**: MTMR1 is involved in the regulation of neurotransmitter release and synaptic plasticity in neurons. **Clinical Significance** Dysregulation of MTMR1 has been implicated in various diseases, including: 1. **Muscular dystrophy**: Mutations in the MTMR1 gene have been associated with myotubular myopathy, a type of muscular dystrophy. 2. **Neurodegenerative diseases**: Dysregulation of MTMR1 has been implicated in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. 3. **Cancer**: MTMR1 is involved in the regulation of cell signaling and membrane trafficking, and dysregulation of MTMR1 has been implicated in cancer development and progression. 4. **Cardiovascular disease**: MTMR1 is involved in the regulation of cell signaling and membrane trafficking, and dysregulation of MTMR1 has been implicated in cardiovascular disease. In conclusion, MTMR1 is a critical phosphatase enzyme that plays a key role in regulating the activity of small GTPases, phosphatidylinositol biosynthesis, and phospholipid metabolism. Dysregulation of MTMR1 has been implicated in various diseases, highlighting the importance of further research into the role of MTMR1 in human health and disease.

Genular Protein ID: 3314814200

Symbol: MTMR1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q13613 A0A024RC07 Q9UBX6 Q9UEM0 Q9UQD5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 27 ChiTaRS 1 DEPOD 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 6 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 Rhea 3 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9828128

Title: Genomic organization of a 225-kb region in Xq28 containing the gene for X-linked myotubular myopathy (MTM1) and a related gene (MTMR1).

PubMed ID: 9828128

DOI: 10.1006/geno.1998.5560

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 9736772

Title: Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

PubMed ID: 9736772

DOI: 10.1093/hmg/7.11.1703

PubMed ID: 8640223

Title: A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast.

PubMed ID: 8640223

DOI: 10.1038/ng0696-175

PubMed ID: 11733541

Title: Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease.

PubMed ID: 11733541

DOI: 10.1074/jbc.m111087200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27018598

Title: Crystal structure of human myotubularin-related protein 1 provides insight into the structural basis of substrate specificity.

PubMed ID: 27018598

DOI: 10.1371/journal.pone.0152611

Sequence Information:

  • Length: 665
  • Mass: 74678
  • Checksum: 12E766859F0DCA75
  • Sequence:
    • MDRPAAAAAA GCEGGGGPNP GPAGGRRPPR AAGGATAGSR QPSVETLDSP TGSHVEWCKQ 
LIAATISSQI SGSVTSENVS RDYKALRDGN KLAQMEEAPL FPGESIKAIV KDVMYICPFM 
GAVSGTLTVT DFKLYFKNVE RDPHFILDVP LGVISRVEKI GAQSHGDNSC GIEIVCKDMR 
NLRLAYKQEE QSKLGIFENL NKHAFPLSNG QALFAFSYKE KFPINGWKVY DPVSEYKRQG 
LPNESWKISK INSNYEFCDT YPAIIVVPTS VKDDDLSKVA AFRAKGRVPV LSWIHPESQA 
TITRCSQPLV GPNDKRCKED EKYLQTIMDA NAQSHKLIIF DARQNSVADT NKTKGGGYES 
ESAYPNAELV FLEIHNIHVM RESLRKLKEI VYPSIDEARW LSNVDGTHWL EYIRMLLAGA 
VRIADKIESG KTSVVVHCSD GWDRTAQLTS LAMLMLDSYY RTIKGFETLV EKEWISFGHR 
FALRVGHGND NHADADRSPI FLQFVDCVWQ MTRQFPSAFE FNELFLITIL DHLYSCLFGT 
FLCNCEQQRF KEDVYTKTIS LWSYINSQLD EFSNPFFVNY ENHVLYPVAS LSHLELWVNY 
YVRWNPRMRP QMPIHQNLKE LLAVRAELQK RVEGLQREVA TRAVSSSSER GSSPSHSATS 
VHTSV

Genular Protein ID: 505713033

Symbol: Q8NEC6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NEC6

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 GO 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 Proteomes 2 ProteomicsDB 2 RefSeq 2 SAM 1 SMART 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 363
  • Mass: 39822
  • Checksum: 9AE00536BCF60811
  • Sequence:
    • MDRPAAAAAA GCEGGGGPNP GPAGGRRPPR AAGGATAGSR QPSVETLDSP TGSHVEWCKQ 
LIAATISSQI SGSVTSENVS RDYKALRDGN KLAQMEEAPL FPGESIKAIV KDVMYICPFM 
GAVSGTLTVT DFKLYFKNVE RDPHFILDVP LGVISRVEKI GAQSHGDNSC GIEIVCKDMR 
NLRLAYKQEE QSKLGIFENL NKHAFPLSNG QALFAFSYKE KFPINGWKVY DPVSEYKRQG 
LPNESWKISK INSNYEFCDT YPAIIVVPTS VKDDDLSKVA AFRAKGRVPV LSWIHPESQA 
TITRCSQPLV GPNDKRCKED EKYLQTIMDA NAQSHKLIIF DARQNSVADT NKLWYQDTAS 
LME

Genular Protein ID: 869764771

Symbol: F8WA39_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8WA39

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 12 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 HGNC 1 InterPro 10 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSR 2 PROSITE 5 PeptideAtlas 2 Pfam 2 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 3 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 673
  • Mass: 75718
  • Checksum: A838A0F326073100
  • Sequence:
    • MDRPAAAAAA GCEGGGGPNP GPAGGRRPPR AAGGATAGSR QPSVETLDSP TGSHVEWCKQ 
LIAATISSQI SGSVTSENVS RDYKVFRRPD LRALRDGNKL AQMEEAPLFP GESIKAIVKD 
VMYICPFMGA VSGTLTVTDF KLYFKNVERD PHFILDVPLG VISRVEKIGA QSHGDNSCGI 
EIVCKDMRNL RLAYKQEEQS KLGIFENLNK HAFPLSNGQA LFAFSYKEKF PINGWKVYDP 
VSEYKRQGLP NESWKISKIN SNYEFCDTYP AIIVVPTSVK DDDLSKVAAF RAKGRVPVLS 
WIHPESQATI TRCSQPLVGP NDKRCKEDEK YLQTIMDANA QSHKLIIFDA RQNSVADTNK 
TKGGGYESES AYPNAELVFL EIHNIHVMRE SLRKLKEIVY PSIDEARWLS NVDGTHWLEY 
IRMLLAGAVR IADKIESGKT SVVVHCSDGW DRTAQLTSLA MLMLDSYYRT IKGFETLVEK 
EWISFGHRFA LRVGHGNDNH ADADRSPIFL QFVDCVWQMT RQFPSAFEFN ELFLITILDH 
LYSCLFGTFL CNCEQQRFKE DVYTKTISLW SYINSQLDEF SNPFFVNYEN HVLYPVASLS 
HLELWVNYYV RWNPRMRPQM PIHQNLKELL AVRAELQKRV EGLQREVATR AVSSSSERGS 
SPSHSATSVH TSV

Genular Protein ID: 3753717021

Symbol: B7Z3D5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3D5

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 12 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 4 GO 6 Gene3D 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 2 PROSITE 5 PeptideAtlas 1 Pfam 2 ProteomicsDB 1 RefSeq 3 Rhea 3 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 571
  • Mass: 65337
  • Checksum: 99F7CBE0FB4C2AAD
  • Sequence:
    • MEEAPLFPGE SIKAIVKDVM YICPFMGAVS GTLTVTDFKL YFKNVERDPH FILDVPLGVI 
SRVEKIGAQS HGDNSCGIEI VCKDMRNLRL AYKQEEQSKL GIFENLNKHA FPLSNGQALF 
AFSYKEKFPI NGWKVYDPVS EYKRQGLPNE SWKISKINSN YEFCDTYPAI IVVPTSVKDD 
DLSKVAAFRA KGRVPVLSWI HPESQATITR CSQPLVGPND KRCKEDEKYL QTIMDANAQS 
HKLIIFDARQ NSVADTNKTK GGGYESESAY PNAELVFLEI HNIHVMRESL RKLKEIVYPS 
IDEARWLSNV DGTHWLEYIR MLLAGAVRIA DKIESGKTSV VVHCSDGWDR TAQLTSLAML 
MLDSYYRTIK GFETLVEKEW ISFGHRFALR VGHGNDNHAD ADRSPIFLQF VDCVWQMTRQ 
FPSAFEFNEL FLITILDHLY SCLFGTFLCN CEQQRFKEDV YTKTISLWSY INSQLDEFSN 
PFFVNYENHV LYPVASLSHL ELWVNYYVRW NPRMRPQMPI HQNLKELLAV RAELQKRVEG 
LQREVATRAV SSSSERGSSP SHSATSVHTS V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.