Details for: DMBT1

Gene ID: 1755

Symbol: DMBT1

Ensembl ID: ENSG00000187908

Description: deleted in malignant brain tumors 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 3.64
    Marker Score: 3244
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: 2.89
    Marker Score: 1155
  • Cell Name: tracheobronchial serous cell (CL0019001)
    Fold Change: 2.3
    Marker Score: 839
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 2.07
    Marker Score: 3322
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.74
    Marker Score: 656
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.52
    Marker Score: 2874
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 1.48
    Marker Score: 358
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.47
    Marker Score: 7034
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.29
    Marker Score: 3056
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.24
    Marker Score: 581
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 1.23
    Marker Score: 389
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.1
    Marker Score: 7172
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.04
    Marker Score: 2364
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.04
    Marker Score: 257
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71820
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48045
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 0.98
    Marker Score: 2038
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 506
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30407
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 459
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.96
    Marker Score: 1551
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2412
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5352
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.94
    Marker Score: 14639
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.92
    Marker Score: 915
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2739
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.9
    Marker Score: 1824
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 322
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5283
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.85
    Marker Score: 243
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.84
    Marker Score: 1343
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.83
    Marker Score: 1278
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.78
    Marker Score: 311.5
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.77
    Marker Score: 12324
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 393
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.73
    Marker Score: 670
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.72
    Marker Score: 431
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.68
    Marker Score: 2846
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 0.62
    Marker Score: 428
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.59
    Marker Score: 179
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.55
    Marker Score: 264
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 441
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.51
    Marker Score: 230
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.51
    Marker Score: 234
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.49
    Marker Score: 1550
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: 0.48
    Marker Score: 124
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.46
    Marker Score: 273
  • Cell Name: type L enteroendocrine cell (CL0002279)
    Fold Change: 0.45
    Marker Score: 124
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.44
    Marker Score: 126
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.43
    Marker Score: 214
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.43
    Marker Score: 430
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: 0.41
    Marker Score: 179
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.41
    Marker Score: 260
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.38
    Marker Score: 156
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 0.37
    Marker Score: 352
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.36
    Marker Score: 105
  • Cell Name: epithelial fate stem cell (CL0000036)
    Fold Change: 0.36
    Marker Score: 102
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.35
    Marker Score: 157
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.34
    Marker Score: 177
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.32
    Marker Score: 1696
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 0.32
    Marker Score: 96
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.28
    Marker Score: 190
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.28
    Marker Score: 197
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.28
    Marker Score: 71
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.28
    Marker Score: 100
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.26
    Marker Score: 317
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.26
    Marker Score: 385
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.26
    Marker Score: 88
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.25
    Marker Score: 228
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 0.25
    Marker Score: 200
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 0.23
    Marker Score: 67
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.23
    Marker Score: 221
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.22
    Marker Score: 71
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.22
    Marker Score: 63
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 0.22
    Marker Score: 47
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 0.22
    Marker Score: 431
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.21
    Marker Score: 239
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.21
    Marker Score: 162
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.21
    Marker Score: 233
  • Cell Name: type I enteroendocrine cell (CL0002277)
    Fold Change: 0.21
    Marker Score: 52
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.2
    Marker Score: 212
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.19
    Marker Score: 204.5
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.19
    Marker Score: 796.5
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.19
    Marker Score: 61
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.19
    Marker Score: 220
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.18
    Marker Score: 426
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.18
    Marker Score: 329
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.18
    Marker Score: 60
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.17
    Marker Score: 54
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.17
    Marker Score: 122
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.17
    Marker Score: 61
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.16
    Marker Score: 51
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.16
    Marker Score: 158
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.15
    Marker Score: 2027
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.15
    Marker Score: 145
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 0.14
    Marker Score: 960
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.14
    Marker Score: 186
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.14
    Marker Score: 28
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 0.14
    Marker Score: 64
  • Cell Name: enterocyte of epithelium proper of ileum (CL1000342)
    Fold Change: 0.13
    Marker Score: 39

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Other Information

**Key characteristics:** * The DMBT1 gene is located on chromosome 17p13.1. * It is a tumor suppressor gene, meaning that it helps to prevent the growth of cancer cells. * It is frequently deleted in MBTs, which are tumors that develop from cells of the immune system. * The protein encoded by DMBT1 is involved in the regulation of the immune response. **Pathways and functions:** * DMBT1 is involved in the calcium-dependent protein binding pathway, which is a major regulator of the immune response. * It is also involved in the defense response to gram-negative and gram-positive bacteria, the defense response to viruses, and the endocytosis pathway. * It is also involved in the regulation of epithelial cell differentiation, the induction of bacterial agglutination, and the innate immune response. **Clinical significance:** * Mutations in the DMBT1 gene have been linked to the development of MBTs. * Targeting DMBT1 has been explored as a treatment for MBTs, but it has not been successful so far. * Further research is needed to understand the role of DMBT1 in cancer and to develop effective treatments for MBTs. **Additional notes:** * DMBT1 is a relatively highly expressed gene in many normal tissues. * It is expressed in high levels in cells of the immune system, including macrophages, dendritic cells, and lymphocytes. * Mutations in DMBT1 have been shown to be associated with the development of several types of cancer, including breast cancer, lung cancer, and colon cancer.

Genular Protein ID: 2469427301

Symbol: DMBT1_HUMAN

Name: Deleted in malignant brain tumors 1 protein

UniProtKB Accession Codes:

Q9UGM3 A6NDG4 A6NDJ5 A8E4R5 B1ARE7 B1ARE8 B1ARE9 B1ARF0 B7Z8Y2 F8WEF7 Q59EX0 Q5JR26 Q6MZN4 Q96DU4 Q9UGM2 Q9UJ57 Q9UKJ4 Q9Y211 Q9Y4V9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 11 ExpressionAtlas 1 GO 19 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 3 PIR 1 PRIDE 1 PRINTS 1 PRO 1 PROSITE 5 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 9 Pumba 1 RNAct 1 Reactome 1 RefSeq 7 SAM 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9288095

Title: DMBT1, a new member of the SRCR superfamily on chromosome 10q25.3-q26.1 is deleted in malignant brain tumours.

PubMed ID: 9288095

DOI: 10.1038/ng0997-32

PubMed ID: 10485905

Title: Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D.

PubMed ID: 10485905

DOI: 10.1073/pnas.96.19.10794

PubMed ID: 10597221

Title: The genomic structure of the DMBT1 gene: evidence for a region with susceptibility to genomic instability.

PubMed ID: 10597221

DOI: 10.1038/sj.onc.1203071

PubMed ID: 10551316

Title: Expression of the DMBT1 gene is frequently suppressed in human lung cancer.

PubMed ID: 10551316

DOI: 10.1111/j.1349-7006.1999.tb00833.x

PubMed ID: 11751412

Title: Deleted in malignant brain tumors 1 is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer.

PubMed ID: 11751412

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 25946035

Title: Human basal tear peptidome characterization by CID, HCD, and ETD followed by in silico and in vitro analyses for antimicrobial peptide identification.

PubMed ID: 25946035

DOI: 10.1021/acs.jproteome.5b00179

PubMed ID: 9153228

Title: Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule.

PubMed ID: 9153228

DOI: 10.1074/jbc.272.21.13743

PubMed ID: 10101009

Title: Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates alveolar macrophage migration in an SP-A-independent manner.

PubMed ID: 10101009

DOI: 10.1165/ajrcmb.20.4.3439

PubMed ID: 9888459

Title: Lack of DMBT1 expression in oesophageal, gastric and colon cancers.

PubMed ID: 9888459

DOI: 10.1038/sj.bjc.6690035

PubMed ID: 10749143

Title: DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer.

PubMed ID: 10749143

PubMed ID: 11007786

Title: Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340.

PubMed ID: 11007786

DOI: 10.1074/jbc.m006928200

PubMed ID: 15355985

Title: Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains.

PubMed ID: 15355985

DOI: 10.1074/jbc.m406095200

PubMed ID: 16796526

Title: The N-terminal SRCR-SID domain of gp-340 interacts with HIV type 1 gp120 sequences and inhibits viral infection.

PubMed ID: 16796526

DOI: 10.1089/aid.2006.22.508

PubMed ID: 16740002

Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

PubMed ID: 16740002

DOI: 10.1021/pr050492k

PubMed ID: 17983803

Title: DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease.

PubMed ID: 17983803

DOI: 10.1053/j.gastro.2007.08.007

PubMed ID: 17548659

Title: Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.

PubMed ID: 17548659

DOI: 10.4049/jimmunol.178.12.8203

PubMed ID: 17709527

Title: gp340 expressed on human genital epithelia binds HIV-1 envelope protein and facilitates viral transmission.

PubMed ID: 17709527

DOI: 10.4049/jimmunol.179.5.3126

PubMed ID: 18713006

Title: A common binding motif for various bacteria of the bacteria-binding peptide SRCRP2 of DMBT1/gp-340/salivary agglutinin.

PubMed ID: 18713006

DOI: 10.1515/bc.2008.135

PubMed ID: 19189310

Title: DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands.

PubMed ID: 19189310

DOI: 10.1002/eji.200838689

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23439307

Title: Staphylococcus aureus SasA is responsible for binding to the salivary agglutinin gp340, derived from human saliva.

PubMed ID: 23439307

DOI: 10.1128/iai.00011-13

PubMed ID: 12353266

Title: The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer.

PubMed ID: 12353266

DOI: 10.1002/gcc.10115

PubMed ID: 12185598

Title: Rare mutations of the DMBT1 gene in human astrocytic gliomas.

PubMed ID: 12185598

DOI: 10.1038/sj.onc.1205733

PubMed ID: 28397838

Title: Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.

PubMed ID: 28397838

DOI: 10.1038/mp.2017.60

Sequence Information:

  • Length: 2413
  • Mass: 260735
  • Checksum: 25363E6263234F15
  • Sequence:
    • MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF PSESTLESTV 
AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL ALRLVNGDGR CQGRVEILYR 
GSWGTVCDDS WDTNDANVVC RQLGCGWAMS APGNAWFGQG SGPIALDDVR CSGHESYLWS 
CPHNGWLSHN CGHGEDAGVI CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG 
DRCRGRVEVL YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD 
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS HASTAGPESS 
LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV CRQLGCGWAT SAPGNARFGQ 
GSGPIVLDDV RCSGYESYLW SCPHNGWLSH NCQHSEDAGV ICSAAHSWST PSPDTLPTIT 
LPASTVGSES SLALRLVNGG DRCQGRVEVL YRGSWGTVCD DSWDTNDANV VCRQLGCGWA 
MLAPGNARFG QGSGPIVLDD VRCSGNESYL WSCPHNGWLS HNCGHSEDAG VICSGPESSL 
ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTNDANVVC RQLGCGWATS APGNARFGQG 
SGPIVLDDVR CSGHESYLWS CPNNGWLSHN CGHHEDAGVI CSAAQSRSTP RPDTLSTITL 
PPSTVGSESS LTLRLVNGSD RCQGRVEVLY RGSWGTVCDD SWDTNDANVV CRQLGCGWAT 
SAPGNARFGQ GSGPIVLDDV RCSGHESYLW SCPHNGWLSH NCGHHEDAGV ICSVSQSRPT 
PSPDTWPTSH ASTAGPESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTSDANVVC 
RQLGCGWATS APGNARFGQG SGPIVLDDVR CSGYESYLWS CPHNGWLSHN CQHSEDAGVI 
CSAAHSWSTP SPDTLPTITL PASTVGSESS LALRLVNGGD RCQGRVEVLY QGSWGTVCDD 
SWDTNDANVV CRQLGCGWAM SAPGNARFGQ GSGPIVLDDV RCSGHESYLW SCPHNGWLSH 
NCGHSEDAGV ICSASQSRPT PSPDTWPTSH ASTAGSESSL ALRLVNGGDR CQGRVEVLYR 
GSWGTVCDDY WDTNDANVVC RQLGCGWAMS APGNARFGQG SGPIVLDDVR CSGHESYLWS 
CPHNGWLSHN CGHHEDAGVI CSASQSQPTP SPDTWPTSHA STAGSESSLA LRLVNGGDRC 
QGRVEVLYRG SWGTVCDDYW DTNDANVVCR QLGCGWATSA PGNARFGQGS GPIVLDDVRC 
SGHESYLWSC PHNGWLSHNC GHHEDAGVIC SASQSQPTPS PDTWPTSHAS TAGSESSLAL 
RLVNGGDRCQ GRVEVLYRGS WGTVCDDYWD TNDANVVCRQ LGCGWATSAP GNARFGQGSG 
PIVLDDVRCS GHESYLWSCP HNGWLSHNCG HHEDAGVICS ASQSQPTPSP DTWPTSRAST 
AGSESTLALR LVNGGDRCRG RVEVLYQGSW GTVCDDYWDT NDANVVCRQL GCGWAMSAPG 
NAQFGQGSGP IVLDDVRCSG HESYLWSCPH NGWLSHNCGH HEDAGVICSA AQSQSTPRPD 
TWLTTNLPAL TVGSESSLAL RLVNGGDRCR GRVEVLYRGS WGTVCDDSWD TNDANVVCRQ 
LGCGWAMSAP GNARFGQGSG PIVLDDVRCS GNESYLWSCP HKGWLTHNCG HHEDAGVICS 
ATQINSTTTD WWHPTTTTTA RPSSNCGGFL FYASGTFSSP SYPAYYPNNA KCVWEIEVNS 
GYRINLGFSN LKLEAHHNCS FDYVEIFDGS LNSSLLLGKI CNDTRQIFTS SYNRMTIHFR 
SDISFQNTGF LAWYNSFPSD ATLRLVNLNS SYGLCAGRVE IYHGGTWGTV CDDSWTIQEA 
EVVCRQLGCG RAVSALGNAY FGSGSGPITL DDVECSGTES TLWQCRNRGW FSHNCNHRED 
AGVICSGNHL STPAPFLNIT RPNTDYSCGG FLSQPSGDFS SPFYPGNYPN NAKCVWDIEV 
QNNYRVTVIF RDVQLEGGCN YDYIEVFDGP YRSSPLIARV CDGARGSFTS SSNFMSIRFI 
SDHSITRRGF RAEYYSSPSN DSTNLLCLPN HMQASVSRSY LQSLGFSASD LVISTWNGYY 
ECRPQITPNL VIFTIPYSGC GTFKQADNDT IDYSNFLTAA VSGGIIKRRT DLRIHVSCRM 
LQNTWVDTMY IANDTIHVAN NTIQVEEVQY GNFDVNISFY TSSSFLYPVT SRPYYVDLNQ 
DLYVQAEILH SDAVLTLFVD TCVASPYSND FTSLTYDLIR SGCVRDDTYG PYSSPSLRIA 
RFRFRAFHFL NRFPSVYLRC KMVVCRAYDP SSRCYRGCVL RSKRDVGSYQ EKVDVVLGPI 
QLQTPPRREE EPR

Genular Protein ID: 3276539820

Symbol: A0A590UJ76_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A590UJ76

Database IDs:

ARBA 10 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 DNASU 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 4 GeneTree 1 HGNC 1 InterPro 8 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 8 PROSITE-ProRule 2 PeptideAtlas 2 Pfam 3 Proteomes 2 RefSeq 1 SAM 2 SMART 3 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

Sequence Information:

  • Length: 2412
  • Mass: 260633
  • Checksum: BED99F08A4979027
  • Sequence:
    • MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF PSESTLESTV 
AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL ALRLVNGDGR CQGRVEILYR 
GSWGTVCDDS WDTNDANVVC RQLGCGWAMS APGNAWFGQG SGPIALDDVR CSGHESYLWS 
CPHNGWLSHN CGHGEDAGVI CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG 
DRCRGRVEVL YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD 
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS HASTAGPESS 
LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV CRQLGCGWAT SAPGNARFGQ 
GSGPIVLDDV RCSGYESYLW SCPHNGWLSH NCQHSEDAGV ICSAAHSWST PSPDTLPTIT 
LPASTVGSES SLALRLVNGG DRCQGRVEVL YRGSWGTVCD DSWDTNDANV VCRQLGCGWA 
MLAPGNARFG QGSGPIVLDD VRCSGNESYL WSCPHNGWLS HNCGHSEDAG VICSGPESSL 
ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTNDANVVC RQLGCGWATS APGNARFGQG 
SGPIVLDDVR CSGHESYLWS CPNNGWLSHN CGHHEDAGVI CSAAQSRSTP RPDTLSTITL 
PPSTVGSESS LTLRLVNGSD RCQGRVEVLY RGSWGTVCDD SWDTNDANVV CRQLGCGWAT 
SAPGNARFGQ GSGPIVLDDV RCSGHESYLW SCPHNGWLSH NCGHHEDAGV ICSVSQSRPT 
PSPDTWPTSH ASTAGPESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTSDANVVC 
RQLGCGWATS APGNARFGQG SGPIVLDDVR CSGYESYLWS CPHNGWLSHN CQHSEDAGVI 
CSAAHSWSTP SPDTLPTITL PASTVGSESS LALRLVNGGD RCQGRVEVLY QGSWGTVCDD 
SWDTNDANVV CRQLGCGWAM SAPGNARFGQ GSGPIVLDDV RCSGHESYLW SCPHNGWLSH 
NCGHSEDAGV ICSASQSRPT PSPDTWPTSH ASTAGSESSL ALRLVNGGDR CQGRVEVLYR 
GSWGTVCDDY WDTNDANVVC RQLGCGWAMS APGNARFGQG SGPIVLDDVR CSGHESYLWS 
CPHNGWLSHN CGHHEDAGVI CSASQSQPTP SPDTWPTSHA STAGSESSLA LRLVNGGDRC 
QGRVEVLYRG SWGTVCDDYW DTNDANVVCR QLGCGWATSA PGNARFGQGS GPIVLDDVRC 
SGHESYLWSC PHNGWLSHNC GHHEDAGVIC SASQSQPTPS PDTWPTSHAS TAGSESSLAL 
RLVNGGDRCQ GRVEVLYRGS WGTVCDDYWD TNDANVVCRQ LGCGWATSAP GNARFGQGSG 
PIVLDDVRCS GHESYLWSCP HNGWLSHNCG HHEDAGVICS ASQSQPTPSP DTWPTSRAST 
AGSESTLALR LVNGGDRCRG RVEVLYQGSW GTVCDDYWDT NDANVVCRQL GCGWAMSAPG 
NAQFGQGSGP IVLDDVRCSG HESYLWSCPH NGWLSHNCGH HEDAGVICSA AQSQSTPRPD 
TWLTTNLPAL TVGSESSLAL RLVNGGDRCR GRVEVLYRGS WGTVCDDSWD TNDANVVCRQ 
LGCGWAMSAP GNARFGQGSG PIVLDDVRCS GNESYLWSCP HKGWLTHNCG HHEDAGVICS 
ATQINSTTTD WWHPTTTTTA RPSSNCGGFL FYASGTFSSP SYPAYYPNNA KCVWEIEVNS 
GYRINLGFSN LKLEAHHNCS FDYVEIFDGS LNSSLLLGKI CNDTRQIFTS SYNRMTIHFR 
SDISFQNTGF LAWYNSFPSD ATLRLVNLNS SYGLCAGRVE IYHGGTWGTV CDDSWTIQEA 
EVVCRQLGCG RAVSALGNAY FGSGSGPITL DDVECSGTES TLWQCRNRGW FSHNCNHRED 
AGVICSGNHL STPAPFLNIT RPNNYSCGGF LSQPSGDFSS PFYPGNYPNN AKCVWDIEVQ 
NNYRVTVIFR DVQLEGGCNY DYIEVFDGPY RSSPLIARVC DGARGSFTSS SNFMSIRFIS 
DHSITRRGFR AEYYSSPSND STNLLCLPNH MQASVSRSYL QSLGFSASDL VISTWNGYYE 
CRPQITPNLV IFTIPYSGCG TFKQADNDTI DYSNFLTAAV SGGIIKRRTD LRIHVSCRML 
QNTWVDTMYI ANDTIHVANN TIQVEEVQYG NFDVNISFYT SSSFLYPVTS RPYYVDLNQD 
LYVQAEILHS DAVLTLFVDT CVASPYSNDF TSLTYDLIRS GCVRDDTYGP YSSPSLRIAR 
FRFRAFHFLN RFPSVYLRCK MVVCRAYDPS SRCYRGCVLR SKRDVGSYQE KVDVVLGPIQ 
LQTPPRREEE PR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.