Details for: NRP1

Gene ID: 8829

Symbol: NRP1

Ensembl ID: ENSG00000099250

Description: neuropilin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 252.9536
    Cell Significance Index: -64.1600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 127.9752
    Cell Significance Index: -60.4200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 126.6685
    Cell Significance Index: -51.4600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 53.9307
    Cell Significance Index: -51.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 51.7942
    Cell Significance Index: -63.8600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 23.1108
    Cell Significance Index: -50.5800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.1858
    Cell Significance Index: -63.8700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 8.9254
    Cell Significance Index: 128.3700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 5.8484
    Cell Significance Index: 47.6900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 4.7724
    Cell Significance Index: 248.5900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 4.5770
    Cell Significance Index: 89.3300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 4.4063
    Cell Significance Index: 296.2800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.5665
    Cell Significance Index: 95.2300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 3.5126
    Cell Significance Index: 100.2400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 3.4215
    Cell Significance Index: 262.5600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.8169
    Cell Significance Index: 559.0300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.4250
    Cell Significance Index: 11.9700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9754
    Cell Significance Index: 133.9500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.8968
    Cell Significance Index: 13.2400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5659
    Cell Significance Index: 309.0300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5273
    Cell Significance Index: 476.1300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4378
    Cell Significance Index: 43.3100
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.3801
    Cell Significance Index: 5.8800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.3724
    Cell Significance Index: 2.2500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3484
    Cell Significance Index: 69.8800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2134
    Cell Significance Index: 34.7100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1965
    Cell Significance Index: 89.1700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1370
    Cell Significance Index: 9.6900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1192
    Cell Significance Index: 52.7100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1140
    Cell Significance Index: 14.6200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0669
    Cell Significance Index: 46.2700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0318
    Cell Significance Index: 19.8600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0027
    Cell Significance Index: -1.7100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0046
    Cell Significance Index: -8.6300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0114
    Cell Significance Index: -0.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0280
    Cell Significance Index: -3.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0323
    Cell Significance Index: -23.8900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0363
    Cell Significance Index: -66.8600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0426
    Cell Significance Index: -65.6400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0487
    Cell Significance Index: -1.7100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0513
    Cell Significance Index: -69.7600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0738
    Cell Significance Index: -54.1300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0743
    Cell Significance Index: -56.2500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0763
    Cell Significance Index: -4.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0838
    Cell Significance Index: -47.2500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0899
    Cell Significance Index: -2.5900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0945
    Cell Significance Index: -33.8800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.1104
    Cell Significance Index: -19.9100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1166
    Cell Significance Index: -1.3300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1445
    Cell Significance Index: -21.0000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.1508
    Cell Significance Index: -28.7100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1652
    Cell Significance Index: -2.7700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1804
    Cell Significance Index: -51.9000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1868
    Cell Significance Index: -4.6700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2002
    Cell Significance Index: -34.1800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2182
    Cell Significance Index: -45.9600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2331
    Cell Significance Index: -27.1700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2654
    Cell Significance Index: -5.7500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2793
    Cell Significance Index: -28.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.2872
    Cell Significance Index: -35.3100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2930
    Cell Significance Index: -33.5700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.3308
    Cell Significance Index: -22.8800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.4104
    Cell Significance Index: -18.6000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4308
    Cell Significance Index: -25.8700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.4383
    Cell Significance Index: -56.6200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4448
    Cell Significance Index: -12.7500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4786
    Cell Significance Index: -29.4200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5099
    Cell Significance Index: -60.1400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5307
    Cell Significance Index: -60.5800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5461
    Cell Significance Index: -56.8700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5810
    Cell Significance Index: -20.1900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6181
    Cell Significance Index: -37.9000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.6305
    Cell Significance Index: -13.0800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6480
    Cell Significance Index: -10.9200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.6944
    Cell Significance Index: -10.2500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7059
    Cell Significance Index: -55.9100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.7407
    Cell Significance Index: -55.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.7809
    Cell Significance Index: -50.3800
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.7862
    Cell Significance Index: -9.9000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.8096
    Cell Significance Index: -25.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.8474
    Cell Significance Index: -44.4900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.8701
    Cell Significance Index: -15.3800
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.9428
    Cell Significance Index: -12.0900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.9569
    Cell Significance Index: -20.0300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.9619
    Cell Significance Index: -20.5600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.9915
    Cell Significance Index: -46.6000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.0287
    Cell Significance Index: -64.8400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.0634
    Cell Significance Index: -55.2400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.1272
    Cell Significance Index: -35.9000
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -1.1470
    Cell Significance Index: -13.3200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.2651
    Cell Significance Index: -32.5200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.2809
    Cell Significance Index: -59.7200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.3495
    Cell Significance Index: -59.6900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.3543
    Cell Significance Index: -39.8900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.4000
    Cell Significance Index: -70.7500
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -1.4082
    Cell Significance Index: -10.7700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.4486
    Cell Significance Index: -38.0900
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -1.4611
    Cell Significance Index: -15.2200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.4621
    Cell Significance Index: -47.8700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.4699
    Cell Significance Index: -55.6600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NRP1 is a member of the semaphorin receptor family and is characterized by its ability to bind to VEGF and semaphorins, which are key regulators of angiogenesis and axon guidance. NRP1's ligands include VEGF165, semaphorin 3A (Sema3A), and semaphorin 3D (Sema3D). The receptor's extracellular domain contains a binding site for these ligands, while its intracellular domain interacts with various signaling molecules, including GTPase-activating proteins (GAPs) and phosphatases. NRP1's expression is highly dynamic, with changes in its levels and localization occurring in response to developmental, pathological, and environmental cues. **Pathways and Functions** NRP1's signaling pathways are diverse and interconnected, with key roles in: 1. **Angiogenesis**: NRP1's interaction with VEGF165 and Sema3A regulates endothelial cell migration, proliferation, and tube formation, promoting vascular sprouting and branching. 2. **Axon guidance**: NRP1's binding to Sema3A and Sema3D regulates axon extension, fasciculation, and branching, influencing neural development and connectivity. 3. **Cell migration**: NRP1's interaction with VEGF165 and Sema3A regulates endothelial cell migration, influencing vascular development and repair. 4. **Cell proliferation**: NRP1's signaling pathways regulate cellular proliferation, influencing tissue growth and homeostasis. 5. **Apoptosis**: NRP1's interaction with Sema3A and Sema3D regulates neuronal apoptosis, influencing neural development and survival. **Clinical Significance** NRP1's dysregulation has been implicated in various diseases, including: 1. **Cancer**: NRP1's overexpression has been linked to tumor progression, metastasis, and resistance to therapy. 2. **Neurodegenerative disorders**: NRP1's dysregulation has been implicated in Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions. 3. **Cardiovascular diseases**: NRP1's interaction with VEGF165 regulates vascular development and disease, with implications for cardiovascular health. 4. **Infectious diseases**: NRP1's signaling pathways regulate immune cell migration and function, influencing disease pathogenesis. In conclusion, NRP1 is a multifunctional receptor that plays a critical role in various cellular processes, including angiogenesis, axon guidance, and cell migration. Its dysregulation has been implicated in several diseases, highlighting the importance of NRP1 in human health and disease. Further research is needed to elucidate the complex signaling pathways regulated by NRP1 and to explore its therapeutic potential.

Genular Protein ID: 3922739450

Symbol: NRP1_HUMAN

Name: Vascular endothelial cell growth factor 165 receptor

UniProtKB Accession Codes:

O14786 B0LPG9 O60461 Q5T7F1 Q5T7F2 Q5T7F3 Q86T59 Q96I90 Q96IH5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 CORUM 1 CTD 1 ChEBI 3 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 100 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 23 PDBsum 23 PIRSF 1 PRINTS 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 8 RefSeq 4 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9288753

Title: Neuropilin is a receptor for the axonal chemorepellent semaphorin III.

PubMed ID: 9288753

DOI: 10.1016/s0092-8674(00)80534-6

PubMed ID: 9529250

Title: Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor.

PubMed ID: 9529250

DOI: 10.1016/s0092-8674(00)81402-6

PubMed ID: 10688880

Title: Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: in vivo expression and antitumor activity.

PubMed ID: 10688880

DOI: 10.1073/pnas.040337597

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10520995

Title: Plexins are a large family of receptors for transmembrane, secreted and GPI-anchored semaphorins in vertebrates.

PubMed ID: 10520995

DOI: 10.1016/s0092-8674(00)80063-x

PubMed ID: 10748121

Title: Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165.

PubMed ID: 10748121

DOI: 10.1074/jbc.m909259199

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16763549

Title: Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling.

PubMed ID: 16763549

DOI: 10.1038/sj.emboj.7601188

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19805273

Title: C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration.

PubMed ID: 19805273

DOI: 10.1073/pnas.0908201106

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26503042

Title: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.

PubMed ID: 26503042

DOI: 10.1038/nature15510

PubMed ID: 26789244

Title: Corrigendum: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.

PubMed ID: 26789244

DOI: 10.1038/nature16499

PubMed ID: 30623799

Title: Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress.

PubMed ID: 30623799

DOI: 10.1016/j.isci.2018.12.005

PubMed ID: 33000221

Title: Neuropilin-1 as a new potential SARS-CoV-2 infection mediator implicated in the neurologic features and central nervous system involvement of COVID-19.

PubMed ID: 33000221

DOI: 10.3892/mmr.2020.11510

PubMed ID: 33082293

Title: Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity.

PubMed ID: 33082293

DOI: 10.1126/science.abd2985

PubMed ID: 36213313

Title: Mass spectrometric analysis of chondroitin sulfate-linked peptides.

PubMed ID: 36213313

DOI: 10.1007/s42485-022-00092-3

PubMed ID: 12517344

Title: Crystal structure of the human neuropilin-1 b1 domain.

PubMed ID: 12517344

DOI: 10.1016/s0969-2126(02)00941-3

PubMed ID: 17989695

Title: Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.

PubMed ID: 17989695

DOI: 10.1038/sj.emboj.7601906

PubMed ID: 33082294

Title: Neuropilin-1 is a host factor for SARS-CoV-2 infection.

PubMed ID: 33082294

DOI: 10.1126/science.abd3072

Sequence Information:

  • Length: 923
  • Mass: 103134
  • Checksum: 1EAC2FA6C8FD6A0B
  • Sequence:
    • MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA 
PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF 
IKFVSDYETH GAGFSIRYEI FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFVP 
KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS 
GILSMVFYTD SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEIHSDQ ITASSQYSTN 
WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK KKYYVKTYKI 
DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI TRFVRIKPAT WETGISMRFE 
VYGCKITDYP CSGMLGMVSG LISDSQITSS NQGDRNWMPE NIRLVTSRSG WALPPAPHSY 
INEWLQIDLG EEKIVRGIII QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAKSF 
EGNNNYDTPE LRTFPALSTR FIRIYPERAT HGGLGLRMEL LGCEVEAPTA GPTTPNGNLV 
DECDDDQANC HSGTGDDFQL TGGTTVLATE KPTVIDSTIQ SEFPTYGFNC EFGWGSHKTF 
CHWEHDNHVQ LKWSVLTSKT GPIQDHTGDG NFIYSQADEN QKGKVARLVS PVVYSQNSAH 
CMTFWYHMSG SHVGTLRVKL RYQKPEEYDQ LVWMAIGHQG DHWKEGRVLL HKSLKLYQVI 
FEGEIGKGNL GGIAVDDISI NNHISQEDCA KPADLDKKNP EIKIDETGST PGYEGEGEGD 
KNISRKPGNV LKTLDPILIT IIAMSALGVL LGAVCGVVLY CACWHNGMSE RNLSALENYN 
FELVDGVKLK KDKLNTQSTY SEA

Genular Protein ID: 2207949162

Symbol: Q68DN3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q68DN3

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 3 DNASU 1 DisGeNET 1 EMBL 2 GO 17 Gene3D 3 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 3 SAM 3 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 923
  • Mass: 103085
  • Checksum: FA5033CC5B523DEB
  • Sequence:
    • MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA 
PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF 
IKFVSDYETH GAGFSIRYEV FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFAP 
KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS 
GILSMVFYTD SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEIHSDQ ITASSQYSTN 
WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK KKYYVKTYKI 
DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI TRFVRIKPAT WETGISMRFE 
VYGCKITDYP RSGMLGMVSG LISDSQITSS NQGDRNWMPE NIRLVTSRSG WALPPAPHSY 
INEWLQIDLG EEKIVRGIII QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAKSF 
EGNNNYDTPE LRTFPALSTR FIRIYPERAT HGGLGLRMEL LGCEVEAPTA GPTTPNGNLV 
DECDDDQANC HSGTGDDFQL AGGTTVLATE KPTVIDSTIQ SEFPTYGFNC EFGWGSHKTF 
CHWEHDNHVQ LKWSVLTSKT GPIQDHTGDG NFIYSQADEN QKGKVARLVS PVVYSQNSAH 
CMTFWYHMSG SHVGTLRVKL RYQKPEEYDQ LVWMAIGHQG DHWKEGRVLL HKSLKLYQVI 
FEGEIGKGNL GGIAVDDISI NNHISQEDCA KPADLDKKNP EIKIDETGSA PGYEGEGEGD 
KNISRKPGNV LKTLDPILIT IIAMSALGVL LGAVCGVVLY CACWHNGMSE RNLSALENYN 
FELVDGVKLK KDKLNTQSTY SEA

Genular Protein ID: 3681560015

Symbol: Q6X907_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6X907

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 3 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 17 Gene3D 3 InterPro 9 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 3 SMART 3 SMR 1 SUPFAM 3

Sequence Information:

  • Length: 906
  • Mass: 101291
  • Checksum: FB50D01D9E2150A3
  • Sequence:
    • MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA 
PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF 
IKFVSDYETH GAGFSIRYEI FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFAP 
KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS 
GILSMVFYTD SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEIHSDQ ITASSQYSTN 
WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK KKYYVKTYKI 
DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI TRFVRIKPAT WETGISMRFE 
VYGCKITDYP CSGMLGMVSG LISDSQITSS NQGDRNWMPE NIRLVTSRSG WALPPAPHSY 
INEWLQIDLG EEKIVRGIII QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAKSF 
EGNNNYDTPE LRTFPALSTR FIRIYPERAT HGGLGLRMEL LGCEVEAPTA GPTTPNGNLV 
DECDDDQANC HSGTGDDFQL TGGTTVLATE KPTVIDSTIQ SEFPTYGFNC EFGWGSHKTF 
CHWEHDNHVQ LKWSVLTSKT GPIQDHTGDG NFIYSQADEN QKGKVARLVS PVVYSQNSAH 
CMTFWYHMSG SHVGTLRVKL RYQKPEEYHQ LVWMAIGHQG DHWKEGRVLL HKSLKLYQVI 
FEGEIGKGNL GGIAVDDISI NNHISQEDCA RSTPGYEGEG EGDKNISRKP GNVLKTLDPI 
LITIIAMSAL GVLLGAVCGV VLYCACWHNG MSERNLSALE NYNFELVDGV KLKKDKLNTQ 
STYSEA

Genular Protein ID: 2424631618

Symbol: Q6AWA9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6AWA9

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 15 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 538
  • Mass: 60595
  • Checksum: F82FE7542B12FB88
  • Sequence:
    • MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA 
PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF 
IKFVSDYETH GAGFSIRYEI FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFAP 
KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS 
GILSMVFYTD SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEIHSDQ ITASSQYSTN 
WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK KKYYVKTYKI 
DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI TRFVRIKPAT WETGISMRFE 
VYGCKITDYP CSGMLGMVSG LISDSQITSS NQGDRNWMPE NIRLVTSRSG WALPPAPHSY 
INEWLQIDLG EEKIVRGIII QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAK

Genular Protein ID: 2318851131

Symbol: Q59F20_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59F20

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 3 DNASU 1 DisGeNET 1 EMBL 2 GO 17 Gene3D 3 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 3 SAM 2 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 890
  • Mass: 99694
  • Checksum: CAA6CE38A97288CB
  • Sequence:
    • KPQGYLTSPG YPHSYHPSEK CEWLIQAPDP YQRIMINFNP HFDLEDRDCK YDYVEVFDGE 
NENGHFRGKF CGKIAPPPVV SSGPFLFIKF VSDYETHGAG FSIRYEIFKR GPECSQNYTT 
PSGVIKSPGF PEKYPNSLEC TYIVFAPKMS EIILEFESFD LEPDSNPPGG MFCRYDRLEI 
WDGFPDVGPH IGRYCGQKTP GRIRSSSGIL SMVFYTDSAI AKEGFSANYS VLQSSVSEDF 
KCMEALGMES GEIHSDQITA SSQYSTNWSA ERSRLNYPEN GWTPGEDSYR EWIQVDLGLL 
RFVTAVGTQG AISKETKKKY YVKTYKIDVS SNGEDWITIK EGNKPVLFQG NTNPTDVVVA 
VFPKPLITRF VRIKPATWET GISMRFEVYG CKITDYPCSG MLGMVSGLIS DSQITSSNQG 
DRNWMPENIR LVTSRSGWAL PPAPHSYINE WLQIDLGEEK IVRGIIIQGG KHRENKVFMR 
KFKIGYSNNG SDWKMIMDDS KRKAKSFEGN NNYDTPELRT FPALSTRFIR IYPERATHGG 
LGLRMELLGC EVEAPTAGPT TPNGNLVDEC DDDQANCHSG TGDDFQLTGG TTVLATEKPT 
VIDSTIQSEF PTYGFNCEFG WGSHKTFCHW EHDNHVQLKW SVLTSKTGPI QDHTGDGNFI 
YSQADENQKG KVARLVSPVV YSQNSAHCMT FWYHMSGSHV GTLRVKLRYQ KPEEYDQLVW 
MAIGHQGDHW KEGRVLLHKS LKLYQVIFEG EIGKGNLGGI AVDDISINNH ISQEDCAKPA 
DLDKKNPEIK IDETGSTPGY EGEGEGDKNI SRKPGNVLKT LDPILITIIA MSALGVLLGA 
VCGVVLYCAC WHNGMSERNL SALENYNFEL VDGVKLKKDK LNTQSTYSEA

Genular Protein ID: 908619957

Symbol: A8K9V7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K9V7

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 3 DNASU 1 DisGeNET 1 EMBL 2 GO 17 Gene3D 3 InterPro 9 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 3 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 917
  • Mass: 102358
  • Checksum: F203D77DD6BD1279
  • Sequence:
    • MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA 
PDPYQRIMIN FNPHFDLEVR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF 
IKFVSDYETH GAGFSIRYEI FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFAP 
KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS 
GILSMVFYTD SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEIHSDQ ITASSQYSTN 
WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK KKYYVKTYKI 
DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI TRFVRIKPAT WETGISMRFE 
VYGCKITDYP CSGMLGMVSG LISDSQITSS NQGDRNWMPE NIRLVTSRSG WALPPAPHSY 
INEWLQIDLG EEKIVRGIII QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAKSF 
EGNNNYDTPE LRTFPALSTR FIRIYPERAT HGGLGLRMEL LGCEVEAPTA GPTTPNGNLV 
DECDDDQASC HSGTGGTTVL ATEKPTVIDS TIQSEFPTYG FNCEFGWGSH KTFCHWEHDN 
HVQLKWSVLT SKTGPIQDHT AGDGNFIYSQ ADENQKGKVA RLVSPVVYSQ NSAHCMTFWY 
HMSGSHVGTL RVKLRYQKPE EYDQLVWMAI GHQGDHWKEG RVLLHKSLKL YQVIFEGEIG 
KGNLGGIAVD DISINNHISQ EDCAKPADLD KKNPEIKIDE TGSTPGYEGE GEGDKNISRK 
PGNVLKTIDP ILITIIAMSA LGVLLGAVCG VVLYCACWHN GMSERNLSAL ENYNFELVDG 
VKLKKDKLNT QSTYSEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.