Details for: DAB2

Gene ID: 1601

Symbol: DAB2

Ensembl ID: ENSG00000153071

Description: DAB adaptor protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 201.1634
    Cell Significance Index: -31.2900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 113.4664
    Cell Significance Index: -28.7800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 101.4085
    Cell Significance Index: -41.7800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 70.1280
    Cell Significance Index: -28.4900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 68.9016
    Cell Significance Index: -32.5300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 65.2818
    Cell Significance Index: -33.5800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 29.8614
    Cell Significance Index: -28.5100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 25.3861
    Cell Significance Index: -31.3000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.8509
    Cell Significance Index: -30.9800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 5.6639
    Cell Significance Index: 87.6300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 4.9057
    Cell Significance Index: 45.1800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.7916
    Cell Significance Index: 108.6900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.7044
    Cell Significance Index: 99.2600
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 3.3056
    Cell Significance Index: 8.7200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 3.1086
    Cell Significance Index: 24.8200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 2.1632
    Cell Significance Index: 17.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.5709
    Cell Significance Index: 155.4000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.5369
    Cell Significance Index: 17.4600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.4234
    Cell Significance Index: 27.7800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.3032
    Cell Significance Index: 27.7600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.1806
    Cell Significance Index: 55.4900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.1743
    Cell Significance Index: 161.2700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.1305
    Cell Significance Index: 24.1700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.0323
    Cell Significance Index: 23.8500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.8542
    Cell Significance Index: 17.8800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8066
    Cell Significance Index: 131.1800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6153
    Cell Significance Index: 36.9400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.4200
    Cell Significance Index: 11.0500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2989
    Cell Significance Index: 13.5500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2214
    Cell Significance Index: 39.9200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2148
    Cell Significance Index: 27.5400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.1780
    Cell Significance Index: 3.1500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.1670
    Cell Significance Index: 4.4600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1098
    Cell Significance Index: 12.8000
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.1055
    Cell Significance Index: 0.6200
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.0660
    Cell Significance Index: 0.5400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0508
    Cell Significance Index: 2.5700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0488
    Cell Significance Index: 4.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0453
    Cell Significance Index: 9.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0162
    Cell Significance Index: 29.8400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0145
    Cell Significance Index: 10.0000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0139
    Cell Significance Index: 21.4700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0061
    Cell Significance Index: 4.4400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0053
    Cell Significance Index: 0.1100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0052
    Cell Significance Index: 0.1500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0051
    Cell Significance Index: 0.0900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0028
    Cell Significance Index: 0.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0004
    Cell Significance Index: 0.3100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0022
    Cell Significance Index: -0.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0063
    Cell Significance Index: -0.2200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0073
    Cell Significance Index: -13.7900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0161
    Cell Significance Index: -11.9400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0197
    Cell Significance Index: -0.9200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0222
    Cell Significance Index: -0.4800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0236
    Cell Significance Index: -13.3000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0238
    Cell Significance Index: -14.8700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0247
    Cell Significance Index: -33.6400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0317
    Cell Significance Index: -6.3000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0326
    Cell Significance Index: -6.2100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0452
    Cell Significance Index: -28.7200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0497
    Cell Significance Index: -21.9700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0606
    Cell Significance Index: -3.1600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0633
    Cell Significance Index: -34.5600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0658
    Cell Significance Index: -11.2300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0723
    Cell Significance Index: -5.7300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0756
    Cell Significance Index: -34.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0779
    Cell Significance Index: -8.9200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0824
    Cell Significance Index: -29.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0864
    Cell Significance Index: -24.8500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0942
    Cell Significance Index: -0.9800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1036
    Cell Significance Index: -21.8200
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.1053
    Cell Significance Index: -1.0000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1132
    Cell Significance Index: -14.6200
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.1897
    Cell Significance Index: -1.4500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2015
    Cell Significance Index: -5.3900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2106
    Cell Significance Index: -30.6100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2378
    Cell Significance Index: -27.1400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2980
    Cell Significance Index: -35.1400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3023
    Cell Significance Index: -31.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3146
    Cell Significance Index: -16.3400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.3160
    Cell Significance Index: -1.9600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3542
    Cell Significance Index: -25.0500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3756
    Cell Significance Index: -28.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4224
    Cell Significance Index: -31.4800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4924
    Cell Significance Index: -17.1100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.5149
    Cell Significance Index: -33.2200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5175
    Cell Significance Index: -34.8000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5177
    Cell Significance Index: -29.0500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.5360
    Cell Significance Index: -23.3100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5518
    Cell Significance Index: -33.8300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.5528
    Cell Significance Index: -33.9800
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.5570
    Cell Significance Index: -4.0000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5951
    Cell Significance Index: -37.5100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.6215
    Cell Significance Index: -17.3700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6276
    Cell Significance Index: -20.1000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.6288
    Cell Significance Index: -9.4800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6384
    Cell Significance Index: -33.5200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6822
    Cell Significance Index: -23.9000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6866
    Cell Significance Index: -30.3700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.6966
    Cell Significance Index: -12.8800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Adaptor Protein Function:** DAB2 acts as a cytoplasmic adaptor protein, bridging signaling molecules and facilitating their interactions with downstream targets. 2. **Endocytosis and Exocytosis:** DAB2 is involved in clathrin-mediated endocytosis and regulates the formation and trafficking of clathrin-coated vesicles. 3. **Apoptosis and Cell Survival:** DAB2 modulates apoptosis and cell survival by interacting with pro-survival and pro-apoptotic signaling pathways. 4. **Immune Response:** DAB2 is expressed in immune cells, such as macrophages and dendritic cells, and regulates immune responses, including antigen presentation and cytokine production. 5. **Cell Signaling:** DAB2 interacts with various signaling pathways, including the Wnt/β-catenin, PI3K/Akt, and MAPK/ERK pathways. **Pathways and Functions:** DAB2's interactions with multiple signaling pathways have been implicated in various cellular processes, including: 1. **Apoptotic Process:** DAB2 regulates apoptosis by interacting with pro-apoptotic and anti-apoptotic proteins, modulating the activity of key players in the apoptotic pathway. 2. **Clathrin-Mediated Endocytosis:** DAB2 is involved in the regulation of clathrin-coated vesicle formation and trafficking, affecting the endocytosis of various proteins and lipids. 3. **Immune Response:** DAB2 regulates immune responses by interacting with immune cells, such as macrophages and dendritic cells, and modulating the production of cytokines and chemokines. 4. **Cell Growth and Migration:** DAB2 regulates cell growth and migration by interacting with signaling pathways involved in these processes, including the PI3K/Akt and MAPK/ERK pathways. 5. **Cancer Biology:** DAB2's role in regulating cell growth, apoptosis, and immune response makes it a potential target for cancer therapy. **Clinical Significance:** DAB2's involvement in various cellular processes makes it a valuable gene for research in: 1. **Immunotherapy:** DAB2's role in regulating immune responses makes it a potential target for immunotherapy in cancer and autoimmune diseases. 2. **Cancer Biology:** DAB2's involvement in cell growth, apoptosis, and immune response makes it a potential target for cancer therapy. 3. **Neurological Disorders:** DAB2's role in regulating neuronal survival and development makes it a potential target for research in neurological disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Inflammatory Diseases:** DAB2's involvement in immune responses makes it a potential target for research in inflammatory diseases, such as rheumatoid arthritis and atherosclerosis. In conclusion, DAB2 is a multifaceted gene involved in various cellular processes, including endocytosis, apoptosis, and immune response. Its involvement in multiple signaling pathways makes it a valuable target for research in immunology, cancer biology, and cellular signaling.

Genular Protein ID: 3171767950

Symbol: DAB2_HUMAN

Name: Disabled homolog 2

UniProtKB Accession Codes:

P98082 A6NES5 Q13598 Q9BTY0 Q9UK04

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 9 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 48 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 4 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8660969

Title: Sequence, genomic structure, and chromosomal assignment of human DOC-2.

PubMed ID: 8660969

DOI: 10.1006/geno.1996.0185

PubMed ID: 9620555

Title: DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer.

PubMed ID: 9620555

DOI: 10.1038/sj.onc.1201769

PubMed ID: 10340382

Title: Disabled-2 inactivation is an early step in ovarian tumorigenicity.

PubMed ID: 10340382

DOI: 10.1038/sj.onc.1202649

PubMed ID: 11161789

Title: Structure, sequence, and promoter analysis of human disabled-2 gene (DAB2).

PubMed ID: 11161789

DOI: 10.1006/geno.2000.6383

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8314147

Title: Molecular cloning of differentially expressed genes in human epithelial ovarian cancer.

PubMed ID: 8314147

DOI: 10.1006/gyno.1994.1040

PubMed ID: 10769163

Title: Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin.

PubMed ID: 10769163

DOI: 10.1042/bj3470613

PubMed ID: 11387212

Title: The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.

PubMed ID: 11387212

DOI: 10.1093/emboj/20.11.2789

PubMed ID: 11967127

Title: Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton.

PubMed ID: 11967127

DOI: 10.1034/j.1600-0854.2002.30503.x

PubMed ID: 12805222

Title: Regulation of the Wnt signaling pathway by disabled-2 (Dab2).

PubMed ID: 12805222

DOI: 10.1093/emboj/cdg286

PubMed ID: 14596919

Title: Dab2 links CIN85 with clathrin-mediated receptor internalization.

PubMed ID: 14596919

DOI: 10.1016/s0014-5793(03)01111-6

PubMed ID: 15134832

Title: The adaptor disabled-2 binds to the third psi xNPxY sequence on the cytoplasmic tail of megalin.

PubMed ID: 15134832

DOI: 10.1016/j.biochi.2004.03.001

PubMed ID: 16267015

Title: The role of DOC-2/DAB2 in modulating androgen receptor-mediated cell growth via the nongenomic c-Src-mediated pathway in normal prostatic epithelium and cancer.

PubMed ID: 16267015

DOI: 10.1158/0008-5472.can-05-1481

PubMed ID: 16984970

Title: The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH.

PubMed ID: 16984970

DOI: 10.1242/jcs.03217

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19306879

Title: Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins.

PubMed ID: 19306879

DOI: 10.1016/j.febslet.2009.03.037

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21097498

Title: Negative regulation of the endocytic adaptor disabled-2 (Dab2) in mitosis.

PubMed ID: 21097498

DOI: 10.1074/jbc.m110.161851

PubMed ID: 21995445

Title: Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator.

PubMed ID: 21995445

DOI: 10.1042/bj20111566

PubMed ID: 22491013

Title: Disabled-2 (Dab2) inhibits Wnt/beta-catenin signalling by binding LRP6 and promoting its internalization through clathrin.

PubMed ID: 22491013

DOI: 10.1038/emboj.2012.83

PubMed ID: 22323290

Title: FCH domain only-2 organizes clathrin-coated structures and interacts with Disabled-2 for low-density lipoprotein receptor endocytosis.

PubMed ID: 22323290

DOI: 10.1091/mbc.e11-09-0812

PubMed ID: 22484487

Title: Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning.

PubMed ID: 22484487

DOI: 10.1038/ncb2473

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 770
  • Mass: 82448
  • Checksum: 5B2F8B510A580A77
  • Sequence:
    • MSNEVETSAT NGQPDQQAAP KAPSKKEKKK GPEKTDEYLL ARFKGDGVKY KAKLIGIDDV 
PDARGDKMSQ DSMMKLKGMA AAGRSQGQHK QRIWVNISLS GIKIIDEKTG VIEHEHPVNK 
ISFIARDVTD NRAFGYVCGG EGQHQFFAIK TGQQAEPLVV DLKDLFQVIY NVKKKEEEKK 
KIEEASKAVE NGSEALMILD DQTNKLKSGV DQMDLFGDMS TPPDLNSPTE SKDILLVDLN 
SEIDTNQNSL RENPFLTNGI TSCSLPRPTP QASFLPENAF SANLNFFPTP NPDPFRDDPF 
TQPDQSTPSS FDSLKSPDQK KENSSSSSTP LSNGPLNGDV DYFGQQFDQI SNRTGKQEAQ 
AGPWPFSSSQ TQPAVRTQNG VSEREQNGFS VKSSPNPFVG SPPKGLSIQN GVKQDLESSV 
QSSPHDSIAI IPPPQSTKPG RGRRTAKSSA NDLLASDIFA PPVSEPSGQA SPTGQPTALQ 
PNPLDLFKTS APAPVGPLVG LGGVTVTLPQ AGPWNTASLV FNQSPSMAPG AMMGGQPSGF 
SQPVIFGTSP AVSGWNQPSP FAASTPPPVP VVWGPSASVA PNAWSTTSPL GNPFQSNIFP 
APAVSTQPPS MHSSLLVTPP QPPPRAGPPK DISSDAFTAL DPLGDKEIKD VKEMFKDFQL 
RQPPAVPARK GEQTSSGTLS AFASYFNSKV GIPQENADHD DFDANQLLNK INEPPKPAPR 
QVSLPVTKST DNAFENPFFK DSFGSSQASV ASSQPVSSEM YRDPFGNPFA

Genular Protein ID: 1310421438

Symbol: B2RAW0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RAW0

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 770
  • Mass: 82470
  • Checksum: 74F97161244AE6A7
  • Sequence:
    • MSNEVETSAT NGQPDQQAAP KAPSKKEKKK GPEKTDEYLL ARFKGDGVKY KAKLIGIDDV 
PDARGDKMSQ DSMMKLKGMA AAGRSQGQHK QRIWVNISLS GIKIIDEKTG VIEHEHPVNK 
ISFIARDVTD NRAFGYVCGG EGQHQFFAIK TGQQAEPLVV DLKDLFQVIY NVKKKEEEKK 
KIEEASKAVE NGSEALMILD DQTNKLKSGV DQMDLFGDMS TPPDLNSPTE SKDILLVDLN 
SEIDTNQNSL RENPFLTNGI TSCSLPRPTP QASFLPENAF SANLNFFPTP NPDPFRDDPF 
TQPDQSTPSS FDSLKSPDQK KENSSSSSTP LSNGPLNGDV DYFGQQFDQI SNRTGKQEAQ 
AGPWPFSSSQ TQPAVRTQNG VSEREQNGFS VKSSPNPFVG SPPKGLSIQN GVKQDLESSV 
QSSPHDSIAI IPPPQSTKPG RGRRTAKSSA NDLLASDIFA PPVSEPSGQA SPTGQPTALQ 
PNPLDLFKTS APAPVGPLVG LGGVIVTLPQ AGPWNTASLV FNQSPSMAPG AMMGGQPSGF 
SQPVIFGTSP AVSGWNQPSP FAASTPPPVP VVWGPSASVA PNAWSTTSPL GNPFQSNIFP 
APAVSTQPPS MHSPLLVTPP QPPPRAGPPK DISSDAFTAL DPLGDKEIKD VKEMFKDFQL 
RQPPAVPARK GEQTSSGTLS AFASYFNSKV GIPQENADHD DFDANQLLNK INEPPKPAPR 
QVSLPVTKST DNAFENPFFK DSFGSSQASV ASSQPVSSEM YRDPFGNPFA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.