Details for: FEZ1

Gene ID: 9638

Symbol: FEZ1

Ensembl ID: ENSG00000149557

Description: fasciculation and elongation protein zeta 1

Associated with

Other Information

Genular Protein ID: 210216464

Symbol: FEZ1_HUMAN

Name: Fasciculation and elongation protein zeta-1

UniProtKB Accession Codes:

Q99689 O00679 O00728 Q6IBI7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 22 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 4 SAM 1 SIGNOR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9096408

Title: The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation.

PubMed ID: 9096408

DOI: 10.1073/pnas.94.7.3414

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15466860

Title: Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis.

PubMed ID: 15466860

DOI: 10.1074/jbc.m402916200

PubMed ID: 16484223

Title: FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region.

PubMed ID: 16484223

DOI: 10.1074/jbc.m513280200

PubMed ID: 18439996

Title: Over-expression of GFP-FEZ1 causes generation of multi-lobulated nuclei mediated by microtubules in HEK293 cells.

PubMed ID: 18439996

DOI: 10.1016/j.yexcr.2008.02.012

PubMed ID: 20812761

Title: Human FEZ1 protein forms a disulfide bond mediated dimer: implications for cargo transport.

PubMed ID: 20812761

DOI: 10.1021/pr100314q

PubMed ID: 22354037

Title: Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.

PubMed ID: 22354037

DOI: 10.1038/emboj.2012.36

PubMed ID: 24098481

Title: Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation.

PubMed ID: 24098481

DOI: 10.1371/journal.pone.0076355

Sequence Information:

  • Length: 392
  • Mass: 45119
  • Checksum: 4226ED5EA17706F2
  • Sequence:
    • MEAPLVSLDE EFEDLRPSCS EDPEEKPQCF YGSSPHHLED PSLSELENFS SEIISFKSME 
DLVNEFDEKL NVCFRNYNAK TENLAPVKNQ LQIQEEEETL QDEEVWDALT DNYIPSLSED 
WRDPNIEALN GNCSDTEIHE KEEEEFNEKS ENDSGINEEP LLTADQVIEE IEEMMQNSPD 
PEEEEEVLEE EDGGETSSQA DSVLLQEMQA LTQTFNNNWS YEGLRHMSGS ELTELLDQVE 
GAIRDFSEEL VQQLARRDEL EFEKEVKNSF ITVLIEVQNK QKEQRELMKK RRKEKGLSLQ 
SSRIEKGNQM PLKRFSMEGI SNILQSGIRQ TFGSSGTDKQ YLNTVIPYEK KASPPSVEDL 
QMLTNILFAM KEDNEKVPTL LTDYILKVLC PT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.