Details for: MAP7

Gene ID: 9053

Symbol: MAP7

Ensembl ID: ENSG00000135525

Description: microtubule associated protein 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 421.0351
    Cell Significance Index: -65.4900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 227.6424
    Cell Significance Index: -57.7400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 139.7306
    Cell Significance Index: -65.9700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 125.0686
    Cell Significance Index: -50.8100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 98.1786
    Cell Significance Index: -65.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 54.9493
    Cell Significance Index: -67.7500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 53.2395
    Cell Significance Index: -50.8300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 24.0139
    Cell Significance Index: -64.3300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 17.3743
    Cell Significance Index: -68.5600
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 11.1886
    Cell Significance Index: 86.2400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.5734
    Cell Significance Index: -16.5800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 5.6856
    Cell Significance Index: 70.5200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 4.4010
    Cell Significance Index: 125.5900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 4.2766
    Cell Significance Index: 287.5600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.5206
    Cell Significance Index: 133.3200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.4704
    Cell Significance Index: 1244.7700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.4549
    Cell Significance Index: 152.8200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.8590
    Cell Significance Index: 573.5200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.6943
    Cell Significance Index: 122.1300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.3502
    Cell Significance Index: 255.6300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 2.3105
    Cell Significance Index: 269.2600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.2908
    Cell Significance Index: 119.0000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.1085
    Cell Significance Index: 58.9300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.9888
    Cell Significance Index: 57.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.7149
    Cell Significance Index: 1186.1200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.5385
    Cell Significance Index: 18.3400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.5222
    Cell Significance Index: 95.9400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.3978
    Cell Significance Index: 73.3900
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 1.2090
    Cell Significance Index: 10.6500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.1648
    Cell Significance Index: 209.9800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.0430
    Cell Significance Index: 28.3900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9952
    Cell Significance Index: 122.3700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.9410
    Cell Significance Index: 8.6700
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.8118
    Cell Significance Index: 9.8400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.7171
    Cell Significance Index: 40.2400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6711
    Cell Significance Index: 109.1500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.6544
    Cell Significance Index: 30.5100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.5888
    Cell Significance Index: 10.0900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.5372
    Cell Significance Index: 8.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5061
    Cell Significance Index: 100.4300
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.4997
    Cell Significance Index: 6.4800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4558
    Cell Significance Index: 16.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4474
    Cell Significance Index: 842.4700
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.4146
    Cell Significance Index: 3.6800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3616
    Cell Significance Index: 197.4700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3328
    Cell Significance Index: 211.3500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3300
    Cell Significance Index: 32.6400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.3194
    Cell Significance Index: 6.6300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.3030
    Cell Significance Index: 412.0600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2852
    Cell Significance Index: 48.7000
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.2696
    Cell Significance Index: 2.7200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2686
    Cell Significance Index: 4.5300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2524
    Cell Significance Index: 388.5400
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.2434
    Cell Significance Index: 2.7500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1968
    Cell Significance Index: 87.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1521
    Cell Significance Index: 280.5200
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.1051
    Cell Significance Index: 1.4700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0697
    Cell Significance Index: 13.2600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0462
    Cell Significance Index: 5.9700
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.0446
    Cell Significance Index: 0.2800
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.0328
    Cell Significance Index: 0.4600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0313
    Cell Significance Index: 1.8800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0066
    Cell Significance Index: 0.4900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0016
    Cell Significance Index: 0.7300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0004
    Cell Significance Index: -0.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0013
    Cell Significance Index: -0.0600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0136
    Cell Significance Index: -1.9800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0143
    Cell Significance Index: -8.9200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0234
    Cell Significance Index: -17.3700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0426
    Cell Significance Index: -24.0100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0453
    Cell Significance Index: -33.1800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0623
    Cell Significance Index: -47.1300
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0700
    Cell Significance Index: -0.7500
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0757
    Cell Significance Index: -0.7200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1236
    Cell Significance Index: -3.9600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1276
    Cell Significance Index: -26.8800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1592
    Cell Significance Index: -3.9800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1960
    Cell Significance Index: -56.4000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2052
    Cell Significance Index: -2.8000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.2632
    Cell Significance Index: -18.2100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2797
    Cell Significance Index: -6.0600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2971
    Cell Significance Index: -34.0400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3105
    Cell Significance Index: -6.5900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3306
    Cell Significance Index: -20.3200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.3439
    Cell Significance Index: -35.1300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3699
    Cell Significance Index: -8.8700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3800
    Cell Significance Index: -24.5200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.4179
    Cell Significance Index: -57.3900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4379
    Cell Significance Index: -33.6100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4388
    Cell Significance Index: -9.4800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4473
    Cell Significance Index: -46.5700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.4678
    Cell Significance Index: -6.2400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4795
    Cell Significance Index: -54.7300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4797
    Cell Significance Index: -9.6300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4991
    Cell Significance Index: -12.7500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.4992
    Cell Significance Index: -64.0000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5519
    Cell Significance Index: -65.0800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5790
    Cell Significance Index: -7.2200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6678
    Cell Significance Index: -52.8900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.6939
    Cell Significance Index: -13.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MAP7 is a microtubule-associated protein that belongs to the 14-3-3 family of proteins. It is characterized by its ability to interact with microtubules, thereby regulating microtubule dynamics and stability. MAP7 is widely expressed in various cell types, including chromaffin cells, oligodendrocytes, and neurons, where it plays a crucial role in maintaining cellular polarity. **Pathways and Functions:** MAP7 is involved in several key pathways, including: 1. **Establishment or maintenance of cell polarity**: MAP7 regulates the organization of microtubules at the cell surface, thereby maintaining cellular polarity and ensuring proper cell signaling and morphology. 2. **Microtubule cytoskeleton organization**: MAP7 interacts with microtubules and other cytoskeletal proteins to regulate microtubule dynamics and organization, which is essential for cell movement, division, and signaling. 3. **Protein binding and localization**: MAP7 binds to various proteins, including microtubules, kinases, and signaling molecules, thereby regulating their localization and activity. 4. **Signaling receptor binding**: MAP7 interacts with signaling receptors, such as GABA receptors, to modulate their activity and signaling pathways. **Clinical Significance:** Dysregulation of MAP7 has been implicated in several neurological disorders, including: 1. **Neurodegenerative diseases**: Mutations in MAP7 have been associated with neurodegenerative diseases, such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS). 2. **Neurodevelopmental disorders**: MAP7 dysregulation has been linked to neurodevelopmental disorders, such as autism spectrum disorder and schizophrenia. 3. **Cancer**: MAP7 has been implicated in cancer development and progression, particularly in glioblastoma and other brain tumors. In conclusion, MAP7 is a critical protein that plays a central role in maintaining cellular polarity, regulating microtubule dynamics, and modulating signaling pathways. Its dysregulation has been implicated in various neurological and cancer disorders, highlighting the importance of MAP7 in human health and disease. Further research is needed to fully elucidate the functions of MAP7 and its potential therapeutic applications.

Genular Protein ID: 998215856

Symbol: MAP7_HUMAN

Name: Ensconsin

UniProtKB Accession Codes:

Q14244 B7Z290 B7Z400 B7Z5S7 B7Z9U7 C9JPS0 E9PCP3 F5H1E2 Q7Z6S0 Q8TAU5 Q9NY82 Q9NY83

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 7 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 EMDB 3 Ensembl 8 ExpressionAtlas 1 GO 13 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 Pumba 1 RNAct 1 RefSeq 12 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8408219

Title: Identification and molecular characterization of E-MAP-115, a novel microtubule-associated protein predominantly expressed in epithelial cells.

PubMed ID: 8408219

DOI: 10.1083/jcb.123.2.357

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7490279

Title: Binding of E-MAP-115 to microtubules is regulated by cell cycle-dependent phosphorylation.

PubMed ID: 7490279

DOI: 10.1083/jcb.131.4.1015

PubMed ID: 9989799

Title: Upregulation and redistribution of E-MAP-115 (epithelial microtubule-associated protein of 115 kDa) in terminally differentiating keratinocytes is coincident with the formation of intercellular contacts.

PubMed ID: 9989799

DOI: 10.1046/j.1523-1747.1999.00500.x

PubMed ID: 11719555

Title: Rapid dynamics of the microtubule binding of ensconsin in vivo.

PubMed ID: 11719555

DOI: 10.1242/jcs.114.21.3885

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 749
  • Mass: 84052
  • Checksum: CB69BDE25C9540E3
  • Sequence:
    • MAELGAGGDG HRGGDGAVRS ETAPDSYKVQ DKKNASSRPA SAISGQNNNH SGNKPDPPPV 
LRVDDRQRLA RERREEREKQ LAAREIVWLE REERARQHYE KHLEERKKRL EEQRQKEERR 
RAAVEEKRRQ RLEEDKERHE AVVRRTMERS QKPKQKHNRW SWGGSLHGSP SIHSADPDRR 
SVSTMNLSKY VDPVISKRLS SSSATLLNSP DRARRLQLSP WESSVVNRLL TPTHSFLARS 
KSTAALSGEA ASCSPIIMPY KAAHSRNSMD RPKLFVTPPE GSSRRRIIHG TASYKKERER 
ENVLFLTSGT RRAVSPSNPK ARQPARSRLW LPSKSLPHLP GTPRPTSSLP PGSVKAAPAQ 
VRPPSPGNIR PVKREVKVEP EKKDPEKEPQ KVANEPSLKG RAPLVKVEEA TVEERTPAEP 
EVGPAAPAMA PAPASAPAPA SAPAPAPVPT PAMVSAPSST VNASASVKTS AGTTDPEEAT 
RLLAEKRRLA REQREKEERE RREQEELERQ KREELAQRVA EERTTRREEE SRRLEAEQAR 
EKEEQLQRQA EERALREREE AERAQRQKEE EARVREEAER VRQEREKHFQ REEQERLERK 
KRLEEIMKRT RRTEATDKKT SDQRNGDIAK GALTGGTEVS ALPCTTNAPG NGKPVGSPHV 
VTSHQSKVTV ESTPDLEKQP NENGVSVQNE NFEEIINLPI GSKPSRLDVT NSESPEIPLN 
PILAFDDEGT LGPLPQVDGV QTQQTAEVI

Genular Protein ID: 2999816422

Symbol: B7Z3Y3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3Y3

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 603
  • Mass: 66968
  • Checksum: 611EED484E200AE2
  • Sequence:
    • MERSQKPKQK HNRWSWGGSL HGSPSIHSAD PDRRSVSTMN LSKYVDPVIS KRLSSSSATL 
LNSPDRARRL QLSPWESSVV NRLLTPTHSF LARSKSTAAL SGEAASCSPI IMPYKAAHSR 
NSMDRPKLFV TPPEGSSRRR IIHGTASYKK ERERENVLFL TSGTRRAVSP SNPKARQPAR 
SRLWLPSKSL PHLPGTPRPT SSLPPGSVKA APAQVRPPSP GNIRPVKREV KVEPEKKDPE 
KEPQKVANEP SLKGRAPLVK VEEATVEERT PAEPEVGPAA PAMAPAPASA PAPASAPAPA 
PVPTPAMVSA PSSTVNASAS VKTSAGTTDP EEATRLLAEK RRLAREQREK EERERREQEE 
LERQKREELA QRVAEERTTR REEESRRLEA EQAREKEEQL QRQAEERALR EWEEAERAQR 
QKEEEARVRE EAERVRQERE KHFQREEQER LERKKRLEEI MKRTRRTEAT DKKTSDQRNG 
DIAKGALTGG TEVSALPCTT NAPGNGKPVG SPHVVTSHQS KVTVESTPDL EKQPNENGVS 
VQNENFEEII NLPIGSKPSR LDVTNSESPE IPLNPILAFD DEGTLGPLPQ VDGVQTQQTA 
EVI

Genular Protein ID: 1410173387

Symbol: B7Z3E1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3E1

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 611
  • Mass: 67834
  • Checksum: 9102342F29C99832
  • Sequence:
    • MERSQKPKQK HNRWSWGGSL HGSPSIHSAD PDRRSVSTMN LSKYVDPVIS KRLSSSSATL 
LNSPDRARRL QLSPWESSVV NRLLTPTHSF LARSKSTAAL SGEAVIPICP RSASCSPIIM 
PYKAAHSRNS MDRPKLFVTP PEGSSRRRII HGTASYKKER ERENVLFLTS GTRRAVSPSN 
PKARQPARSR LWLPSKSLPH LPGTPRPTSS LPPGSVKAAP AQVRPPSPGN IRPVKREVKV 
EPEKKDPEKE PQKVANEPSL KGRAPLVKVE EATVEERTPA EPEVGPAAPA MAPAPASAPA 
PASAPAPAPV PTPAMVSAPS STVNASASVK TSAGTTDPEE ATRLLAEKRR LAREQREKEE 
RERREQEELE RQKREELAQR VAEERTTRRE EESRRLEAEQ AREKEEQLQR QAEERALREW 
EEAERAQRQK EEEARVREEA ERVRQEREKH FQREEQERLE RKKRLEEIMK RTRRTEATDK 
KTSDQRNGDI AKGALTGGTE VSALPCTTNA PGNGKPVGSP HVVTSHQSKV TVESTPDLEK 
QPNENGVSVQ NENFEEIINL PIGSKPSRLD VTNSESPEIP LNPILAFDDE GTLGPLPQVD 
GVQTQQTAEV I

Genular Protein ID: 1207908134

Symbol: A0A087WZ40_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WZ40

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 3 GeneTree 1 HGNC 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 3 SAM 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 779
  • Mass: 87818
  • Checksum: 5D122957EDB49570
  • Sequence:
    • MPGSATALRH ERLKKTNARP IPLGLFTINE EDEQQKNGNS RRPKAPDSYK VQDKKNASSR 
PASAISGQNN NHSGNKPDPP PVLRVDDRQR LARERREERE KQLAAREIVW LEREERARQH 
YEKHLEERKK RLEEQRQKEE RRRAAVEEKR RQRLEEDKER HEAVVRRTME RSQKPKQKHN 
RWSWGGSLHG SPSIHSADPD RRSVSTMNLS KYVDPVISKR LSSSSATLLN SPDRARRLQL 
SPWESSVVNR LLTPTHSFLA RSKSTAALSG EAVIPICPRS ASCSPIIMPY KAAHSRNSMD 
RPKLFVTPPE GSSRRRIIHG TASYKKERER ENVLFLTSGT RRAVSPSNPK ARQPARSRLW 
LPSKSLPHLP GTPRPTSSLP PGSVKAAPAQ VRPPSPGNIR PVKREVKVEP EKKDPEKEPQ 
KVANEPSLKG RAPLVKVEEA TVEERTPAEP EVGPAAPAMA PAPASAPAPA SAPAPAPVPT 
PAMVSAPSST VNASASVKTS AGTTDPEEAT RLLAEKRRLA REQREKEERE RREQEELERQ 
KREELAQRVA EERTTRREEE SRRLEAEQAR EKEEQLQRQA EERALREREE AERAQRQKEE 
EARVREEAER VRQEREKHFQ REEQERLERK KRLEEIMKRT RRTEATDKKT SDQRNGDIAK 
GALTGGTEVS ALPCTTNAPG NGKPVGSPHV VTSHQSKVTV ESTPDLEKQP NENGVSVQNE 
NFEEIINLPI GSKPSRLDVT NSESPEIPLN PILAFDDEGT LGPLPQVDGV QTQQTAEVI

Genular Protein ID: 336529707

Symbol: B7ZB64_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZB64

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 771
  • Mass: 86956
  • Checksum: C26447726B7DB1AE
  • Sequence:
    • MPGSATALRH ERLKKTNARP IPLGLFTINE EDEQQKNGNS RRPKAPDSYK VQDKKNASSR 
PASAISGQNN NHSGNKPDPP PVLRVDDRQR LARERREERE KQLAAREIVW LEREERARQH 
YEKHLEERKK RLEEQRQKEE RRRAAVEEKR RQRLEEDKER HEAVVRRTME RSQKPKQKHN 
RWSWGGSLHG SPSIHSADPD RRSVSTMNLS KYVDPVISKR LSSSSATSLN SPDRARRLQL 
SPWESSVVNR LLTPTHSFLA RSKSTAALSG EAASCSPIIM PYKAAHSRNS MDRPKLFVTP 
PEGSSRRRII HGTASYKKER ERENVLFLTS GTRRAVSPSN PKARQPARSR LWLPSKSLPH 
LPGTPRPTSS LPPGSVKAAP AQVRPPSPGN IRPVKREVKV EPEKKDPEKE PQKVANEPSL 
KGRAPLVKVE EATVEERTPA EPEVGPAAPA MAPAPASAPA PASAPAPAPV PTPAMVSAPS 
STVNASASVK TSAGTTDPEE ATRLLAEKRR LAREQREKEE RERREQEELE RQKREELAQR 
VAEERTTRRE EESRRLEAEQ AREKEEQLQR QAEERALREW EEAERAQRQK EEEARVREEA 
ERVRQEREKH FQREEQERLE RKKRLEEIMK RTRRTEATDK KTSDQRNGDI AKGALTGGTE 
VSALPCTTNA PGNGKPVGSP HVVTSHQSKV TVESTPDLEK QPNENGVSVQ NENFEEIINL 
PIGSKPSRLD VTNSESPEIP LNPILAFDDE GTLGPLPQVD GVQTQQTAEV I

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.